Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Denver to Knoxville from $54

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Knoxville departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Denver to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
8:54 am - 1:33 pmDEN-TYS
2h 39mnonstop
Allegiant Air Logo
7:00 am - 8:15 amTYS-DEN
3h 15mnonstop
$106Allegiant Air
Find Deal
Sun, Nov 2 - Sun, Nov 9
Allegiant Air Logo
8:33 am - 1:11 pmDEN-TYS
2h 38mnonstop
Allegiant Air Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$110Allegiant Air
Find Deal
Thu, Dec 11 - Sun, Dec 14
Allegiant Air Logo
8:54 am - 1:33 pmDEN-TYS
2h 39mnonstop
Allegiant Air Logo
7:00 am - 8:15 amTYS-DEN
3h 15mnonstop
$126Allegiant Air
Find Deal
Thu, Oct 30 - Thu, Nov 6
Allegiant Air Logo
9:05 am - 1:44 pmDEN-TYS
2h 39mnonstop
Allegiant Air Logo
6:30 am - 7:55 amTYS-DEN
3h 25mnonstop
$133Allegiant Air
Find Deal
Thu, Nov 6 - Sun, Nov 23
Multiple Airlines Logo
9:05 am - 1:44 pmDEN-TYS
2h 39mnonstop
Multiple Airlines Logo
7:17 pm - 8:34 pmTYS-DEN
3h 17mnonstop
$134Multiple Airlines
Find Deal
Thu, Nov 13 - Thu, Nov 13
Allegiant Air Logo
8:54 am - 1:33 pmDEN-TYS
2h 39mnonstop
Allegiant Air Logo
7:00 am - 8:15 amTYS-DEN
3h 15mnonstop
$136Allegiant Air
Find Deal
Thu, Oct 30 - Thu, Nov 6
Frontier Logo
2:43 pm - 7:32 pmDEN-TYS
2h 49mnonstop
Frontier Logo
8:17 pm - 9:39 pmTYS-DEN
3h 22mnonstop
$138Frontier
Find Deal
Sun, Oct 26 - Mon, Oct 27
Multiple Airlines Logo
9:00 pm - 11:11 pmDEN-TYS
24h 11m1 stop
Multiple Airlines Logo
6:30 am - 7:43 amTYS-DEN
3h 13mnonstop
$156Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Frontier Logo
11:06 am - 3:51 pmDEN-TYS
2h 45mnonstop
Frontier Logo
4:26 pm - 5:57 pmTYS-DEN
3h 31mnonstop
$196Frontier
Find Deal
Tue, Dec 23 - Thu, Dec 25
United Airlines Logo
11:15 am - 8:09 pmDEN-TYS
6h 54m1 stop
United Airlines Logo
4:55 pm - 6:20 pmTYS-DEN
3h 25mnonstop
$239United Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 21

Allegiant Air flights from Denver to Knoxville

Our best Allegiant Air deals on Denver to Knoxville flight tickets
Allegiant Air
Nov 2
DEN8:54 amDenver Intl
2h 39m
TYS1:33 pmKnoxville McGhee Tyson
Nov 9
TYS7:00 amKnoxville McGhee Tyson
3h 15m
DEN8:15 amDenver Intl
$106
Find similar
Allegiant Air
Dec 11
DEN8:33 amDenver Intl
2h 38m
TYS1:11 pmKnoxville McGhee Tyson
Dec 14
TYS6:30 amKnoxville McGhee Tyson
3h 13m
DEN7:43 amDenver Intl
$110
Find similar
Allegiant Air
Oct 30
DEN8:54 amDenver Intl
2h 39m
TYS1:33 pmKnoxville McGhee Tyson
Nov 6
TYS7:00 amKnoxville McGhee Tyson
3h 15m
DEN8:15 amDenver Intl
$126
Find similar

United Airlines flights from Denver to Knoxville

Our best United Airlines deals on Denver to Knoxville flight tickets
United Airlines
Nov 11
DEN11:15 amDenver Intl
6h 54m
1 stop
TYS8:09 pmKnoxville McGhee Tyson
Nov 21
TYS4:55 pmKnoxville McGhee Tyson
3h 25m
DEN6:20 pmDenver Intl
$239
Find similar
United Airlines
Nov 3
DEN5:30 pmDenver Intl
3h 00m
TYS10:30 pmKnoxville McGhee Tyson
Nov 14
TYS5:45 amKnoxville McGhee Tyson
6h 39m
1 stop
DEN10:24 amDenver Intl
$254
Find similar
United Airlines
Nov 4
DEN9:55 amDenver Intl
2h 48m
TYS2:43 pmKnoxville McGhee Tyson
Nov 8
TYS8:26 amKnoxville McGhee Tyson
8h 24m
1 stop
DEN2:50 pmDenver Intl
$269
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 11/2

