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Cheap flights from Denver to Knoxville from $49

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Knoxville departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Denver to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
8:33 am - 1:11 pmDEN-TYS
2h 38mnonstop
Allegiant Air Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$92Allegiant Air
Find Deal
Sun, Dec 7 - Thu, Dec 11
Allegiant Air Logo
8:33 am - 1:11 pmDEN-TYS
2h 38mnonstop
Allegiant Air Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$96Allegiant Air
Find Deal
Thu, Dec 11 - Sun, Dec 14
Allegiant Air Logo
8:33 am - 1:11 pmDEN-TYS
2h 38mnonstop
Allegiant Air Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$108Allegiant Air
Find Deal
Thu, Dec 11 - Sun, Dec 14
Allegiant Air Logo
8:33 am - 1:11 pmDEN-TYS
2h 38mnonstop
Allegiant Air Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$109Allegiant Air
Find Deal
Thu, Dec 4 - Sun, Dec 7
Frontier Logo
11:12 am - 3:57 pmDEN-TYS
2h 45mnonstop
Frontier Logo
4:52 pm - 6:23 pmTYS-DEN
3h 31mnonstop
$112Frontier
Find Deal
Mon, Dec 8 - Thu, Dec 11
Multiple Airlines Logo
10:00 am - 7:14 pmDEN-TYS
7h 14m1 stop
Multiple Airlines Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$152Multiple Airlines
Find Deal
Fri, Dec 12 - Sun, Dec 14
Multiple Airlines Logo
9:00 pm - 7:14 pmDEN-TYS
20h 14m1 stop
Multiple Airlines Logo
4:52 pm - 6:23 pmTYS-DEN
3h 31mnonstop
$155Multiple Airlines
Find Deal
Thu, Dec 11 - Sun, Dec 14
Frontier Logo
10:43 am - 3:28 pmDEN-TYS
2h 45mnonstop
Frontier Logo
4:23 pm - 5:54 pmTYS-DEN
3h 31mnonstop
$162Frontier
Find Deal
Thu, Jan 8 - Sun, Jan 11
Multiple Airlines Logo
12:59 am - 9:37 pmDEN-TYS
18h 38m2 stops
Multiple Airlines Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$164Multiple Airlines
Find Deal
Wed, Dec 10 - Sun, Dec 14
Multiple Airlines Logo
10:00 am - 7:14 pmDEN-TYS
7h 14m1 stop
Multiple Airlines Logo
4:52 pm - 6:23 pmTYS-DEN
3h 31mnonstop
$167Multiple Airlines
Find Deal
Fri, Dec 12 - Mon, Dec 15

Allegiant Air flights from Denver to Knoxville

Our best Allegiant Air deals on Denver to Knoxville flight tickets
Allegiant Air
Dec 7
DEN8:33 amDenver Intl
2h 38m
TYS1:11 pmKnoxville McGhee Tyson
Dec 11
TYS6:30 amKnoxville McGhee Tyson
3h 13m
DEN7:43 amDenver Intl
$92
Find similar
Allegiant Air
Dec 11
DEN8:33 amDenver Intl
2h 38m
TYS1:11 pmKnoxville McGhee Tyson
Dec 14
TYS6:30 amKnoxville McGhee Tyson
3h 13m
DEN7:43 amDenver Intl
$96
Find similar
Allegiant Air
Dec 11
DEN8:33 amDenver Intl
2h 38m
TYS1:11 pmKnoxville McGhee Tyson
Dec 14
TYS6:30 amKnoxville McGhee Tyson
3h 13m
DEN7:43 amDenver Intl
$108
Find similar

United Airlines flights from Denver to Knoxville

Our best United Airlines deals on Denver to Knoxville flight tickets
United Airlines
May 6
DEN9:47 amDenver Intl
2h 54m
TYS2:41 pmKnoxville McGhee Tyson
May 9
TYS4:25 pmKnoxville McGhee Tyson
3h 25m
DEN5:50 pmDenver Intl
$229
Find similar
United Airlines
May 6
DEN9:47 amDenver Intl
2h 54m
TYS2:41 pmKnoxville McGhee Tyson
May 9
TYS5:50 amKnoxville McGhee Tyson
8h 28m
1 stop
DEN12:18 pmDenver Intl
$239
Find similar
United Airlines
Dec 12
DEN11:59 pmDenver Intl
8h 49m
1 stop
TYS10:48 amKnoxville McGhee Tyson
Dec 15
TYS7:25 pmKnoxville McGhee Tyson
6h 50m
1 stop
DEN12:15 amDenver Intl
$249
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 12/7

