Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to North Carolina from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to North Carolina departing on 3/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to North Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
11:00 am - 9:53 pm
DSM
-
RDU
9h 53m
1 stop
Frontier Logo
10:38 pm - 9:45 am
RDU
-
DSM
12h 07m
1 stop
$181Frontier
Tue, Mar 10 - Wed, Mar 11
Frontier Logo
11:00 am - 9:53 pm
DSM
-
RDU
9h 53m
1 stop
Frontier Logo
10:38 pm - 9:30 am
RDU
-
DSM
11h 52m
1 stop
$210Frontier
Tue, Mar 10 - Thu, Mar 12
American Airlines Logo
2:02 pm - 8:03 pm
DSM
-
TRI
5h 01m
1 stop
American Airlines Logo
4:16 pm - 11:48 pm
TRI
-
DSM
8h 32m
1 stop
$254American Airlines
Sat, Feb 28 - Tue, Mar 3
American Airlines Logo
2:00 pm - 8:50 pm
DSM
-
TRI
5h 50m
1 stop
American Airlines Logo
5:30 am - 10:44 am
TRI
-
DSM
6h 14m
1 stop
$259American Airlines
Tue, Feb 24 - Sat, Feb 28
Delta Logo
5:45 am - 1:49 pm
DSM
-
GSO
7h 04m
1 stop
Delta Logo
6:55 pm - 10:26 pm
GSO
-
DSM
4h 31m
1 stop
$269Delta
Wed, Jun 24 - Sun, Jun 28
Delta Logo
2:44 pm - 10:33 pm
DSM
-
AVL
6h 49m
1 stop
Delta Logo
5:43 am - 11:05 am
AVL
-
DSM
6h 22m
1 stop
$269Delta
Tue, Apr 14 - Sat, Apr 18
United Airlines Logo
3:24 pm - 8:42 pm
DSM
-
GSO
4h 18m
1 stop
United Airlines Logo
6:00 am - 2:27 pm
GSO
-
DSM
9h 27m
2 stops
$284United Airlines
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
11:30 am - 9:26 pm
DSM
-
GSO
8h 56m
2 stops
United Airlines Logo
6:00 am - 2:27 pm
GSO
-
DSM
9h 27m
2 stops
$289United Airlines
Tue, Feb 24 - Sat, Feb 28
Southwest Logo
4:20 pm - 10:25 pm
DSM
-
CLT
5h 05m
1 stop
Southwest Logo
8:00 am - 12:10 pm
CLT
-
DSM
5h 10m
1 stop
$292Southwest
Mon, Mar 9 - Mon, Mar 16
Southwest Logo
6:40 am - 3:20 pm
DSM
-
TYS
7h 40m
2 stops
Southwest Logo
8:15 am - 10:10 pm
TYS
-
DSM
14h 55m
2 stops
$304Southwest
Sat, May 2 - Tue, May 5

United Airlines flights from Des Moines to North Carolina

Our best United Airlines deals on Des Moines to North Carolina flight tickets
United Airlines
Feb 25
DSM3:24 pmDes Moines
4h 21m
1 stop
AVL8:45 pmAsheville Regional
Mar 1
AVL6:45 amAsheville Regional
5h 08m
1 stop
DSM10:53 amDes Moines
$274
United Airlines
Feb 24
DSM3:24 pmDes Moines
4h 18m
1 stop
GSO8:42 pmGreensboro/H. Point
Feb 28
GSO6:00 amGreensboro/H. Point
9h 27m
2 stops
DSM2:27 pmDes Moines
$284
United Airlines
Feb 24
DSM11:30 amDes Moines
8h 56m
2 stops
GSO9:26 pmGreensboro/H. Point
Feb 28
GSO6:00 amGreensboro/H. Point
9h 27m
2 stops
DSM2:27 pmDes Moines
$289

Frontier flights from Des Moines to North Carolina

Our best Frontier deals on Des Moines to North Carolina flight tickets
Frontier
Mar 10
DSM11:00 amDes Moines
9h 53m
1 stop
RDU9:53 pmRaleigh-Durham
Mar 11
RDU10:38 pmRaleigh-Durham
12h 07m
1 stop
DSM9:45 amDes Moines
$181
Frontier
Mar 10
DSM11:00 amDes Moines
9h 53m
1 stop
RDU9:53 pmRaleigh-Durham
Mar 12
RDU10:38 pmRaleigh-Durham
11h 52m
1 stop
DSM9:30 amDes Moines
$210
Frontier
Mar 10
DSM11:00 amDes Moines
9h 53m
1 stop
RDU9:53 pmRaleigh-Durham
Mar 14
RDU10:38 pmRaleigh-Durham
12h 07m
1 stop
DSM9:45 amDes Moines
$216

