What airlines fly to North Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to North Carolina from Des Moines according to our data. American Airlines is the first choice among our users, with 74% of people opting to fly with this airline when traveling to North Carolina. Keep in mind that there are 4 different airlines that fly to North Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Des Moines to North Carolina on average per week?

10 flights are operational weekly from Des Moines to North Carolina as of April 2026. The most popular departure day for this route is Mon, with 20% of flights per week taking off on this day.

What is the cheapest airline that flies from Des Moines to North Carolina?

Allegiant Air, United Airlines, and Southwest are the most popular carriers operating from Des Moines to North Carolina

How many flights depart from Des Moines to North Carolina on average per day?

The number of flights available between Des Moines and North Carolina is 1 per day as of April 2026. The most frequent departure time is 7:00AM, with 50% of daily flights leaving at noon.

When did momondo last update prices for flights from Des Moines Airport to North Carolina?

Prices for flights from Des Moines Airport to North Carolina refresh daily.

How many operators does momondo search for flights from Des Moines Airport to North Carolina?

There are 4 operators available for flights from Des Moines Airport to North Carolina as of April 2026.

How old do you have to be to fly from Des Moines Airport to North Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to North Carolina.

What documentation or ID do you need to fly to North Carolina?

The necessary travel and health documents for your North Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$76 Cheap Flights from Des Moines to North Carolina in 2026

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Find the cheapest flights from Des Moines to North Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:04 pm - 4:56 pm

