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Cheap flights from Greenville to Panama City from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 3/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
10:09 am - 12:50 pm
GSP
-
ECP
3h 41m
1 stop
Delta Logo
7:41 am - 12:03 pm
ECP
-
GSP
3h 22m
1 stop
$271Delta
Tue, May 19 - Wed, May 20
Delta Logo
8:45 am - 10:44 am
GSP
-
ECP
2h 59m
1 stop
Delta Logo
1:50 pm - 8:13 pm
ECP
-
GSP
5h 23m
1 stop
$280Delta
Mon, May 18 - Wed, May 20
Southwest Logo
12:35 pm - 8:00 pm
GSP
-
ECP
8h 25m
2 stops
Southwest Logo
4:55 pm - 10:45 pm
ECP
-
GSP
4h 50m
1 stop
$285Southwest
Tue, Mar 17 - Mon, Mar 23
Delta Logo
7:59 pm - 11:04 pm
GSP
-
ECP
4h 05m
1 stop
Delta Logo
6:43 pm - 11:54 pm
ECP
-
GSP
4h 11m
1 stop
$289Delta
Mon, Mar 23 - Mon, Mar 30
Delta Logo
7:59 pm - 11:04 pm
GSP
-
ECP
4h 05m
1 stop
Delta Logo
6:00 am - 11:05 am
ECP
-
GSP
4h 05m
1 stop
$290Delta
Mon, Mar 23 - Wed, Mar 25
Southwest Logo
6:20 am - 5:30 pm
GSP
-
ECP
12h 10m
2 stops
Southwest Logo
7:20 am - 11:45 am
ECP
-
GSP
3h 25m
1 stop
$291Southwest
Wed, Mar 11 - Mon, Mar 16
Delta Logo
7:59 pm - 11:04 pm
GSP
-
ECP
4h 05m
1 stop
Delta Logo
6:43 pm - 11:54 pm
ECP
-
GSP
4h 11m
1 stop
$299Delta
Mon, Mar 23 - Thu, Mar 26
Southwest Logo
6:25 am - 9:05 am
GSP
-
ECP
3h 40m
1 stop
Southwest Logo
7:10 am - 8:55 pm
ECP
-
GSP
12h 45m
2 stops
$300Southwest
Mon, Apr 13 - Thu, Apr 16
Delta Logo
11:30 am - 2:04 pm
GSP
-
ECP
3h 34m
1 stop
Delta Logo
6:47 pm - 11:53 pm
ECP
-
GSP
4h 06m
1 stop
$304Delta
Tue, May 19 - Fri, May 22
Delta Logo
8:45 am - 10:44 am
GSP
-
ECP
2h 59m
1 stop
Delta Logo
6:47 pm - 11:53 pm
ECP
-
GSP
4h 06m
1 stop
$313Delta
Mon, May 18 - Fri, May 22

Southwest flights from Greenville to Panama City, Florida

Our best Southwest deals on Greenville to Panama City, Florida flight tickets
Southwest
Mar 17
GSP12:35 pmGreenville
8h 25m
2 stops
ECP8:00 pmPanama City NW Florida Beaches
Mar 23
ECP4:55 pmPanama City NW Florida Beaches
4h 50m
1 stop
GSP10:45 pmGreenville
$285
Southwest
Mar 11
GSP6:20 amGreenville
12h 10m
2 stops
ECP5:30 pmPanama City NW Florida Beaches
Mar 16
ECP7:20 amPanama City NW Florida Beaches
3h 25m
1 stop
GSP11:45 amGreenville
$291
Southwest
Apr 13
GSP6:25 amGreenville
3h 40m
1 stop
ECP9:05 amPanama City NW Florida Beaches
Apr 16
ECP7:10 amPanama City NW Florida Beaches
12h 45m
2 stops
GSP8:55 pmGreenville
$300

