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Cheap flights from Columbus to Key West from $128

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to Key West departing on 4/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:40 pm - 12:26 pm
CMH
-
EYW
17h 46m
1 stop
Multiple Airlines Logo
11:01 am - 5:40 pm
EYW
-
CMH
30h 39m
2 stops
$217Multiple Airlines
Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
6:40 pm - 12:26 pm
CMH
-
EYW
17h 46m
1 stop
Multiple Airlines Logo
9:46 am - 10:08 am
EYW
-
CMH
24h 22m
1 stop
$243Multiple Airlines
Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
6:05 am - 3:00 pm
CMH
-
EYW
8h 55m
1 stop
Multiple Airlines Logo
2:04 pm - 5:40 pm
EYW
-
CMH
27h 36m
2 stops
$247Multiple Airlines
Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
6:40 pm - 12:26 pm
CMH
-
EYW
17h 46m
1 stop
Multiple Airlines Logo
11:01 am - 5:40 pm
EYW
-
CMH
30h 39m
2 stops
$278Multiple Airlines
Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
6:05 am - 3:00 pm
CMH
-
EYW
8h 55m
1 stop
Multiple Airlines Logo
2:04 pm - 10:08 am
EYW
-
CMH
20h 04m
1 stop
$284Multiple Airlines
Sun, Apr 12 - Thu, Apr 16
Delta Logo
12:49 pm - 5:23 pm
CMH
-
EYW
4h 34m
1 stop
Delta Logo
1:22 pm - 5:49 pm
EYW
-
CMH
4h 27m
1 stop
$291Delta
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
7:00 pm - 9:09 am
CMH
-
EYW
14h 09m
2 stops
Multiple Airlines Logo
1:06 pm - 8:16 pm
EYW
-
CMH
7h 10m
1 stop
$295Multiple Airlines
Sun, Apr 19 - Mon, Apr 27
American Airlines Logo
6:15 pm - 10:58 pm
CMH
-
EYW
4h 43m
1 stop
American Airlines Logo
3:58 pm - 12:21 am
EYW
-
CMH
8h 23m
2 stops
$296American Airlines
Sat, May 2 - Sat, May 9
American Airlines Logo
2:57 pm - 10:36 pm
CMH
-
EYW
7h 39m
2 stops
American Airlines Logo
3:58 pm - 12:21 am
EYW
-
CMH
8h 23m
2 stops
$301American Airlines
Sat, May 2 - Sat, May 9
Multiple Airlines Logo
7:00 pm - 9:09 am
CMH
-
EYW
14h 09m
2 stops
Multiple Airlines Logo
1:06 pm - 8:16 pm
EYW
-
CMH
7h 10m
1 stop
$308Multiple Airlines
Sun, Apr 19 - Mon, Apr 27

Delta flights from Columbus to Key West

Our best Delta deals on Columbus to Key West flight tickets
Delta
May 5
CMH12:49 pmColumbus
4h 34m
1 stop
EYW5:23 pmKey West
May 12
EYW1:22 pmKey West
4h 27m
1 stop
CMH5:49 pmColumbus
$291
Delta
May 6
CMH3:00 pmColumbus
4h 40m
1 stop
EYW7:40 pmKey West
May 10
EYW6:19 pmKey West
6h 11m
1 stop
CMH12:30 amColumbus
$315
Delta
May 7
CMH3:02 pmColumbus
4h 47m
1 stop
EYW7:49 pmKey West
May 9
EYW6:19 pmKey West
6h 06m
1 stop
CMH12:25 amColumbus
$369

American Airlines flights from Columbus to Key West

Our best American Airlines deals on Columbus to Key West flight tickets
American Airlines
May 2
CMH6:15 pmColumbus
4h 43m
1 stop
EYW10:58 pmKey West
May 9
EYW3:58 pmKey West
8h 23m
2 stops
CMH12:21 amColumbus
$296
American Airlines
May 2
CMH2:57 pmColumbus
7h 39m
2 stops
EYW10:36 pmKey West
May 9
EYW3:58 pmKey West
8h 23m
2 stops
CMH12:21 amColumbus
$301
American Airlines
May 2
CMH6:15 pmColumbus
4h 43m
1 stop
EYW10:58 pmKey West
May 9
EYW3:58 pmKey West
8h 23m
2 stops
CMH12:21 amColumbus
$320

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Columbus to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/12

6:40 pm-12:26 pm

1 stop17h 46m

Key West

Thu 4/16

11:01 am-5:40 pm

2 stops30h 39m

$217

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/12

6:40 pm-12:26 pm

1 stop17h 46m

Key West

Thu 4/16

9:46 am-10:08 am

1 stop24h 22m

$243

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/12

6:05 am-3:00 pm

1 stop8h 55m

Key West

Thu 4/16

2:04 pm-5:40 pm

2 stops27h 36m

$247

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/12

6:40 pm-12:26 pm

1 stop17h 46m

Key West

Thu 4/16

11:01 am-5:40 pm

2 stops30h 39m

$278

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/12

6:05 am-3:00 pm

1 stop8h 55m

Key West

Thu 4/16

2:04 pm-10:08 am

1 stop20h 04m

$284
Quickest round-trip

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Tue 5/5

12:49 pm-5:23 pm

1 stop4h 34m

Key West

Tue 5/12

1:22 pm-5:49 pm

1 stop4h 27m

$291

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/19

7:00 pm-9:09 am

2 stops14h 09m

Key West

Mon 4/27

1:06 pm-8:16 pm

1 stop7h 10m

$295

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sat 5/2

6:15 pm-10:58 pm

1 stop4h 43m

Key West

Sat 5/9

3:58 pm-12:21 am

2 stops8h 23m

$296

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sat 5/2

2:57 pm-10:36 pm

2 stops7h 39m

Key West

Sat 5/9

3:58 pm-12:21 am

2 stops8h 23m

$301

ColumbusKey West

CMH - EYW

CMHEYW

Columbus

Sun 4/19

7:00 pm-9:09 am

2 stops14h 09m

Key West

Mon 4/27

1:06 pm-8:16 pm

1 stop7h 10m

$308

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbus to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbus and Key West?

What is the cheapest month to fly to Key West?

In general, February is the cheapest month to fly from Columbus to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $305. If you are unable to visit Key West during the month of February, then departing from Columbus during the month September is also very affordable. Most momondo users find prices during this month for around $311.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Columbus when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $378 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Columbus for as low as $268 on momondo.

Cheap Columbus to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Key West

Fastest flight time

4h 35m

Direct flights

None
The fastest flight from Columbus to Key West takes 4h 35m
There are no direct flights from Columbus to Key West. There are no popular flight routes from Columbus to Key West.
Search flight deals

  • How far is Columbus to Key West by plane?

    Columbus and Key West are 1066.3 mi apart from one another. Flights usually cover this in 4h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbus to Key West Airport?

    Prices for flights from Columbus to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbus to Key West Airport?

  • How old do you have to be to fly from Columbus to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbus to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Columbus to Key West

Compare and see reviews for airlines that fly from Columbus to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $135Free CancellationRating
6.3
8,546 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $145Free CancellationRating
7.4
9,486 reviews
Search United Airlines flights
DeltaPriceFrom $250Free CancellationRating
7.9
8,333 reviews
Search Delta flights
American AirlinesPriceFrom $250Free CancellationRating
7.1
11,496 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Key West?

It is quick and easy to find Columbus to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbus to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Columbus on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Columbus to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Columbus.

I’m not ready to book a flight from Columbus to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Columbus to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

An easier way to manage your Key West trip

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