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Cheap flights from Denver to Knoxville from $52

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Knoxville departing on 8/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Denver to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
9:11 am - 2:01 pm
DEN
-
TYS
2h 50mnonstop
Allegiant Air Logo
7:00 am - 8:21 am
TYS
-
DEN
3h 21mnonstop
$143Allegiant Air
Thu, Aug 6 - Sun, Aug 9
Multiple Airlines Logo
8:52 pm - 12:17 pm
DEN
-
TYS
13h 25m
1 stop
Multiple Airlines Logo
7:00 am - 8:21 am
TYS
-
DEN
3h 21mnonstop
$144Multiple Airlines
Thu, Aug 6 - Thu, Aug 13
Allegiant Air Logo
9:11 am - 2:01 pm
DEN
-
TYS
2h 50mnonstop
Allegiant Air Logo
7:00 am - 8:21 am
TYS
-
DEN
3h 21mnonstop
$146Allegiant Air
Thu, Aug 6 - Thu, Aug 13
Multiple Airlines Logo
9:11 am - 2:01 pm
DEN
-
TYS
2h 50mnonstop
Multiple Airlines Logo
8:30 am - 11:32 am
TYS
-
DEN
29h 02m
1 stop
$148Multiple Airlines
Thu, Aug 13 - Fri, Aug 21
Allegiant Air Logo
9:11 am - 2:01 pm
DEN
-
TYS
2h 50mnonstop
Allegiant Air Logo
7:00 am - 8:21 am
TYS
-
DEN
3h 21mnonstop
$152Allegiant Air
Thu, Aug 6 - Thu, Aug 13
Allegiant Air Logo
8:55 am - 1:44 pm
DEN
-
TYS
2h 49mnonstop
Allegiant Air Logo
6:30 am - 7:36 am
TYS
-
DEN
3h 06mnonstop
$153Allegiant Air
Sun, Sep 27 - Thu, Oct 1
Multiple Airlines Logo
2:46 pm - 7:37 pm
DEN
-
TYS
2h 51mnonstop
Multiple Airlines Logo
7:00 am - 8:10 am
TYS
-
DEN
3h 10mnonstop
$155Multiple Airlines
Wed, Aug 19 - Sun, Aug 23
Multiple Airlines Logo
9:11 am - 2:01 pm
DEN
-
TYS
2h 50mnonstop
Multiple Airlines Logo
8:32 pm - 9:55 pm
TYS
-
DEN
3h 23mnonstop
$156Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
8:52 pm - 12:17 pm
DEN
-
TYS
13h 25m
1 stop
Multiple Airlines Logo
7:00 am - 8:21 am
TYS
-
DEN
3h 21mnonstop
$158Multiple Airlines
Thu, Aug 13 - Sun, Aug 16
Multiple Airlines Logo
8:55 am - 1:44 pm
DEN
-
TYS
2h 49mnonstop
Multiple Airlines Logo
8:00 am - 8:10 am
TYS
-
DEN
26h 10m
1 stop
$159Multiple Airlines
Thu, Sep 10 - Mon, Sep 14

Allegiant Air flights from Denver to Knoxville

Our best Allegiant Air deals on Denver to Knoxville flight tickets
Allegiant Air
Aug 6
DEN9:11 amDenver Intl
2h 50m
TYS2:01 pmKnoxville McGhee Tyson
Aug 9
TYS7:00 amKnoxville McGhee Tyson
3h 21m
DEN8:21 amDenver Intl
$143
Allegiant Air
Aug 6
DEN9:11 amDenver Intl
2h 50m
TYS2:01 pmKnoxville McGhee Tyson
Aug 13
TYS7:00 amKnoxville McGhee Tyson
3h 21m
DEN8:21 amDenver Intl
$146
Allegiant Air
Aug 6
DEN9:11 amDenver Intl
2h 50m
TYS2:01 pmKnoxville McGhee Tyson
Aug 13
TYS7:00 amKnoxville McGhee Tyson
3h 21m
DEN8:21 amDenver Intl
$152

Frontier flights from Denver to Knoxville

Our best Frontier deals on Denver to Knoxville flight tickets
Frontier
Aug 5
DEN2:46 pmDenver Intl
2h 50m
TYS7:36 pmKnoxville McGhee Tyson
Aug 12
TYS8:32 pmKnoxville McGhee Tyson
3h 23m
DEN9:55 pmDenver Intl
$163
Frontier
Jun 10
DEN2:46 pmDenver Intl
2h 51m
TYS7:37 pmKnoxville McGhee Tyson
Jun 15
TYS8:32 pmKnoxville McGhee Tyson
3h 40m
DEN10:12 pmDenver Intl
$168
Frontier
Aug 14
DEN2:46 pmDenver Intl
2h 50m
TYS7:36 pmKnoxville McGhee Tyson
Aug 19
TYS8:32 pmKnoxville McGhee Tyson
3h 40m
DEN10:12 pmDenver Intl
$193

