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Cheap flights from Columbus to Key West from $107

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to Key West departing on 4/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Columbus to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:42 am - 1:37 pm
CMH
-
EYW
25h 55m
1 stop
Multiple Airlines Logo
4:22 pm - 5:40 pm
EYW
-
CMH
25h 18m
2 stops
$235Multiple Airlines
Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
11:42 am - 1:37 pm
CMH
-
EYW
25h 55m
1 stop
Multiple Airlines Logo
9:46 am - 10:08 am
EYW
-
CMH
24h 22m
1 stop
$260Multiple Airlines
Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
6:05 am - 9:06 am
CMH
-
EYW
27h 01m
1 stop
Multiple Airlines Logo
12:39 pm - 2:52 pm
EYW
-
CMH
26h 13m
2 stops
$262Multiple Airlines
Wed, Apr 8 - Wed, Apr 15
Multiple Airlines Logo
6:40 pm - 12:31 pm
CMH
-
EYW
17h 51m
2 stops
Multiple Airlines Logo
12:10 pm - 8:16 pm
EYW
-
CMH
8h 06m
1 stop
$264Multiple Airlines
Sun, May 10 - Fri, May 15
Multiple Airlines Logo
6:05 am - 9:06 am
CMH
-
EYW
27h 01m
1 stop
Multiple Airlines Logo
11:51 am - 2:52 pm
EYW
-
CMH
27h 01m
2 stops
$269Multiple Airlines
Wed, Apr 8 - Wed, Apr 15
Multiple Airlines Logo
11:45 am - 9:06 am
CMH
-
EYW
21h 21m
1 stop
Multiple Airlines Logo
9:49 am - 11:42 am
EYW
-
CMH
25h 53m
2 stops
$273Multiple Airlines
Wed, Mar 25 - Mon, Mar 30
Multiple Airlines Logo
8:30 pm - 9:06 am
CMH
-
EYW
12h 36m
1 stop
Multiple Airlines Logo
12:05 pm - 2:41 pm
EYW
-
CMH
26h 36m
2 stops
$274Multiple Airlines
Sat, May 2 - Thu, May 7
Multiple Airlines Logo
3:36 pm - 12:34 pm
CMH
-
EYW
20h 58m
2 stops
Multiple Airlines Logo
12:10 pm - 7:53 pm
EYW
-
CMH
7h 43m
1 stop
$275Multiple Airlines
Mon, May 11 - Fri, May 15
Multiple Airlines Logo
4:15 pm - 11:11 am
CMH
-
EYW
18h 56m
1 stop
Multiple Airlines Logo
9:49 am - 9:44 am
EYW
-
CMH
23h 55m
2 stops
$276Multiple Airlines
Tue, Mar 24 - Fri, Mar 27
Multiple Airlines Logo
6:05 pm - 12:34 pm
CMH
-
EYW
42h 29m
2 stops
Multiple Airlines Logo
12:10 pm - 5:44 pm
EYW
-
CMH
5h 34m
1 stop
$280Multiple Airlines
Sun, May 10 - Fri, May 15

Delta flights from Columbus to Key West

Our best Delta deals on Columbus to Key West flight tickets
Delta
Apr 8
CMH1:09 pmColumbus
4h 21m
1 stop
EYW5:30 pmKey West
Apr 15
EYW6:23 pmKey West
6h 20m
1 stop
CMH12:43 amColumbus
$285
Delta
Mar 31
CMH1:00 pmColumbus
6h 41m
1 stop
EYW7:41 pmKey West
Apr 14
EYW7:33 amKey West
6h 21m
1 stop
CMH1:54 pmColumbus
$299
Delta
May 19
CMH12:55 pmColumbus
6h 54m
1 stop
EYW7:49 pmKey West
May 27
EYW6:19 pmKey West
6h 06m
1 stop
CMH12:25 amColumbus
$315

