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Cheap flights from Des Moines to Puerto Rico from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Puerto Rico departing on 1/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Puerto Rico

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:58 pm - 12:32 pm
DSM
-
SJU
19h 34m1 stop
Multiple Airlines Logo
2:59 am - 10:19 am
SJU
-
DSM
33h 20m2 stops
$299Multiple Airlines
Sun, Jan 18 - Sat, Jan 24
Multiple Airlines Logo
2:08 pm - 1:24 am
DSM
-
SJU
33h 16m2 stops
Multiple Airlines Logo
4:31 pm - 11:12 pm
SJU
-
DSM
8h 41m1 stop
$326Multiple Airlines
Mon, Feb 9 - Thu, Feb 12
Multiple Airlines Logo
3:32 pm - 3:31 pm
DSM
-
SJU
21h 59m1 stop
Multiple Airlines Logo
6:00 am - 6:32 pm
SJU
-
DSM
38h 32m2 stops
$337Multiple Airlines
Sun, Feb 15 - Sun, Feb 22
American Airlines Logo
6:00 am - 8:50 pm
DSM
-
SJU
12h 50m2 stops
American Airlines Logo
12:45 pm - 10:04 pm
SJU
-
DSM
11h 19m2 stops
$394American Airlines
Thu, Feb 5 - Thu, Feb 12
Delta Logo
6:24 am - 8:58 pm
DSM
-
SJU
12h 34m2 stops
Delta Logo
6:15 am - 4:27 pm
SJU
-
DSM
12h 12m1 stop
$395Delta
Tue, Feb 10 - Tue, Feb 24
Frontier Logo
6:56 pm - 10:45 pm
DSM
-
SJU
25h 49m1 stop
Frontier Logo
11:07 am - 10:05 am
SJU
-
DSM
23h 58m1 stop
$404Frontier
Sat, Mar 7 - Sun, Mar 15
American Airlines Logo
6:00 am - 8:50 pm
DSM
-
SJU
12h 50m2 stops
American Airlines Logo
8:20 am - 4:24 pm
SJU
-
DSM
10h 04m2 stops
$406American Airlines
Sat, Jan 31 - Fri, Feb 6
Delta Logo
11:46 am - 11:58 pm
DSM
-
SJU
10h 12m1 stop
Delta Logo
6:15 am - 4:33 pm
SJU
-
DSM
11h 18m1 stop
$417Delta
Thu, Feb 26 - Sun, Mar 8
United Airlines Logo
8:00 am - 11:57 pm
DSM
-
BQN
13h 57m2 stops
United Airlines Logo
1:09 am - 10:55 am
BQN
-
DSM
11h 46m2 stops
$485United Airlines
Mon, Jan 26 - Wed, Jan 28
United Airlines Logo
8:00 am - 11:09 pm
DSM
-
BQN
14h 09m2 stops
United Airlines Logo
12:15 am - 10:41 am
BQN
-
DSM
11h 26m2 stops
$660United Airlines
Mon, May 11 - Tue, May 12

Frontier flights from Des Moines to Puerto Rico

Our best Frontier deals on Des Moines to Puerto Rico flight tickets
Frontier
Mar 7
DSM6:56 pmDes Moines
25h 49m
1 stop
SJU10:45 pmSan Juan Luis Munoz Marin Intl
Mar 15
SJU11:07 amSan Juan Luis Munoz Marin Intl
23h 58m
1 stop
DSM10:05 amDes Moines
$404
Find similar
Frontier
Dec 30
DSM11:14 amDes Moines
20h 09m
1 stop
SJU9:23 amSan Juan Luis Munoz Marin Intl
Jan 3
SJU9:58 pmSan Juan Luis Munoz Marin Intl
14h 14m
1 stop
DSM10:12 amDes Moines
$706
Find similar
Frontier
Dec 28
DSM10:17 amDes Moines
21h 06m
1 stop
SJU9:23 amSan Juan Luis Munoz Marin Intl
Jan 3
SJU3:55 amSan Juan Luis Munoz Marin Intl
8h 17m
1 stop
DSM10:12 amDes Moines
$731
Find similar

United Airlines flights from Des Moines to Puerto Rico

Our best United Airlines deals on Des Moines to Puerto Rico flight tickets
United Airlines
Jun 10
DSM11:30 amDes Moines
8h 04m
1 stop
SJU8:34 pmSan Juan Luis Munoz Marin Intl
Jun 16
SJU1:05 amSan Juan Luis Munoz Marin Intl
14h 06m
2 stops
DSM2:11 pmDes Moines
$435
Find similar
United Airlines
Jan 18
DSM3:35 pmDes Moines
12h 36m
2 stops
SJU6:11 amSan Juan Luis Munoz Marin Intl
Jan 24
SJU2:05 amSan Juan Luis Munoz Marin Intl
14h 28m
2 stops
DSM2:33 pmDes Moines
$456
Find similar
United Airlines
Jun 10
DSM6:15 amDes Moines
13h 23m
2 stops
SJU8:38 pmSan Juan Luis Munoz Marin Intl
Jun 16
SJU1:05 amSan Juan Luis Munoz Marin Intl
10h 15m
2 stops
DSM10:20 amDes Moines
$484
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Puerto Rico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Des Moines to Puerto Rico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Sun 1/18

