What is the cheapest airline that flies from Des Moines to Václav Havel Prague?

American Airlines and Air Canada are the most popular carriers operating from Des Moines to Václav Havel Prague

When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?

As of September 2025, there is 1 operator available to choose from for flights from Des Moines Airport to Václav Havel Prague Airport.

How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.

What documentation or ID do you need to fly to Václav Havel Prague Airport?

The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$422 Cheap Flights from Des Moines to Prague in 2025/26

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Des Moines to Prague

Round-trip

One-way

Last minute

Cheap round-trip flights

6:07 pm - 10:50 pmDSM-PRG

22h 43m2 stops

9:30 pm - 6:10 pmPRG-DSM

27h 40m2 stops

$535British Airways

Find Deal

Wed, Oct 29 - Wed, Nov 5

6:07 pm - 8:40 pmDSM-PRG

20h 33m2 stops

9:30 pm - 6:10 pmPRG-DSM

27h 40m2 stops

$536British Airways

Find Deal

Wed, Oct 29 - Wed, Nov 5

2:13 pm - 9:45 amDSM-PRG

37h 32m2 stops

7:20 pm - 10:30 pmPRG-DSM

34h 10m2 stops

$550Scandinavian Airlines

Find Deal

Thu, Oct 30 - Thu, Nov 6

3:48 pm - 6:05 pmDSM-PRG

20h 17m2 stops

6:45 am - 11:50 pmPRG-DSM

24h 05m2 stops

$583American Airlines

Find Deal

Thu, Oct 30 - Thu, Nov 6

5:42 pm - 6:05 pmDSM-PRG

18h 23m2 stops

6:45 am - 10:54 pmPRG-DSM

23h 09m2 stops

$585American Airlines

Find Deal

Thu, Oct 30 - Thu, Nov 6

3:48 pm - 2:00 pmDSM-PRG

16h 12m2 stops

11:00 am - 10:59 pmPRG-DSM

18h 59m2 stops

$586American Airlines

Find Deal

Fri, Oct 31 - Fri, Nov 7

1:05 pm - 1:05 pmDSM-PRG

18h 00m3 stops

7:35 am - 9:32 pmPRG-DSM

20h 57m3 stops

$957Air Canada

Find Deal

Thu, Oct 30 - Thu, Nov 6

1:05 pm - 1:05 pmDSM-PRG

18h 00m3 stops

7:35 am - 9:32 pmPRG-DSM

20h 57m3 stops

$959Air Canada

Find Deal

Thu, Oct 30 - Thu, Nov 6

8:30 am - 9:45 amDSM-PRG

43h 15m3 stops

6:30 am - 11:50 pmPRG-DSM

24h 20m2 stops

$1,118Multiple Airlines

Find Deal

Fri, Oct 31 - Fri, Nov 7

8:47 pm - 8:10 pmDSM-PRG

41h 23m3 stops

5:55 am - 11:50 pmPRG-DSM

24h 55m2 stops

$1,219Multiple Airlines

Find Deal

Thu, Oct 30 - Thu, Nov 6

British Airways flights from Des Moines to Prague

Our best British Airways deals on Des Moines to Prague flight tickets

British Airways

Oct 29

DSM6:07 pmDes Moines

22h 43m

2 stops

PRG10:50 pmVáclav Havel Prague

Nov 5

PRG9:30 pmVáclav Havel Prague

27h 40m

2 stops

DSM6:10 pmDes Moines

$535

Find similar

British Airways

Oct 29

DSM6:07 pmDes Moines

20h 33m

2 stops

PRG8:40 pmVáclav Havel Prague

Nov 5

PRG9:30 pmVáclav Havel Prague

27h 40m

2 stops

DSM6:10 pmDes Moines

$536

Find similar

British Airways

Dec 15

DSM6:28 pmDes Moines

35h 27m

2 stops

PRG12:55 pmVáclav Havel Prague

Dec 29

PRG9:35 pmVáclav Havel Prague

27h 32m

2 stops

DSM6:07 pmDes Moines

$3,340

Find similar

American Airlines flights from Des Moines to Prague

Our best American Airlines deals on Des Moines to Prague flight tickets

American Airlines

Oct 30

DSM3:48 pmDes Moines

20h 17m

2 stops

PRG6:05 pmVáclav Havel Prague

Nov 6

PRG6:45 amVáclav Havel Prague

24h 05m

2 stops

DSM11:50 pmDes Moines

$583

Find similar

American Airlines

Oct 30

DSM5:42 pmDes Moines

18h 23m

2 stops

PRG6:05 pmVáclav Havel Prague

Nov 6

PRG6:45 amVáclav Havel Prague

23h 09m

2 stops

DSM10:54 pmDes Moines

$585

Find similar

American Airlines

Oct 31

DSM3:48 pmDes Moines

16h 12m

2 stops

PRG2:00 pmVáclav Havel Prague

Nov 7

PRG11:00 amVáclav Havel Prague

18h 59m

2 stops

DSM10:59 pmDes Moines

$586

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 10/29

6:07 pm-10:50 pm

2 stops22h 43m

Václav Havel Prague

Wed 11/5

9:30 pm-6:10 pm

2 stops27h 40m

$535

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 10/29

6:07 pm-8:40 pm

2 stops20h 33m

Václav Havel Prague

Wed 11/5

9:30 pm-6:10 pm

2 stops27h 40m

$536

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

2:13 pm-9:45 am

2 stops37h 32m

Václav Havel Prague

Thu 11/6

7:20 pm-10:30 pm

2 stops34h 10m

$550

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

3:48 pm-6:05 pm

2 stops20h 17m

Václav Havel Prague

Thu 11/6

6:45 am-11:50 pm

2 stops24h 05m

$583

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

5:42 pm-6:05 pm

2 stops18h 23m

Václav Havel Prague

Thu 11/6

6:45 am-10:54 pm

2 stops23h 09m

$585

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 10/31

3:48 pm-2:00 pm

2 stops16h 12m

Václav Havel Prague

Fri 11/7

11:00 am-10:59 pm

2 stops18h 59m

$586

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

1:05 pm-1:05 pm

3 stops18h 00m

Václav Havel Prague

Thu 11/6

7:35 am-9:32 pm

3 stops20h 57m

$957

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

1:05 pm-1:05 pm

3 stops18h 00m

Václav Havel Prague

Thu 11/6

7:35 am-9:32 pm

3 stops20h 57m

$959

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 10/31

8:30 am-9:45 am

3 stops43h 15m

Václav Havel Prague

Fri 11/7

6:30 am-11:50 pm

2 stops24h 20m

$1,118

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

8:47 pm-8:10 pm

3 stops41h 23m

Václav Havel Prague

Thu 11/6

