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Cheap flights from Columbus to Key West from $129

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to Key West departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:21 pm - 12:26 pm
CMH
-
EYW
15h 05m
1 stop
Multiple Airlines Logo
11:51 am - 9:43 am
EYW
-
CMH
21h 52m
1 stop
$203Multiple Airlines
Sun, Apr 26 - Wed, Apr 29
Multiple Airlines Logo
12:10 pm - 12:21 pm
CMH
-
EYW
24h 11m
2 stops
Multiple Airlines Logo
9:46 am - 8:16 pm
EYW
-
CMH
10h 30m
1 stop
$214Multiple Airlines
Mon, Apr 20 - Thu, Apr 23
Multiple Airlines Logo
7:00 pm - 12:26 pm
CMH
-
EYW
17h 26m
2 stops
Multiple Airlines Logo
11:51 am - 9:43 am
EYW
-
CMH
21h 52m
1 stop
$225Multiple Airlines
Sun, Apr 19 - Wed, Apr 22
Delta Logo
12:49 pm - 7:40 pm
CMH
-
EYW
6h 51m
1 stop
Delta Logo
6:19 pm - 12:25 am
EYW
-
CMH
6h 06m
1 stop
$247Delta
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
7:00 pm - 2:43 pm
CMH
-
EYW
19h 43m
2 stops
Multiple Airlines Logo
11:51 am - 9:43 am
EYW
-
CMH
21h 52m
1 stop
$248Multiple Airlines
Sun, Apr 26 - Wed, Apr 29
American Airlines Logo
2:52 pm - 10:36 pm
CMH
-
EYW
7h 44m
2 stops
American Airlines Logo
2:29 pm - 11:39 pm
EYW
-
CMH
9h 10m
1 stop
$252American Airlines
Sat, May 16 - Wed, May 20
Multiple Airlines Logo
8:39 am - 10:24 am
CMH
-
EYW
25h 45m
1 stop
Multiple Airlines Logo
11:51 am - 9:43 am
EYW
-
CMH
21h 52m
1 stop
$255Multiple Airlines
Sun, Apr 19 - Wed, Apr 22
Multiple Airlines Logo
8:30 pm - 9:06 am
CMH
-
EYW
12h 36m
1 stop
Multiple Airlines Logo
11:54 am - 5:10 pm
EYW
-
CMH
29h 16m
2 stops
$257Multiple Airlines
Sat, May 2 - Sat, May 9
Multiple Airlines Logo
8:39 am - 10:24 am
CMH
-
EYW
25h 45m
1 stop
Multiple Airlines Logo
11:01 am - 5:40 pm
EYW
-
CMH
30h 39m
2 stops
$264Multiple Airlines
Sun, Apr 19 - Thu, Apr 23
Multiple Airlines Logo
8:30 pm - 9:06 am
CMH
-
EYW
12h 36m
1 stop
Multiple Airlines Logo
12:07 pm - 7:53 pm
EYW
-
CMH
7h 46m
1 stop
$266Multiple Airlines
Sat, May 2 - Fri, May 8

Spirit Airlines flights from Columbus to Key West

Our best Spirit Airlines deals on Columbus to Key West flight tickets
Spirit Airlines
Apr 20
CMH6:00 amColumbus
7h 35m
1 stop
EYW1:35 pmKey West
Apr 23
EYW12:26 pmKey West
10h 06m
1 stop
CMH10:32 pmColumbus
$309
Spirit Airlines
Apr 19
CMH6:00 amColumbus
5h 31m
1 stop
EYW11:31 amKey West
Apr 23
EYW12:26 pmKey West
31h 50m
3 stops
CMH8:16 pmColumbus
$445
Spirit Airlines
Apr 20
CMH6:00 amColumbus
7h 35m
1 stop
EYW1:35 pmKey West
Apr 24
EYW2:30 pmKey West
29h 05m
3 stops
CMH7:35 pmColumbus
$517