2:58 pm-12:32 pm

1 stop19h 34m

San Juan Luis Munoz Marin Intl

Sat 1/24

2:59 am-10:19 am

2 stops33h 20m

$299

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Mon 2/9

2:08 pm-1:24 am

2 stops33h 16m

San Juan Luis Munoz Marin Intl

Thu 2/12

4:31 pm-11:12 pm

1 stop8h 41m

$326

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Sun 2/15

3:32 pm-3:31 pm

1 stop21h 59m

San Juan Luis Munoz Marin Intl

Sun 2/22

6:00 am-6:32 pm

2 stops38h 32m

$337

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Thu 2/5

6:00 am-8:50 pm

2 stops12h 50m

San Juan Luis Munoz Marin Intl

Thu 2/12

12:45 pm-10:04 pm

2 stops11h 19m

$394

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Tue 2/10

6:24 am-8:58 pm

2 stops12h 34m

San Juan Luis Munoz Marin Intl

Tue 2/24

6:15 am-4:27 pm

1 stop12h 12m

$395

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Sat 3/7

6:56 pm-10:45 pm

1 stop25h 49m

San Juan Luis Munoz Marin Intl

Sun 3/15

11:07 am-10:05 am

1 stop23h 58m

$404

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Sat 1/31

6:00 am-8:50 pm

2 stops12h 50m

San Juan Luis Munoz Marin Intl

Fri 2/6

8:20 am-4:24 pm

2 stops10h 04m

$406

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Thu 2/26

11:46 am-11:58 pm

1 stop10h 12m

San Juan Luis Munoz Marin Intl

Sun 3/8

6:15 am-4:33 pm

1 stop11h 18m

$417

Des MoinesAguadilla

DSM - BQN

DSMBQN

Des Moines

Mon 1/26

8:00 am-11:57 pm

2 stops13h 57m

Aguadilla Borinquen

Wed 1/28

1:09 am-10:55 am

2 stops11h 46m

$485

Des MoinesAguadilla

DSM - BQN

DSMBQN

Des Moines

Mon 5/11

8:00 am-11:09 pm

2 stops14h 09m

Aguadilla Borinquen

Tue 5/12

12:15 am-10:41 am

2 stops11h 26m

$660

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Puerto Rico from

How to get the cheapest flight ticket from Des Moines to Puerto Rico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Puerto Rico?

If you don’t want to visit Puerto Rico in May, then you should wait until October to fly from Des Moines, when ticket prices are also cheap, with an average price of $477.

What is the cheapest day to depart on your flight to Puerto Rico?

On average, the least expensive day to fly to Puerto Rico from Des Moines is on a Monday. momondo users have found tickets for Monday departures for as low as $426. However, this price may fluctuate depending on the airline, the season, and holidays. The most expensive day to fly to Puerto Rico is Friday, with ticket prices averaging around $604.

What is the cheapest time of day to depart on your flight to Puerto Rico?

Our most recent data shows that the best time of day to fly to Puerto Rico is in the afternoon. Flights from Des Moines to Puerto Rico during this time can be as low as $406. In contrast, the most expensive time of day to depart to Puerto Rico is at noon when prices are around $531.

How far in advance should I book a flight to Puerto Rico?

You are more likely to see cheaper flights to Puerto Rico from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Puerto Rico for around $555 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Puerto Rico from Des Moines for as low as $374 on momondo.

Can stopping save me money on Des Moines to Puerto Rico flights?

You could potentially save up to 13% on your flight if you consider stops on a Des Moines to Puerto Rico flight.

Cheap Des Moines to Puerto Rico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Puerto Rico

Fastest flight time

6h 52m

Direct flights

None
The fastest flight from Des Moines to Puerto Rico takes 6h 52m
There are no direct flights from Des Moines to Puerto Rico. There are no popular flight routes from Des Moines to Puerto Rico.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Puerto Rico?

    Prices for flights from Des Moines Airport to Puerto Rico were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Puerto Rico?

  • How old do you have to be to fly from Des Moines Airport to Puerto Rico?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Puerto Rico.

  • What documentation or ID do you need to fly to Puerto Rico?

    The travel and health documents required for your trip to Puerto Rico can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Puerto Rico. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Puerto Rico

Compare and see reviews for airlines that fly from Des Moines to Puerto Rico with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.8
3,075 reviews
Search Frontier flights
DeltaPriceFrom $357Free CancellationRating
7.9
8,014 reviews
Search Delta flights
American AirlinesPriceFrom $364Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $419Free CancellationRating
7.4
9,105 reviews
Search United Airlines flights
SouthwestPriceFrom $515Free CancellationRating
8.0
4,253 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Puerto Rico?

It is quick and easy to find Des Moines to Puerto Rico flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Puerto Rico that suits you.

Can I find flights from Des Moines to Puerto Rico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Puerto Rico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Puerto Rico?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Puerto Rico.

I’m not ready to book a flight from Des Moines to Puerto Rico right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Puerto Rico flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Puerto Rico trip

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Find better results for your trip to Puerto Rico

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