What airlines fly to Greenville?

American Airlines, Delta and Frontier are the top three most popular airlines that fly to Greenville from Cleveland according to our data. American Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 6 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Cleveland Hopkins Intl to Greenville?

Delta is the most popular carrier operating from Cleveland Hopkins Intl to Greenville

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Greenville Airport?

Prices for flights from Cleveland Hopkins Intl Airport to Greenville Airport refresh daily.

How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Greenville Airport?

There are 4 operators available for flights from Cleveland Hopkins Intl Airport to Greenville Airport as of September 2026.

How old do you have to be to fly from Cleveland Hopkins Intl Airport to Greenville Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$120 Cheap Flights from Cleveland to Greenville in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Cleveland to Greenville

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:45 pm - 7:44 pmCLE Cleveland Hopkins Intl-GSP Greenville

27h 59m2 stops Atlanta Hartsfield-Jackson Tampa

8:32 pm - 8:57 amGSP Greenville-CLE Cleveland Hopkins Intl

12h 25m1 stop Orlando

$221Multiple Airlines

Tue, Oct 6 - Mon, Oct 12

9:59 pm - 1:40 pmCLE Cleveland Hopkins Intl-GSP Greenville

15h 41m1 stop Orlando

8:32 pm - 8:57 amGSP Greenville-CLE Cleveland Hopkins Intl

12h 25m1 stop Orlando

$234Multiple Airlines

Fri, Oct 9 - Mon, Oct 12

6:10 am - 10:20 amCLE Cleveland Hopkins Intl-GSP Greenville

4h 10m1 stop Detroit Metropolitan Wayne County

5:40 am - 12:03 pmGSP Greenville-CLE Cleveland Hopkins Intl

6h 23m1 stop Atlanta Hartsfield-Jackson

$279Delta

Wed, Oct 14 - Tue, Oct 20

7:05 am - 1:00 pmCLE Cleveland Hopkins Intl-GSP Greenville

5h 55m1 stop Atlanta Hartsfield-Jackson

6:57 pm - 11:46 pmGSP Greenville-CLE Cleveland Hopkins Intl

4h 49m1 stop Detroit Metropolitan Wayne County

$279Delta

Wed, Oct 7 - Tue, Oct 13

10:23 am - 6:08 pmCLE Cleveland Hopkins Intl-GSP Greenville

7h 45m1 stop Chicago O'Hare Intl

4:37 pm - 11:53 pmGSP Greenville-CLE Cleveland Hopkins Intl

7h 16m1 stop Chicago O'Hare Intl

$279American Airlines

Mon, Oct 26 - Mon, Nov 2

12:51 pm - 6:08 pmCLE Cleveland Hopkins Intl-GSP Greenville

5h 17m1 stop Chicago O'Hare Intl

6:01 am - 12:16 pmGSP Greenville-CLE Cleveland Hopkins Intl

6h 15m1 stop Chicago O'Hare Intl

$279American Airlines

Sat, Oct 24 - Sat, Oct 31

4:20 pm - 8:05 pmCLE Cleveland Hopkins Intl-GSP Greenville

3h 45m1 stop Baltimore/Washington

7:00 am - 12:55 pmGSP Greenville-CLE Cleveland Hopkins Intl

5h 55m1 stop Nashville Intl

$279Southwest

Wed, Oct 14 - Tue, Oct 20

6:15 am - 12:40 pmCLE Cleveland Hopkins Intl-GSP Greenville

6h 25m1 stop Nashville Intl

6:40 am - 12:55 pmGSP Greenville-CLE Cleveland Hopkins Intl

6h 15m2 stops Nashville Intl Lambert-St Louis

$284Southwest

Wed, Oct 21 - Sat, Oct 24

7:00 am - 7:00 pmCLE Cleveland Hopkins Intl-GSP Greenville

12h 00m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

7:35 pm - 11:59 pmGSP Greenville-CLE Cleveland Hopkins Intl

4h 24m1 stop Washington, D.C. Dulles Intl

$457United Airlines

Sat, Oct 3 - Mon, Oct 5

4:23 pm - 9:17 pmCLE Cleveland Hopkins Intl-GSP Greenville

4h 54m1 stop Chicago O'Hare Intl

7:35 pm - 11:59 pmGSP Greenville-CLE Cleveland Hopkins Intl

4h 24m1 stop Washington, D.C. Dulles Intl

$484United Airlines

Wed, Oct 21 - Sat, Oct 24

Cheap last minute flights

Enter your travel dates to find the best prices.

