What airlines fly to Ohio?

United Airlines, Delta and Southwest are the top three most popular airlines that fly to Ohio from Des Moines according to our data. United Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Ohio. Keep in mind that there are 3 different airlines that fly to Ohio on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Ohio?

Frontier, Delta, and United Airlines are the most popular carriers operating from Des Moines to Ohio

When did momondo last update prices for flights from Des Moines Airport to Ohio?

Prices for flights from Des Moines Airport to Ohio refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Ohio?

There are 3 operators available for flights from Des Moines Airport to Ohio as of September 2026.

How old do you have to be to fly from Des Moines Airport to Ohio?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Ohio.

What documentation or ID do you need to fly to Ohio?

The travel and health documents required for your trip to Ohio can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Ohio. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$135 Cheap Flights from Des Moines to Ohio in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Ohio

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:25 pm - 3:40 pmDSM Des Moines-CLE Cleveland Hopkins Intl

18h 15m1 stop Denver Intl

5:20 pm - 7:35 pmCLE Cleveland Hopkins Intl-DSM Des Moines

27h 15m1 stop Denver Intl

$264Frontier

Mon, Oct 26 - Sun, Nov 1

5:30 am - 1:59 pmDSM Des Moines-CMH Columbus

7h 29m1 stop Atlanta Hartsfield-Jackson

8:05 am - 2:13 pmCMH Columbus-DSM Des Moines

7h 08m1 stop Atlanta Hartsfield-Jackson

$309Delta

Wed, Nov 18 - Wed, Dec 2

8:00 am - 1:10 pmDSM Des Moines-CMH Columbus

4h 10m1 stop Chicago O'Hare Intl

5:56 pm - 9:55 pmCMH Columbus-DSM Des Moines

4h 59m1 stop Chicago O'Hare Intl

$309United Airlines

Thu, Nov 5 - Mon, Nov 9

3:11 pm - 10:36 pmDSM Des Moines-CLE Cleveland Hopkins Intl

6h 25m1 stop Chicago O'Hare Intl

5:49 pm - 9:55 pmCLE Cleveland Hopkins Intl-DSM Des Moines

5h 06m1 stop Chicago O'Hare Intl

$309United Airlines

Mon, Oct 19 - Mon, Oct 26

9:26 am - 2:45 pmDSM Des Moines-CMH Columbus

4h 19m1 stop Chicago O'Hare Intl

8:11 am - 1:28 pmCMH Columbus-DSM Des Moines

6h 17m1 stop Chicago O'Hare Intl

$309American Airlines

Thu, Oct 29 - Tue, Nov 3

4:07 pm - 11:40 pmDSM Des Moines-CMH Columbus

6h 33m1 stop Atlanta Hartsfield-Jackson

4:24 pm - 9:00 pmCMH Columbus-DSM Des Moines

5h 36m1 stop Minneapolis St Paul

$309Delta

Sat, Oct 17 - Sat, Oct 24

12:25 pm - 6:55 pmDSM Des Moines-CMH Columbus

5h 30m1 stop Detroit Metropolitan Wayne County

11:08 am - 2:25 pmCMH Columbus-DSM Des Moines

4h 17m1 stop Minneapolis St Paul

$309Delta

Sat, Oct 17 - Sat, Oct 24

7:00 am - 3:30 pmDSM Des Moines-CMH Columbus

7h 30m1 stop Denver Intl

3:45 pm - 10:00 pmCMH Columbus-DSM Des Moines

7h 15m2 stops Baltimore/Washington Chicago Midway

$314Southwest

Tue, Dec 8 - Thu, Dec 10

12:45 pm - 10:05 pmDSM Des Moines-CVG Cincinnati Cinci./N. Kentucky

8h 20m2 stops Chicago Midway Baltimore/Washington

7:30 pm - 10:00 pmCVG Cincinnati Cinci./N. Kentucky-DSM Des Moines

3h 30m1 stop Chicago Midway

$314Southwest

Sat, Dec 12 - Mon, Dec 14

8:25 pm - 11:19 amDSM Des Moines-CVG Cincinnati Cinci./N. Kentucky

37h 54m2 stops Denver Intl Atlanta Hartsfield-Jackson

10:28 am - 5:02 pmCVG Cincinnati Cinci./N. Kentucky-DSM Des Moines

7h 34m1 stop Fort Lauderdale

$315Multiple Airlines

Mon, Oct 26 - Thu, Oct 29

Cheap last minute flights

Enter your travel dates to find the best prices.

