What is the cheapest airline that flies from Des Moines to Václav Havel Prague?

American Airlines, Air Canada, and Lufthansa are the most popular carriers operating from Des Moines to Václav Havel Prague

When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?

As of December 2025, there is 1 operator available to choose from for flights from Des Moines Airport to Václav Havel Prague Airport.

How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.

What documentation or ID do you need to fly to Václav Havel Prague Airport?

The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$371 Cheap Flights from Des Moines to Prague in 2025/26

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11:42 am - 1:15 pmDSM-PRG

18h 33m2 stops

6:50 am - 9:04 pmPRG-DSM

21h 14m2 stops

$443British Airways

Find Deal

mié., ene. 14 - mié., ene. 21

5:51 pm - 5:30 pmDSM-PRG

16h 39m2 stops

6:50 am - 11:08 pmPRG-DSM

23h 18m2 stops

$449American Airlines

Find Deal

mié., ene. 14 - mié., ene. 21

5:01 pm - 5:30 pmDSM-PRG

17h 29m2 stops

6:50 am - 9:04 pmPRG-DSM

21h 14m2 stops

$450American Airlines

Find Deal

mié., ene. 14 - mié., ene. 21

11:35 am - 6:50 pmDSM-PRG

24h 15m2 stops

7:35 pm - 11:23 pmPRG-DSM

34h 48m2 stops

$451Multiple Airlines

Find Deal

mié., ene. 14 - mié., ene. 21

5:21 am - 6:50 pmDSM-PRG

30h 29m2 stops

7:35 pm - 11:23 pmPRG-DSM

34h 48m2 stops

$452Multiple Airlines

Find Deal

lun., ene. 12 - lun., ene. 19

11:35 am - 6:50 pmDSM-PRG

24h 15m2 stops

7:35 pm - 11:23 pmPRG-DSM

34h 48m2 stops

$454Multiple Airlines

Find Deal

mié., ene. 14 - mié., ene. 21

6:48 pm - 10:25 pmDSM-PRG

20h 37m2 stops

10:25 am - 9:50 pmPRG-DSM

18h 25m2 stops

$457Lufthansa

Find Deal

jue., ene. 15 - jue., ene. 22

5:21 am - 6:50 pmDSM-PRG

30h 29m2 stops

7:35 pm - 11:23 pmPRG-DSM

34h 48m2 stops

$460Multiple Airlines

Find Deal

mié., ene. 14 - mié., ene. 21

5:01 pm - 5:30 pmDSM-PRG

17h 29m2 stops

9:20 pm - 9:04 pmPRG-DSM

30h 44m2 stops

$462British Airways

Find Deal

mar., ene. 13 - mar., ene. 20

11:42 am - 12:55 pmDSM-PRG

18h 13m2 stops

9:20 pm - 9:04 pmPRG-DSM

30h 44m2 stops

$463British Airways

Find Deal

mar., ene. 13 - mar., ene. 20

British Airways flights from Des Moines to Prague

Our best British Airways deals on Des Moines to Prague flight tickets

British Airways

Jan 14

DSM11:42 amDes Moines

18h 33m

2 stops

PRG1:15 pmVáclav Havel Prague

Jan 21

PRG6:50 amVáclav Havel Prague

21h 14m

2 stops

DSM9:04 pmDes Moines

$443

Find similar

British Airways

Apr 20

DSM6:19 pmDes Moines

21h 41m

2 stops

PRG11:00 pmVáclav Havel Prague

Apr 27

PRG8:55 pmVáclav Havel Prague

28h 09m

2 stops

DSM6:04 pmDes Moines

$446

Find similar

British Airways

Jan 13

DSM5:01 pmDes Moines

17h 29m

2 stops

PRG5:30 pmVáclav Havel Prague

Jan 20

PRG9:20 pmVáclav Havel Prague

30h 44m

2 stops

DSM9:04 pmDes Moines

$462

Find similar

American Airlines flights from Des Moines to Prague

Our best American Airlines deals on Des Moines to Prague flight tickets

American Airlines

Jan 14

DSM5:51 pmDes Moines

16h 39m

2 stops

PRG5:30 pmVáclav Havel Prague

Jan 21

PRG6:50 amVáclav Havel Prague

23h 18m

2 stops

DSM11:08 pmDes Moines

$449

Find similar

American Airlines

Jan 14

DSM5:01 pmDes Moines

17h 29m

2 stops

PRG5:30 pmVáclav Havel Prague

Jan 21

PRG6:50 amVáclav Havel Prague

21h 14m

2 stops

DSM9:04 pmDes Moines

$450

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mié. 1/14

11:42 am-1:15 pm

2 stops18h 33m

Václav Havel Prague

mié. 1/21

6:50 am-9:04 pm

2 stops21h 14m

$443

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mié. 1/14

5:51 pm-5:30 pm

2 stops16h 39m

Václav Havel Prague

mié. 1/21

6:50 am-11:08 pm

2 stops23h 18m

$449

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mié. 1/14

5:01 pm-5:30 pm

2 stops17h 29m

Václav Havel Prague

mié. 1/21

6:50 am-9:04 pm

2 stops21h 14m

$450

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mié. 1/14

11:35 am-6:50 pm

2 stops24h 15m

Václav Havel Prague

mié. 1/21

7:35 pm-11:23 pm

2 stops34h 48m

$451

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

lun. 1/12

5:21 am-6:50 pm

2 stops30h 29m

Václav Havel Prague

lun. 1/19

7:35 pm-11:23 pm

2 stops34h 48m

$452

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mié. 1/14

11:35 am-6:50 pm

2 stops24h 15m

Václav Havel Prague

mié. 1/21

7:35 pm-11:23 pm

2 stops34h 48m

$454

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

jue. 1/15

6:48 pm-10:25 pm

2 stops20h 37m

Václav Havel Prague

jue. 1/22

10:25 am-9:50 pm

2 stops18h 25m

$457

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mié. 1/14

5:21 am-6:50 pm

2 stops30h 29m

Václav Havel Prague

mié. 1/21

7:35 pm-11:23 pm

2 stops34h 48m

$460

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mar. 1/13

5:01 pm-5:30 pm

2 stops17h 29m

Václav Havel Prague

