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Cheap flights from Denver to Knoxville from $68

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Knoxville departing on 2/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Denver to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
1:23 pm - 6:06 pm
DEN
-
TYS
2h 43mnonstop
Frontier Logo
8:13 pm - 9:44 pm
TYS
-
DEN
3h 31mnonstop
$132Frontier
Fri, Feb 27 - Mon, Mar 2
Frontier Logo
10:45 am - 3:30 pm
DEN
-
TYS
2h 45mnonstop
Frontier Logo
8:12 pm - 9:43 pm
TYS
-
DEN
3h 31mnonstop
$146Frontier
Fri, Feb 6 - Fri, Feb 13
Frontier Logo
10:45 am - 3:30 pm
DEN
-
TYS
2h 45mnonstop
Frontier Logo
8:12 pm - 9:43 pm
TYS
-
DEN
3h 31mnonstop
$148Frontier
Fri, Feb 6 - Fri, Feb 13
Frontier Logo
2:46 pm - 7:27 pm
DEN
-
TYS
2h 41mnonstop
Frontier Logo
8:13 pm - 9:44 pm
TYS
-
DEN
3h 31mnonstop
$157Frontier
Fri, Feb 13 - Mon, Feb 16
Frontier Logo
2:46 pm - 7:27 pm
DEN
-
TYS
2h 41mnonstop
Frontier Logo
8:13 pm - 9:44 pm
TYS
-
DEN
3h 31mnonstop
$158Frontier
Fri, Feb 13 - Mon, Feb 16
Multiple Airlines Logo
11:37 am - 10:10 pm
DEN
-
TYS
8h 33m
1 stop
Multiple Airlines Logo
5:56 pm - 10:22 am
TYS
-
DEN
18h 26m
1 stop
$162Multiple Airlines
Thu, Feb 19 - Sun, Feb 22
Allegiant Air Logo
9:11 am - 1:59 pm
DEN
-
TYS
2h 48mnonstop
Allegiant Air Logo
7:00 am - 8:21 am
TYS
-
DEN
3h 21mnonstop
$177Allegiant Air
Thu, May 21 - Sun, May 24
Multiple Airlines Logo
10:45 am - 3:30 pm
DEN
-
TYS
2h 45mnonstop
Multiple Airlines Logo
7:26 pm - 12:19 pm
TYS
-
DEN
42h 53m
2 stops
$202Multiple Airlines
Fri, Jan 30 - Sun, Feb 1
Multiple Airlines Logo
1:23 pm - 6:06 pm
DEN
-
TYS
2h 43mnonstop
Multiple Airlines Logo
9:36 pm - 9:41 pm
TYS
-
DEN
26h 05m
2 stops
$204Multiple Airlines
Fri, Feb 27 - Mon, Mar 2
Multiple Airlines Logo
2:46 pm - 7:27 pm
DEN
-
TYS
2h 41mnonstop
Multiple Airlines Logo
6:11 pm - 7:02 am
TYS
-
DEN
38h 51m
2 stops
$212Multiple Airlines
Fri, Feb 13 - Sun, Feb 15

Southwest flights from Denver to Knoxville

Our best Southwest deals on Denver to Knoxville flight tickets
Southwest
Mar 18
DEN12:25 pmDenver Intl
5h 40m
2 stops
TYS8:05 pmKnoxville McGhee Tyson
Apr 2
TYS3:45 pmKnoxville McGhee Tyson
8h 05m
1 stop
DEN9:50 pmDenver Intl
$254
Southwest
Apr 3
DEN1:25 pmDenver Intl
5h 50m
2 stops
TYS9:15 pmKnoxville McGhee Tyson
Apr 5
TYS6:35 amKnoxville McGhee Tyson
8h 15m
2 stops
DEN12:50 pmDenver Intl
$260
Southwest
Mar 6
DEN10:30 amDenver Intl
9h 40m
2 stops
TYS10:10 pmKnoxville McGhee Tyson
Mar 11
TYS6:20 pmKnoxville McGhee Tyson
7h 15m
1 stop
DEN11:35 pmDenver Intl
$279

Delta flights from Denver to Knoxville

Our best Delta deals on Denver to Knoxville flight tickets
Delta
Jan 30
DEN11:25 amDenver Intl
6h 57m
1 stop
TYS8:22 pmKnoxville McGhee Tyson
Feb 5
TYS6:41 pmKnoxville McGhee Tyson
7h 47m
1 stop
DEN12:28 amDenver Intl
$274
Delta
Jan 22
DEN2:42 pmDenver Intl
7h 03m
1 stop
TYS11:45 pmKnoxville McGhee Tyson
Jan 28
TYS5:00 pmKnoxville McGhee Tyson
7h 50m
1 stop
DEN10:50 pmDenver Intl
$399
Delta
Jan 21
DEN10:50 amDenver Intl
5h 06m
1 stop
TYS5:56 pmKnoxville McGhee Tyson
Jan 28
TYS5:00 pmKnoxville McGhee Tyson
7h 50m
1 stop
DEN10:50 pmDenver Intl
$454

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/27

1:23 pm-6:06 pm

Nonstop2h 43m

Knoxville McGhee Tyson

Mon 3/2

8:13 pm-9:44 pm

Nonstop3h 31m

$132

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/6

10:45 am-3:30 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Fri 2/13

8:12 pm-9:43 pm

Nonstop3h 31m

$146

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/6

10:45 am-3:30 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Fri 2/13

8:12 pm-9:43 pm

Nonstop3h 31m

$148

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/13

2:46 pm-7:27 pm

Nonstop2h 41m

Knoxville McGhee Tyson

Mon 2/16

8:13 pm-9:44 pm

Nonstop3h 31m

$157

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/13

2:46 pm-7:27 pm

Nonstop2h 41m

Knoxville McGhee Tyson

Mon 2/16

8:13 pm-9:44 pm

Nonstop3h 31m

$158

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 2/19

11:37 am-10:10 pm

1 stop8h 33m

Knoxville McGhee Tyson

Sun 2/22

5:56 pm-10:22 am

1 stop18h 26m

$162

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 5/21

9:11 am-1:59 pm

Nonstop2h 48m

Knoxville McGhee Tyson

Sun 5/24

7:00 am-8:21 am

Nonstop3h 21m

$177

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 1/30

10:45 am-3:30 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Sun 2/1

7:26 pm-12:19 pm

2 stops42h 53m

$202

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/27

1:23 pm-6:06 pm

Nonstop2h 43m

Knoxville McGhee Tyson

Mon 3/2

9:36 pm-9:41 pm

2 stops26h 05m

$204

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/13

2:46 pm-7:27 pm

Nonstop2h 41m

Knoxville McGhee Tyson

Sun 2/15

6:11 pm-7:02 am

2 stops38h 51m

$212

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Denver to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Denver, with most prices found around $174. If you aren’t able to travel during the month of August, then book flights to Knoxville from Denver during November instead. Flights to Knoxville in November, while not as cheap as those in August, still average around $199.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Denver to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $170. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Knoxville for around $376.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Denver to Knoxville when you can find flight prices for as low as $171. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $243.

What is the cheapest Denver Intl to Knoxville McGhee Tyson flight route?

Fly from Denver Intl to Knoxville McGhee Tyson for the best Denver Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $252 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Denver for as low as $192 on momondo.

What cabin class options are available on Denver Intl to Knoxville McGhee Tyson flights?

There are 2 cabin classes available to choose from on Denver Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Denver to Knoxville flight prices changed over time?

As of January 2026, prices for Denver to Knoxville flights are approximately 53% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Knoxville (DEN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Knoxville

Best Price Found

$134

Fastest flight time

2h 41m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Denver in the past 72 hours is $134. The best round-trip flight deal from Denver to Knoxville found on momondo in the last 72 hours is $264.
The fastest flight from Denver to Knoxville takes 2h 41m
Direct flights go from Denver to Knoxville every day.
There is 1 airport in Knoxville. From Denver there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • How far is Denver Intl to Knoxville McGhee Tyson by plane?

    Denver Intl and Knoxville McGhee Tyson are 1174.7 mi apart from one another. Flights usually cover this in 2h 41m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Denver to Knoxville?

  • What is the most popular airline from Denver to Knoxville?

Best airlines flying from Denver to Knoxville

Compare and see reviews for airlines that fly from Denver to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $58Free CancellationRating
7.2
702 reviews
Search Allegiant Air flights
FrontierPriceFrom $66Free CancellationRating
5.7
3,057 reviews
Search Frontier flights
DeltaPriceFrom $128Free CancellationRating
7.9
8,050 reviews
Search Delta flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
11,135 reviews
Search American Airlines flights
United AirlinesPriceFrom $229Free CancellationRating
7.4
9,163 reviews
Search United Airlines flights
SouthwestPriceFrom $248Free CancellationRating
8.0
4,258 reviews
Search Southwest flights

  • United Airlines Flights From Denver to Knoxville

    United Airlines operates around 14 flights from Denver to Knoxville every week. The average price of these flights found in the last 72 hours has been $395, but momondo users have found United Airlines deals from Denver to Knoxville from as low as $229 round-trip. United Airlines has been scored 7.4/10 in 9,163 reviews.

  • Frontier Flights From Denver to Knoxville

    Frontier is also a popular choice for this route. Frontier flight deals for Denver to Knoxville start from as low as $66 round-trip, depending on your selected dates, with average Frontier deals seen on momondo around $186. Frontier operates 2 flights to Knoxville from Denver in an average week. Users have rated it 5.7/10 across 3,057 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Murphy
Maryville
Alcoa
Crossville
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Denver to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Denver to Knoxville.

I’m not ready to book a flight from Denver to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Denver are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Knoxville trip

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