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Thu 12/11

6:30 am-7:43 am

Nonstop3h 13m

$92

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/11

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Sun 12/14

6:30 am-7:43 am

Nonstop3h 13m

$96

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/11

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Sun 12/14

6:30 am-7:43 am

Nonstop3h 13m

$108

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/4

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Sun 12/7

6:30 am-7:43 am

Nonstop3h 13m

$109

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 12/8

11:12 am-3:57 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Thu 12/11

4:52 pm-6:23 pm

Nonstop3h 31m

$112

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 12/12

10:00 am-7:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

Sun 12/14

6:30 am-7:43 am

Nonstop3h 13m

$152

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/11

9:00 pm-7:14 pm

1 stop20h 14m

Knoxville McGhee Tyson

Sun 12/14

4:52 pm-6:23 pm

Nonstop3h 31m

$155

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 1/8

10:43 am-3:28 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Sun 1/11

4:23 pm-5:54 pm

Nonstop3h 31m

$162

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 12/10

12:59 am-9:37 pm

2 stops18h 38m

Knoxville McGhee Tyson

Sun 12/14

6:30 am-7:43 am

Nonstop3h 13m

$164

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 12/12

10:00 am-7:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

Mon 12/15

4:52 pm-6:23 pm

Nonstop3h 31m

$167

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Knoxville from

How to get the cheapest flight ticket from Denver to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Denver, with most prices found around $179. If you aren’t able to travel during the month of August, then book flights to Knoxville from Denver during April instead. Flights to Knoxville in April, while not as cheap as those in August, still average around $181.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Denver to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $169. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Knoxville for around $377.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Denver to Knoxville when you can find flight prices for as low as $164. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $244.

What is the cheapest Denver Intl to Knoxville McGhee Tyson flight route?

Fly from Denver Intl to Knoxville McGhee Tyson for the best Denver Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $258 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Denver for as low as $197 on momondo.

What cabin class options are available on Denver Intl to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Denver Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Denver to Knoxville flight prices changed over time?

As of November 2025, prices for Denver to Knoxville flights are approximately 15% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Knoxville (DEN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Knoxville

Best Price Found

$124

Fastest flight time

2h 38m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Denver in the past 72 hours is $124. The best round-trip flight deal from Denver to Knoxville found on momondo in the last 72 hours is $187.
The fastest flight from Denver to Knoxville takes 2h 38m
Direct flights go from Denver to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Denver Intl to Knoxville McGhee Tyson by plane?

    Denver Intl and Knoxville McGhee Tyson are 1174.7 mi apart from one another. Flights usually cover this in 2h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Denver to Knoxville?

  • What is the most popular airline from Denver to Knoxville?

Best airlines flying from Denver to Knoxville

Compare and see reviews for airlines that fly from Denver to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $64Free CancellationRating
7.2
700 reviews
Search Allegiant Air flights
FrontierPriceFrom $81Free CancellationRating
5.8
3,106 reviews
Search Frontier flights
DeltaPriceFrom $133Free CancellationRating
7.9
8,002 reviews
Search Delta flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
9,029 reviews
Search United Airlines flights

  • United Airlines Flights From Denver to Knoxville

    United Airlines operates around 13 flights from Denver to Knoxville every week. The average price of these flights found in the last 72 hours has been $433, but momondo users have found United Airlines deals from Denver to Knoxville from as low as $233 round-trip. United Airlines has been scored 7.4/10 in 9,029 reviews.

  • Allegiant Air Flights From Denver to Knoxville

    Allegiant Air is also a popular choice for this route. Allegiant Air flight deals for Denver to Knoxville start from as low as $64 round-trip, depending on your selected dates, with average Allegiant Air deals seen on momondo around $132. Allegiant Air operates 1 flight to Knoxville from Denver in an average week. Users have rated it 7.2/10 across 700 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Denver to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Denver to Knoxville.

I’m not ready to book a flight from Denver to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Denver are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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