Delta flights from Greenville to Panama City, Florida

Our best Delta deals on Greenville to Panama City, Florida flight tickets
Delta
May 19
GSP10:09 amGreenville
3h 41m
1 stop
ECP12:50 pmPanama City NW Florida Beaches
May 20
ECP7:41 amPanama City NW Florida Beaches
3h 22m
1 stop
GSP12:03 pmGreenville
$271
Delta
May 18
GSP8:45 amGreenville
2h 59m
1 stop
ECP10:44 amPanama City NW Florida Beaches
May 20
ECP1:50 pmPanama City NW Florida Beaches
5h 23m
1 stop
GSP8:13 pmGreenville
$280
Delta
Mar 23
GSP7:59 pmGreenville
4h 05m
1 stop
ECP11:04 pmPanama City NW Florida Beaches
Mar 30
ECP6:43 pmPanama City NW Florida Beaches
4h 11m
1 stop
GSP11:54 pmGreenville
$289

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Greenville to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 5/19

10:09 am-12:50 pm

1 stop3h 41m

Panama City NW Florida Beaches

Wed 5/20

7:41 am-12:03 pm

1 stop3h 22m

$271

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 5/18

8:45 am-10:44 am

1 stop2h 59m

Panama City NW Florida Beaches

Wed 5/20

1:50 pm-8:13 pm

1 stop5h 23m

$280

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 3/17

12:35 pm-8:00 pm

2 stops8h 25m

Panama City NW Florida Beaches

Mon 3/23

4:55 pm-10:45 pm

1 stop4h 50m

$285

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 3/23

7:59 pm-11:04 pm

1 stop4h 05m

Panama City NW Florida Beaches

Mon 3/30

6:43 pm-11:54 pm

1 stop4h 11m

$289

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 3/23

7:59 pm-11:04 pm

1 stop4h 05m

Panama City NW Florida Beaches

Wed 3/25

6:00 am-11:05 am

1 stop4h 05m

$290

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 3/11

6:20 am-5:30 pm

2 stops12h 10m

Panama City NW Florida Beaches

Mon 3/16

7:20 am-11:45 am

1 stop3h 25m

$291

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 3/23

7:59 pm-11:04 pm

1 stop4h 05m

Panama City NW Florida Beaches

Thu 3/26

6:43 pm-11:54 pm

1 stop4h 11m

$299

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 4/13

6:25 am-9:05 am

1 stop3h 40m

Panama City NW Florida Beaches

Thu 4/16

7:10 am-8:55 pm

2 stops12h 45m

$300

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 5/19

11:30 am-2:04 pm

1 stop3h 34m

Panama City NW Florida Beaches

Fri 5/22

6:47 pm-11:53 pm

1 stop4h 06m

$304

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 5/18

8:45 am-10:44 am

1 stop2h 59m

Panama City NW Florida Beaches

Fri 5/22

6:47 pm-11:53 pm

1 stop4h 06m

$313

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Greenville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Greenville is in December. Flight prices, which tend to average around $278, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Panama City, Florida, with average flight prices from Greenville averaging around $280.

When to book flights from Greenville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Panama City, Florida (GSP to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama City, Florida

Fastest flight time

2h 52m

Direct flights

None
The fastest flight from Greenville to Panama City, Florida takes 2h 52m
There are no direct flights from Greenville to Panama City, Florida. There are no popular flight routes from Greenville to Panama City, Florida.
Search flight deals

  • How far is Greenville to Panama City NW Florida Beaches by plane?

    Panama City NW Florida Beaches is 375.7 mi away from Greenville. Flights usually cover this in 2h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Greenville Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Greenville Airport to Panama City NW Florida Beaches Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Greenville Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Greenville Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Panama City, Florida?

Best airlines flying from Greenville to Panama City, Florida

Compare and see reviews for airlines that fly from Greenville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $254Free CancellationRating
7.9
8,177 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Panama City for you.

Can I find flights from Greenville to Panama City with flexible booking policies on momondo?

Flights from Greenville to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Greenville to Panama City.

I’m not ready to book a flight from Greenville to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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