Cheap flights from Des Moines to Charleston from $109
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Charleston departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from Des Moines to Charleston
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
American Airlines flights from Des Moines to Charleston
Our best American Airlines deals on Des Moines to Charleston flight tickets
Delta flights from Des Moines to Charleston
Our best Delta deals on Des Moines to Charleston flight tickets
See travel insights to Charleston from
How to get the cheapest flight ticket from Des Moines to Charleston
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Charleston?
The cheapest month to fly to Charleston from Des Moines is in May. Flight prices, which tend to average around $341, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Charleston, with average flight prices from Des Moines averaging around $343.
What is the cheapest day to depart on your flight to Charleston?
The cheapest day to depart from Des Moines to Charleston is on a Monday. Travelers who choose to depart for Charleston on a Monday will often find tickets for as low as $379. The most expensive day to fly to Charleston is Thursday, with ticket prices averaging around $508.
What is the cheapest time of day to depart on your flight to Charleston?
The cheapest time of day to fly to Charleston is in the afternoon when flights can be purchased for as low as $386. In the morning is when there is more demand to fly to Charleston, so prices are often more expensive at around $405 per ticket.
How far in advance should I book a flight to Charleston?
You are more likely to see cheaper flights to Charleston from Des Moines when booking 10 weeks ahead of your departure date. In general, you can expect to find flights to Charleston for around $393 when searching 10 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charleston from Des Moines for as low as $314 on momondo.
What is the cheapest airline that flies from Des Moines to Charleston?
American Airlines and United Airlines are the most popular carriers operating from Des Moines to Charleston
What airlines fly to Charleston?
American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Charleston from Des Moines according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Charleston. Keep in mind that there are 4 different airlines that fly to Charleston on a routine basis, so you have a few additional options to choose from.
When to book flights from Des Moines to Charleston
Cheap Des Moines to Charleston (DSM to CHS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Des Moines to Charleston
How far is Des Moines to Charleston by plane?
The distance between Des Moines and Charleston is about 966.2 mi. Flights usually cover this in 4h 31m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Des Moines Airport to Charleston Airport?
Prices for flights from Des Moines Airport to Charleston Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Charleston Airport?
There are 3 operators available for flights from Des Moines Airport to Charleston Airport as of June 2025.
How old do you have to be to fly from Des Moines Airport to Charleston Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Charleston Airport.
What documentation or ID do you need to fly to Charleston Airport?
The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Des Moines to Charleston?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Des Moines to Charleston is American Airlines (62% of total bookings). The next most popular airlines are Delta (33%) and United Airlines (4%).
Best airlines flying from Des Moines to Charleston
Compare and see reviews for airlines that fly from Des Moines to Charleston with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $237 | Free Cancellation | Rating 8.0 7,963 reviews | |||
| PriceFrom $264 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $315 | Free Cancellation | Rating 7.4 8,801 reviews |
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Des Moines to Charleston?
momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Charleston. momondo saves you time and could save you money on your trip.
Can I find flights from Des Moines to Charleston with flexible booking policies on momondo?
Yes. momondo allows you to filter the results for Des Moines to Charleston flights to just show those with flexible booking policies.
How can momondo help me find flights from Des Moines to Charleston?
momondo helps you find the best flight between Des Moines and Charleston by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.
I’m not ready to book a flight from Des Moines to Charleston right now. Can momondo alert me if prices change?
Yes. momondo can track prices for Des Moines to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.