Cheap flights from Fort Myers to Buffalo from $119

If you aren’t able to travel during the month of May, then book flights to Buffalo from Fort Myers during June instead. Flights to Buffalo in June, while not as cheap as those in May, still average around $266.

Our data shows that Friday is the least expensive day to fly to Buffalo. Tickets to fly out on this day can be as low as $232. Flights from Fort Myers to Buffalo on a Saturday will generally be more expensive and average around $547. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

In the afternoon is the cheapest time of day to fly from Fort Myers to Buffalo when you can find flight prices for as low as $278. Flying to Buffalo in the afternoon is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Buffalo, so prices are often more expensive at around $427 per ticket.

Fly from Fort Myers SW Florida Intl to Buffalo for the best Fort Myers SW Florida Intl - Buffalo flight prices

You are more likely to see cheaper flights to Buffalo from Fort Myers when booking weeks ahead of your departure date. In general, you can expect to find flights to Buffalo for around $318 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Buffalo from Fort Myers for as low as $242 on momondo.

There are 2 cabin classes available to choose from on Fort Myers to Buffalo flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 2% on your flight if you consider stops on a Fort Myers to Buffalo flight.

As of November 2026, prices for Fort Myers to Buffalo flights are approximately 1% cheaper when compared to flights at the same time last year.

Delta and United Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Buffalo

Southwest, Delta and Allegiant Air are the top three most popular airlines that fly to Buffalo from Fort Myers according to our data. Southwest is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Buffalo. Keep in mind that there are 9 different airlines that fly to Buffalo on a routine basis, so you have a few additional options to choose from.

Atlanta (ATL) was the most common stop: 60% of momondo users choosing 1-stop flights on this route connected there.

Flights via Detroit (DTW) offer the lowest average round-trip price of $350.

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 6h 12m.

Detroit (DTW) has the shortest average layover time for this route: 1h 42m.