What is the cheapest airline that flies from Des Moines to Václav Havel Prague?

British Airways, Lufthansa, and Air Canada are the most popular carriers operating from Des Moines to Václav Havel Prague

When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?

As of October 2025, there is 1 operator available to choose from for flights from Des Moines Airport to Václav Havel Prague Airport.

How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.

What documentation or ID do you need to fly to Václav Havel Prague Airport?

The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$437 Cheap Flights from Des Moines to Prague in 2025/26

Q: What is the typical price of a round-trip flight between Des Moines and Prague?

Prices are currently low for flights on this route. Typical prices usually range from $715 to $748. The lowest price recently found on this route was $526.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Des Moines to Prague

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:50 pm - 10:25 pmDSM-PRG

20h 35m2 stops

6:15 am - 5:24 pmPRG-DSM

18h 09m2 stops

$526Multiple Airlines

Find Deal

Tue, Dec 2 - Tue, Dec 9

6:50 pm - 10:25 pmDSM-PRG

20h 35m2 stops

6:15 am - 9:37 pmPRG-DSM

22h 22m2 stops

$528Lufthansa

Find Deal

Tue, Dec 2 - Tue, Dec 9

2:16 pm - 9:45 amDSM-PRG

36h 29m2 stops

3:00 pm - 10:34 pmPRG-DSM

38h 34m2 stops

$538Scandinavian Airlines

Find Deal

Fri, Dec 5 - Fri, Dec 12

2:16 pm - 9:45 amDSM-PRG

36h 29m2 stops

3:00 pm - 10:34 pmPRG-DSM

38h 34m2 stops

$539Scandinavian Airlines

Find Deal

Fri, Dec 5 - Fri, Dec 12

6:50 pm - 10:25 pmDSM-PRG

20h 35m2 stops

7:25 am - 9:37 pmPRG-DSM

21h 12m2 stops

$545Lufthansa

Find Deal

Tue, Dec 2 - Tue, Dec 9

6:33 pm - 9:05 amDSM-PRG

55h 32m2 stops

6:30 am - 4:16 pmPRG-DSM

16h 46m2 stops

$554Air France

Find Deal

Wed, Dec 3 - Wed, Dec 10

6:50 pm - 10:25 pmDSM-PRG

20h 35m2 stops

7:25 am - 9:37 pmPRG-DSM

21h 12m2 stops

$555United Airlines

Find Deal

Tue, Dec 2 - Tue, Dec 9

6:50 pm - 10:25 pmDSM-PRG

20h 35m2 stops

7:35 am - 9:37 pmPRG-DSM

21h 02m2 stops

$568United Airlines

Find Deal

Thu, Dec 4 - Thu, Dec 11

11:35 am - 2:05 pmDSM-PRG

19h 30m3 stops

7:35 am - 9:37 pmPRG-DSM

21h 02m3 stops

$835Air Canada

Find Deal

Fri, Dec 5 - Fri, Dec 12

11:35 am - 2:05 pmDSM-PRG

19h 30m3 stops

7:35 am - 9:37 pmPRG-DSM

21h 02m3 stops

$839Air Canada

Find Deal

Fri, Dec 5 - Fri, Dec 12

United Airlines flights from Des Moines to Prague

Our best United Airlines deals on Des Moines to Prague flight tickets

United Airlines

Dec 2

DSM6:50 pmDes Moines

20h 35m

2 stops

PRG10:25 pmVáclav Havel Prague

Dec 9

PRG7:25 amVáclav Havel Prague

21h 12m

2 stops

DSM9:37 pmDes Moines

$555

Find similar

United Airlines

Dec 4

DSM6:50 pmDes Moines

20h 35m

2 stops

PRG10:25 pmVáclav Havel Prague

Dec 11

PRG7:35 amVáclav Havel Prague

21h 02m

2 stops

DSM9:37 pmDes Moines

$568

Find similar

United Airlines

Mar 27

DSM3:15 pmDes Moines

16h 40m

2 stops

PRG1:55 pmVáclav Havel Prague

Mar 31

PRG6:00 amVáclav Havel Prague

18h 33m

2 stops

DSM5:33 pmDes Moines

$657

Find similar

Lufthansa flights from Des Moines to Prague

Our best Lufthansa deals on Des Moines to Prague flight tickets

Lufthansa

Dec 2

DSM6:50 pmDes Moines

20h 35m

2 stops

PRG10:25 pmVáclav Havel Prague

Dec 9

PRG6:15 amVáclav Havel Prague

22h 22m

2 stops

DSM9:37 pmDes Moines

$528

Find similar

Lufthansa

Dec 2

DSM6:50 pmDes Moines

20h 35m

2 stops

PRG10:25 pmVáclav Havel Prague

Dec 9

PRG7:25 amVáclav Havel Prague

21h 12m

2 stops

DSM9:37 pmDes Moines

$545

Find similar

Lufthansa

Dec 4

DSM6:50 pmDes Moines

20h 35m

2 stops

PRG10:25 pmVáclav Havel Prague

Dec 11

PRG7:35 amVáclav Havel Prague

21h 02m

2 stops

DSM9:37 pmDes Moines

$558

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 12/2

6:50 pm-10:25 pm

2 stops20h 35m

Václav Havel Prague

Tue 12/9

6:15 am-5:24 pm

2 stops18h 09m

$526

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 12/2

6:50 pm-10:25 pm

2 stops20h 35m

Václav Havel Prague

Tue 12/9

6:15 am-9:37 pm

2 stops22h 22m

$528

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 12/5

2:16 pm-9:45 am

2 stops36h 29m

Václav Havel Prague

Fri 12/12

3:00 pm-10:34 pm

2 stops38h 34m

$538

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 12/5

2:16 pm-9:45 am

2 stops36h 29m

Václav Havel Prague

Fri 12/12

3:00 pm-10:34 pm

2 stops38h 34m

$539

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 12/2

6:50 pm-10:25 pm

2 stops20h 35m

Václav Havel Prague

Tue 12/9

7:25 am-9:37 pm

2 stops21h 12m

$545

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 12/3

6:33 pm-9:05 am

2 stops55h 32m

Václav Havel Prague

Wed 12/10

6:30 am-4:16 pm

2 stops16h 46m

$554

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 12/2

6:50 pm-10:25 pm

2 stops20h 35m

Václav Havel Prague

Tue 12/9

7:25 am-9:37 pm

2 stops21h 12m

$555

