What airlines fly to Knoxville?

American Airlines, United Airlines and Allegiant Air are the top three most popular airlines that fly to Knoxville from Colorado according to our data. American Airlines is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Colorado to Knoxville McGhee Tyson?

Frontier, Allegiant Air, and Delta are the most popular carriers operating from Colorado to Knoxville McGhee Tyson

How many flights depart from Colorado to Knoxville on average per week?

As of November 2025, 14 flights take off from Colorado and land in Knoxville each week. The most common flight departure day for this route is Thu, with 29% of weekly flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Colorado to Knoxville depends on which airport you fly into and out of. Flying from Denver to Knoxville is 2h 38m on average, while flying from Aspen to Knoxville is 4h 53m on average. Knoxville is the most popular airport in Knoxville.

How many flights depart from Colorado to Knoxville on average per day?

As of November 2025, there are 2 flights per day flying from Colorado to Knoxville. The most common time of day flights depart is 5:00PM, with 53% of flights taking off in the afternoon.

When did momondo last update prices for flights from Colorado to Knoxville McGhee Tyson Airport?

Prices for flights from Colorado to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Colorado to Knoxville McGhee Tyson Airport?

As of November 2025, there are 5 operators available to choose from for flights from Colorado to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Colorado to Knoxville McGhee Tyson Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Colorado to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$48 Cheap Flights from Colorado to Knoxville in 2025/26

