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Cheap flights from Columbus to Key West from $127

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to Key West departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:45 am - 9:06 am
CMH
-
EYW
21h 21m
1 stop
Multiple Airlines Logo
9:49 am - 11:42 am
EYW
-
CMH
25h 53m
2 stops
$245Multiple Airlines
Wed, Mar 18 - Mon, Mar 23
Delta Logo
1:09 pm - 5:30 pm
CMH
-
EYW
4h 21m
1 stop
Delta Logo
7:33 am - 1:54 pm
EYW
-
CMH
6h 21m
1 stop
$251Delta
Wed, Apr 8 - Wed, Apr 15
Multiple Airlines Logo
2:51 pm - 12:26 pm
CMH
-
EYW
21h 35m
2 stops
Multiple Airlines Logo
11:51 am - 11:53 pm
EYW
-
CMH
12h 02m
1 stop
$255Multiple Airlines
Sun, Mar 8 - Wed, Mar 11
American Airlines Logo
2:36 pm - 10:18 pm
CMH
-
EYW
7h 42m
2 stops
American Airlines Logo
7:42 pm - 12:59 am
EYW
-
CMH
5h 17m
1 stop
$256American Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
7:00 pm - 9:09 am
CMH
-
EYW
14h 09m
2 stops
Multiple Airlines Logo
11:51 am - 9:43 am
EYW
-
CMH
21h 52m
1 stop
$259Multiple Airlines
Thu, Apr 16 - Wed, Apr 22
Delta Logo
3:00 pm - 7:40 pm
CMH
-
EYW
4h 40m
1 stop
Delta Logo
2:40 pm - 8:32 pm
EYW
-
CMH
5h 52m
1 stop
$265Delta
Mon, Apr 20 - Wed, Apr 29
Multiple Airlines Logo
12:10 pm - 12:21 pm
CMH
-
EYW
24h 11m
2 stops
Multiple Airlines Logo
11:51 am - 9:43 am
EYW
-
CMH
21h 52m
1 stop
$266Multiple Airlines
Mon, Apr 20 - Wed, Apr 29
American Airlines Logo
8:00 am - 4:30 pm
CMH
-
EYW
8h 30m
2 stops
American Airlines Logo
2:29 pm - 11:31 pm
EYW
-
CMH
9h 02m
1 stop
$270American Airlines
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
6:05 am - 12:26 pm
CMH
-
EYW
6h 21m
1 stop
Multiple Airlines Logo
9:49 am - 11:42 am
EYW
-
CMH
25h 53m
2 stops
$275Multiple Airlines
Mon, Mar 23 - Mon, Mar 30
Multiple Airlines Logo
6:05 am - 9:06 am
CMH
-
EYW
27h 01m
1 stop
Multiple Airlines Logo
11:51 am - 2:52 pm
EYW
-
CMH
27h 01m
2 stops
$276Multiple Airlines
Wed, Apr 8 - Wed, Apr 15

Delta flights from Columbus to Key West

Our best Delta deals on Columbus to Key West flight tickets
Delta
Apr 8
CMH1:09 pmColumbus
4h 21m
1 stop
EYW5:30 pmKey West
Apr 15
EYW7:33 amKey West
6h 21m
1 stop
CMH1:54 pmColumbus
$251
Delta
Apr 20
CMH3:00 pmColumbus
4h 40m
1 stop
EYW7:40 pmKey West
Apr 29
EYW2:40 pmKey West
5h 52m
1 stop
CMH8:32 pmColumbus
$265
Delta
Mar 31
CMH11:10 amColumbus
6h 20m
1 stop
EYW5:30 pmKey West
Apr 14
EYW7:33 amKey West
6h 21m
1 stop
CMH1:54 pmColumbus
$280

American Airlines flights from Columbus to Key West

Our best American Airlines deals on Columbus to Key West flight tickets
American Airlines
Mar 17
CMH2:36 pmColumbus
7h 42m
2 stops
EYW10:18 pmKey West
Mar 24
EYW7:42 pmKey West
5h 17m
1 stop
CMH12:59 amColumbus
$256
American Airlines
Apr 14
CMH8:00 amColumbus
8h 30m
2 stops
EYW4:30 pmKey West
Apr 21
EYW2:29 pmKey West
9h 02m
1 stop
CMH11:31 pmColumbus
$270
American Airlines
Apr 22
CMH6:00 amColumbus
7h 42m
1 stop
EYW1:42 pmKey West
Apr 28
EYW2:29 pmKey West
9h 02m
1 stop
CMH11:31 pmColumbus
$279

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from Columbus to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 3/18

11:45 am-9:06 am

1 stop21h 21m

Key West

Mon 3/23

9:49 am-11:42 am

2 stops25h 53m

$245

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 4/8

1:09 pm-5:30 pm

1 stop4h 21m

Key West

Wed 4/15

7:33 am-1:54 pm

1 stop6h 21m

$251

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 3/8

2:51 pm-12:26 pm

2 stops21h 35m

Key West

Wed 3/11

11:51 am-11:53 pm

1 stop12h 02m

$255

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 3/17

2:36 pm-10:18 pm

2 stops7h 42m

Key West

Tue 3/24

7:42 pm-12:59 am

1 stop5h 17m

$256

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Thu 4/16

7:00 pm-9:09 am

2 stops14h 09m

Key West

Wed 4/22

11:51 am-9:43 am

1 stop21h 52m

$259

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 4/20

3:00 pm-7:40 pm

1 stop4h 40m

Key West

Wed 4/29

2:40 pm-8:32 pm

1 stop5h 52m

$265

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 4/20

12:10 pm-12:21 pm

2 stops24h 11m

Key West

Wed 4/29

11:51 am-9:43 am

1 stop21h 52m

$266

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 4/14

8:00 am-4:30 pm

2 stops8h 30m

Key West

Tue 4/21

2:29 pm-11:31 pm

1 stop9h 02m

$270

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 3/23

6:05 am-12:26 pm

1 stop6h 21m

Key West

Mon 3/30

9:49 am-11:42 am

2 stops25h 53m

$275

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 4/8

6:05 am-9:06 am

1 stop27h 01m

Key West

Wed 4/15

11:51 am-2:52 pm

2 stops27h 01m

$276

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbus to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Columbus to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $309. If you are unable to visit Key West during the month of September, then departing from Columbus during the month February is also very affordable. Most momondo users find prices during this month for around $319.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Columbus when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $382 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Columbus for as low as $268 on momondo.

Cheap Columbus to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Key West

Fastest flight time

4h 21m

Direct flights

None
The fastest flight from Columbus to Key West takes 4h 21m
There are no direct flights from Columbus to Key West. There are no popular flight routes from Columbus to Key West.
Search flight deals

  • How far is Columbus to Key West by plane?

    Columbus and Key West are 1066.3 mi apart from one another. Flights usually cover this in 4h 21m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbus to Key West Airport?

    Prices for flights from Columbus to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus to Key West Airport?

  • How old do you have to be to fly from Columbus to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Columbus to Key West

Compare and see reviews for airlines that fly from Columbus to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $96Free CancellationRating
6.3
8,494 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $165Free CancellationRating
7.4
9,348 reviews
Search United Airlines flights
DeltaPriceFrom $250Free CancellationRating
7.9
8,237 reviews
Search Delta flights
American AirlinesPriceFrom $251Free CancellationRating
7.2
11,352 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Key West?

It is quick and easy to find Columbus to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbus to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Columbus on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbus to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Columbus.

I’m not ready to book a flight from Columbus to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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