4:38 pm - 7:44 pmCLE Cleveland Hopkins Intl-GSP Greenville

27h 06m2 stops Fort Lauderdale Tampa

6:55 pm - 9:07 amGSP Greenville-CLE Cleveland Hopkins Intl

14h 12m1 stop Orlando Sanford Intl

$387Multiple Airlines

Tue, Sep 8 - Fri, Sep 11

10:37 am - 2:20 pmCLE Cleveland Hopkins Intl-GSP Greenville

3h 43m1 stop Washington, D.C. Dulles Intl

10:25 am - 2:10 pmGSP Greenville-CLE Cleveland Hopkins Intl

3h 45m1 stop Washington, D.C. Dulles Intl

$435United Airlines

Wed, Sep 9 - Thu, Sep 10

6:30 am - 3:06 pmCLE Cleveland Hopkins Intl-GSP Greenville

8h 36m1 stop Tampa

6:55 pm - 9:07 amGSP Greenville-CLE Cleveland Hopkins Intl

14h 12m1 stop Orlando Sanford Intl

$499Multiple Airlines

Tue, Sep 8 - Fri, Sep 11

6:00 am - 3:43 pmCLE Cleveland Hopkins Intl-GSP Greenville

9h 43m1 stop Orlando

6:55 pm - 9:07 amGSP Greenville-CLE Cleveland Hopkins Intl

14h 12m1 stop Orlando Sanford Intl

$530Multiple Airlines

Mon, Sep 7 - Fri, Sep 11

4:16 pm - 9:18 pmCLE Cleveland Hopkins Intl-GSP Greenville

5h 02m1 stop Chicago O'Hare Intl

4:00 pm - 9:51 pmGSP Greenville-CLE Cleveland Hopkins Intl

5h 51m1 stop Newark

$608United Airlines

Tue, Sep 8 - Fri, Sep 11

10:37 am - 2:20 pmCLE Cleveland Hopkins Intl-GSP Greenville

3h 43m1 stop Washington, D.C. Dulles Intl

10:25 am - 2:10 pmGSP Greenville-CLE Cleveland Hopkins Intl

3h 45m1 stop Washington, D.C. Dulles Intl

$608United Airlines

Wed, Sep 9 - Thu, Sep 10

11:40 am - 9:00 pmCLE Cleveland Hopkins Intl-GSP Greenville

9h 20m2 stops Baltimore/Washington Nashville Intl

4:40 pm - 10:00 pmGSP Greenville-CLE Cleveland Hopkins Intl

5h 20m1 stop Baltimore/Washington

$613Southwest

Tue, Sep 8 - Fri, Sep 11

11:40 am - 9:00 pmCLE Cleveland Hopkins Intl-GSP Greenville

9h 20m2 stops Baltimore/Washington Nashville Intl

7:00 am - 5:30 pmGSP Greenville-CLE Cleveland Hopkins Intl

10h 30m2 stops Nashville Intl Baltimore/Washington

$624Southwest

Tue, Sep 8 - Fri, Sep 11

6:43 am - 10:15 amCLE Cleveland Hopkins Intl-GSP Greenville

3h 32m1 stop Detroit Metropolitan Wayne County

7:00 am - 11:58 amGSP Greenville-CLE Cleveland Hopkins Intl

4h 58m1 stop Atlanta Hartsfield-Jackson

$691Delta

Mon, Sep 7 - Fri, Sep 11

10:24 am - 4:15 pmCLE Cleveland Hopkins Intl-GSP Greenville

5h 51m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

7:00 am - 11:58 amGSP Greenville-CLE Cleveland Hopkins Intl

4h 58m1 stop Atlanta Hartsfield-Jackson

$2,463Delta

Mon, Sep 7 - Fri, Sep 11

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United Airlines flights from Cleveland to Greenville