DSM

CLT

25h 52m

1 stop

5:20 pm - 1:31 pm

CLT

DSM

21h 11m

1 stop

$151Frontier

Fri, May 1 - Tue, May 5

2:04 pm - 4:56 pm

DSM

CLT

25h 52m

1 stop

5:20 pm - 1:31 pm

CLT

DSM

21h 11m

1 stop

$171Frontier

Fri, May 1 - Tue, May 5

11:23 am - 4:58 pm

DSM

AVL

4h 35m

1 stop

6:40 am - 10:27 am

AVL

DSM

4h 47m

1 stop

$275United Airlines

Wed, May 27 - Sat, May 30

4:48 pm - 11:09 pm

DSM

AVL

5h 21m

1 stop

5:00 am - 1:18 pm

AVL

DSM

9h 18m

2 stops

$280American Airlines

Tue, May 26 - Sat, May 30

5:00 am - 2:17 pm

DSM

AVL

8h 17m

2 stops

5:00 am - 1:18 pm

AVL

DSM

9h 18m

2 stops

$285American Airlines

Wed, May 27 - Sat, May 30

5:30 am - 10:30 am

DSM

RDU

4h 00m

1 stop

5:45 am - 1:20 pm

RDU

DSM

8h 35m

1 stop

$289Southwest

Wed, May 20 - Sat, May 23

3:21 pm - 11:08 pm

DSM

TYS

6h 47m

1 stop

5:55 pm - 11:24 pm

TYS

DSM

6h 29m

1 stop

$290United Airlines

Wed, Apr 29 - Wed, May 6

5:35 am - 10:40 am

DSM

RDU

4h 05m

1 stop

5:45 am - 1:20 pm

RDU

DSM

8h 35m

1 stop

$307Southwest

Sat, May 16 - Sat, May 23

6:39 pm - 11:59 pm

DSM

MYR

4h 20m

1 stop

4:16 pm - 10:31 pm

MYR

DSM

7h 15m

1 stop

$335Delta

Tue, Jun 9 - Tue, Jun 16

6:31 pm - 11:59 pm

DSM

ILM

4h 28m

1 stop

5:50 pm - 10:34 pm

ILM

DSM

5h 44m

1 stop

$355Delta

Wed, Apr 29 - Tue, May 5

Southwest flights from Des Moines to North Carolina

Our best Southwest deals on Des Moines to North Carolina flight tickets

Southwest

May 20

DSM5:30 amDes Moines

4h 00m

1 stop

RDU10:30 amRaleigh-Durham

May 23

RDU5:45 amRaleigh-Durham

8h 35m

1 stop

DSM1:20 pmDes Moines

$289

Southwest

May 16

DSM5:35 amDes Moines

4h 05m

1 stop

RDU10:40 amRaleigh-Durham

May 23

RDU5:45 amRaleigh-Durham

8h 35m

1 stop

DSM1:20 pmDes Moines

$307

Southwest

May 12

DSM5:30 amDes Moines

6h 15m

2 stops

RDU12:45 pmRaleigh-Durham

May 19

RDU6:40 pmRaleigh-Durham

4h 30m

1 stop

DSM10:10 pmDes Moines

$312

Delta flights from Des Moines to North Carolina

Our best Delta deals on Des Moines to North Carolina flight tickets

Delta

Jun 29

DSM6:39 pmDes Moines

4h 15m

1 stop

TYS11:54 pmKnoxville McGhee Tyson

Jul 7

TYS5:25 pmKnoxville McGhee Tyson

4h 24m

1 stop

DSM8:49 pmDes Moines

$334

Delta

Aug 18

DSM2:15 pmDes Moines

6h 17m

1 stop

ORF9:32 pmNorfolk

Aug 26

ORF5:00 pmNorfolk

4h 45m

1 stop

DSM8:45 pmDes Moines

$335

Delta

May 6

DSM5:45 pmDes Moines

4h 10m

1 stop

ORF10:55 pmNorfolk

May 9

ORF7:00 amNorfolk

7h 37m

1 stop

DSM1:37 pmDes Moines

$336

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 5/1

2:04 pm-4:56 pm

1 stop25h 52m

Charlotte Douglas

Tue 5/5

5:20 pm-1:31 pm

1 stop21h 11m

$151

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 5/1

2:04 pm-4:56 pm

1 stop25h 52m

Charlotte Douglas

Tue 5/5

5:20 pm-1:31 pm

1 stop21h 11m

$171

Quickest round-trip

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Wed 5/27

11:23 am-4:58 pm

1 stop4h 35m

Asheville Regional

Sat 5/30

6:40 am-10:27 am

1 stop4h 47m

$275

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Tue 5/26

4:48 pm-11:09 pm

1 stop5h 21m

Asheville Regional

Sat 5/30

5:00 am-1:18 pm

2 stops9h 18m

$280

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Wed 5/27

5:00 am-2:17 pm

2 stops8h 17m

Asheville Regional

Sat 5/30

5:00 am-1:18 pm

2 stops9h 18m

$285

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Wed 5/20

5:30 am-10:30 am

1 stop4h 00m

Raleigh-Durham

Sat 5/23

5:45 am-1:20 pm

1 stop8h 35m

$289

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 4/29

3:21 pm-11:08 pm

1 stop6h 47m

Knoxville McGhee Tyson

Wed 5/6

5:55 pm-11:24 pm

1 stop6h 29m

$290

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Sat 5/16

5:35 am-10:40 am

1 stop4h 05m

Raleigh-Durham

Sat 5/23

5:45 am-1:20 pm

1 stop8h 35m

$307

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 6/9

6:39 pm-11:59 pm

1 stop4h 20m

Myrtle Beach Intl

Tue 6/16

4:16 pm-10:31 pm

1 stop7h 15m

$335

Des MoinesWilmington

DSM - ILM

DSMILM

Des Moines

Wed 4/29

6:31 pm-11:59 pm

1 stop4h 28m

Wilmington New Hanover County

Tue 5/5

5:50 pm-10:34 pm

1 stop5h 44m

$355

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to North Carolina?

If you don’t want to visit North Carolina in September, then you should wait until October to fly from Des Moines, when ticket prices are also cheap, with an average price of $328.

What is the cheapest Des Moines to North Carolina flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - North Carolina flight prices

What cabin class options are available on Des Moines to North Carolina flights?

There are 3 cabin classes available to choose from on Des Moines to North Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to North Carolina flights?

You could potentially save up to 59% on your flight if you consider stops on a Des Moines to North Carolina flight.

Cheap Des Moines to North Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to North Carolina

Best Price Found	$233
Fastest flight time	2h 25m
Direct flights	Every day
Airports in North Carolina	110 airports

The best one-way flight to North Carolina from Des Moines in the past 72 hours is $233. The best round-trip flight deal from Des Moines to North Carolina found on momondo in the last 72 hours is $407.

The fastest flight from Des Moines to North Carolina takes 2h 25m

Direct flights go from Des Moines to North Carolina every day.

There are 110 airports in North Carolina. From Des Moines there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Des Moines to North Carolina

When did momondo last update prices for flights from Des Moines Airport to North Carolina?
Prices for flights from Des Moines Airport to North Carolina refresh daily.
How many operators does momondo search for flights from Des Moines Airport to North Carolina?
There are 4 operators available for flights from Des Moines Airport to North Carolina as of April 2026.
How old do you have to be to fly from Des Moines Airport to North Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to North Carolina.
What documentation or ID do you need to fly to North Carolina?
The necessary travel and health documents for your North Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Des Moines to North Carolina?
momondo data reveals that the most frequently booked plane model on the route from Des Moines to North Carolina is Airbus A320-100/200, representing 33.33% of all bookings. The subsequent popular models are Airbus A319 at 32.70%, Boeing 737 MAX 8 at 17.61%, and Canadair (Bombardier) Regional Jet 900 at 4.40%.

Best airlines flying from Des Moines to North Carolina

Compare and see reviews for airlines that fly from Des Moines to North Carolina with momondo

Airline	Rating	Free Cancellation	Price
Southwest	PriceFrom $216	Free Cancellation	Rating 8.0 4,336 reviews	Search Southwest flights
Delta	PriceFrom $228	Free Cancellation	Rating 7.9 8,369 reviews	Search Delta flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,549 reviews	Search American Airlines flights
United Airlines	PriceFrom $276	Free Cancellation	Rating 7.4 9,533 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to North Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to North Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to North Carolina with flexible booking policies on momondo?

Yes. All flights to North Carolina from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to North Carolina?

momondo provides multiple filters to help you find the best flight to North Carolina from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to North Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to North Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.