Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Des Moines to Prague from $444

1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Des Moines to Prague

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
6:45 pm - 10:40 pmDSM  Des Moines-PRG Václav Havel Prague
20h 55m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Lufthansa Logo
10:20 am - 10:59 pmPRG  Václav Havel Prague-DSM Des Moines
19h 39m2 stops Frankfurt am Main Chicago O'Hare Intl
$777Lufthansa
Wed, Nov 18 - Fri, Nov 27
Lufthansa Logo
6:45 pm - 4:05 pmDSM  Des Moines-PRG Václav Havel Prague
14h 20m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Lufthansa Logo
7:05 am - 5:28 pmPRG  Václav Havel Prague-DSM Des Moines
17h 23m2 stops Frankfurt am Main Chicago O'Hare Intl
$787Lufthansa
Tue, Nov 17 - Fri, Nov 27
United Airlines Logo
8:00 am - 10:50 amDSM  Des Moines-PRG Václav Havel Prague
19h 50m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Brussels Bruxelles-National
United Airlines Logo
7:05 am - 5:28 pmPRG  Václav Havel Prague-DSM Des Moines
17h 23m2 stops Frankfurt am Main Chicago O'Hare Intl
$801United Airlines
Tue, Nov 17 - Fri, Nov 27
Multiple Airlines Logo
1:24 pm - 8:55 amDSM  Des Moines-PRG Václav Havel Prague
12h 31m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Multiple Airlines Logo
12:30 pm - 11:48 pmPRG  Václav Havel Prague-DSM Des Moines
18h 18m2 stops Toronto Pearson Intl Denver Intl
$823Multiple Airlines
Wed, Oct 7 - Wed, Oct 14
Multiple Airlines Logo
1:24 pm - 8:55 amDSM  Des Moines-PRG Václav Havel Prague
12h 31m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Multiple Airlines Logo
12:30 pm - 11:48 pmPRG  Václav Havel Prague-DSM Des Moines
18h 18m2 stops Toronto Pearson Intl Denver Intl
$825Multiple Airlines
Wed, Oct 7 - Wed, Oct 14
Air Canada Logo
9:55 am - 9:40 amDSM  Des Moines-PRG Václav Havel Prague
16h 45m3 stops Chicago O'Hare Intl Toronto Pearson Intl Frankfurt am Main
Air Canada Logo
7:05 am - 7:16 pmPRG  Václav Havel Prague-DSM Des Moines
19h 11m3 stops Frankfurt am Main Toronto Pearson Intl Chicago O'Hare Intl
$829Air Canada
Tue, Nov 17 - Fri, Nov 27
Multiple Airlines Logo
1:24 pm - 8:55 amDSM  Des Moines-PRG Václav Havel Prague
12h 31m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Multiple Airlines Logo
12:30 pm - 9:23 pmPRG  Václav Havel Prague-DSM Des Moines
15h 53m2 stops Toronto Pearson Intl Chicago O'Hare Intl
$830Multiple Airlines
Wed, Oct 7 - Wed, Oct 14
Lufthansa Logo
1:24 pm - 8:55 amDSM  Des Moines-PRG Václav Havel Prague
12h 31m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
Lufthansa Logo
6:15 am - 5:48 pmPRG  Václav Havel Prague-DSM Des Moines
18h 33m2 stops Munich Franz Josef Strauss Chicago O'Hare Intl
$842Lufthansa
Wed, Oct 7 - Wed, Oct 14
KLM Logo
7:51 pm - 5:40 pmDSM  Des Moines-PRG Václav Havel Prague
14h 49m2 stops Minneapolis St Paul Amsterdam Schiphol
KLM Logo
8:20 pm - 7:11 pmPRG  Václav Havel Prague-DSM Des Moines
29h 51m2 stops Amsterdam Schiphol Minneapolis St Paul
$843KLM
Mon, Oct 12 - Mon, Oct 19
Delta Logo
6:55 am - 10:50 amDSM  Des Moines-PRG Václav Havel Prague
20h 55m2 stops Minneapolis St Paul Paris Charles de Gaulle
Delta Logo
2:30 pm - 2:25 pmPRG  Václav Havel Prague-DSM Des Moines
30h 55m2 stops Amsterdam Schiphol Minneapolis St Paul
$848Delta
Mon, Oct 12 - Mon, Oct 19

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

KLM flights from Des Moines to Prague

Our best KLM deals on Des Moines to Prague flight tickets
KLM
Oct 12
DSM7:51 pmDes Moines
14h 49m
2 stops
PRG5:40 pmVáclav Havel Prague
Oct 19
PRG8:20 pmVáclav Havel Prague
29h 51m
2 stops
DSM7:11 pmDes Moines
$843
KLM
Oct 9
DSM10:57 amDes Moines
14h 23m
2 stops
PRG8:20 amVáclav Havel Prague
Oct 16
PRG6:00 amVáclav Havel Prague
15h 45m
2 stops
DSM2:45 pmDes Moines
$883