Our best United Airlines deals on Cleveland to Greenville flight tickets

United Airlines

Sep 9

CLE10:37 amCleveland Hopkins Intl

3h 43m

1 stop

GSP2:20 pmGreenville

Sep 10

GSP10:25 amGreenville

3h 45m

1 stop

CLE2:10 pmCleveland Hopkins Intl

$435

United Airlines

Sep 8

CLE4:16 pmCleveland Hopkins Intl

5h 02m

1 stop

GSP9:18 pmGreenville

Sep 11

GSP4:00 pmGreenville

5h 51m

1 stop

CLE9:51 pmCleveland Hopkins Intl

$608

United Airlines

Sep 9

CLE10:37 amCleveland Hopkins Intl

3h 43m

1 stop

GSP2:20 pmGreenville

Sep 10

GSP10:25 amGreenville

3h 45m

1 stop

CLE2:10 pmCleveland Hopkins Intl

$640

Delta flights from Cleveland to Greenville

Our best Delta deals on Cleveland to Greenville flight tickets

Delta

Oct 7

CLE7:05 amCleveland Hopkins Intl

5h 55m

1 stop

GSP1:00 pmGreenville

Oct 13

GSP6:57 pmGreenville

4h 49m

1 stop

CLE11:46 pmCleveland Hopkins Intl

$279

Delta

Oct 2

CLE5:06 pmCleveland Hopkins Intl

4h 44m

1 stop

GSP9:50 pmGreenville

Oct 6

GSP7:00 amGreenville

5h 03m

1 stop

CLE12:03 pmCleveland Hopkins Intl

$291

Delta

Oct 2

CLE5:06 pmCleveland Hopkins Intl

5h 54m

1 stop

GSP11:00 pmGreenville

Oct 8

GSP5:40 amGreenville

4h 31m

1 stop

CLE10:11 amCleveland Hopkins Intl

$318

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Tue 10/6

3:45 pm-7:44 pm

2 stops27h 59m

Greenville

Mon 10/12

8:32 pm-8:57 am

1 stop12h 25m

$221

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Fri 10/9

9:59 pm-1:40 pm

1 stop15h 41m

Greenville

Mon 10/12

8:32 pm-8:57 am

1 stop12h 25m

$234

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Wed 10/14

6:10 am-10:20 am

1 stop4h 10m

Greenville

Tue 10/20

5:40 am-12:03 pm

1 stop6h 23m

$279

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Wed 10/7

7:05 am-1:00 pm

1 stop5h 55m

Greenville

Tue 10/13

6:57 pm-11:46 pm

1 stop4h 49m

$279

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Mon 10/26

10:23 am-6:08 pm

1 stop7h 45m

Greenville

Mon 11/2

4:37 pm-11:53 pm

1 stop7h 16m

$279

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Sat 10/24

12:51 pm-6:08 pm

1 stop5h 17m

Greenville

Sat 10/31

6:01 am-12:16 pm

1 stop6h 15m

$279

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Wed 10/14

4:20 pm-8:05 pm

1 stop3h 45m

Greenville

Tue 10/20

7:00 am-12:55 pm

1 stop5h 55m

$279

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Wed 10/21

6:15 am-12:40 pm

1 stop6h 25m

Greenville

Sat 10/24

6:40 am-12:55 pm

2 stops6h 15m

$284

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Sat 10/3

7:00 am-7:00 pm

2 stops12h 00m

Greenville

Mon 10/5

7:35 pm-11:59 pm

1 stop4h 24m

$457

Quickest round-trip

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Wed 10/21

4:23 pm-9:17 pm

1 stop4h 54m

Greenville

Sat 10/24

7:35 pm-11:59 pm

1 stop4h 24m

$484

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Cleveland to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Cleveland and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $298 to $368.
The lowest price recently found on this route was $221.

