What is the cheapest airline that flies from Des Moines to Harrisburg?

Allegiant Air, United Airlines, and American Airlines are the most popular carriers operating from Des Moines to Harrisburg

Which layover airport has the shortest travel time from Des Moines to Harrisburg?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 4h 34m.

What airlines fly to Harrisburg?

Delta, United Airlines and American Airlines are the top three most popular airlines that fly to Harrisburg from Des Moines according to our data. Delta is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Harrisburg. Keep in mind that there are 3 different airlines that fly to Harrisburg on a routine basis, so you have a few additional options to choose from.

Which layover airport offers the lowest fares from Des Moines to Harrisburg?

Flights via Chicago (ORD) offer the lowest average round-trip price of $443.

Which layover airport has the shortest connection time from Des Moines to Harrisburg?

Detroit (DTW) has the shortest average layover time for this route: 1h 02m.

Which airport is the most popular layover for flights between Des Moines and Harrisburg?

Chicago (ORD) was the most common stop: 86% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from Des Moines Airport to Harrisburg Airport?

Prices for flights from Des Moines Airport to Harrisburg Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Harrisburg Airport?

The number of operators available for flights from Des Moines Airport to Harrisburg Airport is 3 as of November 2026.

How old do you have to be to fly from Des Moines Airport to Harrisburg Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Harrisburg Airport.

What documentation or ID do you need to fly to Harrisburg Airport?

The travel and health documents you'll need for your trip to Harrisburg Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Harrisburg Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$245 Cheap Flights from Des Moines to Harrisburg in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Harrisburg

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:29 pm - 11:10 pmDSM Des Moines-MDT Harrisburg

4h 41m1 stop Detroit Metropolitan Wayne County

6:00 am - 10:53 amMDT Harrisburg-DSM Des Moines

5h 53m1 stop Atlanta Hartsfield-Jackson

$339Delta

Fri, Dec 4 - Sun, Dec 6

1:05 pm - 7:25 pmDSM Des Moines-MDT Harrisburg

5h 20m1 stop Chicago O'Hare Intl

6:07 am - 10:47 amMDT Harrisburg-DSM Des Moines

5h 40m1 stop Chicago O'Hare Intl

$339United Airlines

Wed, Feb 17 - Tue, Feb 23

8:50 am - 6:48 pmDSM Des Moines-MDT Harrisburg

8h 58m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

5:40 pm - 9:26 pmMDT Harrisburg-DSM Des Moines

4h 46m1 stop Chicago O'Hare Intl

$344United Airlines

Wed, Feb 17 - Tue, Feb 23

6:10 am - 2:03 pmDSM Des Moines-MDT Harrisburg

6h 53m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:20 am - 12:30 pmMDT Harrisburg-DSM Des Moines

7h 10m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$349United Airlines

Wed, Feb 17 - Tue, Feb 23

3:20 pm - 8:54 pmDSM Des Moines-MDT Harrisburg

4h 34m1 stop Chicago O'Hare Intl

2:50 pm - 11:15 pmMDT Harrisburg-DSM Des Moines

9h 25m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$412United Airlines

Fri, Dec 4 - Sun, Dec 6

12:52 pm - 7:11 pmDSM Des Moines-MDT Harrisburg

5h 19m1 stop Chicago O'Hare Intl

5:40 pm - 9:37 pmMDT Harrisburg-DSM Des Moines

4h 57m1 stop Chicago O'Hare Intl

$439United Airlines

Sat, Jan 23 - Wed, Jan 27

2:59 pm - 11:50 pmDSM Des Moines-MDT Harrisburg

7h 51m1 stop Atlanta Hartsfield-Jackson

12:09 pm - 4:49 pmMDT Harrisburg-DSM Des Moines

5h 40m1 stop Detroit Metropolitan Wayne County

$598Delta

Wed, Nov 25 - Sun, Nov 29

1:58 pm - 10:17 pmDSM Des Moines-MDT Harrisburg

7h 19m1 stop Chicago O'Hare Intl

2:15 pm - 12:19 amMDT Harrisburg-DSM Des Moines

11h 04m1 stop Chicago O'Hare Intl

$723American Airlines

Wed, Nov 25 - Sun, Nov 29

1:58 pm - 7:25 pmDSM Des Moines-MDT Harrisburg

4h 27m1 stop Chicago O'Hare Intl

7:55 pm - 12:19 amMDT Harrisburg-DSM Des Moines

5h 24m1 stop Chicago O'Hare Intl

$729American Airlines

Wed, Nov 25 - Sun, Nov 29

3:05 pm - 11:57 amDSM Des Moines-MDT Harrisburg

19h 52m1 stop Punta Gorda

9:17 pm - 8:04 pmMDT Harrisburg-DSM Des Moines

23h 47m1 stop Orlando Sanford Intl

$761Allegiant Air

Wed, Nov 25 - Sun, Nov 29

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Delta flights from Des Moines to Harrisburg