Lufthansa flights from Des Moines to Prague

Our best Lufthansa deals on Des Moines to Prague flight tickets
Lufthansa
Nov 18
DSM6:45 pmDes Moines
20h 55m
2 stops
PRG10:40 pmVáclav Havel Prague
Nov 27
PRG10:20 amVáclav Havel Prague
19h 39m
2 stops
DSM10:59 pmDes Moines
$777
Lufthansa
Nov 17
DSM6:45 pmDes Moines
14h 20m
2 stops
PRG4:05 pmVáclav Havel Prague
Nov 27
PRG7:05 amVáclav Havel Prague
17h 23m
2 stops
DSM5:28 pmDes Moines
$787
Lufthansa
Oct 7
DSM1:24 pmDes Moines
12h 31m
2 stops
PRG8:55 amVáclav Havel Prague
Oct 14
PRG6:15 amVáclav Havel Prague
18h 33m
2 stops
DSM5:48 pmDes Moines
$842

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Wed 11/18

6:45 pm-10:40 pm

2 stops20h 55m

Václav Havel Prague

Fri 11/27

10:20 am-10:59 pm

2 stops19h 39m

$777

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Tue 11/17

6:45 pm-4:05 pm

2 stops14h 20m

Václav Havel Prague

Fri 11/27

7:05 am-5:28 pm

2 stops17h 23m

$787

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Tue 11/17

8:00 am-10:50 am

3 stops19h 50m

Václav Havel Prague

Fri 11/27

7:05 am-5:28 pm

2 stops17h 23m

$801

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Wed 10/7

1:24 pm-8:55 am

2 stops12h 31m

Václav Havel Prague

Wed 10/14

12:30 pm-11:48 pm

2 stops18h 18m

$823

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Wed 10/7

1:24 pm-8:55 am

2 stops12h 31m

Václav Havel Prague

Wed 10/14

12:30 pm-11:48 pm

2 stops18h 18m

$825

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Tue 11/17

9:55 am-9:40 am

3 stops16h 45m

Václav Havel Prague

Fri 11/27

7:05 am-7:16 pm

3 stops19h 11m

$829
Quickest round-trip

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Wed 10/7

1:24 pm-8:55 am

2 stops12h 31m

Václav Havel Prague

Wed 10/14

12:30 pm-9:23 pm

2 stops15h 53m

$830

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Wed 10/7

1:24 pm-8:55 am

2 stops12h 31m

Václav Havel Prague

Wed 10/14

6:15 am-5:48 pm

2 stops18h 33m

$842

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Mon 10/12

7:51 pm-5:40 pm

2 stops14h 49m

Václav Havel Prague

Mon 10/19

8:20 pm-7:11 pm

2 stops29h 51m

$843

Des MoinesPrague

DSM Des Moines - PRG Václav Havel Prague

DSMPRG

Des Moines

Mon 10/12

6:55 am-10:50 am

2 stops20h 55m

Václav Havel Prague

Mon 10/19

2:30 pm-2:25 pm

2 stops30h 55m

$848

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

See travel insights to Prague from

How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 30% on your flight if you consider stops on a Des Moines to Prague flight.

When to book flights from Des Moines to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Prague according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Best Price Found

$444

Fastest flight time

12h 31m

Direct flights

None
The best one-way flight to Prague from Des Moines in the past 72 hours is $444. The best round-trip flight deal from Des Moines to Prague found on momondo in the last 72 hours is $777.
The fastest flight from Des Moines to Prague takes 12h 31m
There are no direct flights from Des Moines to Prague. There are no popular flight routes from Des Moines to Prague.
Search flight deals

Frequently asked questions about flying from Des Moines to Prague

  • How far is Des Moines to Václav Havel Prague by plane?

    A flight from Des Moines to Václav Havel Prague will travel around 4755.3 mi. Flights usually cover this in 12h 31m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

    Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.

  • What documentation or ID do you need to fly to Václav Havel Prague Airport?

    The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Prague?

Book flights to Prague if you plan to visit one of these locations
Český Krumlov
Pilsen
Liberec

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Prague from Des Moines.

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

momondo does allow users to show only those flights to Prague from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Prague?

momondo provides multiple filters to help you find the best flight to Prague from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Prague from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 9/27
Sun 10/4
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Czech Republic

Cabin classes currently available on flights to Prague

First Class to Prague
Business Class to Praguefrom $3,588