What airlines fly to Greenville?

American Airlines, Frontier and Southwest are the top three most popular airlines that fly to Greenville from Harrisburg according to our data. American Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 7 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Harrisburg to Greenville?

Delta, Allegiant Air, and United Airlines are the most popular carriers operating from Harrisburg to Greenville

When did momondo last update prices for flights from Harrisburg Airport to Greenville Airport?

Prices for flights from Harrisburg Airport to Greenville Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Harrisburg Airport to Greenville Airport?

There are 3 operators available for flights from Harrisburg Airport to Greenville Airport as of August 2025.

How old do you have to be to fly from Harrisburg Airport to Greenville Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$156 Cheap Flights from Harrisburg to Greenville (MDT-GSP) in 2025

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Find the cheapest flights from Harrisburg to Greenville (MDT-GSP)

Round-trip

One-way

Last minute

Cheap round-trip flights

11:31 am - 5:51 pmMDT-GSP

6h 20m1 stop

6:00 am - 10:24 amGSP-MDT

4h 24m1 stop

$259American Airlines

Find Deal

Sat, Nov 8 - Sun, Nov 9

7:30 am - 12:28 pmMDT-GSP

4h 58m1 stop

6:19 pm - 10:11 pmGSP-MDT

3h 52m1 stop

$268American Airlines

Find Deal

Thu, Sep 25 - Mon, Sep 29

5:00 am - 8:35 amMDT-GSP

3h 35m1 stop

6:40 pm - 12:19 amGSP-MDT

5h 39m1 stop

$298American Airlines

Find Deal

Fri, Nov 21 - Sun, Nov 23

6:30 pm - 10:58 pmMDT-GSP

4h 28m1 stop

10:53 am - 3:01 pmGSP-MDT

4h 08m1 stop

$333American Airlines

Find Deal

Fri, Sep 12 - Mon, Sep 15

6:00 am - 11:29 amMDT-GSP

5h 29m1 stop

6:30 pm - 11:29 pmGSP-MDT

4h 59m1 stop

$346Delta

Find Deal

Sat, Sep 6 - Sat, Sep 6

6:10 am - 1:20 pmMDT-GSP

7h 10m2 stops

6:30 pm - 11:29 pmGSP-MDT

4h 59m1 stop

$351Delta

Find Deal

Sat, Sep 6 - Sat, Sep 6

10:30 am - 2:16 pmMDT-GSP

3h 46m1 stop

10:05 am - 1:54 pmGSP-MDT

3h 49m1 stop

$355United Airlines

Find Deal

Sat, Sep 20 - Sat, Sep 27

6:45 am - 11:56 amMDT-GSP

5h 11m1 stop

6:02 am - 1:48 pmGSP-MDT

7h 46m1 stop

$398United Airlines

Find Deal

Tue, Sep 9 - Sat, Sep 13

10:30 am - 2:16 pmMDT-GSP

3h 46m1 stop

5:34 pm - 1:54 pmGSP-MDT

20h 20m2 stops

$461United Airlines

Find Deal

Sat, Sep 20 - Sat, Sep 27

12:33 pm - 7:23 pmMDT-GSP

6h 50m1 stop

6:54 pm - 11:01 pmGSP-MDT

4h 07m1 stop

$510Delta

Find Deal

Mon, Sep 8 - Fri, Sep 12

United Airlines flights from Harrisburg to Greenville

Our best United Airlines deals on Harrisburg to Greenville flight tickets

United Airlines

Sep 20

MDT10:30 amHarrisburg

3h 46m

1 stop

GSP2:16 pmGreenville

Sep 27

GSP10:05 amGreenville

3h 49m

1 stop

MDT1:54 pmHarrisburg

$355

Find similar

United Airlines

Sep 2

MDT5:48 pmHarrisburg

4h 58m

1 stop

GSP10:46 pmGreenville

Sep 5

GSP6:02 amGreenville

3h 31m

1 stop

MDT9:33 amHarrisburg

$377

Find similar

United Airlines

Sep 9

MDT6:45 amHarrisburg

5h 11m

1 stop

GSP11:56 amGreenville

Sep 13

GSP6:02 amGreenville

7h 46m

1 stop

MDT1:48 pmHarrisburg

$398

Find similar

Delta flights from Harrisburg to Greenville

Our best Delta deals on Harrisburg to Greenville flight tickets

Delta

Sep 6

MDT6:00 amHarrisburg

5h 29m

1 stop

GSP11:29 amGreenville

Sep 6

GSP6:30 pmGreenville

4h 59m

1 stop

MDT11:29 pmHarrisburg

$346

Find similar

Delta

Sep 6

MDT6:10 amHarrisburg

7h 10m

2 stops

GSP1:20 pmGreenville

Sep 6

GSP6:30 pmGreenville

4h 59m

1 stop

MDT11:29 pmHarrisburg

$351

Find similar

Delta

Sep 2

MDT12:33 pmHarrisburg

6h 50m

1 stop

GSP7:23 pmGreenville

Sep 5

GSP5:30 amGreenville

6h 22m

2 stops

MDT11:52 amHarrisburg

$465

Find similar

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 11/8

11:31 am-5:51 pm

1 stop6h 20m

Greenville

Sun 11/9

6:00 am-10:24 am

1 stop4h 24m

$259

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 9/25

7:30 am-12:28 pm