10:05 am - 11:58 pmDSM Des Moines-CLE Cleveland Hopkins Intl

12h 53m1 stop Fort Myers SW Florida Intl

1:24 pm - 7:33 pmCLE Cleveland Hopkins Intl-DSM Des Moines

7h 09m1 stop Denver Intl

$430Multiple Airlines

Mon, Sep 28 - Mon, Oct 5

3:04 pm - 11:58 pmDSM Des Moines-CLE Cleveland Hopkins Intl

7h 54m1 stop Fort Myers SW Florida Intl

9:59 pm - 9:34 amCLE Cleveland Hopkins Intl-DSM Des Moines

12h 35m1 stop Orlando

$494Multiple Airlines

Fri, Sep 25 - Sun, Sep 27

10:05 am - 11:58 pmDSM Des Moines-CLE Cleveland Hopkins Intl

12h 53m1 stop Fort Myers SW Florida Intl

1:24 pm - 1:52 pmCLE Cleveland Hopkins Intl-DSM Des Moines

49h 28m2 stops Denver Intl Las Vegas Harry Reid Intl

$531Multiple Airlines

Mon, Sep 28 - Mon, Oct 5

11:27 am - 5:14 pmDSM Des Moines-CAK Akron/Canton

4h 47m1 stop Chicago O'Hare Intl

6:00 am - 10:31 amCAK Akron/Canton-DSM Des Moines

5h 31m1 stop Chicago O'Hare Intl

$544United Airlines

Fri, Sep 25 - Sun, Sep 27

5:45 am - 2:39 pmDSM Des Moines-CMH Columbus

7h 54m1 stop Denver Intl

7:17 am - 10:31 amCMH Columbus-DSM Des Moines

4h 14m1 stop Chicago O'Hare Intl

$550United Airlines

Tue, Sep 29 - Sat, Oct 3

6:00 am - 11:55 amDSM Des Moines-CMH Columbus

4h 55m1 stop Chicago O'Hare Intl

7:17 am - 10:31 amCMH Columbus-DSM Des Moines

4h 14m1 stop Chicago O'Hare Intl

$550United Airlines

Tue, Sep 29 - Sat, Oct 3

12:10 pm - 5:35 pmDSM Des Moines-CLE Cleveland Hopkins Intl

4h 25m1 stop Chicago Midway

6:20 pm - 10:55 pmCLE Cleveland Hopkins Intl-DSM Des Moines

5h 35m2 stops Lambert-St Louis Chicago Midway

$608Southwest

Sat, Sep 26 - Sun, Sep 27

12:10 pm - 5:35 pmDSM Des Moines-CLE Cleveland Hopkins Intl

4h 25m1 stop Chicago Midway

6:20 pm - 10:55 pmCLE Cleveland Hopkins Intl-DSM Des Moines

5h 35m2 stops Lambert-St Louis Chicago Midway

$608Southwest

Sat, Sep 26 - Sun, Sep 27

12:10 pm - 8:25 pmDSM Des Moines-CLE Cleveland Hopkins Intl

7h 15m2 stops Chicago Midway Nashville Intl

6:20 pm - 10:55 pmCLE Cleveland Hopkins Intl-DSM Des Moines

5h 35m2 stops Lambert-St Louis Chicago Midway

$613Southwest

Sat, Sep 26 - Sun, Sep 27

11:31 am - 6:10 pmDSM Des Moines-CLE Cleveland Hopkins Intl

5h 39m1 stop Atlanta Hartsfield-Jackson

6:00 am - 10:46 amCLE Cleveland Hopkins Intl-DSM Des Moines

5h 46m1 stop Atlanta Hartsfield-Jackson

$651Delta

Fri, Sep 25 - Sun, Sep 27

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Southwest flights from Des Moines to Ohio

