How many flights depart from Des Moines to North Carolina on average per week?

14 flights are operational weekly from Des Moines to North Carolina as of May 2026. The most popular departure day for this route is Mon, with 14% of flights per week taking off on this day.

How many flights depart from Des Moines to North Carolina on average per day?

The number of flights available between Des Moines and North Carolina is 2 per day as of May 2026. The most frequent departure time is 7:00AM, with 71% of daily flights leaving at noon.

What airlines fly to North Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to North Carolina from Des Moines according to our data. American Airlines is the first choice among our users, with 74% of people opting to fly with this airline when traveling to North Carolina. Keep in mind that there are 4 different airlines that fly to North Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to North Carolina?

Frontier, Allegiant Air, and United Airlines are the most popular carriers operating from Des Moines to North Carolina

When did momondo last update prices for flights from Des Moines Airport to North Carolina?

Prices for flights from Des Moines Airport to North Carolina refresh daily.

How many operators does momondo search for flights from Des Moines Airport to North Carolina?

There are 4 operators available for flights from Des Moines Airport to North Carolina as of May 2026.

How old do you have to be to fly from Des Moines Airport to North Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to North Carolina.

What documentation or ID do you need to fly to North Carolina?

The necessary travel and health documents for your North Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$126 Cheap Flights from Des Moines to North Carolina in 2026

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Find the cheapest flights from Des Moines to North Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:37 pm - 10:48 pm

DSM

TYS

8h 11m

1 stop

3:38 pm - 9:27 pm

TYS

DSM

6h 49m

1 stop

$213Allegiant Air

Mon, Jul 13 - Thu, Jul 16

5:02 pm - 9:50 pm

DSM

TYS

27h 48m

1 stop

3:46 pm - 10:52 pm

TYS

DSM

8h 06m

1 stop

$223Allegiant Air

Thu, Jun 4 - Sun, Jun 7

9:23 am - 8:50 pm

DSM

CLT

10h 27m

1 stop

10:45 pm - 12:12 am

CLT

DSM

2h 27mnonstop

$267American Airlines

Wed, Jun 10 - Wed, Jun 10

5:10 am - 10:55 am

DSM

CLT

4h 45m

1 stop

1:05 pm - 10:50 pm

CLT

DSM

10h 45m

2 stops

$274Southwest

Sat, Jun 6 - Sat, Jun 6

6:39 pm - 11:54 pm

DSM

TYS

4h 15m

1 stop

6:45 am - 10:14 am

TYS

DSM

4h 29m

1 stop

$307Delta

Wed, Jun 10 - Wed, Jun 17

3:45 pm - 9:10 pm

DSM

CLT

4h 25m

1 stop

4:00 pm - 11:30 pm

CLT

DSM

8h 30m

2 stops

$307Southwest

Wed, Jun 10 - Mon, Jun 15

7:56 pm - 8:07 am

DSM

CLT

11h 11m

1 stop

11:25 am - 12:49 pm

CLT

DSM

2h 24mnonstop

$309American Airlines

Sat, Sep 5 - Sun, Sep 6

5:35 am - 11:38 am

DSM

GSO

5h 03m

1 stop

4:35 pm - 10:31 pm

GSO

DSM

6h 56m

1 stop

$309Delta

Tue, Jun 23 - Tue, Jun 30

8:00 am - 1:29 pm

DSM

AVL

4h 29m

1 stop

6:55 am - 10:20 am

AVL

DSM

4h 25m

1 stop

$355United Airlines

Wed, Oct 28 - Sat, Oct 31

5:00 am - 3:32 pm

DSM

AVL

9h 32m

2 stops

6:55 am - 12:30 pm

AVL

DSM

6h 35m

1 stop

$360United Airlines

Wed, Oct 28 - Sat, Oct 31

Frontier flights from Des Moines to North Carolina

Our best Frontier deals on Des Moines to North Carolina flight tickets

Frontier

Jun 3

DSM2:16 pmDes Moines

27h 02m

1 stop

CLT6:18 pmCharlotte Douglas

Jun 7

CLT7:14 pmCharlotte Douglas

19h 17m

1 stop

DSM1:31 pmDes Moines

$300

Frontier

Jun 24

DSM2:16 pmDes Moines

20h 15m

1 stop

RDU11:31 amRaleigh-Durham

Jun 28

RDU12:26 pmRaleigh-Durham

26h 05m

1 stop

DSM1:31 pmDes Moines

$310

Frontier

Jun 3

DSM2:16 pmDes Moines

27h 02m

1 stop

CLT6:18 pmCharlotte Douglas

Jun 14

CLT7:14 pmCharlotte Douglas

19h 17m

1 stop

DSM1:31 pmDes Moines

$350

Southwest flights from Des Moines to North Carolina

Our best Southwest deals on Des Moines to North Carolina flight tickets

Southwest

Jun 6

DSM5:10 amDes Moines

4h 45m

1 stop

CLT10:55 amCharlotte Douglas

Jun 6

CLT1:05 pmCharlotte Douglas

10h 45m

2 stops

DSM10:50 pmDes Moines

$274

Southwest

Jun 30

DSM5:20 amDes Moines

6h 30m

2 stops

RDU12:50 pmRaleigh-Durham

Jul 1

RDU4:25 pmRaleigh-Durham

7h 20m

2 stops

DSM10:45 pmDes Moines

$301

Southwest

Jun 10

DSM3:45 pmDes Moines

4h 25m

1 stop

CLT9:10 pmCharlotte Douglas

Jun 15

CLT4:00 pmCharlotte Douglas

8h 30m

2 stops

DSM11:30 pmDes Moines

$307

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Mon 7/13

1:37 pm-10:48 pm

1 stop8h 11m

Knoxville McGhee Tyson

Thu 7/16

3:38 pm-9:27 pm

1 stop6h 49m

$213

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Thu 6/4

5:02 pm-9:50 pm

1 stop27h 48m

Knoxville McGhee Tyson

Sun 6/7

3:46 pm-10:52 pm

1 stop8h 06m

$223

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 6/10

9:23 am-8:50 pm

1 stop10h 27m

Charlotte Douglas

Wed 6/10

10:45 pm-12:12 am

Nonstop2h 27m

$267

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 6/6

5:10 am-10:55 am

1 stop4h 45m

Charlotte Douglas

Sat 6/6

1:05 pm-10:50 pm

2 stops10h 45m

$274

Quickest round-trip

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 6/10

6:39 pm-11:54 pm

1 stop4h 15m

Knoxville McGhee Tyson

Wed 6/17

6:45 am-10:14 am

1 stop4h 29m

$307

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 6/10

3:45 pm-9:10 pm

1 stop4h 25m

Charlotte Douglas

Mon 6/15

4:00 pm-11:30 pm

2 stops8h 30m

$307

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 9/5

7:56 pm-8:07 am

1 stop11h 11m

Charlotte Douglas

Sun 9/6

11:25 am-12:49 pm

Nonstop2h 24m

$309

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 6/23

5:35 am-11:38 am

1 stop5h 03m

Greensboro/H. Point

Tue 6/30

4:35 pm-10:31 pm

1 stop6h 56m

$309

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Wed 10/28

8:00 am-1:29 pm

1 stop4h 29m

Asheville Regional

Sat 10/31

6:55 am-10:20 am

1 stop4h 25m

$355

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Wed 10/28

5:00 am-3:32 pm

2 stops9h 32m

Asheville Regional

Sat 10/31

6:55 am-12:30 pm

1 stop6h 35m

$360

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to North Carolina?

If you don’t want to visit North Carolina in March, then you should wait until August to fly from Des Moines, when ticket prices are also cheap, with an average price of $158.

What is the cheapest Des Moines to North Carolina flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - North Carolina flight prices

What cabin class options are available on Des Moines to North Carolina flights?

There are 3 cabin classes available to choose from on Des Moines to North Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to North Carolina flights?

You could potentially save up to 51% on your flight if you consider stops on a Des Moines to North Carolina flight.

Cheap Des Moines to North Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to North Carolina

Best Price Found	$188
Fastest flight time	2h 26m
Direct flights	Every day
Airports in North Carolina	110 airports

The best one-way flight to North Carolina from Des Moines in the past 72 hours is $188. The best round-trip flight deal from Des Moines to North Carolina found on momondo in the last 72 hours is $413.

The fastest flight from Des Moines to North Carolina takes 2h 26m

Direct flights go from Des Moines to North Carolina every day.

There are 110 airports in North Carolina. From Des Moines there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Des Moines to North Carolina

When did momondo last update prices for flights from Des Moines Airport to North Carolina?
Prices for flights from Des Moines Airport to North Carolina refresh daily.
How many operators does momondo search for flights from Des Moines Airport to North Carolina?
There are 4 operators available for flights from Des Moines Airport to North Carolina as of May 2026.
How old do you have to be to fly from Des Moines Airport to North Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to North Carolina.
What documentation or ID do you need to fly to North Carolina?
The necessary travel and health documents for your North Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Des Moines to North Carolina?
momondo data reveals that the most frequently booked plane model on the route from Des Moines to North Carolina is Airbus A320-100/200, representing 37.60% of all bookings. The subsequent popular models are Airbus A319 at 22.40%, Boeing 737 MAX 8 at 18.40%, and Embraer 175 at 7.20%.

Best airlines flying from Des Moines to North Carolina

Compare and see reviews for airlines that fly from Des Moines to North Carolina with momondo

Airline	Rating	Free Cancellation	Price
Southwest	PriceFrom $216	Free Cancellation	Rating 7.9 4,272 reviews	Search Southwest flights
Delta	PriceFrom $236	Free Cancellation	Rating 7.9 8,436 reviews	Search Delta flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,631 reviews	Search American Airlines flights
United Airlines	PriceFrom $268	Free Cancellation	Rating 7.4 9,749 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to North Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to North Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to North Carolina with flexible booking policies on momondo?

Yes. All flights to North Carolina from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to North Carolina?

momondo provides multiple filters to help you find the best flight to North Carolina from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to North Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to North Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.