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8:33 am - 1:11 pmDEN-TYS

2h 38mnonstop

6:30 am - 7:43 amTYS-DEN

3h 13mnonstop

$92Allegiant Air

Find Deal

Thu, Dec 4 - Sun, Dec 7

10:46 am - 3:31 pmDEN-TYS

2h 45mnonstop

4:26 pm - 5:57 pmTYS-DEN

3h 31mnonstop

$98Frontier

Find Deal

Thu, Dec 25 - Sun, Jan 4

8:33 am - 1:11 pmDEN-TYS

2h 38mnonstop

6:30 am - 7:43 amTYS-DEN

3h 13mnonstop

$99Allegiant Air

Find Deal

Thu, Dec 4 - Thu, Dec 11

8:33 am - 1:11 pmDEN-TYS

2h 38mnonstop

4:52 pm - 6:23 pmTYS-DEN

3h 31mnonstop

$106Multiple Airlines

Find Deal

Thu, Dec 4 - Thu, Dec 11

11:07 am - 3:53 pmDEN-TYS

2h 46mnonstop

6:30 am - 7:43 amTYS-DEN

3h 13mnonstop

$116Multiple Airlines

Find Deal

Fri, Nov 28 - Thu, Dec 4

12:36 pm - 9:40 pmCOS-TYS

7h 04m1 stop

4:22 pm - 8:30 pmTYS-COS

6h 08m1 stop

$249American Airlines

Find Deal

Wed, Dec 3 - Wed, Dec 10

12:45 pm - 10:55 pmCOS-TYS

8h 10m2 stops

4:22 pm - 8:30 pmTYS-COS

6h 08m1 stop

$321American Airlines

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Wed, Dec 3 - Wed, Dec 10

6:00 pm - 9:38 amCOS-TYS

13h 38m2 stops

7:39 am - 5:19 pmTYS-COS

11h 40m2 stops

$377Delta

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Wed, Dec 3 - Wed, Dec 10

11:35 am - 11:59 pmCOS-TYS

10h 24m2 stops

7:00 am - 11:18 amTYS-COS

6h 18m1 stop

$379United Airlines

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Wed, Apr 15 - Sat, Apr 18

12:30 pm - 10:55 pmCOS-TYS

8h 25m1 stop

4:55 pm - 8:05 pmTYS-COS

5h 10m1 stop

$427United Airlines

Find Deal

Sat, Nov 22 - Wed, Nov 26

United Airlines flights from Colorado to Knoxville

Our best United Airlines deals on Colorado to Knoxville flight tickets

United Airlines

Apr 15

COS11:35 amColorado Springs

10h 24m

2 stops

TYS11:59 pmKnoxville McGhee Tyson

Apr 18

TYS7:00 amKnoxville McGhee Tyson

6h 18m

1 stop

COS11:18 amColorado Springs

$379

Find similar

United Airlines

Nov 19

COS7:30 amColorado Springs

8h 34m

1 stop

TYS6:04 pmKnoxville McGhee Tyson

Nov 23

TYS4:25 pmKnoxville McGhee Tyson

9h 34m

2 stops

COS11:59 pmColorado Springs

$384

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United Airlines

Nov 19

COS6:00 amColorado Springs

10h 04m

2 stops

TYS6:04 pmKnoxville McGhee Tyson

Nov 23

TYS4:25 pmKnoxville McGhee Tyson

9h 34m

2 stops

COS11:59 pmColorado Springs

$389

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American Airlines flights from Colorado to Knoxville

Our best American Airlines deals on Colorado to Knoxville flight tickets

American Airlines

Dec 3

COS12:36 pmColorado Springs

7h 04m

1 stop

TYS9:40 pmKnoxville McGhee Tyson

Dec 10

TYS4:22 pmKnoxville McGhee Tyson

6h 08m

1 stop

COS8:30 pmColorado Springs

$249

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American Airlines

Nov 19

COS5:17 pmColorado Springs

4h 51m

1 stop

TYS12:08 amKnoxville McGhee Tyson

Nov 23

TYS6:18 pmKnoxville McGhee Tyson

7h 30m

1 stop

COS11:48 pmColorado Springs

$299

Find similar

American Airlines

Dec 3

COS12:45 pmColorado Springs

8h 10m

2 stops

TYS10:55 pmKnoxville McGhee Tyson

Dec 10

TYS4:22 pmKnoxville McGhee Tyson

6h 08m

1 stop

COS8:30 pmColorado Springs

$321

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Fly from

Fly to

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/4

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Sun 12/7

6:30 am-7:43 am

Nonstop3h 13m

$92

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/25

10:46 am-3:31 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Sun 1/4

4:26 pm-5:57 pm

Nonstop3h 31m

$98

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/4

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Thu 12/11

6:30 am-7:43 am

Nonstop3h 13m

$99

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/4

8:33 am-1:11 pm

Nonstop2h 38m

Knoxville McGhee Tyson

Thu 12/11

4:52 pm-6:23 pm

Nonstop3h 31m

$106

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 11/28

11:07 am-3:53 pm

Nonstop2h 46m

Knoxville McGhee Tyson

Thu 12/4

6:30 am-7:43 am

Nonstop3h 13m

$116

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Wed 12/3

12:36 pm-9:40 pm

1 stop7h 04m

Knoxville McGhee Tyson

Wed 12/10

4:22 pm-8:30 pm

1 stop6h 08m

$249

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Wed 12/3

12:45 pm-10:55 pm

2 stops8h 10m

Knoxville McGhee Tyson

Wed 12/10

4:22 pm-8:30 pm

1 stop6h 08m

$321

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Wed 12/3

6:00 pm-9:38 am

2 stops13h 38m

Knoxville McGhee Tyson

Wed 12/10

7:39 am-5:19 pm

2 stops11h 40m

$377

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Wed 4/15

11:35 am-11:59 pm

2 stops10h 24m

Knoxville McGhee Tyson

Sat 4/18

7:00 am-11:18 am

1 stop6h 18m

$379

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Sat 11/22

12:30 pm-10:55 pm

1 stop8h 25m

Knoxville McGhee Tyson

Wed 11/26

4:55 pm-8:05 pm

1 stop5h 10m

$427

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Colorado to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

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Other information

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Colorado, with most prices found around $179. If you aren’t able to travel during the month of August, then book flights to Knoxville from Colorado during April instead. Flights to Knoxville in April, while not as cheap as those in August, still average around $192.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Colorado to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $169. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Colorado to Knoxville for around $377.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Colorado to Knoxville when you can find flight prices for as low as $164. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $244.

What is the cheapest Colorado to Knoxville McGhee Tyson flight route?

Fly from Denver Intl to Knoxville McGhee Tyson for the best Colorado - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Colorado when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $256 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Colorado for as low as $176 on momondo.

