What airlines fly to Greenville?

American Airlines, Southwest and Frontier are the top three most popular airlines that fly to Greenville from Harrisburg according to our data. American Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 7 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Harrisburg to Greenville?

Allegiant Air and United Airlines are the most popular carriers operating from Harrisburg to Greenville

When did momondo last update prices for flights from Harrisburg Airport to Greenville Airport?

Prices for flights from Harrisburg Airport to Greenville Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Harrisburg Airport to Greenville Airport?

There are 3 operators available for flights from Harrisburg Airport to Greenville Airport as of October 2025.

How old do you have to be to fly from Harrisburg Airport to Greenville Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$185 Cheap Flights from Harrisburg to Greenville in 2025/26

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Find the cheapest flights from Harrisburg to Greenville

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:12 pm - 11:45 pmMDT-GSP

4h 33m1 stop

5:35 am - 10:59 amGSP-MDT

5h 24m1 stop

$229Delta

Find Deal

Mon, Nov 17 - Mon, Nov 24

4:25 pm - 11:00 pmMDT-GSP

6h 35m1 stop

6:00 am - 10:24 amGSP-MDT

4h 24m1 stop

$239American Airlines

Find Deal

Tue, Nov 11 - Sat, Nov 15

2:55 pm - 11:00 pmMDT-GSP

8h 05m2 stops

11:33 am - 3:01 pmGSP-MDT

3h 28m1 stop

$244American Airlines

Find Deal

Tue, Nov 11 - Sat, Nov 15

6:00 am - 11:02 amMDT-GSP

5h 02m1 stop

6:29 pm - 11:07 pmGSP-MDT

4h 38m1 stop

$264Delta

Find Deal

Thu, Dec 4 - Mon, Dec 8

9:12 pm - 2:46 pmMDT-GSP

17h 34m1 stop

4:16 pm - 8:43 amGSP-MDT

16h 27m2 stops

$287Multiple Airlines

Find Deal

Sat, Nov 15 - Wed, Nov 19

11:31 am - 9:42 pmMDT-GSP

10h 11m2 stops

6:01 am - 2:29 pmGSP-MDT

8h 28m2 stops

$304American Airlines

Find Deal

Sat, Nov 15 - Wed, Nov 19

5:00 am - 8:25 amMDT-GSP

3h 25m1 stop

12:17 pm - 3:30 pmGSP-MDT

3h 13m1 stop

$305American Airlines

Find Deal

Thu, Dec 4 - Wed, Dec 10

6:00 am - 11:00 amMDT-GSP

5h 00m1 stop

6:45 am - 11:37 amGSP-MDT

4h 52m1 stop

$308Delta

Find Deal

Sat, Mar 28 - Wed, Apr 1

6:30 am - 11:47 amMDT-GSP

5h 17m1 stop

9:10 am - 4:53 pmGSP-MDT

7h 43m1 stop

$339United Airlines

Find Deal

Tue, Nov 11 - Sat, Nov 15

6:30 am - 11:49 amMDT-GSP

5h 19m1 stop

9:10 am - 1:58 pmGSP-MDT

28h 48m2 stops

$448United Airlines

Find Deal

Wed, Nov 12 - Sat, Nov 15

Delta flights from Harrisburg to Greenville

Our best Delta deals on Harrisburg to Greenville flight tickets

Delta

Nov 17

MDT7:12 pmHarrisburg

4h 33m

1 stop

GSP11:45 pmGreenville

Nov 24

GSP5:35 amGreenville

5h 24m

1 stop

MDT10:59 amHarrisburg

$229

Find similar

Delta

Dec 4

MDT6:00 amHarrisburg

5h 02m

1 stop

GSP11:02 amGreenville

Dec 8

GSP6:29 pmGreenville

4h 38m

1 stop

MDT11:07 pmHarrisburg

$264

Find similar

Delta

Mar 28

MDT6:00 amHarrisburg

5h 00m

1 stop

GSP11:00 amGreenville

Apr 1

GSP6:45 amGreenville

4h 52m

1 stop

MDT11:37 amHarrisburg

$308

Find similar

American Airlines flights from Harrisburg to Greenville

Our best American Airlines deals on Harrisburg to Greenville flight tickets

American Airlines

Nov 11

MDT4:25 pmHarrisburg

6h 35m

1 stop

GSP11:00 pmGreenville

Nov 15

GSP6:00 amGreenville

4h 24m

1 stop

MDT10:24 amHarrisburg

$239

Find similar

American Airlines

Nov 11

MDT2:55 pmHarrisburg

8h 05m

2 stops

GSP11:00 pmGreenville

Nov 15

GSP11:33 amGreenville

3h 28m

1 stop

MDT3:01 pmHarrisburg

$244

Find similar

American Airlines

Oct 30

MDT6:15 amHarrisburg

4h 05m

1 stop

GSP10:20 amGreenville

Nov 1

GSP7:21 amGreenville

6h 00m

1 stop

MDT1:21 pmHarrisburg

$299

Find similar

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Mon 11/17

7:12 pm-11:45 pm

1 stop4h 33m

Greenville

Mon 11/24

5:35 am-10:59 am

1 stop5h 24m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 11/11

4:25 pm-11:00 pm

1 stop6h 35m

Greenville

Sat 11/15

6:00 am-10:24 am

1 stop4h 24m