Our best Delta deals on Des Moines to Harrisburg flight tickets

Delta

Dec 4

DSM5:29 pmDes Moines

4h 41m

1 stop

MDT11:10 pmHarrisburg

Dec 6

MDT6:00 amHarrisburg

5h 53m

1 stop

DSM10:53 amDes Moines

$339

Delta

Nov 11

DSM11:36 amDes Moines

5h 01m

1 stop

MDT5:37 pmHarrisburg

Nov 14

MDT6:00 amHarrisburg

4h 46m

1 stop

DSM9:46 amDes Moines

$369

Delta

Nov 25

DSM2:59 pmDes Moines

7h 51m

1 stop

MDT11:50 pmHarrisburg

Nov 29

MDT12:09 pmHarrisburg

5h 40m

1 stop

DSM4:49 pmDes Moines

$598

United Airlines flights from Des Moines to Harrisburg

Our best United Airlines deals on Des Moines to Harrisburg flight tickets

United Airlines

Feb 17

DSM8:50 amDes Moines

8h 58m

2 stops

MDT6:48 pmHarrisburg

Feb 23

MDT5:40 pmHarrisburg

4h 46m

1 stop

DSM9:26 pmDes Moines

$344

United Airlines

Feb 17

DSM6:10 amDes Moines

6h 53m

2 stops

MDT2:03 pmHarrisburg

Feb 23

MDT6:20 amHarrisburg

7h 10m

2 stops

DSM12:30 pmDes Moines

$349

United Airlines

Nov 11

DSM8:00 amDes Moines

9h 36m

2 stops

MDT6:36 pmHarrisburg

Nov 14

MDT8:15 amHarrisburg

5h 05m

1 stop

DSM12:20 pmDes Moines

$374

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Fri 12/4

5:29 pm-11:10 pm

1 stop4h 41m

Harrisburg

Sun 12/6

6:00 am-10:53 am

1 stop5h 53m

$339

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Wed 2/17

1:05 pm-7:25 pm

1 stop5h 20m

Harrisburg

Tue 2/23

6:07 am-10:47 am

1 stop5h 40m

$339

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Wed 2/17

8:50 am-6:48 pm

2 stops8h 58m

Harrisburg

Tue 2/23

5:40 pm-9:26 pm

1 stop4h 46m

$344

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Wed 2/17

6:10 am-2:03 pm

2 stops6h 53m

Harrisburg

Tue 2/23

6:20 am-12:30 pm

2 stops7h 10m

$349

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Fri 12/4

3:20 pm-8:54 pm

1 stop4h 34m

Harrisburg

Sun 12/6

2:50 pm-11:15 pm

2 stops9h 25m

$412

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Sat 1/23

12:52 pm-7:11 pm

1 stop5h 19m

Harrisburg

Wed 1/27

5:40 pm-9:37 pm

1 stop4h 57m

$439

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Wed 11/25

2:59 pm-11:50 pm

1 stop7h 51m

Harrisburg

Sun 11/29

12:09 pm-4:49 pm

1 stop5h 40m

$598

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Wed 11/25

1:58 pm-10:17 pm

1 stop7h 19m

Harrisburg

Sun 11/29

2:15 pm-12:19 am

1 stop11h 04m

$723

Quickest round-trip

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Wed 11/25

1:58 pm-7:25 pm

1 stop4h 27m

Harrisburg

Sun 11/29

7:55 pm-12:19 am

1 stop5h 24m

$729

Des MoinesHarrisburg

DSM Des Moines - MDT Harrisburg

DSMMDT

Des Moines

Wed 11/25

3:05 pm-11:57 am

1 stop19h 52m

Harrisburg

Sun 11/29

9:17 pm-8:04 pm

1 stop23h 47m

$761

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Harrisburg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Des Moines and Harrisburg?

Prices are currently typical for flights on this route.

Typical prices usually range from $338 to $409.
The lowest price recently found on this route was $339.

What is the cheapest month to fly to Harrisburg?

The month of December is, on average, the cheapest month to fly to Harrisburg from Des Moines, with most prices found around $357. If you aren’t able to travel to Harrisburg during the month of December, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $368.

When to book flights from Des Moines to Harrisburg

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Harrisburg according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Harrisburg (DSM to MDT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Harrisburg

Best Price Found	$245
Fastest flight time	4h 41m
Direct flights	None

The best one-way flight to Harrisburg from Des Moines in the past 72 hours is $245. The best round-trip flight deal from Des Moines to Harrisburg found on momondo in the last 72 hours is $339.

The fastest flight from Des Moines to Harrisburg takes 4h 41m

There are no direct flights from Des Moines to Harrisburg. There are no popular flight routes from Des Moines to Harrisburg.

Search flight deals

Frequently asked questions about flying from Des Moines to Harrisburg

How far is Des Moines to Harrisburg by plane?
The straight-line distance from Des Moines to Harrisburg is 876.7 mi. Flights usually cover this in 4h 41m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Des Moines Airport to Harrisburg Airport?
Prices for flights from Des Moines Airport to Harrisburg Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Harrisburg Airport?
The number of operators available for flights from Des Moines Airport to Harrisburg Airport is 3 as of November 2026.
How old do you have to be to fly from Des Moines Airport to Harrisburg Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Harrisburg Airport.
What documentation or ID do you need to fly to Harrisburg Airport?
The travel and health documents you'll need for your trip to Harrisburg Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Harrisburg Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Harrisburg?
momondo data reveals that the most frequently booked airline on the route from Des Moines to Harrisburg is United Airlines, representing 49% of all bookings. The subsequent popular airlines are American Airlines at 37% and Delta at 14%.

Best airlines flying from Des Moines to Harrisburg

Compare and see reviews for airlines that fly from Des Moines to Harrisburg with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $268	Free Cancellation	Rating 7.8 8,696 reviews	Search Delta flights
American Airlines	PriceFrom $274	Free Cancellation	Rating 7.0 12,212 reviews	Search American Airlines flights
United Airlines	PriceFrom $349	Free Cancellation	Rating 7.3 10,462 reviews	Search United Airlines flights

Hershey

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Mechanicsburg

Camp Hill

Hummelstown

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Harrisburg?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Harrisburg from Des Moines.

Can I find flights from Des Moines to Harrisburg with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Harrisburg flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Harrisburg?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Harrisburg from Des Moines.

I’m not ready to book a flight from Des Moines to Harrisburg right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Harrisburg flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.