What is the cheapest month to fly to Greenville?

The month of January is another great option to travel to Greenville, with average flight prices from Cleveland averaging around $312.

How have Cleveland to Greenville flight prices changed over time?

As of September 2026, prices for Cleveland to Greenville flights are approximately 16% cheaper when compared to flights at the same time last year.

When to book flights from Cleveland to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Greenville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Cleveland to Greenville (CLE to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Greenville

Best Price Found	$120
Fastest flight time	3h 25m
Direct flights	None

The best one-way flight to Greenville from Cleveland in the past 72 hours is $120. The best round-trip flight deal from Cleveland to Greenville found on momondo in the last 72 hours is $221.

The fastest flight from Cleveland to Greenville takes 3h 25m

There are no direct flights from Cleveland to Greenville. There are no popular flight routes from Cleveland to Greenville.

Search flight deals

Frequently asked questions about flying from Cleveland to Greenville

How far is Cleveland Hopkins Intl to Greenville by plane?
There are 460.5 mi between Cleveland Hopkins Intl and Greenville. In terms of flight time, this usually takes a little over 3h 25m.
When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Greenville Airport?
Prices for flights from Cleveland Hopkins Intl Airport to Greenville Airport refresh daily.
How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Greenville Airport?
There are 4 operators available for flights from Cleveland Hopkins Intl Airport to Greenville Airport as of September 2026.
How old do you have to be to fly from Cleveland Hopkins Intl Airport to Greenville Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Cleveland to Greenville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Cleveland to Greenville is Delta (41% of total bookings). The next most popular airlines are American Airlines (35%), Southwest (14%), and United Airlines (9%).

Best airlines flying from Cleveland to Greenville

Compare and see reviews for airlines that fly from Cleveland to Greenville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $241	Free Cancellation	Rating 7.1 12,044 reviews	Search American Airlines flights
Delta	PriceFrom $246	Free Cancellation	Rating 7.8 8,573 reviews	Search Delta flights
Southwest	PriceFrom $254	Free Cancellation	Rating 8.0 4,200 reviews	Search Southwest flights
United Airlines	PriceFrom $266	Free Cancellation	Rating 7.4 10,171 reviews	Search United Airlines flights

Anderson

Simpsonville

Greenwood

Greer

Duncan

Seneca

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Greenville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Cleveland to Greenville for you.

Can I find flights from Cleveland to Greenville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Cleveland to Greenville flights to just show those with flexible booking policies.

How can momondo help me find flights from Cleveland to Greenville?

Once you have performed a search for Cleveland to Greenville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cleveland to Greenville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cleveland to Greenville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Cleveland to Greenville from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Greenville departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Cleveland to Greenville

Our best United Airlines deals on Cleveland to Greenville flight tickets

Delta flights from Cleveland to Greenville

Our best Delta deals on Cleveland to Greenville flight tickets

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How to get the cheapest flight ticket from Cleveland to Greenville

What is the typical price of a round-trip flight between Cleveland and Greenville?

What is the cheapest month to fly to Greenville?

How have Cleveland to Greenville flight prices changed over time?

What is the cheapest airline that flies from Cleveland Hopkins Intl to Greenville?

What airlines fly to Greenville?

When to book flights from Cleveland to Greenville

Cheap Cleveland to Greenville (CLE to GSP) flight deals and tips

Best Price Found

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Direct flights

Frequently asked questions about flying from Cleveland to Greenville

Best airlines flying from Cleveland to Greenville

Compare and see reviews for airlines that fly from Cleveland to Greenville with momondo

Traveling to a place near Greenville?

Why use momondo?

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing South Carolina

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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