$239

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 11/11

2:55 pm-11:00 pm

2 stops8h 05m

Greenville

Sat 11/15

11:33 am-3:01 pm

1 stop3h 28m

$244

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 12/4

6:00 am-11:02 am

1 stop5h 02m

Greenville

Mon 12/8

6:29 pm-11:07 pm

1 stop4h 38m

$264

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 11/15

9:12 pm-2:46 pm

1 stop17h 34m

Greenville

Wed 11/19

4:16 pm-8:43 am

2 stops16h 27m

$287

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 11/15

11:31 am-9:42 pm

2 stops10h 11m

Greenville

Wed 11/19

6:01 am-2:29 pm

2 stops8h 28m

$304

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 12/4

5:00 am-8:25 am

1 stop3h 25m

Greenville

Wed 12/10

12:17 pm-3:30 pm

1 stop3h 13m

$305

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 3/28

6:00 am-11:00 am

1 stop5h 00m

Greenville

Wed 4/1

6:45 am-11:37 am

1 stop4h 52m

$308

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 11/11

6:30 am-11:47 am

1 stop5h 17m

Greenville

Sat 11/15

9:10 am-4:53 pm

1 stop7h 43m

$339

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 11/12

6:30 am-11:49 am

1 stop5h 19m

Greenville

Sat 11/15

9:10 am-1:58 pm

2 stops28h 48m

$448

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first

How to get the cheapest flight ticket from Harrisburg to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Harrisburg averaging around $267.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Harrisburg. The lowest ticket price found for a Wednesday departure recently was $293. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $526. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Harrisburg to Greenville during this time can be as low as $293. Flights to Greenville are more costly at noon, with an average ticket price of $452. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Harrisburg to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Greenville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Harrisburg to Greenville (MDT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Greenville

Direct flights	None

There are no direct flights from Harrisburg to Greenville. There are no popular flight routes from Harrisburg to Greenville.

Search flight deals

How far is Harrisburg to Greenville by plane?
Greenville is 480.4 mi away from Harrisburg. By plane, this route typically takes 3h 25m.
When did momondo last update prices for flights from Harrisburg Airport to Greenville Airport?
Prices for flights from Harrisburg Airport to Greenville Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Harrisburg Airport to Greenville Airport?
There are 3 operators available for flights from Harrisburg Airport to Greenville Airport as of October 2025.
How old do you have to be to fly from Harrisburg Airport to Greenville Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Harrisburg to Greenville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Harrisburg to Greenville is American Airlines (79% of total bookings). The next most popular airlines are United Airlines (14%) and Delta (7%).

Best airlines flying from Harrisburg to Greenville

Compare and see reviews for airlines that fly from Harrisburg to Greenville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.2 11,033 reviews	Search American Airlines flights
Delta	PriceFrom $228	Free Cancellation	Rating 7.9 7,996 reviews	Search Delta flights
United Airlines	PriceFrom $233	Free Cancellation	Rating 7.4 8,997 reviews	Search United Airlines flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Harrisburg to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Harrisburg to Greenville with flexible booking policies on momondo?

Flights from Harrisburg to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Harrisburg to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Harrisburg to Greenville.

I’m not ready to book a flight from Harrisburg to Greenville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Harrisburg to Greenville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.