What cabin class options are available on Colorado to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Colorado to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Colorado to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Colorado to Knoxville.

Cheap Colorado to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Colorado to Knoxville

Best Price Found	$124
Fastest flight time	2h 38m
Direct flights	Every day
Airports in Knoxville	1 airport

The best one-way flight to Knoxville from Colorado in the past 72 hours is $124. The best round-trip flight deal from Colorado to Knoxville found on momondo in the last 72 hours is $187.

The fastest flight from Colorado to Knoxville takes 2h 38m

Direct flights go from Colorado to Knoxville every day.

There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

Search flight deals

When did momondo last update prices for flights from Colorado to Knoxville McGhee Tyson Airport?
Prices for flights from Colorado to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Colorado to Knoxville McGhee Tyson Airport?
As of November 2025, there are 5 operators available to choose from for flights from Colorado to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Colorado to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Colorado to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Colorado to Knoxville?
Based on momondo bookings for flights between Colorado and Knoxville, the leading plane model is Embraer 175 (Enhanced Winglets), making up 30.84% of the total bookings. Other popular models include Boeing 737 MAX 8 with 19.69%, Airbus A320-100/200 with 18.03%, and Airbus A320neo with 14.47%.

Best airlines flying from Colorado to Knoxville

Compare and see reviews for airlines that fly from Colorado to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $64	Free Cancellation	Rating 7.2 697 reviews	Search Allegiant Air flights
Frontier	PriceFrom $81	Free Cancellation	Rating 5.8 3,116 reviews	Search Frontier flights
Delta	PriceFrom $133	Free Cancellation	Rating 7.9 8,001 reviews	Search Delta flights
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.2 11,040 reviews	Search American Airlines flights
United Airlines	PriceFrom $233	Free Cancellation	Rating 7.4 9,007 reviews	Search United Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Maryville

Murphy

Alcoa

Oak Ridge

Newport

Lenoir City

Kodak

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Colorado to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Colorado to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Colorado to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Colorado to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Colorado to Knoxville?

momondo helps you find the best flight between Colorado and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Colorado to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Colorado. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Colorado to Knoxville from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Colorado to Knoxville departing on 11/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Colorado to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

What is the cheapest time of day to depart on your flight to Knoxville?

What is the cheapest Colorado to Knoxville McGhee Tyson flight route?

Fly from Denver Intl to Knoxville McGhee Tyson for the best Colorado - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

What cabin class options are available on Colorado to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Colorado to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Colorado to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Colorado to Knoxville.

What is the cheapest airline that flies from Colorado to Knoxville McGhee Tyson?

Frontier, Allegiant Air, and Delta are the most popular carriers operating from Colorado to Knoxville McGhee Tyson

What airlines fly to Knoxville?

How many flights depart from Colorado to Knoxville on average per day?

As of November 2025, there are 2 flights per day flying from Colorado to Knoxville. The most common time of day flights depart is 5:00PM, with 53% of flights taking off in the afternoon.

How many flights depart from Colorado to Knoxville on average per week?

As of November 2025, 14 flights take off from Colorado and land in Knoxville each week. The most common flight departure day for this route is Thu, with 29% of weekly flights taking off on this day.

How long does it take to fly to Knoxville?

Average flight duration from Colorado to Knoxville depends on which airport you fly into and out of. Flying from Denver to Knoxville is 2h 38m on average, while flying from Aspen to Knoxville is 4h 53m on average. Knoxville is the most popular airport in Knoxville.

Cheap Colorado to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Colorado to Knoxville

Best Price Found

Fastest flight time

Direct flights

Airports in Knoxville

When did momondo last update prices for flights from Colorado to Knoxville McGhee Tyson Airport?

How many operators does momondo search for flights from Colorado to Knoxville McGhee Tyson Airport?

How old do you have to be to fly from Colorado to Knoxville McGhee Tyson Airport?

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

What is the most popular plane model from Colorado to Knoxville?

Best airlines flying from Colorado to Knoxville

Compare and see reviews for airlines that fly from Colorado to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Colorado to Knoxville?

Can I find flights from Colorado to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Colorado to Knoxville?

I’m not ready to book a flight from Colorado to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Tennessee