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Cheap flights from Greenville to Panama City from $230

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:42 am - 8:35 am
GSP
-
ECP
3h 53m
1 stop
Delta Logo
6:00 am - 10:35 am
ECP
-
GSP
3h 35m
1 stop
$287Delta
Tue, May 5 - Tue, May 12
Delta Logo
5:40 am - 8:30 am
GSP
-
ECP
3h 50m
1 stop
Delta Logo
7:41 am - 12:05 pm
ECP
-
GSP
3h 24m
1 stop
$297Delta
Sat, May 9 - Wed, May 13
Southwest Logo
6:25 am - 9:00 am
GSP
-
ECP
3h 35m
1 stop
Southwest Logo
11:05 am - 4:35 pm
ECP
-
GSP
4h 30m
1 stop
$307Southwest
Sat, May 2 - Sat, May 2
Southwest Logo
12:25 pm - 5:50 pm
GSP
-
ECP
6h 25m
1 stop
Southwest Logo
9:50 am - 9:55 pm
ECP
-
GSP
11h 05m
1 stop
$312Southwest
Sat, May 16 - Sat, May 23
Delta Logo
8:52 am - 12:26 pm
GSP
-
ECP
4h 34m
1 stop
Delta Logo
7:46 am - 2:01 pm
ECP
-
GSP
5h 15m
1 stop
$317Delta
Wed, Jun 24 - Wed, Jul 8
Delta Logo
7:59 pm - 11:12 pm
GSP
-
ECP
4h 13m
1 stop
Delta Logo
6:45 pm - 11:43 pm
ECP
-
GSP
3h 58m
1 stop
$327Delta
Mon, May 4 - Mon, May 11
American Airlines Logo
5:20 am - 10:03 am
GSP
-
ECP
5h 43m
1 stop
American Airlines Logo
4:40 pm - 11:57 pm
ECP
-
GSP
6h 17m
1 stop
$333American Airlines
Mon, Apr 27 - Thu, Apr 30
Delta Logo
5:44 am - 8:14 am
GSP
-
ECP
3h 30m
1 stop
Delta Logo
2:43 pm - 7:16 pm
ECP
-
GSP
3h 33m
1 stop
$337Delta
Sun, Jun 14 - Wed, Jun 17
Southwest Logo
7:05 am - 2:15 pm
GSP
-
ECP
8h 10m
2 stops
Southwest Logo
7:40 am - 12:15 pm
ECP
-
GSP
3h 35m
1 stop
$342Southwest
Thu, Jun 18 - Tue, Jun 30
Delta Logo
5:44 am - 8:14 am
GSP
-
ECP
3h 30m
1 stop
Delta Logo
7:46 am - 2:01 pm
ECP
-
GSP
5h 15m
1 stop
$347Delta
Thu, Jun 25 - Tue, Jul 7

Delta flights from Greenville to Panama City, Florida

Our best Delta deals on Greenville to Panama City, Florida flight tickets
Delta
May 5
GSP5:42 amGreenville
3h 53m
1 stop
ECP8:35 amPanama City NW Florida Beaches
May 13
ECP7:41 amPanama City NW Florida Beaches
3h 24m
1 stop
GSP12:05 pmGreenville
$287
Delta
May 9
GSP5:40 amGreenville
3h 50m
1 stop
ECP8:30 amPanama City NW Florida Beaches
May 13
ECP7:41 amPanama City NW Florida Beaches
3h 24m
1 stop
GSP12:05 pmGreenville
$297
Delta
Jun 24
GSP8:52 amGreenville
4h 34m
1 stop
ECP12:26 pmPanama City NW Florida Beaches
Jul 2
ECP9:19 amPanama City NW Florida Beaches
5h 51m
1 stop
GSP4:10 pmGreenville
$317

