Cheap flights from Cleveland to Missouri from $59

In general, October is the cheapest month to fly from Cleveland to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $295. If you aren’t able to travel to Missouri during the month of October, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $341.

The cheapest day to depart from Cleveland to Missouri is on a Wednesday when prices can be found for as low as $389. Flights from Cleveland to Missouri on a Monday will generally be more expensive and average around $465. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Missouri is in the afternoon. momondo users have found flights departing from Cleveland to Missouri in the afternoon for as low as $361. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $423. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Cleveland Hopkins Intl to Lambert-St Louis for the best Cleveland Hopkins Intl - Missouri flight prices

You are more likely to see cheaper flights to Missouri from Cleveland when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $352 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Cleveland for as low as $236 on momondo.

There is only 1 cabin class available to choose from on Cleveland to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, Delta, and Frontier are the most popular carriers operating from Cleveland Hopkins Intl to Missouri

Southwest, Delta and United Airlines are the top three most popular airlines that fly to Missouri from Cleveland according to our data. Southwest is the first choice among our users, with 36% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 5 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

As of August 2026, 1 flights take off from Cleveland and land in Missouri each day. The most common flight departure time for this route is 7:00AM, with 69% of daily flights taking off at noon.

As of August 2026, 11 flights take off from Cleveland and land in Missouri each week. The most common flight departure day for this route is Tue, with 27% of weekly flights taking off on this day.