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Cheap flights from Columbus to Key West from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to Key West departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:15 am - 1:30 pm
CMH
-
EYW
7h 15m
1 stop
Spirit Airlines Logo
2:25 pm - 11:32 pm
EYW
-
CMH
9h 07m
1 stop
$209Spirit Airlines
Mon, Mar 2 - Thu, Mar 5
Multiple Airlines Logo
6:15 am - 1:30 pm
CMH
-
EYW
7h 15m
1 stop
Multiple Airlines Logo
4:14 pm - 8:30 am
EYW
-
CMH
16h 16m
1 stop
$211Multiple Airlines
Mon, Mar 2 - Thu, Mar 5
Spirit Airlines Logo
5:45 am - 11:30 am
CMH
-
EYW
5h 45m
1 stop
Spirit Airlines Logo
12:25 pm - 10:49 pm
EYW
-
CMH
10h 24m
1 stop
$221Spirit Airlines
Wed, Apr 1 - Wed, Apr 8
Spirit Airlines Logo
6:15 am - 1:30 pm
CMH
-
EYW
7h 15m
1 stop
Spirit Airlines Logo
2:25 pm - 11:32 pm
EYW
-
CMH
9h 07m
1 stop
$229Spirit Airlines
Mon, Feb 23 - Thu, Feb 26
Multiple Airlines Logo
11:45 am - 9:06 am
CMH
-
EYW
21h 21m
1 stop
Multiple Airlines Logo
9:46 am - 8:30 am
EYW
-
CMH
22h 44m
1 stop
$232Multiple Airlines
Wed, Mar 11 - Sun, Mar 15
Multiple Airlines Logo
6:15 am - 1:30 pm
CMH
-
EYW
7h 15m
1 stop
Multiple Airlines Logo
9:46 am - 8:30 am
EYW
-
CMH
22h 44m
1 stop
$234Multiple Airlines
Mon, Mar 2 - Thu, Mar 5
Multiple Airlines Logo
11:19 am - 12:21 pm
CMH
-
EYW
25h 02m
2 stops
Multiple Airlines Logo
9:46 am - 8:30 am
EYW
-
CMH
22h 44m
1 stop
$236Multiple Airlines
Mon, Mar 2 - Thu, Mar 5
Multiple Airlines Logo
5:45 am - 3:24 pm
CMH
-
EYW
9h 39m
1 stop
Multiple Airlines Logo
1:06 pm - 8:30 am
EYW
-
CMH
19h 24m
1 stop
$240Multiple Airlines
Thu, Mar 5 - Mon, Mar 9
Spirit Airlines Logo
10:40 am - 11:30 am
CMH
-
EYW
24h 50m
1 stop
Spirit Airlines Logo
2:35 pm - 9:41 am
EYW
-
CMH
19h 06m
1 stop
$241Spirit Airlines
Wed, Apr 8 - Mon, Apr 13
Multiple Airlines Logo
6:05 am - 3:51 pm
CMH
-
EYW
9h 46m
1 stop
Multiple Airlines Logo
12:25 pm - 10:49 pm
EYW
-
CMH
10h 24m
1 stop
$242Multiple Airlines
Sun, Mar 22 - Wed, Mar 25

Delta flights from Columbus to Key West

Our best Delta deals on Columbus to Key West flight tickets
Delta
Mar 3
CMH12:39 pmColumbus
7h 03m
1 stop
EYW7:42 pmKey West
Mar 10
EYW1:22 pmKey West
8h 33m
1 stop
CMH9:55 pmColumbus
$251
Delta
Apr 11
CMH1:05 pmColumbus
6h 36m
1 stop
EYW7:41 pmKey West
Apr 18
EYW7:33 amKey West
6h 21m
1 stop
CMH1:54 pmColumbus
$265
Delta
Feb 21
CMH12:32 pmColumbus
7h 10m
1 stop
EYW7:42 pmKey West
Feb 26
EYW5:56 pmKey West
4h 31m
1 stop
CMH10:27 pmColumbus
$294