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/6

9:11 am-2:01 pm

Nonstop2h 50m

Knoxville McGhee Tyson

Sun 8/9

7:00 am-8:21 am

Nonstop3h 21m

$143

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/6

8:52 pm-12:17 pm

1 stop13h 25m

Knoxville McGhee Tyson

Thu 8/13

7:00 am-8:21 am

Nonstop3h 21m

$144

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/6

9:11 am-2:01 pm

Nonstop2h 50m

Knoxville McGhee Tyson

Thu 8/13

7:00 am-8:21 am

Nonstop3h 21m

$146

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/13

9:11 am-2:01 pm

Nonstop2h 50m

Knoxville McGhee Tyson

Fri 8/21

8:30 am-11:32 am

1 stop29h 02m

$148

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/6

9:11 am-2:01 pm

Nonstop2h 50m

Knoxville McGhee Tyson

Thu 8/13

7:00 am-8:21 am

Nonstop3h 21m

$152
Quickest round-trip

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 9/27

8:55 am-1:44 pm

Nonstop2h 49m

Knoxville McGhee Tyson

Thu 10/1

6:30 am-7:36 am

Nonstop3h 06m

$153

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 8/19

2:46 pm-7:37 pm

Nonstop2h 51m

Knoxville McGhee Tyson

Sun 8/23

7:00 am-8:10 am

Nonstop3h 10m

$155

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/13

9:11 am-2:01 pm

Nonstop2h 50m

Knoxville McGhee Tyson

Mon 8/17

8:32 pm-9:55 pm

Nonstop3h 23m

$156

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/13

8:52 pm-12:17 pm

1 stop13h 25m

Knoxville McGhee Tyson

Sun 8/16

7:00 am-8:21 am

Nonstop3h 21m

$158

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/10

8:55 am-1:44 pm

Nonstop2h 49m

Knoxville McGhee Tyson

Mon 9/14

8:00 am-8:10 am

1 stop26h 10m

$159

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Denver to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Denver, with most prices found around $184. If you aren’t able to travel during the month of August, then book flights to Knoxville from Denver during November instead. Flights to Knoxville in November, while not as cheap as those in August, still average around $199.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Denver to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $195. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Knoxville for around $384.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Denver to Knoxville when you can find flight prices for as low as $202. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $315.

What is the cheapest Denver Intl to Knoxville McGhee Tyson flight route?

Fly from Denver Intl to Knoxville McGhee Tyson for the best Denver Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight from Denver to Knoxville?

You are more likely to see cheaper flights to Knoxville from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $292 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Denver for as low as $154 on momondo.

What cabin class options are available on Denver to Knoxville flights?

There are 2 cabin classes available to choose from on Denver to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Denver to Knoxville flight prices changed over time?

As of May 2026, prices for Denver to Knoxville flights are approximately 36% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Knoxville (DEN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Knoxville

Best Price Found

$114

Fastest flight time

2h 40m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Denver in the past 72 hours is $114. The best round-trip flight deal from Denver to Knoxville found on momondo in the last 72 hours is $169.
The fastest flight from Denver to Knoxville takes 2h 40m
Direct flights go from Denver to Knoxville on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There is 1 airport in Knoxville. From Denver there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Denver to Knoxville

  • How far is Denver Intl to Knoxville McGhee Tyson by plane?

    Denver Intl and Knoxville McGhee Tyson are 1174.7 mi apart from one another. Flights usually cover this in 2h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Denver to Knoxville?

  • What is the most popular airline from Denver to Knoxville?

Best airlines flying from Denver to Knoxville

Compare and see reviews for airlines that fly from Denver to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $59Free CancellationRating
7.3
709 reviews
Search Allegiant Air flights
FrontierPriceFrom $81Free CancellationRating
5.6
2,945 reviews
Search Frontier flights
DeltaPriceFrom $124Free CancellationRating
7.9
8,452 reviews
Search Delta flights
American AirlinesPriceFrom $218Free CancellationRating
7.1
11,644 reviews
Search American Airlines flights
United AirlinesPriceFrom $229Free CancellationRating
7.4
9,744 reviews
Search United Airlines flights
SouthwestPriceFrom $248Free CancellationRating
7.9
4,284 reviews
Search Southwest flights

  • United Airlines Flights From Denver to Knoxville

    United Airlines operates around 6 flights from Denver to Knoxville every week. The average price of these flights found in the last 72 hours has been $403, but momondo users have found United Airlines deals from Denver to Knoxville from as low as $229 round-trip. United Airlines has been scored 7.4/10 in 9,744 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Denver to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Denver to Knoxville.

I’m not ready to book a flight from Denver to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Denver are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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