Cheap flights from Des Moines to Detroit from $122

The cheapest month to fly to Detroit from Des Moines is in May. Flight prices, which tend to average around $399, are often lower during this time because this is during the off-season. If you’re not able to fly to Detroit in May, then December is your next best option. Flight prices from Des Moines to Detroit during December average around $405.

On average, the least expensive day to fly to Detroit from Des Moines is on a Friday. momondo users have found tickets for Friday departures for as low as $455. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to Detroit for around $619.

In the morning is the cheapest time of day to fly from Des Moines to Detroit when you can find flight prices for as low as $503. Flying to Detroit in the morning is an ideal time because this is during off-peak travel hours. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,609 on average. Flights to Detroit from Des Moines at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Des Moines to Detroit Metropolitan Wayne County for the best Des Moines - Detroit flight prices

There are 4 cabin classes available to choose from on Des Moines to Detroit flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 14% on your flight if you consider stops on a Des Moines to Detroit flight.

Historically, on average around 11% of flights between Des Moines and Detroit have experienced a delay on any given week. The average delay length over the past 12 months has been 143 minutes.

Generally, flights departing in the evening tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, Delta have had the least number of delays on this route over the last 12 months; with about 11% of their flights experiencing any sort of delay.

The number of flights available between Des Moines and Detroit is 5 per day as of October 2026. The most frequent departure time is 10:00AM, with 63% of daily flights leaving at noon.

As of October 2026, 39 flights take off from Des Moines and land in Detroit each week. The most common flight departure day for this route is Thu, with 33% of weekly flights taking off on this day.