Cheap flights from Fort Myers to Indianapolis from $86

In general, September is the cheapest month to fly from Fort Myers to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $196. If you are unable to visit Indianapolis during the month of September, then departing from Fort Myers during the month January is also very affordable. Most momondo users find prices during this month for around $249.

Our data shows that Wednesday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $320. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Friday is $446.

Flying to Indianapolis from Fort Myers in the evening is the least expensive time of day to depart. momondo users have found prices as low as $318 when looking at flights departing in the evening. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $417 on average. Flights to Indianapolis from Fort Myers in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Fort Myers SW Florida Intl to Indianapolis for the best Fort Myers SW Florida Intl - Indianapolis flight prices

You are more likely to see cheaper flights to Indianapolis from Fort Myers when booking weeks ahead of your departure date. In general, you can expect to find flights to Indianapolis for around $323 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Indianapolis from Fort Myers for as low as $275 on momondo.

There is only 1 cabin class available to choose from on Fort Myers SW Florida Intl to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 21% on your flight if you consider stops on a Fort Myers to Indianapolis flight.

As of March 2026, prices for Fort Myers to Indianapolis flights are approximately 173% more expensive when compared to flights at the same time last year.

Southwest, Delta, and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Indianapolis

Allegiant Air, Frontier and Delta are the top three most popular airlines that fly to Indianapolis from Fort Myers according to our data. Allegiant Air is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Indianapolis. Keep in mind that there are 5 different airlines that fly to Indianapolis on a routine basis, so you have a few additional options to choose from.

Atlanta (ATL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Charlotte (CLT) offer the lowest average round-trip price of $186.

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 32m.

Charlotte (CLT) has the shortest average layover time for this route: 0h 45m.

The number of flights available between Fort Myers and Indianapolis is 2 per day as of March 2026. The most frequent departure time is 5:00AM, with 33% of daily flights leaving in the afternoon.

As of March 2026, 18 flights take off from Fort Myers and land in Indianapolis each week. The most common flight departure day for this route is Mon, with 28% of weekly flights taking off on this day.