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Cheap flights from Denver to Knoxville from $49

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Knoxville departing on 10/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Denver to Knoxville (DEN-TYS)

Cheap round-trip flights

Allegiant Air Logo
8:56 am - 1:43 pmDEN-TYS
2h 47mnonstop
Allegiant Air Logo
7:00 am - 8:06 amTYS-DEN
3h 06mnonstop
$88Allegiant Air
Find Deal
Thu, Sep 25 - Sun, Sep 28
Allegiant Air Logo
8:56 am - 1:43 pmDEN-TYS
2h 47mnonstop
Allegiant Air Logo
7:00 am - 8:06 amTYS-DEN
3h 06mnonstop
$92Allegiant Air
Find Deal
Thu, Sep 4 - Sun, Sep 7
Allegiant Air Logo
8:56 am - 1:43 pmDEN-TYS
2h 47mnonstop
Allegiant Air Logo
7:00 am - 8:06 amTYS-DEN
3h 06mnonstop
$96Allegiant Air
Find Deal
Sun, Sep 7 - Sun, Sep 14
Frontier Logo
2:52 pm - 7:41 pmDEN-TYS
2h 49mnonstop
Frontier Logo
5:08 pm - 6:15 pmTYS-DEN
3h 07mnonstop
$101Frontier
Find Deal
Sun, Aug 24 - Sun, Sep 7
Logo
3:03 pm - 7:50 pmDEN-TYS
2h 47mnonstop
Logo
7:00 am - 8:06 amTYS-DEN
3h 06mnonstop
$118
Find Deal
Thu, Sep 4 - Sun, Sep 7
Allegiant Air Logo
8:56 am - 1:43 pmDEN-TYS
2h 47mnonstop
Allegiant Air Logo
7:00 am - 8:06 amTYS-DEN
3h 06mnonstop
$123Allegiant Air
Find Deal
Thu, Sep 4 - Sun, Sep 7
Allegiant Air Logo
8:54 am - 1:33 pmDEN-TYS
2h 39mnonstop
Allegiant Air Logo
7:00 am - 8:04 amTYS-DEN
3h 04mnonstop
$125Allegiant Air
Find Deal
Thu, Oct 23 - Sun, Oct 26
Frontier Logo
2:59 pm - 7:45 pmDEN-TYS
2h 46mnonstop
Frontier Logo
8:35 pm - 9:44 pmTYS-DEN
3h 09mnonstop
$146Frontier
Find Deal
Mon, Sep 8 - Mon, Sep 15
Logo
8:30 pm - 10:21 pmDEN-TYS
23h 51m1 stop
Logo
7:00 am - 8:06 amTYS-DEN
3h 06mnonstop
$183
Find Deal
Thu, Sep 4 - Sun, Sep 7
American Airlines Logo
6:15 am - 3:19 pmDEN-TYS
7h 04m1 stop
American Airlines Logo
6:18 pm - 9:47 pmTYS-DEN
5h 29m1 stop
$219American Airlines
Find Deal
Sat, Dec 6 - Sat, Dec 13

American Airlines flights from Denver to Knoxville

Our best American Airlines deals on Denver to Knoxville flight tickets
American Airlines
Dec 6
DEN6:15 amDenver Intl
7h 04m
1 stop
TYS3:19 pmKnoxville McGhee Tyson
Dec 13
TYS6:18 pmKnoxville McGhee Tyson
5h 29m
1 stop
DEN9:47 pmDenver Intl
$219
Find similar
American Airlines
Aug 24
DEN5:00 amDenver Intl
6h 38m
1 stop
TYS1:38 pmKnoxville McGhee Tyson
Sep 9
TYS2:07 pmKnoxville McGhee Tyson
7h 40m
1 stop
DEN7:47 pmDenver Intl
$304
Find similar
American Airlines
Aug 28
DEN2:09 pmDenver Intl
7h 37m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
Sep 2
TYS6:39 pmKnoxville McGhee Tyson
5h 36m
1 stop
DEN10:15 pmDenver Intl
$308
Find similar

Frontier flights from Denver to Knoxville

Our best Frontier deals on Denver to Knoxville flight tickets
Frontier
Aug 24
DEN2:52 pmDenver Intl
2h 49m
TYS7:41 pmKnoxville McGhee Tyson
Sep 7
TYS5:08 pmKnoxville McGhee Tyson
3h 07m
DEN6:15 pmDenver Intl
$101
Find similar
Frontier
Aug 21
DEN2:52 pmDenver Intl
2h 49m
TYS7:41 pmKnoxville McGhee Tyson
Aug 24
TYS8:33 pmKnoxville McGhee Tyson
3h 11m
DEN9:44 pmDenver Intl
$115
Find similar
Frontier
Aug 21
DEN2:52 pmDenver Intl
2h 49m
TYS7:41 pmKnoxville McGhee Tyson
Aug 24
TYS8:33 pmKnoxville McGhee Tyson
3h 11m
DEN9:44 pmDenver Intl
$130
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/25

