Cheap flights from Des Moines to Cape Cod and the Islands from $484

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Cape Cod and the Islands departing on 8/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Des Moines to Cape Cod and the Islands

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:40 am - 12:00 pm
DSM
-
MVY
5h 20m
1 stop
American Airlines Logo
5:25 pm - 11:44 pm
MVY
-
DSM
7h 19m
1 stop
$484American Airlines
Thu, Aug 6 - Thu, Aug 13
American Airlines Logo
5:40 am - 2:30 pm
DSM
-
MVY
7h 50m
1 stop
American Airlines Logo
12:30 pm - 8:25 pm
MVY
-
DSM
8h 55m
2 stops
$586American Airlines
Thu, Aug 6 - Thu, Aug 13
American Airlines Logo
7:49 pm - 12:00 pm
DSM
-
MVY
15h 11m
2 stops
American Airlines Logo
12:30 pm - 8:25 pm
MVY
-
DSM
8h 55m
2 stops
$696American Airlines
Thu, Aug 6 - Thu, Aug 13
Multiple Airlines Logo
6:55 pm - 2:00 pm
DSM
-
MVY
18h 05m
2 stops
Multiple Airlines Logo
12:15 pm - 11:02 pm
MVY
-
DSM
11h 47m
2 stops
$1,168Multiple Airlines
Fri, Oct 23 - Tue, Oct 27
Multiple Airlines Logo
6:55 pm - 2:00 pm
DSM
-
MVY
18h 05m
2 stops
Multiple Airlines Logo
8:59 am - 11:02 pm
MVY
-
DSM
15h 03m
3 stops
$1,173Multiple Airlines
Fri, Oct 23 - Tue, Oct 27

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American Airlines flights from Des Moines to Cape Cod and the Islands

Our best American Airlines deals on Des Moines to Cape Cod and the Islands flight tickets
American Airlines
Aug 6
DSM5:40 amDes Moines
5h 20m
1 stop
MVY12:00 pmWest Tisbury Martha's Vineyard
Aug 13
MVY5:25 pmWest Tisbury Martha's Vineyard
7h 19m
1 stop
DSM11:44 pmDes Moines
$484
American Airlines
Aug 6
DSM5:40 amDes Moines
7h 50m
1 stop
MVY2:30 pmWest Tisbury Martha's Vineyard
Aug 13
MVY12:30 pmWest Tisbury Martha's Vineyard
8h 55m
2 stops
DSM8:25 pmDes Moines
$586
American Airlines
Aug 6
DSM7:49 pmDes Moines
15h 11m
2 stops
MVY12:00 pmWest Tisbury Martha's Vineyard
Aug 13
MVY12:30 pmWest Tisbury Martha's Vineyard
8h 55m
2 stops
DSM8:25 pmDes Moines
$696

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Cape Cod and the Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Des Moines to Cape Cod and the Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Thu 8/6

5:40 am-12:00 pm

1 stop5h 20m

West Tisbury Martha's Vineyard

Thu 8/13

5:25 pm-11:44 pm

1 stop7h 19m

$484

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Thu 8/6

5:40 am-2:30 pm

1 stop7h 50m

West Tisbury Martha's Vineyard

Thu 8/13

12:30 pm-8:25 pm

2 stops8h 55m

$586

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Thu 8/6

7:49 pm-12:00 pm

2 stops15h 11m

West Tisbury Martha's Vineyard

Thu 8/13

12:30 pm-8:25 pm

2 stops8h 55m

$696

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Fri 10/23

6:55 pm-2:00 pm

2 stops18h 05m

West Tisbury Martha's Vineyard

Tue 10/27

12:15 pm-11:02 pm

2 stops11h 47m

$1,168

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Fri 10/23

6:55 pm-2:00 pm

2 stops18h 05m

West Tisbury Martha's Vineyard

Tue 10/27

8:59 am-11:02 pm

3 stops15h 03m

$1,173
Cheapest one-way

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Mon 7/27

7:15 am-2:59 pm

1 stop6h 44m

$484
Quickest one-way

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Mon 6/29

7:33 am-3:01 pm

1 stop6h 28m

$540

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Mon 6/29

6:08 am-3:01 pm

2 stops7h 53m

$546

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Wed 7/1

7:33 am-3:01 pm

1 stop6h 28m

$604

Des MoinesWest Tisbury

DSM - MVY

DSMMVY

Des Moines

Mon 7/27

5:41 am-2:59 pm

2 stops8h 18m

$610

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Cape Cod and the Islands from

How to get the cheapest flight ticket from Des Moines to Cape Cod and the Islands

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Cape Cod and the Islands?

Our data shows that Saturday is the least expensive day to fly to Cape Cod and the Islands. Tickets to fly out on this day can be as low as $132. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $209. These prices are subject to change though, so be sure to set up a Price Alert for flights to Cape Cod and the Islands.

How far in advance should I book a flight from Des Moines to Cape Cod and the Islands?

You are more likely to see cheaper flights to Cape Cod and the Islands from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Cape Cod and the Islands for around $313 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cape Cod and the Islands from Des Moines for as low as $184 on momondo.

Can stopping save me money on Des Moines to Cape Cod and the Islands flights?

No. A direct flight is the cheapest option for a flight between Des Moines to Cape Cod and the Islands.

Cheap Des Moines to Cape Cod and the Islands flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Cape Cod and the Islands

Fastest flight time

6h 28m

Direct flights

None
The fastest flight from Des Moines to Cape Cod and the Islands takes 6h 28m
There are no direct flights from Des Moines to Cape Cod and the Islands. There are no popular flight routes from Des Moines to Cape Cod and the Islands.

Frequently asked questions about flying from Des Moines to Cape Cod and the Islands

  • When did momondo last update prices for flights from Des Moines Airport to Cape Cod and the Islands?

    Prices for flights from Des Moines Airport to Cape Cod and the Islands were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Cape Cod and the Islands?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Cape Cod and the Islands.

  • What documentation or ID do you need to fly to Cape Cod and the Islands?

    The travel and health documents required for your trip to Cape Cod and the Islands can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Cape Cod and the Islands. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Des Moines to Cape Cod and the Islands?

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Cape Cod and the Islands?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Cape Cod and the Islands for you.

Can I find flights from Des Moines to Cape Cod and the Islands with flexible booking policies on momondo?

Flights from Des Moines to Cape Cod and the Islands with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Cape Cod and the Islands?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Cape Cod and the Islands from Des Moines.

I’m not ready to book a flight from Des Moines to Cape Cod and the Islands right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Cape Cod and the Islands from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Sat 7/25
Sat 8/1

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Popular cities in Cape Cod and the Islands

Popular flights according to clicks in the last 7 days on momondo