mar. 1/20

9:20 pm-9:04 pm

2 stops30h 44m

$462

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

mar. 1/13

11:42 am-12:55 pm

2 stops18h 13m

Václav Havel Prague

mar. 1/20

9:20 pm-9:04 pm

2 stops30h 44m

$463

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Prague?

The cheapest day to depart from Des Moines to Prague is on a Tuesday. Travelers who choose to depart for Prague on a Tuesday will often find tickets for as low as $816. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Prague for around $1,811.

What is the cheapest time of day to depart on your flight to Prague?

According to our data, the cheapest time of day to fly to Prague is in the afternoon. momondo users have found flights departing from Des Moines to Prague in the afternoon for as low as $1,080. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $1,157. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Prague flight.

When to book flights from Des Moines to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Prague according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Fastest flight time	14h 25m
Direct flights	None

The fastest flight from Des Moines to Prague takes 14h 25m

There are no direct flights from Des Moines to Prague. There are no popular flight routes from Des Moines to Prague.

Search flight deals

How far is Des Moines to Václav Havel Prague by plane?
A flight from Des Moines to Václav Havel Prague will travel around 4755.3 mi. Flights usually cover this in 13h 21m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?
Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?
As of December 2025, there is 1 operator available to choose from for flights from Des Moines Airport to Václav Havel Prague Airport.
How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.
What documentation or ID do you need to fly to Václav Havel Prague Airport?
The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Des Moines to Prague?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Prague is United Airlines (100% of total bookings).

Best airlines flying from Des Moines to Prague

Compare and see reviews for airlines that fly from Des Moines to Prague with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $597	Free Cancellation	Rating 7.4 9,065 reviews		Search United Airlines flights

Český Krumlov

Pilsen

Liberec

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Prague from Des Moines.

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

momondo does allow users to show only those flights to Prague from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Prague?

momondo provides multiple filters to help you find the best flight to Prague from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Prague from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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United Airlines

Cheap flights from Des Moines to Prague from $371

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Prague departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

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Price Alerts

Find the cheapest flights from Des Moines to Prague

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British Airways flights from Des Moines to Prague

Our best British Airways deals on Des Moines to Prague flight tickets

American Airlines flights from Des Moines to Prague

Our best American Airlines deals on Des Moines to Prague flight tickets

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Use the filters below to find and compare flights from Des Moines to Prague that are best for you.

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How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Prague?

What is the cheapest time of day to depart on your flight to Prague?

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Prague flight.

What is the cheapest airline that flies from Des Moines to Václav Havel Prague?

American Airlines, Air Canada, and Lufthansa are the most popular carriers operating from Des Moines to Václav Havel Prague

When to book flights from Des Moines to Prague

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Fastest flight time

Direct flights

How far is Des Moines to Václav Havel Prague by plane?

When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?

How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

What documentation or ID do you need to fly to Václav Havel Prague Airport?

What is the most popular airline from Des Moines to Prague?

Best airlines flying from Des Moines to Prague

Compare and see reviews for airlines that fly from Des Moines to Prague with momondo

Traveling to a place near Prague?

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

How can momondo help me find flights from Des Moines to Prague?

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo