How many flights depart from Des Moines to North Carolina on average per week?

12 flights are operational weekly from Des Moines to North Carolina as of September 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.

What is the cheapest airline that flies from Des Moines to North Carolina?

Southwest, United Airlines, and Delta are the most popular carriers operating from Des Moines to North Carolina

What airlines fly to North Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to North Carolina from Des Moines according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to North Carolina. Keep in mind that there are 4 different airlines that fly to North Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Des Moines to North Carolina on average per day?

The number of flights available between Des Moines and North Carolina is 1 per day as of September 2026. The most frequent departure time is 8:00AM, with 50% of daily flights leaving at noon.

When did momondo last update prices for flights from Des Moines Airport to North Carolina?

Prices for flights from Des Moines Airport to North Carolina refresh daily.

How many operators does momondo search for flights from Des Moines Airport to North Carolina?

There are 4 operators available for flights from Des Moines Airport to North Carolina as of September 2026.

How old do you have to be to fly from Des Moines Airport to North Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to North Carolina.

What documentation or ID do you need to fly to North Carolina?

The necessary travel and health documents for your North Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$136 Cheap Flights from Des Moines to North Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to North Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 9:10 amDSM Des Moines-RDU Raleigh-Durham

24h 10m1 stop Philadelphia

12:00 pm - 2:42 pmRDU Raleigh-Durham-DSM Des Moines

27h 42m1 stop Philadelphia

$261Multiple Airlines

Sun, Oct 25 - Wed, Oct 28

6:37 pm - 12:21 pmDSM Des Moines-RDU Raleigh-Durham

16h 44m2 stops Fort Lauderdale Atlanta Hartsfield-Jackson

12:00 pm - 2:42 pmRDU Raleigh-Durham-DSM Des Moines

27h 42m1 stop Philadelphia

$274Multiple Airlines

Sun, Oct 25 - Wed, Oct 28

3:10 pm - 9:15 pmDSM Des Moines-CLT Charlotte Douglas

5h 05m1 stop Chicago Midway

6:05 pm - 10:15 pmCLT Charlotte Douglas-DSM Des Moines

5h 10m1 stop Chicago Midway

$317Southwest

Thu, Jan 14 - Mon, Jan 18

1:20 pm - 7:10 pmDSM Des Moines-CLT Charlotte Douglas

4h 50m1 stop Chicago Midway

7:25 am - 11:30 amCLT Charlotte Douglas-DSM Des Moines

5h 05m1 stop Chicago Midway

$317Southwest

Sat, Oct 24 - Tue, Oct 27

4:12 pm - 10:46 pmDSM Des Moines-AVL Asheville Regional

5h 34m1 stop Dallas/Fort Worth

7:45 pm - 11:58 pmAVL Asheville Regional-DSM Des Moines

5h 13m1 stop Charlotte Douglas

$322American Airlines

Sat, Oct 17 - Sat, Oct 24

7:08 am - 2:10 pmDSM Des Moines-AVL Asheville Regional

6h 02m1 stop Charlotte Douglas

7:59 pm - 11:57 pmAVL Asheville Regional-DSM Des Moines

4h 58m1 stop Charlotte Douglas

$322American Airlines

Sat, Oct 31 - Sun, Nov 15

3:03 pm - 10:15 pmDSM Des Moines-AVL Asheville Regional

6h 12m1 stop Atlanta Hartsfield-Jackson

2:03 pm - 6:09 pmAVL Asheville Regional-DSM Des Moines

5h 06m1 stop Atlanta Hartsfield-Jackson

$322Delta

Tue, Oct 20 - Tue, Oct 27

5:29 pm - 11:44 pmDSM Des Moines-RDU Raleigh-Durham

5h 15m1 stop Detroit Metropolitan Wayne County

12:52 pm - 4:49 pmRDU Raleigh-Durham-DSM Des Moines

4h 57m1 stop Detroit Metropolitan Wayne County

$325Delta

Sat, Dec 5 - Mon, Dec 7

8:00 am - 4:03 pmDSM Des Moines-RDU Raleigh-Durham

7h 03m1 stop Chicago O'Hare Intl

4:45 pm - 9:23 pmRDU Raleigh-Durham-DSM Des Moines

5h 38m1 stop Chicago O'Hare Intl

$325United Airlines

Thu, Oct 22 - Sat, Oct 24

3:11 pm - 9:46 pmDSM Des Moines-RDU Raleigh-Durham

5h 35m1 stop Chicago O'Hare Intl

6:05 am - 10:31 amRDU Raleigh-Durham-DSM Des Moines

5h 26m1 stop Chicago O'Hare Intl

$325United Airlines

Mon, Oct 19 - Tue, Oct 20

Cheap last minute flights

Enter your travel dates to find the best prices.

11:29 am - 6:59 pmDSM Des Moines-CLT Charlotte Douglas

6h 30m1 stop Denver Intl

7:54 pm - 7:33 pmCLT Charlotte Douglas-DSM Des Moines

24h 39m1 stop Denver Intl

$389Frontier

Thu, Sep 24 - Sun, Sep 27

5:40 am - 11:45 amDSM Des Moines-CLT Charlotte Douglas

5h 05m1 stop Chicago Midway

7:25 am - 11:30 amCLT Charlotte Douglas-DSM Des Moines

5h 05m1 stop Chicago Midway

$392Southwest

Sun, Sep 27 - Wed, Oct 14

5:40 am - 4:00 pmDSM Des Moines-CLT Charlotte Douglas

9h 20m2 stops Chicago Midway Nashville Intl

7:25 am - 11:30 amCLT Charlotte Douglas-DSM Des Moines

5h 05m1 stop Chicago Midway

$397Southwest

Sun, Sep 27 - Wed, Oct 14

11:29 am - 6:59 pmDSM Des Moines-CLT Charlotte Douglas

6h 30m1 stop Denver Intl

7:54 pm - 7:33 pmCLT Charlotte Douglas-DSM Des Moines

24h 39m1 stop Denver Intl

$399Frontier

Thu, Sep 24 - Sun, Sep 27

11:31 am - 7:45 pmDSM Des Moines-GSO Greensboro/H. Point

7h 14m1 stop Atlanta Hartsfield-Jackson

4:27 pm - 10:26 pmGSO Greensboro/H. Point-DSM Des Moines

6h 59m1 stop Atlanta Hartsfield-Jackson

$444Delta

Thu, Sep 24 - Mon, Sep 28

11:31 am - 7:45 pmDSM Des Moines-GSO Greensboro/H. Point

7h 14m1 stop Atlanta Hartsfield-Jackson

4:27 pm - 10:26 pmGSO Greensboro/H. Point-DSM Des Moines

6h 59m1 stop Atlanta Hartsfield-Jackson

$459Delta

Thu, Sep 24 - Mon, Sep 28

4:14 pm - 11:07 pmDSM Des Moines-AVL Asheville Regional

5h 53m1 stop Dallas/Fort Worth

7:45 pm - 11:58 pmAVL Asheville Regional-DSM Des Moines

5h 13m1 stop Charlotte Douglas

$476American Airlines

Mon, Sep 28 - Mon, Oct 12

7:00 am - 10:22 amDSM Des Moines-CLT Charlotte Douglas

2h 22mnonstop

10:50 pm - 8:56 amCLT Charlotte Douglas-DSM Des Moines

11h 06m1 stop Chicago O'Hare Intl

$524American Airlines

Sun, Sep 27 - Wed, Oct 14

6:00 am - 2:14 pmDSM Des Moines-GSO Greensboro/H. Point

7h 14m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:30 am - 10:31 amGSO Greensboro/H. Point-DSM Des Moines

5h 01m1 stop Chicago O'Hare Intl

$549United Airlines

Thu, Sep 24 - Mon, Sep 28

11:36 am - 5:08 pmDSM Des Moines-GSO Greensboro/H. Point

4h 32m1 stop Chicago O'Hare Intl

2:55 pm - 11:35 pmGSO Greensboro/H. Point-DSM Des Moines

9h 40m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$549United Airlines

Thu, Sep 24 - Mon, Sep 28

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American Airlines flights from Des Moines to North Carolina

Our best American Airlines deals on Des Moines to North Carolina flight tickets

American Airlines

Oct 17

DSM4:12 pmDes Moines

5h 34m

1 stop

AVL10:46 pmAsheville Regional

Oct 24

AVL7:45 pmAsheville Regional

5h 13m

1 stop

DSM11:58 pmDes Moines

$322

American Airlines

Oct 17

DSM3:01 pmDes Moines

7h 57m

2 stops

AVL11:58 pmAsheville Regional

Oct 24

AVL7:45 pmAsheville Regional

5h 13m

1 stop

DSM11:58 pmDes Moines

$365

American Airlines

Oct 6

DSM2:01 pmDes Moines

6h 53m

1 stop

AVL9:54 pmAsheville Regional

Oct 10

AVL7:00 amAsheville Regional

4h 40m

1 stop

DSM10:40 amDes Moines

$369

Southwest flights from Des Moines to North Carolina

Our best Southwest deals on Des Moines to North Carolina flight tickets

Southwest

Oct 24

DSM1:20 pmDes Moines

4h 50m

1 stop

CLT7:10 pmCharlotte Douglas

Oct 27

CLT7:25 amCharlotte Douglas

5h 05m

1 stop

DSM11:30 amDes Moines

$317

Southwest

Oct 24

DSM5:50 amDes Moines

4h 05m

1 stop

CLT10:55 amCharlotte Douglas

Oct 27

CLT11:15 amCharlotte Douglas

10h 25m

2 stops

DSM8:40 pmDes Moines

$322

Southwest

Oct 24

DSM5:50 amDes Moines

6h 15m

2 stops

CLT1:05 pmCharlotte Douglas

Oct 27

CLT7:25 amCharlotte Douglas

11h 25m

2 stops

DSM5:50 pmDes Moines

$327

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRaleigh

DSM Des Moines - RDU Raleigh-Durham

DSMRDU

Des Moines

Sun 10/25

8:00 am-9:10 am

1 stop24h 10m

Raleigh-Durham

Wed 10/28

12:00 pm-2:42 pm

1 stop27h 42m

$261

Des MoinesRaleigh

DSM Des Moines - RDU Raleigh-Durham

DSMRDU

Des Moines

Sun 10/25

6:37 pm-12:21 pm

2 stops16h 44m

Raleigh-Durham

Wed 10/28

12:00 pm-2:42 pm

1 stop27h 42m

$274

Des MoinesCharlotte

DSM Des Moines - CLT Charlotte Douglas

DSMCLT

Des Moines

Thu 1/14

3:10 pm-9:15 pm

1 stop5h 05m

Charlotte Douglas

Mon 1/18

6:05 pm-10:15 pm

1 stop5h 10m

$317

Quickest round-trip

Des MoinesCharlotte

DSM Des Moines - CLT Charlotte Douglas

DSMCLT

Des Moines

Sat 10/24

1:20 pm-7:10 pm

1 stop4h 50m

Charlotte Douglas

Tue 10/27

7:25 am-11:30 am

1 stop5h 05m

$317

Des MoinesAsheville

DSM Des Moines - AVL Asheville Regional

DSMAVL

Des Moines

Sat 10/17

4:12 pm-10:46 pm

1 stop5h 34m

Asheville Regional

Sat 10/24

7:45 pm-11:58 pm

1 stop5h 13m

$322

Des MoinesAsheville

DSM Des Moines - AVL Asheville Regional

DSMAVL

Des Moines

Sat 10/31

7:08 am-2:10 pm

1 stop6h 02m

Asheville Regional

Sun 11/15

7:59 pm-11:57 pm

1 stop4h 58m

$322

Des MoinesAsheville

DSM Des Moines - AVL Asheville Regional

DSMAVL

Des Moines

Tue 10/20

3:03 pm-10:15 pm

1 stop6h 12m

Asheville Regional

Tue 10/27

2:03 pm-6:09 pm

1 stop5h 06m

$322

Des MoinesRaleigh

DSM Des Moines - RDU Raleigh-Durham

DSMRDU

Des Moines

Sat 12/5

5:29 pm-11:44 pm

1 stop5h 15m

Raleigh-Durham

Mon 12/7

12:52 pm-4:49 pm

1 stop4h 57m

$325

Des MoinesRaleigh

DSM Des Moines - RDU Raleigh-Durham

DSMRDU

Des Moines

Thu 10/22

8:00 am-4:03 pm

1 stop7h 03m

Raleigh-Durham

Sat 10/24

4:45 pm-9:23 pm

1 stop5h 38m

$325

Des MoinesRaleigh

DSM Des Moines - RDU Raleigh-Durham

DSMRDU

Des Moines

Mon 10/19

3:11 pm-9:46 pm

1 stop5h 35m

Raleigh-Durham

Tue 10/20

6:05 am-10:31 am

1 stop5h 26m

$325

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to North Carolina?

If you don’t want to visit North Carolina in June, then you should wait until August to fly from Des Moines, when ticket prices are also cheap, with an average price of $383.

What is the cheapest Des Moines to North Carolina flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - North Carolina flight prices

What cabin class options are available on Des Moines to North Carolina flights?

There are 4 cabin classes available to choose from on Des Moines to North Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to North Carolina flights?

You could potentially save up to 54% on your flight if you consider stops on a Des Moines to North Carolina flight.

Cheap Des Moines to North Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to North Carolina

Best Price Found	$136
Fastest flight time	2h 22m
Direct flights	Every day
Airports in North Carolina	110 airports

The best one-way flight to North Carolina from Des Moines in the past 72 hours is $136. The best round-trip flight deal from Des Moines to North Carolina found on momondo in the last 72 hours is $261.

The fastest flight from Des Moines to North Carolina takes 2h 22m

Direct flights go from Des Moines to North Carolina every day.

There are 110 airports in North Carolina. From Des Moines there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Des Moines to North Carolina

When did momondo last update prices for flights from Des Moines Airport to North Carolina?
Prices for flights from Des Moines Airport to North Carolina refresh daily.
How many operators does momondo search for flights from Des Moines Airport to North Carolina?
There are 4 operators available for flights from Des Moines Airport to North Carolina as of September 2026.
How old do you have to be to fly from Des Moines Airport to North Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to North Carolina.
What documentation or ID do you need to fly to North Carolina?
The necessary travel and health documents for your North Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Des Moines to North Carolina?
momondo data reveals that the most frequently booked plane model on the route from Des Moines to North Carolina is Airbus A320-100/200, representing 32.38% of all bookings. The subsequent popular models are Airbus A319 at 23.81%, Boeing 737 MAX 8 at 21.90%, and Canadair (Bombardier) Regional Jet 900 at 6.67%.

Best airlines flying from Des Moines to North Carolina

Compare and see reviews for airlines that fly from Des Moines to North Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $236	Free Cancellation	Rating 7.8 8,591 reviews	Search Delta flights
United Airlines	PriceFrom $254	Free Cancellation	Rating 7.4 10,226 reviews	Search United Airlines flights
American Airlines	PriceFrom $269	Free Cancellation	Rating 7.0 12,076 reviews	Search American Airlines flights
Southwest	PriceFrom $309	Free Cancellation	Rating 8.0 4,198 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to North Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to North Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to North Carolina with flexible booking policies on momondo?

Yes. All flights to North Carolina from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to North Carolina?

momondo provides multiple filters to help you find the best flight to North Carolina from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to North Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to North Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.