American Airlines flights from Columbus to Key West

Our best American Airlines deals on Columbus to Key West flight tickets
American Airlines
Mar 3
CMH6:00 amColumbus
7h 15m
2 stops
EYW1:15 pmKey West
Mar 10
EYW7:42 pmKey West
5h 17m
1 stop
CMH12:59 amColumbus
$256
American Airlines
Mar 4
CMH6:19 amColumbus
5h 13m
1 stop
EYW11:32 amKey West
Mar 11
EYW7:42 pmKey West
5h 17m
1 stop
CMH12:59 amColumbus
$279
American Airlines
Feb 23
CMH6:18 amColumbus
4h 53m
1 stop
EYW11:11 amKey West
Mar 3
EYW7:45 pmKey West
5h 14m
1 stop
CMH12:59 amColumbus
$280

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Columbus to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/2

6:15 am-1:30 pm

1 stop7h 15m

Key West

Thu 3/5

2:25 pm-11:32 pm

1 stop9h 07m

$209

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/2

6:15 am-1:30 pm

1 stop7h 15m

Key West

Thu 3/5

4:14 pm-8:30 am

1 stop16h 16m

$211

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 4/1

5:45 am-11:30 am

1 stop5h 45m

Key West

Wed 4/8

12:25 pm-10:49 pm

1 stop10h 24m

$221

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 2/23

6:15 am-1:30 pm

1 stop7h 15m

Key West

Thu 2/26

2:25 pm-11:32 pm

1 stop9h 07m

$229

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 3/11

11:45 am-9:06 am

1 stop21h 21m

Key West

Sun 3/15

9:46 am-8:30 am

1 stop22h 44m

$232

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/2

6:15 am-1:30 pm

1 stop7h 15m

Key West

Thu 3/5

9:46 am-8:30 am

1 stop22h 44m

$234

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/2

11:19 am-12:21 pm

2 stops25h 02m

Key West

Thu 3/5

9:46 am-8:30 am

1 stop22h 44m

$236

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Thu 3/5

5:45 am-3:24 pm

1 stop9h 39m

Key West

Mon 3/9

1:06 pm-8:30 am

1 stop19h 24m

$240

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 4/8

10:40 am-11:30 am

1 stop24h 50m

Key West

Mon 4/13

2:35 pm-9:41 am

1 stop19h 06m

$241

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/22

6:05 am-3:51 pm

1 stop9h 46m

Key West

Wed 3/25

12:25 pm-10:49 pm

1 stop10h 24m

$242

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbus to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Columbus to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $311. If you are unable to visit Key West during the month of September, then departing from Columbus during the month January is also very affordable. Most momondo users find prices during this month for around $321.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Columbus when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $391 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Columbus for as low as $268 on momondo.

Cheap Columbus to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Key West

Fastest flight time

4h 52m

Direct flights

None
The fastest flight from Columbus to Key West takes 4h 52m
There are no direct flights from Columbus to Key West. There are no popular flight routes from Columbus to Key West.
Search flight deals

  • How far is Columbus to Key West by plane?

    Columbus and Key West are 1066.3 mi apart from one another. Flights usually cover this in 4h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbus to Key West Airport?

    Prices for flights from Columbus to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus to Key West Airport?

  • How old do you have to be to fly from Columbus to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Columbus to Key West

Compare and see reviews for airlines that fly from Columbus to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $96Free CancellationRating
6.3
8,430 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $145Free CancellationRating
7.4
9,254 reviews
Search United Airlines flights
DeltaPriceFrom $228Free CancellationRating
7.9
8,172 reviews
Search Delta flights
American AirlinesPriceFrom $254Free CancellationRating
7.2
11,249 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Key West?

It is quick and easy to find Columbus to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbus to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Columbus on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbus to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Columbus.

I’m not ready to book a flight from Columbus to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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