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Cheap flights from Greenville to Panama City from $134

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 9/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Panama City (GSP-ECP)

Cheap round-trip flights

Delta Logo
5:30 am - 8:44 amGSP-ECP
4h 14m1 stop
Delta Logo
6:00 am - 10:09 amECP-GSP
3h 09m1 stop
$237Delta
Find Deal
Wed, Oct 8 - Wed, Oct 15
Delta Logo
5:30 am - 8:08 amGSP-ECP
3h 38m1 stop
Delta Logo
6:00 am - 10:09 amECP-GSP
3h 09m1 stop
$242Delta
Find Deal
Sat, Oct 4 - Tue, Oct 7
Delta Logo
7:45 pm - 11:03 pmGSP-ECP
4h 18m1 stop
Delta Logo
6:54 pm - 11:52 pmECP-GSP
3h 58m1 stop
$257Delta
Find Deal
Fri, Sep 26 - Mon, Sep 29
Delta Logo
7:41 pm - 11:10 pmGSP-ECP
4h 29m1 stop
Delta Logo
6:00 am - 10:09 amECP-GSP
3h 09m1 stop
$302Delta
Find Deal
Fri, Oct 24 - Mon, Oct 27
Southwest Logo
1:50 pm - 10:35 pmGSP-ECP
9h 45m2 stops
Southwest Logo
7:20 am - 9:25 pmECP-GSP
13h 05m2 stops
$353Southwest
Find Deal
Fri, Oct 24 - Mon, Oct 27
American Airlines Logo
7:45 am - 10:33 amGSP-ECP
3h 48m1 stop
American Airlines Logo
7:15 am - 2:06 pmECP-GSP
5h 51m1 stop
$357American Airlines
Find Deal
Sun, Nov 2 - Sun, Nov 9
Southwest Logo
10:30 am - 6:35 pmGSP-ECP
9h 05m1 stop
Southwest Logo
7:20 am - 9:25 pmECP-GSP
13h 05m2 stops
$363Southwest
Find Deal
Fri, Oct 24 - Mon, Oct 27
American Airlines Logo
8:05 am - 11:16 amGSP-ECP
4h 11m1 stop
American Airlines Logo
11:58 am - 11:21 pmECP-GSP
10h 23m2 stops
$385American Airlines
Find Deal
Sat, Oct 4 - Tue, Oct 7
United Airlines Logo
4:30 pm - 2:24 pmGSP-ECP
22h 54m2 stops
United Airlines Logo
3:03 pm - 3:00 pmECP-GSP
22h 57m2 stops
$738United Airlines
Find Deal
Mon, Sep 8 - Fri, Sep 12
United Airlines Logo
2:46 pm - 4:16 pmGSP-ECP
26h 30m2 stops
United Airlines Logo
5:08 pm - 9:18 pmECP-GSP
27h 10m2 stops
$892United Airlines
Find Deal
Thu, Oct 2 - Sun, Oct 5

Delta flights from Greenville to Panama City, Florida

Our best Delta deals on Greenville to Panama City, Florida flight tickets
Delta
Oct 8
GSP5:30 amGreenville
4h 14m
1 stop
ECP8:44 amPanama City NW Florida Beaches
Oct 15
ECP6:00 amPanama City NW Florida Beaches
3h 09m
1 stop
GSP10:09 amGreenville
$237
Find similar
Delta
Oct 4
GSP5:30 amGreenville
3h 38m
1 stop
ECP8:08 amPanama City NW Florida Beaches
Oct 7
ECP6:00 amPanama City NW Florida Beaches
3h 09m
1 stop
GSP10:09 amGreenville
$242
Find similar
Delta
Sep 26
GSP7:45 pmGreenville
4h 18m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
Sep 29
ECP7:00 amPanama City NW Florida Beaches
5h 28m
1 stop
GSP1:28 pmGreenville
$257
Find similar

