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Cheap flights from Des Moines to Puerto Rico from $273

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Puerto Rico departing on 12/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Puerto Rico

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:56 pm - 12:32 pmDSM-SJU
19h 36m1 stop
Multiple Airlines Logo
7:00 am - 7:03 pmSJU-DSM
38h 03m2 stops
$304Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
2:56 pm - 12:32 pmDSM-SJU
19h 36m1 stop
Multiple Airlines Logo
7:00 am - 7:03 pmSJU-DSM
38h 03m2 stops
$339Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Delta Logo
6:29 am - 11:44 pmDSM-SJU
15h 15m2 stops
Delta Logo
7:00 am - 5:08 pmSJU-DSM
12h 08m2 stops
$365Delta
Find Deal
Tue, Jan 20 - Thu, Jan 29
American Airlines Logo
6:52 pm - 5:00 amDSM-SJU
8h 08m1 stop
American Airlines Logo
1:58 pm - 11:08 pmSJU-DSM
11h 10m1 stop
$380American Airlines
Find Deal
Mon, Jan 5 - Wed, Jan 14
Delta Logo
1:03 pm - 11:44 pmDSM-SJU
8h 41m1 stop
Delta Logo
3:20 pm - 8:54 pmSJU-DSM
7h 34m1 stop
$390Delta
Find Deal
Sat, Jan 24 - Wed, Jan 28
American Airlines Logo
5:50 pm - 4:00 amDSM-SJU
9h 10m1 stop
American Airlines Logo
11:45 am - 9:39 pmSJU-DSM
10h 54m2 stops
$395American Airlines
Find Deal
Tue, Apr 14 - Tue, Apr 28
United Airlines Logo
3:15 pm - 11:54 pmDSM-SJU
7h 39m1 stop
United Airlines Logo
1:05 am - 10:20 amSJU-DSM
10h 15m2 stops
$401United Airlines
Find Deal
Tue, Apr 14 - Mon, Apr 27
United Airlines Logo
8:00 am - 10:22 pmDSM-SJU
12h 22m2 stops
United Airlines Logo
2:05 am - 2:33 pmSJU-DSM
14h 28m2 stops
$413United Airlines
Find Deal
Fri, Jan 23 - Wed, Jan 28
Southwest Logo
6:30 pm - 9:10 amDSM-SJU
13h 40m2 stops
Southwest Logo
8:40 pm - 11:25 amSJU-DSM
15h 45m2 stops
$420Southwest
Find Deal
Wed, Apr 22 - Mon, Apr 27
Southwest Logo
7:10 pm - 8:55 amDSM-SJU
12h 45m2 stops
Southwest Logo
6:50 am - 9:55 pmSJU-DSM
16h 05m2 stops
$451Southwest
Find Deal
Fri, Apr 10 - Mon, Apr 20

American Airlines flights from Des Moines to Puerto Rico

Our best American Airlines deals on Des Moines to Puerto Rico flight tickets
American Airlines
Jan 5
DSM6:52 pmDes Moines
8h 08m
1 stop
SJU5:00 amSan Juan Luis Munoz Marin Intl
Jan 14
SJU1:58 pmSan Juan Luis Munoz Marin Intl
11h 10m
1 stop
DSM11:08 pmDes Moines
$380
Find similar
American Airlines
Apr 14
DSM5:50 pmDes Moines
9h 10m
1 stop
SJU4:00 amSan Juan Luis Munoz Marin Intl
Apr 28
SJU11:45 amSan Juan Luis Munoz Marin Intl
10h 54m
2 stops
DSM9:39 pmDes Moines
$395
Find similar
American Airlines
Jan 4
DSM6:26 pmDes Moines
15h 13m
1 stop
SJU11:39 amSan Juan Luis Munoz Marin Intl
Jan 17
SJU6:00 amSan Juan Luis Munoz Marin Intl
13h 06m
2 stops
DSM5:06 pmDes Moines
$405
Find similar

Delta flights from Des Moines to Puerto Rico

Our best Delta deals on Des Moines to Puerto Rico flight tickets
Delta
Jan 20
DSM6:29 amDes Moines
15h 15m
2 stops
SJU11:44 pmSan Juan Luis Munoz Marin Intl
Jan 29
SJU7:00 amSan Juan Luis Munoz Marin Intl
12h 08m
2 stops
DSM5:08 pmDes Moines
$365
Find similar
Delta
Jan 24
DSM1:03 pmDes Moines
8h 41m
1 stop
SJU11:44 pmSan Juan Luis Munoz Marin Intl
Jan 28
SJU3:20 pmSan Juan Luis Munoz Marin Intl
7h 34m
1 stop
DSM8:54 pmDes Moines
$390
Find similar
Delta
Nov 16
DSM5:35 amDes Moines
9h 51m
1 stop
SJU5:26 pmSan Juan Luis Munoz Marin Intl
Nov 19
SJU3:20 pmSan Juan Luis Munoz Marin Intl
7h 27m
1 stop
DSM8:47 pmDes Moines
$417
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Puerto Rico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Des Moines to Puerto Rico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Thu 12/4

