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Cheap flights from Denver to Greenville from $145

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:08 am - 9:32 amDEN  Denver Intl-GSP Greenville
22h 24m1 stop Tampa
Multiple Airlines Logo
8:52 pm - 9:55 pmGSP  Greenville-DEN Denver Intl
27h 03m2 stops Tampa Dallas/Fort Worth
$235Multiple Airlines
Wed, Dec 9 - Mon, Dec 14
Multiple Airlines Logo
9:08 am - 3:29 pmDEN  Denver Intl-GSP Greenville
28h 21m1 stop Tampa
Multiple Airlines Logo
8:52 pm - 9:55 pmGSP  Greenville-DEN Denver Intl
27h 03m2 stops Tampa Dallas/Fort Worth
$245Multiple Airlines
Mon, Dec 7 - Mon, Dec 14
Southwest Logo
8:25 am - 6:10 pmDEN  Denver Intl-GSP Greenville
7h 45m2 stops Houston Hobby Nashville Intl
Southwest Logo
6:45 pm - 10:40 pmGSP  Greenville-DEN Denver Intl
5h 55m1 stop Nashville Intl
$334Southwest
Wed, Dec 9 - Tue, Dec 15
Southwest Logo
10:55 am - 8:50 pmDEN  Denver Intl-GSP Greenville
7h 55m2 stops Memphis Nashville Intl
Southwest Logo
7:05 am - 1:35 pmGSP  Greenville-DEN Denver Intl
8h 30m2 stops Nashville Intl Dallas Love Field
$339Southwest
Wed, Dec 9 - Tue, Dec 15
United Airlines Logo
10:10 am - 3:12 pmDEN  Denver Intl-GSP Greenville
3h 02mnonstop
United Airlines Logo
5:00 pm - 10:24 pmGSP  Greenville-DEN Denver Intl
7h 24m1 stop Houston George Bush Intcntl
$354United Airlines
Wed, Dec 9 - Tue, Dec 15
United Airlines Logo
7:40 am - 3:17 pmDEN  Denver Intl-GSP Greenville
5h 37m1 stop Houston George Bush Intcntl
United Airlines Logo
4:18 pm - 5:55 pmGSP  Greenville-DEN Denver Intl
3h 37mnonstop
$379United Airlines
Tue, Dec 1 - Wed, Dec 9
American Airlines Logo
10:12 am - 7:51 pmDEN  Denver Intl-GSP Greenville
7h 39m1 stop Charlotte Douglas
American Airlines Logo
7:44 pm - 11:50 pmGSP  Greenville-DEN Denver Intl
6h 06m1 stop Dallas/Fort Worth
$379American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
5:17 am - 1:23 pmDEN  Denver Intl-GSP Greenville
6h 06m1 stop Dallas/Fort Worth
American Airlines Logo
7:45 am - 12:23 pmGSP  Greenville-DEN Denver Intl
6h 38m1 stop Dallas/Fort Worth
$379American Airlines
Wed, Dec 9 - Tue, Dec 15
Delta Logo
6:05 am - 2:49 pmDEN  Denver Intl-GSP Greenville
6h 44m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:14 am - 2:16 pmGSP  Greenville-DEN Denver Intl
6h 02m1 stop Atlanta Hartsfield-Jackson
$399Delta
Thu, Mar 25 - Thu, Apr 8
Delta Logo
1:14 pm - 7:56 pmDEN  Denver Intl-GSP Greenville
4h 42m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:57 am - 5:14 pmGSP  Greenville-DEN Denver Intl
8h 17m1 stop Detroit Metropolitan Wayne County
$399Delta
Tue, Dec 8 - Sun, Dec 13

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United Airlines flights from Denver to Greenville

Our best United Airlines deals on Denver to Greenville flight tickets
United Airlines
Dec 9
DEN10:10 amDenver Intl
3h 02m
GSP3:12 pmGreenville
Dec 15
GSP5:00 pmGreenville
7h 24m
1 stop
DEN10:24 pmDenver Intl
$354
United Airlines
Dec 1
DEN7:45 amDenver Intl
7h 08m
1 stop
GSP4:53 pmGreenville
Dec 8
GSP4:18 pmGreenville
3h 37m
DEN5:55 pmDenver Intl
$379
United Airlines
Nov 25
DEN6:00 amDenver Intl
6h 16m
1 stop
GSP2:16 pmGreenville
Dec 3
GSP4:18 pmGreenville
3h 37m
DEN5:55 pmDenver Intl
$383

Southwest flights from Denver to Greenville

Our best Southwest deals on Denver to Greenville flight tickets
Southwest
Dec 9
DEN10:55 amDenver Intl
7h 55m
2 stops
GSP8:50 pmGreenville
Dec 15
GSP7:05 amGreenville
8h 30m
2 stops
DEN1:35 pmDenver Intl
$339
Southwest
Dec 1
DEN10:55 amDenver Intl
7h 55m
2 stops
GSP8:50 pmGreenville
Dec 5
GSP7:05 amGreenville
5h 30m
1 stop
DEN10:35 amDenver Intl
$384
Southwest
Dec 7
DEN10:55 amDenver Intl
7h 55m
2 stops
GSP8:50 pmGreenville
Dec 17
GSP8:15 amGreenville
7h 45m
2 stops
DEN2:00 pmDenver Intl
$387

momondo Fare Finder

 
Use the filters below to find and compare flights from Denver to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Wed 12/9