5:55 am-11:50 pm

2 stops24h 55m

$1,219

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Prague?

The cheapest day to depart from Des Moines to Prague is on a Tuesday. Travelers who choose to depart for Prague on a Tuesday will often find tickets for as low as $816. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Prague for around $1,811.

What is the cheapest time of day to depart on your flight to Prague?

According to our data, the cheapest time of day to fly to Prague is in the afternoon. momondo users have found flights departing from Des Moines to Prague in the afternoon for as low as $1,080. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $1,157. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Prague flight.

When to book flights from Des Moines to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Prague according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Direct flights	None

There are no direct flights from Des Moines to Prague. There are no popular flight routes from Des Moines to Prague.

Search flight deals

How far is Des Moines to Václav Havel Prague by plane?
A flight from Des Moines to Václav Havel Prague will travel around 4755.3 mi. Flights usually cover this in 16h 12m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?
Prices for flights from Des Moines Airport to Václav Havel Prague Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?
As of September 2025, there is 1 operator available to choose from for flights from Des Moines Airport to Václav Havel Prague Airport.
How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Václav Havel Prague Airport.
What documentation or ID do you need to fly to Václav Havel Prague Airport?
The travel and health documents required for your trip to Václav Havel Prague Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Václav Havel Prague Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Des Moines to Prague?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Prague is United Airlines (100% of total bookings).

Best airlines flying from Des Moines to Prague

Compare and see reviews for airlines that fly from Des Moines to Prague with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $588	Free Cancellation	Rating 7.4 8,924 reviews		Search United Airlines flights

Český Krumlov

Pilsen

Liberec

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Prague from Des Moines.

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

momondo does allow users to show only those flights to Prague from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Prague?

momondo provides multiple filters to help you find the best flight to Prague from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Prague from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Thu 10/16

Thu 10/23

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Cheap flights from Des Moines to Prague from $422

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Prague departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Des Moines to Prague

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

British Airways flights from Des Moines to Prague

Our best British Airways deals on Des Moines to Prague flight tickets

American Airlines flights from Des Moines to Prague

Our best American Airlines deals on Des Moines to Prague flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Prague that are best for you.

See travel insights to Prague from

How to get the cheapest flight ticket from Des Moines to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Prague?

What is the cheapest time of day to depart on your flight to Prague?

Can stopping save me money on Des Moines to Prague flights?

You could potentially save up to 50% on your flight if you consider stops on a Des Moines to Prague flight.

What is the cheapest airline that flies from Des Moines to Václav Havel Prague?

American Airlines and Air Canada are the most popular carriers operating from Des Moines to Václav Havel Prague

When to book flights from Des Moines to Prague

Cheap Des Moines to Prague (DSM to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Prague

Direct flights

How far is Des Moines to Václav Havel Prague by plane?

When did momondo last update prices for flights from Des Moines Airport to Václav Havel Prague Airport?

How many operators does momondo search for flights from Des Moines Airport to Václav Havel Prague Airport?

How old do you have to be to fly from Des Moines Airport to Václav Havel Prague Airport?

What documentation or ID do you need to fly to Václav Havel Prague Airport?

What is the most popular airline from Des Moines to Prague?

Best airlines flying from Des Moines to Prague

Compare and see reviews for airlines that fly from Des Moines to Prague with momondo

Traveling to a place near Prague?

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Prague?

Can I find flights from Des Moines to Prague with flexible booking policies on momondo?

How can momondo help me find flights from Des Moines to Prague?

I’m not ready to book a flight from Des Moines to Prague right now. Can momondo alert me if prices change?

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo