Cheap flights from Denver to Knoxville from $43
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Knoxville departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 10/29
8:26 am-1:11 pm
Nonstop2h 45m
Knoxville McGhee Tyson
Thu 11/5
6:30 am-7:40 am
Nonstop3h 10m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 11/19
10:15 am-2:52 pm
Nonstop2h 37m
Knoxville McGhee Tyson
Sun 11/22
6:20 am-7:45 am
Nonstop3h 25m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 11/12
8:30 am-1:19 pm
Nonstop2h 49m
Knoxville McGhee Tyson
Sun 11/15
7:30 am-8:13 am
2 stops26h 43m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 11/12
8:30 am-1:19 pm
Nonstop2h 49m
Knoxville McGhee Tyson
Mon 11/16
2:21 pm-8:22 am
2 stops44h 01m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 10/29
11:18 am-4:04 pm
Nonstop2h 46m
Knoxville McGhee Tyson
Mon 11/2
9:00 am-10:28 am
Nonstop3h 28m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Wed 10/28
10:15 am-3:01 pm
Nonstop2h 46m
Knoxville McGhee Tyson
Tue 11/10
9:00 am-10:28 am
Nonstop3h 28m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 1/28
11:10 am-3:45 pm
Nonstop2h 35m
Knoxville McGhee Tyson
Mon 2/1
5:50 pm-7:25 pm
Nonstop3h 35m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 1/21
11:10 am-3:45 pm
Nonstop2h 35m
Knoxville McGhee Tyson
Sat 1/23
4:20 pm-5:55 pm
Nonstop3h 35m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 12/24
3:14 pm-11:41 pm
1 stop6h 27m
Knoxville McGhee Tyson
Thu 12/31
3:06 pm-8:47 pm
1 stop7h 41m
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Mon 11/16
3:41 pm-10:48 pm
1 stop5h 07m
Knoxville McGhee Tyson
Sat 11/21
6:05 pm-11:40 pm
1 stop7h 35m
See travel insights to Knoxville from
How to get the cheapest flight ticket from Denver to Knoxville
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between Denver and Knoxville?
Prices are currently low for flights on this route.
Typical prices usually range from $218 to $451.The lowest price recently found on this route was $166.
What is the cheapest month to fly to Knoxville?
The month of August is, on average, the cheapest month to fly to Knoxville from Denver, with most prices found around $189. If you aren’t able to travel during the month of August, then book flights to Knoxville from Denver during December instead. Flights to Knoxville in December, while not as cheap as those in August, still average around $248.
What is the cheapest day to depart on your flight to Knoxville?
The cheapest day to depart from Denver to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $227. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Knoxville for around $383.
What is the cheapest time of day to depart on your flight to Knoxville?
At noon is the cheapest time of day to fly from Denver to Knoxville when you can find flight prices for as low as $263. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $379.
What is the cheapest Denver Intl to Knoxville McGhee Tyson flight route?
Fly from Denver Intl to Knoxville McGhee Tyson for the best Denver Intl - Knoxville McGhee Tyson flight prices
How far in advance should I book a flight from Denver to Knoxville?
You are more likely to see cheaper flights to Knoxville from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $322 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Denver for as low as $170 on momondo.
What cabin class options are available on Denver to Knoxville flights?
There are 4 cabin classes available to choose from on Denver to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
What is the cheapest airline that flies from Denver Intl to Knoxville McGhee Tyson?
Southwest, Delta, and United Airlines are the most popular carriers operating from Denver Intl to Knoxville McGhee Tyson
What airlines fly to Knoxville?
United Airlines, Allegiant Air and American Airlines are the top three most popular airlines that fly to Knoxville from Denver according to our data. United Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 6 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.
How many flights depart from Denver to Knoxville on average per day?
The number of flights available between Denver and Knoxville is 2 per day as of October 2026. The most frequent departure time is 5:00PM, with 58% of daily flights leaving at noon.
How many flights depart from Denver to Knoxville on average per week?
As of October 2026, there are 20 flights per week flying from Denver to Knoxville. The most common day of the week flights depart is Sun, with 20% of flights taking off on this day.
When to book flights from Denver to Knoxville
Cheap Denver to Knoxville (DEN to TYS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Denver to Knoxville
Frequently asked questions about flying from Denver to Knoxville
How far is Denver Intl to Knoxville McGhee Tyson by plane?
Denver Intl and Knoxville McGhee Tyson are 1174.7 mi apart from one another. Flights usually cover this in 2h 30m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport are updated daily.
How many operators does momondo search for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?
As of October 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Denver Intl Airport to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Denver to Knoxville?
momondo data reveals that the most frequently booked plane model on the route from Denver to Knoxville is Airbus A320-100/200, representing 64.59% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 7.39%, Airbus A319 at 7.00%, and Boeing 737-800 Passenger/BBJ2 (winglets) at 5.45%.
What is the most popular airline from Denver to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Denver to Knoxville is United Airlines (47% of total bookings). The next most popular airlines are Allegiant Air (22%), Frontier (20%), and Southwest (7%).
Best airlines flying from Denver to Knoxville
Compare and see reviews for airlines that fly from Denver to Knoxville with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $67 | Free Cancellation | Rating 7.3 678 reviews | |||
| PriceFrom $84 | Free Cancellation | Rating 5.5 2,550 reviews | |||
| PriceFrom $124 | Free Cancellation | Rating 7.8 8,630 reviews | |||
| PriceFrom $219 | Free Cancellation | Rating 7.0 12,132 reviews | |||
| PriceFrom $229 | Free Cancellation | Rating 7.4 10,287 reviews | |||
| PriceFrom $249 | Free Cancellation | Rating 7.9 4,213 reviews |
Southwest Flights From Denver to Knoxville
Southwest operates around 5 flights from Denver to Knoxville every week. The average price of these flights found in the last 72 hours has been $437, but momondo users have found Southwest deals from Denver to Knoxville from as low as $249 round-trip. Southwest has been scored 7.9/10 in 4,213 reviews.
United Airlines Flights From Denver to Knoxville
United Airlines is also a popular choice for this route. United Airlines flight deals for Denver to Knoxville start from as low as $229 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $424. United Airlines operates 14 flights to Knoxville from Denver in an average week. Users have rated it 7.4/10 across 10,287 reviews.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Denver to Knoxville?
momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Knoxville. momondo saves you time and could save you money on your trip.
Can I find flights from Denver to Knoxville with flexible booking policies on momondo?
momondo does allow users to show only those flights to Knoxville from Denver which offer a flexible booking policy as well as other useful filters and features.
How can momondo help me find flights from Denver to Knoxville?
momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Denver to Knoxville.
I’m not ready to book a flight from Denver to Knoxville right now. Can momondo alert me if prices change?
Price alerts on flights to Knoxville from Denver are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.