Delta flights from Columbus to Key West

Our best Delta deals on Columbus to Key West flight tickets
Delta
May 5
CMH12:49 pmColumbus
6h 51m
1 stop
EYW7:40 pmKey West
May 12
EYW6:19 pmKey West
6h 06m
1 stop
CMH12:25 amColumbus
$247
Delta
May 16
CMH2:20 pmColumbus
5h 29m
1 stop
EYW7:49 pmKey West
May 19
EYW2:32 pmKey West
7h 28m
1 stop
CMH10:00 pmColumbus
$283
Delta
May 12
CMH6:05 amColumbus
4h 48m
1 stop
EYW10:53 amKey West
May 12
EYW6:19 pmKey West
6h 06m
1 stop
CMH12:25 amColumbus
$291

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Columbus to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/26

9:21 pm-12:26 pm

1 stop15h 05m

Key West

Wed 4/29

11:51 am-9:43 am

1 stop21h 52m

$203

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 4/20

12:10 pm-12:21 pm

2 stops24h 11m

Key West

Thu 4/23

9:46 am-8:16 pm

1 stop10h 30m

$214

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/19

7:00 pm-12:26 pm

2 stops17h 26m

Key West

Wed 4/22

11:51 am-9:43 am

1 stop21h 52m

$225
Quickest round-trip

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 5/5

12:49 pm-7:40 pm

1 stop6h 51m

Key West

Tue 5/12

6:19 pm-12:25 am

1 stop6h 06m

$247

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/26

7:00 pm-2:43 pm

2 stops19h 43m

Key West

Wed 4/29

11:51 am-9:43 am

1 stop21h 52m

$248

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sat 5/16

2:52 pm-10:36 pm

2 stops7h 44m

Key West

Wed 5/20

2:29 pm-11:39 pm

1 stop9h 10m

$252

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/19

8:39 am-10:24 am

1 stop25h 45m

Key West

Wed 4/22

11:51 am-9:43 am

1 stop21h 52m

$255

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sat 5/2

8:30 pm-9:06 am

1 stop12h 36m

Key West

Sat 5/9

11:54 am-5:10 pm

2 stops29h 16m

$257

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/19

8:39 am-10:24 am

1 stop25h 45m

Key West

Thu 4/23

11:01 am-5:40 pm

2 stops30h 39m

$264

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sat 5/2

8:30 pm-9:06 am

1 stop12h 36m

Key West

Fri 5/8

12:07 pm-7:53 pm

1 stop7h 46m

$266

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbus to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbus and Key West?

What is the cheapest month to fly to Key West?

In general, February is the cheapest month to fly from Columbus to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $305. If you are unable to visit Key West during the month of February, then departing from Columbus during the month September is also very affordable. Most momondo users find prices during this month for around $313.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Columbus when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $388 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Columbus for as low as $297 on momondo.

Cheap Columbus to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Key West

Fastest flight time

4h 24m

Direct flights

None
The fastest flight from Columbus to Key West takes 4h 24m
There are no direct flights from Columbus to Key West. There are no popular flight routes from Columbus to Key West.
Search flight deals

Frequently asked questions about flying from Columbus to Key West

  • How far is Columbus to Key West by plane?

    Columbus and Key West are 1066.3 mi apart from one another. Flights usually cover this in 4h 24m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbus to Key West Airport?

    Prices for flights from Columbus to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus to Key West Airport?

  • How old do you have to be to fly from Columbus to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Columbus to Key West

Compare and see reviews for airlines that fly from Columbus to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $135Free CancellationRating
6.3
8,601 reviews
Search Spirit Airlines flights
Allegiant AirPriceFrom $152Free CancellationRating
7.3
706 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $165Free CancellationRating
7.4
9,550 reviews
Search United Airlines flights
DeltaPriceFrom $250Free CancellationRating
7.9
8,387 reviews
Search Delta flights
American AirlinesPriceFrom $251Free CancellationRating
7.1
11,552 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Key West?

It is quick and easy to find Columbus to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbus to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Columbus on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbus to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Columbus.

I’m not ready to book a flight from Columbus to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

An easier way to manage your Key West trip

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