American Airlines flights from Greenville to Panama City, Florida

Our best American Airlines deals on Greenville to Panama City, Florida flight tickets
American Airlines
Apr 27
GSP5:20 amGreenville
5h 43m
1 stop
ECP10:03 amPanama City NW Florida Beaches
Apr 30
ECP4:40 pmPanama City NW Florida Beaches
6h 17m
1 stop
GSP11:57 pmGreenville
$333
American Airlines
May 8
GSP5:20 amGreenville
5h 43m
1 stop
ECP10:03 amPanama City NW Florida Beaches
May 9
ECP4:40 pmPanama City NW Florida Beaches
6h 17m
1 stop
GSP11:57 pmGreenville
$382
American Airlines
Apr 27
GSP5:20 amGreenville
5h 43m
1 stop
ECP10:03 amPanama City NW Florida Beaches
Apr 30
ECP4:40 pmPanama City NW Florida Beaches
6h 17m
1 stop
GSP11:57 pmGreenville
$393

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Greenville to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 5/5

5:42 am-8:35 am

1 stop3h 53m

Panama City NW Florida Beaches

Tue 5/12

6:00 am-10:35 am

1 stop3h 35m

$287

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 5/9

5:40 am-8:30 am

1 stop3h 50m

Panama City NW Florida Beaches

Wed 5/13

7:41 am-12:05 pm

1 stop3h 24m

$297

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 5/2

6:25 am-9:00 am

1 stop3h 35m

Panama City NW Florida Beaches

Sat 5/2

11:05 am-4:35 pm

1 stop4h 30m

$307

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 5/16

12:25 pm-5:50 pm

1 stop6h 25m

Panama City NW Florida Beaches

Sat 5/23

9:50 am-9:55 pm

1 stop11h 05m

$312

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 6/24

8:52 am-12:26 pm

1 stop4h 34m

Panama City NW Florida Beaches

Wed 7/8

7:46 am-2:01 pm

1 stop5h 15m

$317

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 5/4

7:59 pm-11:12 pm

1 stop4h 13m

Panama City NW Florida Beaches

Mon 5/11

6:45 pm-11:43 pm

1 stop3h 58m

$327

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 4/27

5:20 am-10:03 am

1 stop5h 43m

Panama City NW Florida Beaches

Thu 4/30

4:40 pm-11:57 pm

1 stop6h 17m

$333
Quickest round-trip

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sun 6/14

5:44 am-8:14 am

1 stop3h 30m

Panama City NW Florida Beaches

Wed 6/17

2:43 pm-7:16 pm

1 stop3h 33m

$337

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Thu 6/18

7:05 am-2:15 pm

2 stops8h 10m

Panama City NW Florida Beaches

Tue 6/30

7:40 am-12:15 pm

1 stop3h 35m

$342

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Thu 6/25

5:44 am-8:14 am

1 stop3h 30m

Panama City NW Florida Beaches

Tue 7/7

7:46 am-2:01 pm

1 stop5h 15m

$347

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Greenville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Panama City, Florida?

When to book flights from Greenville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Panama City, Florida (GSP to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama City, Florida

Fastest flight time

3h 30m

Direct flights

None
The fastest flight from Greenville to Panama City, Florida takes 3h 30m
There are no direct flights from Greenville to Panama City, Florida. There are no popular flight routes from Greenville to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Greenville to Panama City, Florida

  • How far is Greenville to Panama City NW Florida Beaches by plane?

    Panama City NW Florida Beaches is 375.7 mi away from Greenville. Flights usually cover this in 3h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Greenville Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Greenville Airport to Panama City NW Florida Beaches Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Greenville Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Greenville Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Panama City, Florida?

Best airlines flying from Greenville to Panama City, Florida

Compare and see reviews for airlines that fly from Greenville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $266Free CancellationRating
7.9
8,392 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Panama City for you.

Can I find flights from Greenville to Panama City with flexible booking policies on momondo?

Flights from Greenville to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Greenville to Panama City.

I’m not ready to book a flight from Greenville to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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