Our best Southwest deals on Des Moines to Ohio flight tickets

Southwest

Dec 12

DSM12:45 pmDes Moines

8h 20m

2 stops

CVG10:05 pmCincinnati Cinci./N. Kentucky

Dec 14

CVG7:30 pmCincinnati Cinci./N. Kentucky

3h 30m

1 stop

DSM10:00 pmDes Moines

$314

Southwest

Dec 8

DSM6:00 amDes Moines

10h 25m

2 stops

CMH5:25 pmColumbus

Dec 10

CMH6:20 amColumbus

8h 55m

2 stops

DSM2:15 pmDes Moines

$319

Southwest

Oct 21

DSM5:35 amDes Moines

8h 15m

2 stops

CVG2:50 pmCincinnati Cinci./N. Kentucky

Oct 28

CVG8:35 amCincinnati Cinci./N. Kentucky

3h 55m

1 stop

DSM11:30 amDes Moines

$334

United Airlines flights from Des Moines to Ohio

Our best United Airlines deals on Des Moines to Ohio flight tickets

United Airlines

Oct 19

DSM3:11 pmDes Moines

6h 25m

1 stop

CLE10:36 pmCleveland Hopkins Intl

Oct 26

CLE5:49 pmCleveland Hopkins Intl

5h 06m

1 stop

DSM9:55 pmDes Moines

$309

United Airlines

Oct 15

DSM6:55 pmDes Moines

3h 59m

1 stop

CMH11:54 pmColumbus

Oct 17

CMH10:30 amColumbus

8h 18m

2 stops

DSM5:48 pmDes Moines

$314

United Airlines

Nov 24

DSM11:22 amDes Moines

4h 27m

1 stop

CLE4:49 pmCleveland Hopkins Intl

Dec 1

CLE5:56 pmCleveland Hopkins Intl

4h 29m

1 stop

DSM9:25 pmDes Moines

$336

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesCleveland

DSM Des Moines - CLE Cleveland Hopkins Intl

DSMCLE

Des Moines

Mon 10/26

8:25 pm-3:40 pm

1 stop18h 15m

Cleveland Hopkins Intl

Sun 11/1

5:20 pm-7:35 pm

1 stop27h 15m

$264

Des MoinesColumbus

DSM Des Moines - CMH Columbus

DSMCMH

Des Moines

Wed 11/18

5:30 am-1:59 pm

1 stop7h 29m

Columbus

Wed 12/2

8:05 am-2:13 pm

1 stop7h 08m

$309

Quickest round-trip

Des MoinesColumbus

DSM Des Moines - CMH Columbus

DSMCMH

Des Moines

Thu 11/5

8:00 am-1:10 pm

1 stop4h 10m

Columbus

Mon 11/9

5:56 pm-9:55 pm

1 stop4h 59m

$309

Des MoinesCleveland

DSM Des Moines - CLE Cleveland Hopkins Intl

DSMCLE

Des Moines

Mon 10/19

3:11 pm-10:36 pm

1 stop6h 25m

Cleveland Hopkins Intl

Mon 10/26

5:49 pm-9:55 pm

1 stop5h 06m

$309

Des MoinesColumbus

DSM Des Moines - CMH Columbus

DSMCMH

Des Moines

Thu 10/29

9:26 am-2:45 pm

1 stop4h 19m

Columbus

Tue 11/3

8:11 am-1:28 pm

1 stop6h 17m

$309

Des MoinesColumbus

DSM Des Moines - CMH Columbus

DSMCMH

Des Moines

Sat 10/17

4:07 pm-11:40 pm

1 stop6h 33m

Columbus

Sat 10/24

4:24 pm-9:00 pm

1 stop5h 36m

$309

Des MoinesColumbus

DSM Des Moines - CMH Columbus

DSMCMH

Des Moines

Sat 10/17

12:25 pm-6:55 pm

1 stop5h 30m

Columbus

Sat 10/24

11:08 am-2:25 pm

1 stop4h 17m

$309

Des MoinesColumbus

DSM Des Moines - CMH Columbus

DSMCMH

Des Moines

Tue 12/8

7:00 am-3:30 pm

1 stop7h 30m

Columbus

Thu 12/10

3:45 pm-10:00 pm

2 stops7h 15m

$314

Des MoinesCincinnati

DSM Des Moines - CVG Cincinnati Cinci./N. Kentucky

DSMCVG

Des Moines

Sat 12/12

12:45 pm-10:05 pm

2 stops8h 20m

Cincinnati Cinci./N. Kentucky

Mon 12/14

7:30 pm-10:00 pm

1 stop3h 30m

$314

Des MoinesCincinnati

DSM Des Moines - CVG Cincinnati Cinci./N. Kentucky

DSMCVG

Des Moines

Mon 10/26

8:25 pm-11:19 am

2 stops37h 54m

Cincinnati Cinci./N. Kentucky

Thu 10/29

10:28 am-5:02 pm

1 stop7h 34m

$315

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Ohio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Ohio?

In general, November is the cheapest month to fly from Des Moines to Ohio. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $365. If you are unable to visit Ohio during the month of November, then departing from Des Moines during the month January is also very affordable. Most momondo users find prices during this month for around $394.

Cheap Des Moines to Ohio flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Ohio

Best Price Found	$135
Fastest flight time	1h 45m
Direct flights	None

The best one-way flight to Ohio from Des Moines in the past 72 hours is $135. The best round-trip flight deal from Des Moines to Ohio found on momondo in the last 72 hours is $264.

The fastest flight from Des Moines to Ohio takes 1h 45m

There are no direct flights from Des Moines to Ohio. There are no popular flight routes from Des Moines to Ohio.

Search flight deals

Frequently asked questions about flying from Des Moines to Ohio

When did momondo last update prices for flights from Des Moines Airport to Ohio?
Prices for flights from Des Moines Airport to Ohio refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Ohio?
There are 3 operators available for flights from Des Moines Airport to Ohio as of September 2026.
How old do you have to be to fly from Des Moines Airport to Ohio?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Ohio.
What documentation or ID do you need to fly to Ohio?
The travel and health documents required for your trip to Ohio can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Ohio. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Ohio

Compare and see reviews for airlines that fly from Des Moines to Ohio with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $220	Free Cancellation	Rating 7.8 8,590 reviews	Search Delta flights
United Airlines	PriceFrom $225	Free Cancellation	Rating 7.4 10,226 reviews	Search United Airlines flights
Southwest	PriceFrom $331	Free Cancellation	Rating 8.0 4,196 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Ohio?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Ohio. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Ohio with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Ohio flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Ohio?

Once all potential Des Moines to Ohio flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Ohio right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Ohio flights. All you need is a valid email address and we will do the rest; it is that quick and easy.