9:08 am-9:32 am

1 stop22h 24m

Greenville

Mon 12/14

8:52 pm-9:55 pm

2 stops27h 03m

$235

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Mon 12/7

9:08 am-3:29 pm

1 stop28h 21m

Greenville

Mon 12/14

8:52 pm-9:55 pm

2 stops27h 03m

$245

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Wed 12/9

8:25 am-6:10 pm

2 stops7h 45m

Greenville

Tue 12/15

6:45 pm-10:40 pm

1 stop5h 55m

$334

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Wed 12/9

10:55 am-8:50 pm

2 stops7h 55m

Greenville

Tue 12/15

7:05 am-1:35 pm

2 stops8h 30m

$339

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Wed 12/9

10:10 am-3:12 pm

Nonstop3h 02m

Greenville

Tue 12/15

5:00 pm-10:24 pm

1 stop7h 24m

$354
Quickest round-trip

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Tue 12/1

7:40 am-3:17 pm

1 stop5h 37m

Greenville

Wed 12/9

4:18 pm-5:55 pm

Nonstop3h 37m

$379

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Thu 12/3

10:12 am-7:51 pm

1 stop7h 39m

Greenville

Mon 12/7

7:44 pm-11:50 pm

1 stop6h 06m

$379

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Wed 12/9

5:17 am-1:23 pm

1 stop6h 06m

Greenville

Tue 12/15

7:45 am-12:23 pm

1 stop6h 38m

$379

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Thu 3/25

6:05 am-2:49 pm

1 stop6h 44m

Greenville

Thu 4/8

10:14 am-2:16 pm

1 stop6h 02m

$399

DenverGreenville

DEN Denver Intl - GSP Greenville

DENGSP

Denver Intl

Tue 12/8

1:14 pm-7:56 pm

1 stop4h 42m

Greenville

Sun 12/13

10:57 am-5:14 pm

1 stop8h 17m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Denver to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $359 to $539.
The lowest price recently found on this route was $235.

What is the cheapest month to fly to Greenville?

The month of March is another great option to travel to Greenville, with average flight prices from Denver averaging around $358.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Denver. The lowest ticket price found for a Saturday departure recently was $389. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $567. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest Denver Intl to Greenville flight route?

Fly from Denver Intl to Greenville for the best Denver Intl - Greenville flight prices

How far in advance should I book a flight from Denver to Greenville?

You are more likely to see cheaper flights to Greenville from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $399 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Denver for as low as $268 on momondo.

What cabin class options are available on Denver to Greenville flights?

There are 4 cabin classes available to choose from on Denver to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Greenville flights?

You could potentially save up to 12% on your flight if you consider stops on a Denver to Greenville flight.

How have Denver to Greenville flight prices changed over time?

As of November 2026, prices for Denver to Greenville flights are approximately 72% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Greenville (DEN to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Greenville

Best Price Found

$145

Fastest flight time

3h 02m

Direct flights

Every day

Airports in Greenville

1 airport
The best one-way flight to Greenville from Denver in the past 72 hours is $145. The best round-trip flight deal from Denver to Greenville found on momondo in the last 72 hours is $235.
The fastest flight from Denver to Greenville takes 3h 02m
Direct flights go from Denver to Greenville every day.
There is 1 airport in Greenville. From Denver there are direct flights to Greenville (GSP).
Search flight deals

Frequently asked questions about flying from Denver to Greenville

  • How far is Denver Intl to Greenville by plane?

    The straight-line distance from Denver Intl to Greenville is 1282.0 mi. In terms of flight time, this usually takes a little over 3h 02m.

  • When did momondo last update prices for flights from Denver Intl Airport to Greenville Airport?

    Prices for flights from Denver Intl Airport to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Denver Intl Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Denver to Greenville?

  • What is the most popular airline from Denver to Greenville?

Best airlines flying from Denver to Greenville

Compare and see reviews for airlines that fly from Denver to Greenville with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $241Free CancellationRating
7.1
3,065 reviews
Search JetBlue flights
United AirlinesPriceFrom $249Free CancellationRating
7.3
10,460 reviews
Search United Airlines flights
American AirlinesPriceFrom $268Free CancellationRating
7.0
12,228 reviews
Search American Airlines flights
DeltaPriceFrom $268Free CancellationRating
7.8
8,699 reviews
Search Delta flights
SouthwestPriceFrom $285Free CancellationRating
8.0
4,215 reviews
Search Southwest flights

  • United Airlines Flights From Denver to Greenville

    The lowest priced United Airlines flight from Denver to Greenville from the last 72 hours was $249. Generally, United Airlines has 3 flights on this route every week with an average price of $437. United Airlines is rated 7.3/10 by our users.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Greenwood
Simpsonville
Greer
Duncan
Seneca

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Greenville?

Finding the right flight to Greenville from Denver is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from Denver to Greenville with flexible booking policies on momondo?

Flights from Denver to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Denver to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from Denver.

I’m not ready to book a flight from Denver to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Denver to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

An easier way to manage your Greenville trip

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