1 stop4h 58m

Greenville

Mon 9/29

6:19 pm-10:11 pm

1 stop3h 52m

$268

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 11/21

5:00 am-8:35 am

1 stop3h 35m

Greenville

Sun 11/23

6:40 pm-12:19 am

1 stop5h 39m

$298

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 9/12

6:30 pm-10:58 pm

1 stop4h 28m

Greenville

Mon 9/15

10:53 am-3:01 pm

1 stop4h 08m

$333

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 9/6

6:00 am-11:29 am

1 stop5h 29m

Greenville

Sat 9/6

6:30 pm-11:29 pm

1 stop4h 59m

$346

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 9/6

6:10 am-1:20 pm

2 stops7h 10m

Greenville

Sat 9/6

6:30 pm-11:29 pm

1 stop4h 59m

$351

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 9/20

10:30 am-2:16 pm

1 stop3h 46m

Greenville

Sat 9/27

10:05 am-1:54 pm

1 stop3h 49m

$355

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 9/9

6:45 am-11:56 am

1 stop5h 11m

Greenville

Sat 9/13

6:02 am-1:48 pm

1 stop7h 46m

$398

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 9/20

10:30 am-2:16 pm

1 stop3h 46m

Greenville

Sat 9/27

5:34 pm-1:54 pm

2 stops20h 20m

$461

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Mon 9/8

12:33 pm-7:23 pm

1 stop6h 50m

Greenville

Fri 9/12

6:54 pm-11:01 pm

1 stop4h 07m

$510

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Harrisburg to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Harrisburg averaging around $263.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Harrisburg. The lowest ticket price found for a Wednesday departure recently was $293. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $526. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Harrisburg to Greenville during this time can be as low as $293. Flights to Greenville are more costly at noon, with an average ticket price of $452. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Harrisburg to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Greenville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Harrisburg to Greenville (MDT to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Greenville

Direct flights	None

There are no direct flights from Harrisburg to Greenville. There are no popular flight routes from Harrisburg to Greenville.

Search flight deals

How far is Harrisburg to Greenville by plane?
Greenville is 480.4 mi away from Harrisburg. By plane, this route typically takes 3h 34m.
When did momondo last update prices for flights from Harrisburg Airport to Greenville Airport?
Prices for flights from Harrisburg Airport to Greenville Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Harrisburg Airport to Greenville Airport?
There are 3 operators available for flights from Harrisburg Airport to Greenville Airport as of August 2025.
How old do you have to be to fly from Harrisburg Airport to Greenville Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Harrisburg to Greenville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Harrisburg to Greenville is American Airlines (82% of total bookings). The next most popular airlines are United Airlines (12%) and Delta (6%).

Best airlines flying from Harrisburg to Greenville

Compare and see reviews for airlines that fly from Harrisburg to Greenville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $228	Free Cancellation	Rating 7.9 7,981 reviews	Search Delta flights
United Airlines	PriceFrom $233	Free Cancellation	Rating 7.4 8,940 reviews	Search United Airlines flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Harrisburg to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Harrisburg to Greenville with flexible booking policies on momondo?

Flights from Harrisburg to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Harrisburg to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Harrisburg to Greenville.

I’m not ready to book a flight from Harrisburg to Greenville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Harrisburg to Greenville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.