8:54 am-1:33 pm

Nonstop2h 39m

Knoxville McGhee Tyson

Sun 11/9

7:00 am-8:15 am

Nonstop3h 15m

$106

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/11

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Sun 12/14

6:30 am-7:43 am

Nonstop3h 13m

$110

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 10/30

8:54 am-1:33 pm

Nonstop2h 39m

Knoxville McGhee Tyson

Thu 11/6

7:00 am-8:15 am

Nonstop3h 15m

$126

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 11/6

9:05 am-1:44 pm

Nonstop2h 39m

Knoxville McGhee Tyson

Sun 11/23

6:30 am-7:55 am

Nonstop3h 25m

$133

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 11/13

9:05 am-1:44 pm

Nonstop2h 39m

Knoxville McGhee Tyson

Thu 11/13

7:17 pm-8:34 pm

Nonstop3h 17m

$134

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 10/30

8:54 am-1:33 pm

Nonstop2h 39m

Knoxville McGhee Tyson

Thu 11/6

7:00 am-8:15 am

Nonstop3h 15m

$136

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 10/26

2:43 pm-7:32 pm

Nonstop2h 49m

Knoxville McGhee Tyson

Mon 10/27

8:17 pm-9:39 pm

Nonstop3h 22m

$138

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/4

9:00 pm-11:11 pm

1 stop24h 11m

Knoxville McGhee Tyson

Sun 12/7

6:30 am-7:43 am

Nonstop3h 13m

$156

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Tue 12/23

11:06 am-3:51 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Thu 12/25

4:26 pm-5:57 pm

Nonstop3h 31m

$196

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Tue 11/11

11:15 am-8:09 pm

1 stop6h 54m

Knoxville McGhee Tyson

Fri 11/21

4:55 pm-6:20 pm

Nonstop3h 25m

$239

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Denver to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Denver, with most prices found around $179. If you aren’t able to travel during the month of August, then book flights to Knoxville from Denver during April instead. Flights to Knoxville in April, while not as cheap as those in August, still average around $192.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Denver to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $171. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Knoxville for around $371.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Denver to Knoxville when you can find flight prices for as low as $153. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $246.

What is the cheapest Denver Intl to Knoxville McGhee Tyson flight route?

Fly from Denver Intl to Knoxville McGhee Tyson for the best Denver Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $259 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Denver for as low as $176 on momondo.

What cabin class options are available on Denver Intl to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Denver Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Denver to Knoxville flight prices changed over time?

As of October 2025, prices for Denver to Knoxville flights are approximately 45% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Knoxville (DEN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Knoxville

Best Price Found

$138

Fastest flight time

2h 38m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Denver in the past 72 hours is $138. The best round-trip flight deal from Denver to Knoxville found on momondo in the last 72 hours is $187.
The fastest flight from Denver to Knoxville takes 2h 38m
Direct flights go from Denver to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Denver Intl to Knoxville McGhee Tyson by plane?

    Denver Intl and Knoxville McGhee Tyson are 1174.7 mi apart from one another. Flights usually cover this in 2h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Denver to Knoxville?

  • What is the most popular airline from Denver to Knoxville?

Best airlines flying from Denver to Knoxville

Compare and see reviews for airlines that fly from Denver to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $66Free CancellationRating
7.2
694 reviews
Search Allegiant Air flights
FrontierPriceFrom $78Free CancellationRating
5.8
3,130 reviews
Search Frontier flights
DeltaPriceFrom $197Free CancellationRating
7.9
7,979 reviews
Search Delta flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
11,028 reviews
Search American Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
8,988 reviews
Search United Airlines flights

  • United Airlines Flights From Denver to Knoxville

    United Airlines operates around 8 flights from Denver to Knoxville every week. The average price of these flights found in the last 72 hours has been $437, but momondo users have found United Airlines deals from Denver to Knoxville from as low as $233 round-trip. United Airlines has been scored 7.4/10 in 8,988 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Denver to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Denver to Knoxville.

I’m not ready to book a flight from Denver to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Denver are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 11/21
Fri 11/28
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States