American Airlines flights from Greenville to Panama City, Florida

Our best American Airlines deals on Greenville to Panama City, Florida flight tickets
American Airlines
Nov 2
GSP7:45 amGreenville
3h 48m
1 stop
ECP10:33 amPanama City NW Florida Beaches
Nov 9
ECP7:15 amPanama City NW Florida Beaches
5h 51m
1 stop
GSP2:06 pmGreenville
$357
Find similar
American Airlines
Oct 4
GSP8:05 amGreenville
4h 11m
1 stop
ECP11:16 amPanama City NW Florida Beaches
Oct 7
ECP11:58 amPanama City NW Florida Beaches
10h 23m
2 stops
GSP11:21 pmGreenville
$385
Find similar
American Airlines
Sep 5
GSP12:20 pmGreenville
6h 16m
1 stop
ECP5:36 pmPanama City NW Florida Beaches
Sep 13
ECP6:06 pmPanama City NW Florida Beaches
3h 52m
1 stop
GSP10:58 pmGreenville
$393
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 26, 2025.
Use the filters below to find and compare flights from Greenville to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 10/8

5:30 am-8:44 am

1 stop4h 14m

Panama City NW Florida Beaches

Wed 10/15

6:00 am-10:09 am

1 stop3h 09m

$237

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 10/4

5:30 am-8:08 am

1 stop3h 38m

Panama City NW Florida Beaches

Tue 10/7

6:00 am-10:09 am

1 stop3h 09m

$242

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 9/26

7:45 pm-11:03 pm

1 stop4h 18m

Panama City NW Florida Beaches

Mon 9/29

6:54 pm-11:52 pm

1 stop3h 58m

$257

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 10/24

7:41 pm-11:10 pm

1 stop4h 29m

Panama City NW Florida Beaches

Mon 10/27

6:00 am-10:09 am

1 stop3h 09m

$302

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 10/24

1:50 pm-10:35 pm

2 stops9h 45m

Panama City NW Florida Beaches

Mon 10/27

7:20 am-9:25 pm

2 stops13h 05m

$353

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sun 11/2

7:45 am-10:33 am

1 stop3h 48m

Panama City NW Florida Beaches

Sun 11/9

7:15 am-2:06 pm

1 stop5h 51m

$357

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 10/24

10:30 am-6:35 pm

1 stop9h 05m

Panama City NW Florida Beaches

Mon 10/27

7:20 am-9:25 pm

2 stops13h 05m

$363

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 10/4

8:05 am-11:16 am

1 stop4h 11m

Panama City NW Florida Beaches

Tue 10/7

11:58 am-11:21 pm

2 stops10h 23m

$385

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 9/8

4:30 pm-2:24 pm

2 stops22h 54m

Panama City NW Florida Beaches

Fri 9/12

3:03 pm-3:00 pm

2 stops22h 57m

$738

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Thu 10/2

2:46 pm-4:16 pm

2 stops26h 30m

Panama City NW Florida Beaches

Sun 10/5

5:08 pm-9:18 pm

2 stops27h 10m

$892

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Greenville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Greenville is in June. Flight prices, which tend to average around $280, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from Greenville averaging around $306.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $310. On the other hand, Wednesday is the most expensive day to depart from Greenville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $437.

When to book flights from Greenville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Panama City, Florida (GSP to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama City, Florida

Direct flights

None
There are no direct flights from Greenville to Panama City, Florida. There are no popular flight routes from Greenville to Panama City, Florida.
Search flight deals

  • How far is Greenville to Panama City NW Florida Beaches by plane?

    Panama City NW Florida Beaches is 375.7 mi away from Greenville. Flights usually cover this in 3h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Greenville Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Greenville Airport to Panama City NW Florida Beaches Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Greenville Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Greenville Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Panama City, Florida?

Best airlines flying from Greenville to Panama City, Florida

Compare and see reviews for airlines that fly from Greenville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $254Free CancellationRating
7.9
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $280Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $301Free CancellationRating
8.0
4,243 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Panama City for you.

Can I find flights from Greenville to Panama City with flexible booking policies on momondo?

Flights from Greenville to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Greenville to Panama City.

I’m not ready to book a flight from Greenville to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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