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Cheap flights from Columbus to Key West from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to Key West departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:45 am - 12:26 pm
CMH
-
EYW
6h 41m
1 stop
Multiple Airlines Logo
9:49 am - 11:42 am
EYW
-
CMH
25h 53m
2 stops
$243Multiple Airlines
Mon, Mar 2 - Mon, Mar 9
Delta Logo
1:00 pm - 7:41 pm
CMH
-
EYW
6h 41m
1 stop
Delta Logo
6:25 pm - 12:24 am
EYW
-
CMH
5h 59m
1 stop
$251Delta
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
11:55 am - 7:12 pm
CMH
-
EYW
7h 17m
2 stops
American Airlines Logo
2:26 pm - 8:59 pm
EYW
-
CMH
6h 33m
1 stop
$256American Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
1:25 pm - 9:06 am
CMH
-
EYW
19h 41m
1 stop
Multiple Airlines Logo
1:01 pm - 7:59 am
EYW
-
CMH
42h 58m
2 stops
$258Multiple Airlines
Wed, Mar 4 - Tue, Mar 10
Multiple Airlines Logo
2:51 pm - 12:26 pm
CMH
-
EYW
21h 35m
2 stops
Multiple Airlines Logo
11:51 am - 11:53 pm
EYW
-
CMH
12h 02m
1 stop
$260Multiple Airlines
Sun, Mar 8 - Wed, Mar 11
American Airlines Logo
2:36 pm - 10:18 pm
CMH
-
EYW
7h 42m
2 stops
American Airlines Logo
3:56 pm - 12:26 am
EYW
-
CMH
8h 30m
2 stops
$261American Airlines
Tue, Mar 10 - Wed, Mar 18
Multiple Airlines Logo
2:51 pm - 12:26 pm
CMH
-
EYW
21h 35m
2 stops
Multiple Airlines Logo
11:51 am - 8:45 am
EYW
-
CMH
20h 54m
1 stop
$264Multiple Airlines
Sun, Mar 8 - Wed, Mar 11
Delta Logo
3:00 pm - 7:40 pm
CMH
-
EYW
4h 40m
1 stop
Delta Logo
6:22 pm - 12:36 am
EYW
-
CMH
6h 14m
1 stop
$265Delta
Sat, May 2 - Thu, May 7
Multiple Airlines Logo
5:45 am - 12:26 pm
CMH
-
EYW
6h 41m
1 stop
Multiple Airlines Logo
1:06 pm - 8:30 am
EYW
-
CMH
19h 24m
1 stop
$270Multiple Airlines
Mon, Mar 2 - Mon, Mar 9
Spirit Airlines Logo
6:00 am - 11:11 am
CMH
-
EYW
5h 11m
1 stop
Spirit Airlines Logo
12:06 pm - 9:52 pm
EYW
-
CMH
9h 46m
1 stop
$271Spirit Airlines
Sun, May 3 - Thu, May 7

Delta flights from Columbus to Key West

Our best Delta deals on Columbus to Key West flight tickets
Delta
Mar 18
CMH1:00 pmColumbus
6h 41m
1 stop
EYW7:41 pmKey West
Mar 25
EYW6:25 pmKey West
5h 59m
1 stop
CMH12:24 amColumbus
$251
Delta
May 2
CMH3:00 pmColumbus
4h 40m
1 stop
EYW7:40 pmKey West
May 7
EYW6:22 pmKey West
6h 14m
1 stop
CMH12:36 amColumbus
$265
Delta
Mar 4
CMH6:10 amColumbus
6h 35m
1 stop
EYW12:45 pmKey West
Mar 11
EYW6:25 pmKey West
5h 59m
1 stop
CMH12:24 amColumbus
$280

American Airlines flights from Columbus to Key West

Our best American Airlines deals on Columbus to Key West flight tickets
American Airlines
Mar 18
CMH11:55 amColumbus
7h 17m
2 stops
EYW7:12 pmKey West
Mar 25
EYW2:26 pmKey West
6h 33m
1 stop
CMH8:59 pmColumbus
$256
American Airlines
Mar 10
CMH2:36 pmColumbus
7h 42m
2 stops
EYW10:18 pmKey West
Mar 18
EYW3:56 pmKey West
8h 30m
2 stops
CMH12:26 amColumbus
$261
American Airlines
Apr 21
CMH8:08 amColumbus
8h 22m
2 stops
EYW4:30 pmKey West
Apr 28
EYW2:29 pmKey West
9h 02m
1 stop
CMH11:31 pmColumbus
$290

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Columbus to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/2

5:45 am-12:26 pm

1 stop6h 41m

Key West

Mon 3/9

9:49 am-11:42 am

2 stops25h 53m

$243

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 3/18

1:00 pm-7:41 pm

1 stop6h 41m

Key West

Wed 3/25

6:25 pm-12:24 am

1 stop5h 59m

$251

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 3/18

11:55 am-7:12 pm

2 stops7h 17m

Key West

Wed 3/25

2:26 pm-8:59 pm

1 stop6h 33m

$256

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 3/4

1:25 pm-9:06 am

1 stop19h 41m

Key West

Tue 3/10

1:01 pm-7:59 am

2 stops42h 58m

$258

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/8

2:51 pm-12:26 pm

2 stops21h 35m

Key West

Wed 3/11

11:51 am-11:53 pm

1 stop12h 02m

$260

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 3/10

2:36 pm-10:18 pm

2 stops7h 42m

Key West

Wed 3/18

3:56 pm-12:26 am

2 stops8h 30m

$261

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/8

2:51 pm-12:26 pm

2 stops21h 35m

Key West

Wed 3/11

11:51 am-8:45 am

1 stop20h 54m

$264

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sat 5/2

3:00 pm-7:40 pm

1 stop4h 40m

Key West

Thu 5/7

6:22 pm-12:36 am

1 stop6h 14m

$265

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/2

5:45 am-12:26 pm

1 stop6h 41m

Key West

Mon 3/9

1:06 pm-8:30 am

1 stop19h 24m

$270

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 5/3

6:00 am-11:11 am

1 stop5h 11m

Key West

Thu 5/7

12:06 pm-9:52 pm

1 stop9h 46m

$271

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbus to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Columbus to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $309. If you are unable to visit Key West during the month of September, then departing from Columbus during the month February is also very affordable. Most momondo users find prices during this month for around $319.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Columbus when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $382 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Columbus for as low as $268 on momondo.

Cheap Columbus to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Key West

Fastest flight time

4h 40m

Direct flights

None
The fastest flight from Columbus to Key West takes 4h 40m
There are no direct flights from Columbus to Key West. There are no popular flight routes from Columbus to Key West.
Search flight deals

  • How far is Columbus to Key West by plane?

    Columbus and Key West are 1066.3 mi apart from one another. Flights usually cover this in 4h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbus to Key West Airport?

    Prices for flights from Columbus to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus to Key West Airport?

  • How old do you have to be to fly from Columbus to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Columbus to Key West

Compare and see reviews for airlines that fly from Columbus to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $96Free CancellationRating
6.3
8,482 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $165Free CancellationRating
7.4
9,335 reviews
Search United Airlines flights
DeltaPriceFrom $250Free CancellationRating
7.9
8,228 reviews
Search Delta flights
American AirlinesPriceFrom $253Free CancellationRating
7.2
11,334 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Key West?

It is quick and easy to find Columbus to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbus to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Columbus on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbus to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Columbus.

I’m not ready to book a flight from Columbus to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

An easier way to manage your Key West trip

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