2:56 pm-12:32 pm

1 stop19h 36m

San Juan Luis Munoz Marin Intl

Thu 12/11

7:00 am-7:03 pm

2 stops38h 03m

$304

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Thu 12/4

2:56 pm-12:32 pm

1 stop19h 36m

San Juan Luis Munoz Marin Intl

Thu 12/11

7:00 am-7:03 pm

2 stops38h 03m

$339

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Tue 1/20

6:29 am-11:44 pm

2 stops15h 15m

San Juan Luis Munoz Marin Intl

Thu 1/29

7:00 am-5:08 pm

2 stops12h 08m

$365

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Mon 1/5

6:52 pm-5:00 am

1 stop8h 08m

San Juan Luis Munoz Marin Intl

Wed 1/14

1:58 pm-11:08 pm

1 stop11h 10m

$380

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Sat 1/24

1:03 pm-11:44 pm

1 stop8h 41m

San Juan Luis Munoz Marin Intl

Wed 1/28

3:20 pm-8:54 pm

1 stop7h 34m

$390

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Tue 4/14

5:50 pm-4:00 am

1 stop9h 10m

San Juan Luis Munoz Marin Intl

Tue 4/28

11:45 am-9:39 pm

2 stops10h 54m

$395

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Tue 4/14

3:15 pm-11:54 pm

1 stop7h 39m

San Juan Luis Munoz Marin Intl

Mon 4/27

1:05 am-10:20 am

2 stops10h 15m

$401

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Fri 1/23

8:00 am-10:22 pm

2 stops12h 22m

San Juan Luis Munoz Marin Intl

Wed 1/28

2:05 am-2:33 pm

2 stops14h 28m

$413

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Wed 4/22

6:30 pm-9:10 am

2 stops13h 40m

San Juan Luis Munoz Marin Intl

Mon 4/27

8:40 pm-11:25 am

2 stops15h 45m

$420

Des MoinesSan Juan

DSM - SJU

DSMSJU

Des Moines

Fri 4/10

7:10 pm-8:55 am

2 stops12h 45m

San Juan Luis Munoz Marin Intl

Mon 4/20

6:50 am-9:55 pm

2 stops16h 05m

$451

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Puerto Rico from

How to get the cheapest flight ticket from Des Moines to Puerto Rico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Puerto Rico?

If you don’t want to visit Puerto Rico in April, then you should wait until May to fly from Des Moines, when ticket prices are also cheap, with an average price of $450.

What is the cheapest day to depart on your flight to Puerto Rico?

On average, the least expensive day to fly to Puerto Rico from Des Moines is on a Monday. momondo users have found tickets for Monday departures for as low as $426. However, this price may fluctuate depending on the airline, the season, and holidays. The most expensive day to fly to Puerto Rico is Friday, with ticket prices averaging around $604.

What is the cheapest time of day to depart on your flight to Puerto Rico?

Our most recent data shows that the best time of day to fly to Puerto Rico is in the afternoon. Flights from Des Moines to Puerto Rico during this time can be as low as $406. In contrast, the most expensive time of day to depart to Puerto Rico is at noon when prices are around $531.

How far in advance should I book a flight to Puerto Rico?

You are more likely to see cheaper flights to Puerto Rico from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Puerto Rico for around $532 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Puerto Rico from Des Moines for as low as $388 on momondo.

Cheap Des Moines to Puerto Rico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Puerto Rico

Direct flights

None
There are no direct flights from Des Moines to Puerto Rico. There are no popular flight routes from Des Moines to Puerto Rico.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Puerto Rico?

    Prices for flights from Des Moines Airport to Puerto Rico were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Puerto Rico?

  • How old do you have to be to fly from Des Moines Airport to Puerto Rico?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Puerto Rico.

  • What documentation or ID do you need to fly to Puerto Rico?

    The travel and health documents required for your trip to Puerto Rico can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Puerto Rico. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Puerto Rico

Compare and see reviews for airlines that fly from Des Moines to Puerto Rico with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $150Free CancellationRating
5.8
3,115 reviews
Search Frontier flights
American AirlinesPriceFrom $347Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
DeltaPriceFrom $357Free CancellationRating
7.9
8,001 reviews
Search Delta flights
United AirlinesPriceFrom $419Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
SouthwestPriceFrom $515Free CancellationRating
8.0
4,241 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Puerto Rico?

It is quick and easy to find Des Moines to Puerto Rico flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Puerto Rico that suits you.

Can I find flights from Des Moines to Puerto Rico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Puerto Rico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Puerto Rico?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Puerto Rico.

I’m not ready to book a flight from Des Moines to Puerto Rico right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Puerto Rico flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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