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 12/4

6:50 pm-10:25 pm

2 stops20h 35m

Václav Havel Prague

Thu 12/11

7:35 am-9:37 pm

2 stops21h 02m

$568

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 12/5

11:35 am-2:05 pm

3 stops19h 30m

Václav Havel Prague

Fri 12/12

7:35 am-9:37 pm

3 stops21h 02m

$835

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 12/5

11:35 am-2:05 pm

3 stops19h 30m

Václav Havel Prague

Fri 12/12

7:35 am-9:37 pm

3 stops21h 02m

$839

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Des Moines and Prague?

What is the cheapest day to depart on your flight to Prague?

The cheapest day to depart from Des Moines to Prague is on a Tuesday. Travelers who choose to depart for Prague on a Tuesday will often find tickets for as low as $816. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Prague for around $1,811.

What is the cheapest time of day to depart on your flight to Prague?

According to our data, the cheapest time of day to fly to Prague is in the afternoon. momondo users have found flights departing from Des Moines to Prague in the afternoon for as low as $1,080. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $1,157. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Prague flight.

When to book flights from Des Moines to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Prague according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Direct flights	None

There are no direct flights from Des Moines to Prague. There are no popular flight routes from Des Moines to Prague.

Search flight deals

How far is Des Moines to Václav Havel Prague by plane?
A flight from Des Moines to Václav Havel Prague will travel around 4755.3 mi. Flights usually cover this in 16h 02m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?
Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?
As of October 2025, there is 1 operator available to choose from for flights from Des Moines Airport to Václav Havel Prague Airport.
How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.
What documentation or ID do you need to fly to Václav Havel Prague Airport?
The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Des Moines to Prague?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Prague is United Airlines (100% of total bookings).

Best airlines flying from Des Moines to Prague

Compare and see reviews for airlines that fly from Des Moines to Prague with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $597	Free Cancellation	Rating 7.4 8,988 reviews		Search United Airlines flights

Český Krumlov

Pilsen

Liberec

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Prague from Des Moines.

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

momondo does allow users to show only those flights to Prague from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Prague?

momondo provides multiple filters to help you find the best flight to Prague from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Prague from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Thu 11/20

Thu 11/27

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Cheap flights from Des Moines to Prague from $437

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Prague departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Des Moines to Prague

Cheap round-trip flights

Cheap one-way flights

United Airlines flights from Des Moines to Prague

Our best United Airlines deals on Des Moines to Prague flight tickets

Lufthansa flights from Des Moines to Prague

Our best Lufthansa deals on Des Moines to Prague flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Prague that are best for you.

See travel insights to Prague from

How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Prague?

What is the cheapest day to depart on your flight to Prague?

What is the cheapest time of day to depart on your flight to Prague?

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Prague flight.

What is the cheapest airline that flies from Des Moines to Václav Havel Prague?

British Airways, Lufthansa, and Air Canada are the most popular carriers operating from Des Moines to Václav Havel Prague

When to book flights from Des Moines to Prague

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Direct flights

How far is Des Moines to Václav Havel Prague by plane?

When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?

How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

What documentation or ID do you need to fly to Václav Havel Prague Airport?

What is the most popular airline from Des Moines to Prague?

Best airlines flying from Des Moines to Prague

Compare and see reviews for airlines that fly from Des Moines to Prague with momondo

Traveling to a place near Prague?

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

How can momondo help me find flights from Des Moines to Prague?

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo