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Cheap flights from Des Moines to Prague from $794

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Prague departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Prague

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 7:35 pm
DSM
-
PRG
30h 35m
2 stops
Delta Logo
8:50 am - 4:49 pm
PRG
-
DSM
38h 59m
2 stops
$794Delta
Wed, Aug 26 - Mon, Sep 7
United Airlines Logo
5:21 pm - 4:05 pm
DSM
-
PRG
15h 44m
2 stops
United Airlines Logo
12:30 pm - 10:26 am
PRG
-
DSM
28h 56m
2 stops
$834United Airlines
Wed, Aug 26 - Sat, Sep 5
Lufthansa Logo
3:20 pm - 12:45 pm
DSM
-
PRG
14h 25m
2 stops
Lufthansa Logo
6:10 am - 2:16 pm
PRG
-
DSM
15h 06m
2 stops
$854Lufthansa
Wed, Aug 26 - Sun, Sep 6
United Airlines Logo
6:55 pm - 4:05 pm
DSM
-
PRG
14h 10m
2 stops
United Airlines Logo
1:25 pm - 11:44 pm
PRG
-
DSM
41h 19m
2 stops
$861United Airlines
Wed, Aug 12 - Mon, Aug 17
American Airlines Logo
5:41 am - 8:15 am
DSM
-
PRG
19h 34m
1 stop
American Airlines Logo
10:15 am - 10:06 pm
PRG
-
DSM
18h 51m
1 stop
$892American Airlines
Thu, Aug 27 - Sun, Sep 6
American Airlines Logo
1:07 pm - 8:15 am
DSM
-
PRG
12h 08m
1 stop
American Airlines Logo
10:15 am - 12:20 am
PRG
-
DSM
21h 05m
2 stops
$896American Airlines
Thu, Aug 27 - Sun, Sep 6
Lufthansa Logo
3:20 pm - 4:05 pm
DSM
-
PRG
17h 45m
2 stops
Lufthansa Logo
6:10 am - 2:16 pm
PRG
-
DSM
15h 06m
2 stops
$899Lufthansa
Thu, Aug 27 - Sun, Sep 6
Delta Logo
10:59 am - 10:50 am
DSM
-
PRG
16h 51m
2 stops
Delta Logo
6:00 am - 8:59 pm
PRG
-
DSM
21h 59m
2 stops
$904Delta
Thu, Aug 27 - Sun, Sep 6
United Airlines Logo
6:55 pm - 4:05 pm
DSM
-
PRG
14h 10m
2 stops
United Airlines Logo
6:00 am - 2:16 pm
PRG
-
DSM
15h 16m
2 stops
$907United Airlines
Thu, Aug 27 - Mon, Sep 7
United Airlines Logo
8:00 am - 11:00 am
DSM
-
PRG
20h 00m
3 stops
United Airlines Logo
11:45 am - 10:30 pm
PRG
-
DSM
17h 45m
2 stops
$908United Airlines
Thu, Aug 27 - Sun, Sep 6

American Airlines flights from Des Moines to Prague

Our best American Airlines deals on Des Moines to Prague flight tickets
American Airlines
Aug 27
DSM5:41 amDes Moines
19h 34m
1 stop
PRG8:15 amVáclav Havel Prague
Sep 6
PRG10:15 amVáclav Havel Prague
18h 51m
1 stop
DSM10:06 pmDes Moines
$892
American Airlines
Aug 27
DSM1:07 pmDes Moines
12h 08m
1 stop
PRG8:15 amVáclav Havel Prague
Sep 6
PRG10:15 amVáclav Havel Prague
21h 05m
2 stops
DSM12:20 amDes Moines
$896
American Airlines
Aug 12
DSM7:37 pmDes Moines
18h 13m
2 stops
PRG8:50 pmVáclav Havel Prague
Aug 17
PRG10:15 amVáclav Havel Prague
18h 51m
1 stop
DSM10:06 pmDes Moines
$941