American Airlines flights from Columbus to Key West

Our best American Airlines deals on Columbus to Key West flight tickets
American Airlines
Apr 8
CMH2:52 pmColumbus
7h 44m
2 stops
EYW10:36 pmKey West
Apr 15
EYW6:45 amKey West
7h 27m
2 stops
CMH2:12 pmColumbus
$309
American Airlines
May 29
CMH11:10 amColumbus
7h 39m
1 stop
EYW6:49 pmKey West
Jun 4
EYW5:37 pmKey West
6h 10m
1 stop
CMH11:47 pmColumbus
$314
American Airlines
Mar 31
CMH2:42 pmColumbus
7h 36m
2 stops
EYW10:18 pmKey West
Apr 14
EYW2:29 pmKey West
9h 02m
1 stop
CMH11:31 pmColumbus
$319

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Columbus to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/12

11:42 am-1:37 pm

1 stop25h 55m

Key West

Thu 4/16

4:22 pm-5:40 pm

2 stops25h 18m

$235

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/12

11:42 am-1:37 pm

1 stop25h 55m

Key West

Thu 4/16

9:46 am-10:08 am

1 stop24h 22m

$260

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 4/8

6:05 am-9:06 am

1 stop27h 01m

Key West

Wed 4/15

12:39 pm-2:52 pm

2 stops26h 13m

$262
Quickest round-trip

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 5/10

6:40 pm-12:31 pm

2 stops17h 51m

Key West

Fri 5/15

12:10 pm-8:16 pm

1 stop8h 06m

$264

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 4/8

6:05 am-9:06 am

1 stop27h 01m

Key West

Wed 4/15

11:51 am-2:52 pm

2 stops27h 01m

$269

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Wed 3/25

11:45 am-9:06 am

1 stop21h 21m

Key West

Mon 3/30

9:49 am-11:42 am

2 stops25h 53m

$273

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sat 5/2

8:30 pm-9:06 am

1 stop12h 36m

Key West

Thu 5/7

12:05 pm-2:41 pm

2 stops26h 36m

$274

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Mon 5/11

3:36 pm-12:34 pm

2 stops20h 58m

Key West

Fri 5/15

12:10 pm-7:53 pm

1 stop7h 43m

$275

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 3/24

4:15 pm-11:11 am

1 stop18h 56m

Key West

Fri 3/27

9:49 am-9:44 am

2 stops23h 55m

$276

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 5/10

6:05 pm-12:34 pm

2 stops42h 29m

Key West

Fri 5/15

12:10 pm-5:44 pm

1 stop5h 34m

$280

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbus to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, February is the cheapest month to fly from Columbus to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $305. If you are unable to visit Key West during the month of February, then departing from Columbus during the month September is also very affordable. Most momondo users find prices during this month for around $311.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Columbus when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $378 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Columbus for as low as $268 on momondo.

Cheap Columbus to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Key West

Fastest flight time

4h 53m

Direct flights

None
The fastest flight from Columbus to Key West takes 4h 53m
There are no direct flights from Columbus to Key West. There are no popular flight routes from Columbus to Key West.
Search flight deals

  • How far is Columbus to Key West by plane?

    Columbus and Key West are 1066.3 mi apart from one another. Flights usually cover this in 4h 53m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbus to Key West Airport?

    Prices for flights from Columbus to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus to Key West Airport?

  • How old do you have to be to fly from Columbus to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Columbus to Key West

Compare and see reviews for airlines that fly from Columbus to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $116Free CancellationRating
6.3
8,518 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $165Free CancellationRating
7.4
9,418 reviews
Search United Airlines flights
DeltaPriceFrom $243Free CancellationRating
7.9
8,286 reviews
Search Delta flights
American AirlinesPriceFrom $250Free CancellationRating
7.1
11,432 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Key West?

It is quick and easy to find Columbus to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbus to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Columbus on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbus to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Columbus.

I’m not ready to book a flight from Columbus to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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