8:56 am-1:43 pm

Nonstop2h 47m

Knoxville McGhee Tyson

Sun 9/28

7:00 am-8:06 am

Nonstop3h 06m

$88

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/4

8:56 am-1:43 pm

Nonstop2h 47m

Knoxville McGhee Tyson

Sun 9/7

7:00 am-8:06 am

Nonstop3h 06m

$92

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 9/7

8:56 am-1:43 pm

Nonstop2h 47m

Knoxville McGhee Tyson

Sun 9/14

7:00 am-8:06 am

Nonstop3h 06m

$96

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 8/24

2:52 pm-7:41 pm

Nonstop2h 49m

Knoxville McGhee Tyson

Sun 9/7

5:08 pm-6:15 pm

Nonstop3h 07m

$101

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/4

3:03 pm-7:50 pm

Nonstop2h 47m

Knoxville McGhee Tyson

Sun 9/7

7:00 am-8:06 am

Nonstop3h 06m

$118

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/4

8:56 am-1:43 pm

Nonstop2h 47m

Knoxville McGhee Tyson

Sun 9/7

7:00 am-8:06 am

Nonstop3h 06m

$123

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 10/23

8:54 am-1:33 pm

Nonstop2h 39m

Knoxville McGhee Tyson

Sun 10/26

7:00 am-8:04 am

Nonstop3h 04m

$125

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 9/8

2:59 pm-7:45 pm

Nonstop2h 46m

Knoxville McGhee Tyson

Mon 9/15

8:35 pm-9:44 pm

Nonstop3h 09m

$146

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/4

8:30 pm-10:21 pm

1 stop23h 51m

Knoxville McGhee Tyson

Sun 9/7

7:00 am-8:06 am

Nonstop3h 06m

$183

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sat 12/6

6:15 am-3:19 pm

1 stop7h 04m

Knoxville McGhee Tyson

Sat 12/13

6:18 pm-9:47 pm

1 stop5h 29m

$219

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Denver to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Denver, with most prices found around $179. If you aren’t able to travel during the month of August, then book flights to Knoxville from Denver during April instead. Flights to Knoxville in April, while not as cheap as those in August, still average around $204.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Denver to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $163. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Denver to Knoxville for around $411.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Denver to Knoxville when you can find flight prices for as low as $127. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $253.

What is the cheapest Denver Intl to Knoxville McGhee Tyson flight route?

Fly from Denver Intl to Knoxville McGhee Tyson for the best Denver Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $256 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Denver for as low as $180 on momondo.

What cabin class options are available on Denver Intl to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Denver Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Denver to Knoxville flight prices changed over time?

As of August 2025, prices for Denver to Knoxville flights are approximately 26% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Knoxville (DEN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Knoxville

Best Price Found

$49

Fastest flight time

2h 38m

Direct flights

Mon, Tue, Wed, Fri and Sat

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Denver in the past 72 hours is $49. The best round-trip flight deal from Denver to Knoxville found on momondo in the last 72 hours is $88.
The fastest flight from Denver to Knoxville takes 2h 38m
Direct flights go from Denver to Knoxville on Monday, Tuesday, Wednesday, Friday and Saturday. Airlines offering direct flights are: United Airlines, Allegiant Air and Frontier.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Denver Intl to Knoxville McGhee Tyson by plane?

    Denver Intl and Knoxville McGhee Tyson are 1174.7 mi apart from one another. Flights usually cover this in 2h 39m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Denver Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Denver Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Denver to Knoxville?

  • What is the most popular airline from Denver to Knoxville?

Best airlines flying from Denver to Knoxville

Compare and see reviews for airlines that fly from Denver to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $63Free CancellationRating
5.8
3,219 reviews
Search Frontier flights
Allegiant AirPriceFrom $72Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $233Free CancellationRating
7.4
8,916 reviews
Search United Airlines flights
DeltaPriceFrom $248Free CancellationRating
8.0
7,980 reviews
Search Delta flights

  • United Airlines Flights From Denver to Knoxville

    United Airlines operates around 11 flights from Denver to Knoxville every week. The average price of these flights found in the last 72 hours has been $462, but momondo users have found United Airlines deals from Denver to Knoxville from as low as $233 round-trip. United Airlines has been scored 7.4/10 in 8,916 reviews.

  • Allegiant Air Flights From Denver to Knoxville

    Allegiant Air is also a popular choice for this route. Allegiant Air flight deals for Denver to Knoxville start from as low as $72 round-trip, depending on your selected dates, with average Allegiant Air deals seen on momondo around $130. Allegiant Air operates 1 flight to Knoxville from Denver in an average week. Users have rated it 7.2/10 across 701 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Lenoir City
Alcoa
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Denver to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Denver to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Denver to Knoxville.

I’m not ready to book a flight from Denver to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Denver are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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