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Tue 3/10

11:00 am-9:53 pm

1 stop9h 53m

Raleigh-Durham

Wed 3/11

10:38 pm-9:45 am

1 stop12h 07m

$181

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Tue 3/10

11:00 am-9:53 pm

1 stop9h 53m

Raleigh-Durham

Thu 3/12

10:38 pm-9:30 am

1 stop11h 52m

$210

Des MoinesBlountville

DSM - TRI

DSMTRI

Des Moines

Sat 2/28

2:02 pm-8:03 pm

1 stop5h 01m

Blountville Tri Cities TN/VA

Tue 3/3

4:16 pm-11:48 pm

1 stop8h 32m

$254

Des MoinesBlountville

DSM - TRI

DSMTRI

Des Moines

Tue 2/24

2:00 pm-8:50 pm

1 stop5h 50m

Blountville Tri Cities TN/VA

Sat 2/28

5:30 am-10:44 am

1 stop6h 14m

$259

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Wed 6/24

5:45 am-1:49 pm

1 stop7h 04m

Greensboro/H. Point

Sun 6/28

6:55 pm-10:26 pm

1 stop4h 31m

$269

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Tue 4/14

2:44 pm-10:33 pm

1 stop6h 49m

Asheville Regional

Sat 4/18

5:43 am-11:05 am

1 stop6h 22m

$269

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 2/24

3:24 pm-8:42 pm

1 stop4h 18m

Greensboro/H. Point

Sat 2/28

6:00 am-2:27 pm

2 stops9h 27m

$284

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 2/24

11:30 am-9:26 pm

2 stops8h 56m

Greensboro/H. Point

Sat 2/28

6:00 am-2:27 pm

2 stops9h 27m

$289

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 3/9

4:20 pm-10:25 pm

1 stop5h 05m

Charlotte Douglas

Mon 3/16

8:00 am-12:10 pm

1 stop5h 10m

$292

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sat 5/2

6:40 am-3:20 pm

2 stops7h 40m

Knoxville McGhee Tyson

Tue 5/5

8:15 am-10:10 pm

2 stops14h 55m

$304

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to North Carolina from

How to get the cheapest flight ticket from Des Moines to North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to North Carolina?

If you don’t want to visit North Carolina in September, then you should wait until October to fly from Des Moines, when ticket prices are also cheap, with an average price of $328.

What is the cheapest Des Moines to North Carolina flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - North Carolina flight prices

How far in advance should I book a flight to North Carolina?

You are more likely to see cheaper flights to North Carolina from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to North Carolina for around $366 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to North Carolina from Des Moines for as low as $296 on momondo.

What cabin class options are available on Des Moines to North Carolina flights?

There are 3 cabin classes available to choose from on Des Moines to North Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to North Carolina flights?

You could potentially save up to 78% on your flight if you consider stops on a Des Moines to North Carolina flight.

Cheap Des Moines to North Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to North Carolina

Best Price Found

$235

Fastest flight time

2h 23m

Direct flights

Every day

Airports in North Carolina

110 airports
The best one-way flight to North Carolina from Des Moines in the past 72 hours is $235. The best round-trip flight deal from Des Moines to North Carolina found on momondo in the last 72 hours is $378.
The fastest flight from Des Moines to North Carolina takes 2h 23m
Direct flights go from Des Moines to North Carolina every day.
There are 110 airports in North Carolina. From Des Moines there are direct flights to Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to North Carolina?

    Prices for flights from Des Moines Airport to North Carolina refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to North Carolina?

  • How old do you have to be to fly from Des Moines Airport to North Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to North Carolina.

  • What documentation or ID do you need to fly to North Carolina?

    The necessary travel and health documents for your North Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Des Moines to North Carolina?

Best airlines flying from Des Moines to North Carolina

Compare and see reviews for airlines that fly from Des Moines to North Carolina with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $216Free CancellationRating
8.0
4,280 reviews
Search Southwest flights
DeltaPriceFrom $216Free CancellationRating
7.9
8,175 reviews
Search Delta flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,266 reviews
Search American Airlines flights
United AirlinesPriceFrom $276Free CancellationRating
7.4
9,274 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to North Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to North Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to North Carolina with flexible booking policies on momondo?

Yes. All flights to North Carolina from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to North Carolina?

momondo provides multiple filters to help you find the best flight to North Carolina from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to North Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to North Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your North Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 3/13
Fri 3/20
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to North Carolina

Popular cities in North Carolina

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $52
Flights to Los Angelesfrom $46
Flights to Miamifrom $43
Flights to Chicagofrom $50
Flights to Orlandofrom $52
Flights to San Franciscofrom $56
Flights to Las Vegasfrom $27
Flights to Washington, D.C.from $56
Flights to Bostonfrom $65
Flights to Atlantafrom $49
Flights to Dallasfrom $54
Flights to Seattlefrom $61