Delta flights from Des Moines to Prague

Our best Delta deals on Des Moines to Prague flight tickets
Delta
Aug 26
DSM6:00 amDes Moines
30h 35m
2 stops
PRG7:35 pmVáclav Havel Prague
Sep 7
PRG8:50 amVáclav Havel Prague
38h 59m
2 stops
DSM4:49 pmDes Moines
$794
Delta
Aug 27
DSM10:59 amDes Moines
16h 51m
2 stops
PRG10:50 amVáclav Havel Prague
Sep 6
PRG6:00 amVáclav Havel Prague
21h 59m
2 stops
DSM8:59 pmDes Moines
$904
Delta
Aug 28
DSM6:35 pmDes Moines
16h 05m
2 stops
PRG5:40 pmVáclav Havel Prague
Sep 7
PRG2:30 pmVáclav Havel Prague
30h 37m
2 stops
DSM2:07 pmDes Moines
$915

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 28, 2026.
Use the filters below to find and compare flights from Des Moines to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/26

6:00 am-7:35 pm

2 stops30h 35m

Václav Havel Prague

Mon 9/7

8:50 am-4:49 pm

2 stops38h 59m

$794

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/26

5:21 pm-4:05 pm

2 stops15h 44m

Václav Havel Prague

Sat 9/5

12:30 pm-10:26 am

2 stops28h 56m

$834

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/26

3:20 pm-12:45 pm

2 stops14h 25m

Václav Havel Prague

Sun 9/6

6:10 am-2:16 pm

2 stops15h 06m

$854

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 8/12

6:55 pm-4:05 pm

2 stops14h 10m

Václav Havel Prague

Mon 8/17

1:25 pm-11:44 pm

2 stops41h 19m

$861

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/27

5:41 am-8:15 am

1 stop19h 34m

Václav Havel Prague

Sun 9/6

10:15 am-10:06 pm

1 stop18h 51m

$892

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/27

1:07 pm-8:15 am

1 stop12h 08m

Václav Havel Prague

Sun 9/6

10:15 am-12:20 am

2 stops21h 05m

$896

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/27

3:20 pm-4:05 pm

2 stops17h 45m

Václav Havel Prague

Sun 9/6

6:10 am-2:16 pm

2 stops15h 06m

$899

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/27

10:59 am-10:50 am

2 stops16h 51m

Václav Havel Prague

Sun 9/6

6:00 am-8:59 pm

2 stops21h 59m

$904
Quickest round-trip

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/27

6:55 pm-4:05 pm

2 stops14h 10m

Václav Havel Prague

Mon 9/7

6:00 am-2:16 pm

2 stops15h 16m

$907

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 8/27

8:00 am-11:00 am

3 stops20h 00m

Václav Havel Prague

Sun 9/6

11:45 am-10:30 pm

2 stops17h 45m

$908

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Prague from

How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 6% on your flight if you consider stops on a Des Moines to Prague flight.

When to book flights from Des Moines to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Prague according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Fastest flight time

14h 10m

Direct flights

None
The fastest flight from Des Moines to Prague takes 14h 10m
There are no direct flights from Des Moines to Prague. There are no popular flight routes from Des Moines to Prague.
Search flight deals

Frequently asked questions about flying from Des Moines to Prague

  • How far is Des Moines to Václav Havel Prague by plane?

    A flight from Des Moines to Václav Havel Prague will travel around 4755.3 mi. Flights usually cover this in 14h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

    Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.

  • What documentation or ID do you need to fly to Václav Havel Prague Airport?

    The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Prague?

Book flights to Prague if you plan to visit one of these locations
Český Krumlov
Pilsen
Liberec

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Prague from Des Moines.

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

momondo does allow users to show only those flights to Prague from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Prague?

momondo provides multiple filters to help you find the best flight to Prague from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Prague from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Find better results for your trip to the Czech Republic

Cabin classes currently available on flights to Prague

List of cabin classes available on flights landing in Prague. Availability may vary depending on flight origin and airline.
First Class to Prague
Business Class to Praguefrom $2,837