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Cheap flights from Chicago to Panama City from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Panama City departing on 10/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

United Airlines Logo
10:45 am - 1:27 pmORD-ECP
2h 42mnonstop
United Airlines Logo
2:10 pm - 4:54 pmECP-ORD
2h 44mnonstop
$139United Airlines
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Fri, Dec 19 - Wed, Dec 24
Southwest Logo
5:35 am - 9:25 amMDW-ECP
3h 50m1 stop
Southwest Logo
10:15 am - 7:05 pmECP-MDW
8h 50m2 stops
$156Southwest
Find Deal
Wed, Nov 12 - Sat, Nov 15
American Airlines Logo
6:07 am - 1:12 pmORD-ECP
7h 05m1 stop
American Airlines Logo
1:21 pm - 9:23 pmECP-ORD
8h 02m1 stop
$159American Airlines
Find Deal
Sat, Nov 1 - Sat, Nov 8
American Airlines Logo
9:53 am - 4:44 pmORD-ECP
6h 51m2 stops
American Airlines Logo
1:19 pm - 9:23 pmECP-ORD
8h 04m1 stop
$164American Airlines
Find Deal
Tue, Nov 4 - Fri, Nov 7
American Airlines Logo
6:00 am - 12:54 pmORD-ECP
6h 54m1 stop
American Airlines Logo
1:27 pm - 7:22 pmECP-ORD
5h 55m1 stop
$185American Airlines
Find Deal
Thu, Jan 29 - Sun, Feb 1
Southwest Logo
6:45 pm - 10:35 pmMDW-ECP
3h 50m1 stop
Southwest Logo
9:25 am - 8:35 pmECP-MDW
11h 10m1 stop
$188Southwest
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Mon, Oct 13 - Thu, Oct 16
Delta Logo
4:21 pm - 8:31 pmORD-ECP
4h 10m1 stop
Delta Logo
6:00 am - 10:20 amECP-ORD
4h 20m1 stop
$197Delta
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Tue, Dec 2 - Fri, Dec 5
Delta Logo
4:23 pm - 11:10 pmMDW-ECP
6h 47m1 stop
Delta Logo
5:00 pm - 10:14 pmECP-MDW
5h 14m1 stop
$197Delta
Find Deal
Sat, Nov 1 - Sat, Nov 8
United Airlines Logo
10:50 am - 1:09 pmORD-ECP
2h 19mnonstop
United Airlines Logo
2:15 pm - 4:46 pmECP-ORD
2h 31mnonstop
$201United Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 11
American Airlines Logo
6:07 am - 1:12 pmORD-ECP
7h 05m1 stop
American Airlines Logo
1:47 pm - 7:16 pmECP-ORD
5h 29m1 stop
$229American Airlines
Find Deal
Tue, Oct 7 - Wed, Oct 15

American Airlines flights from Chicago to Panama City, Florida

Our best American Airlines deals on Chicago to Panama City, Florida flight tickets
American Airlines
Nov 1
ORD6:07 amChicago O'Hare Intl
7h 05m
1 stop
ECP1:12 pmPanama City NW Florida Beaches
Nov 8
ECP1:21 pmPanama City NW Florida Beaches
8h 02m
1 stop
ORD9:23 pmChicago O'Hare Intl
$159
Find similar
American Airlines
Nov 4
ORD9:53 amChicago O'Hare Intl
6h 51m
2 stops
ECP4:44 pmPanama City NW Florida Beaches
Nov 7
ECP1:19 pmPanama City NW Florida Beaches
8h 04m
1 stop
ORD9:23 pmChicago O'Hare Intl
$164
Find similar
American Airlines
Jan 29
ORD6:00 amChicago O'Hare Intl
6h 54m
1 stop
ECP12:54 pmPanama City NW Florida Beaches
Feb 1
ECP1:27 pmPanama City NW Florida Beaches
5h 55m
1 stop
ORD7:22 pmChicago O'Hare Intl
$185
Find similar

Delta flights from Chicago to Panama City, Florida

Our best Delta deals on Chicago to Panama City, Florida flight tickets
Delta
Nov 1
MDW4:23 pmChicago Midway
6h 47m
1 stop
ECP11:10 pmPanama City NW Florida Beaches
Nov 8
ECP5:00 pmPanama City NW Florida Beaches
5h 14m
1 stop
MDW10:14 pmChicago Midway
$197
Find similar
Delta
Dec 23
MDW9:29 amChicago Midway
10h 28m
2 stops
ECP7:57 pmPanama City NW Florida Beaches
Dec 30
ECP6:59 pmPanama City NW Florida Beaches
16h 07m
2 stops
MDW11:06 amChicago Midway
$305
Find similar
Delta
Nov 7
ORD10:30 amChicago O'Hare Intl
12h 40m
2 stops
ECP11:10 pmPanama City NW Florida Beaches
Nov 10
ECP6:40 pmPanama City NW Florida Beaches
5h 21m
1 stop
ORD12:01 amChicago O'Hare Intl
$306
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Chicago to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Fri 12/19

10:45 am-1:27 pm

Nonstop2h 42m

Panama City NW Florida Beaches

Wed 12/24

2:10 pm-4:54 pm

Nonstop2h 44m

$139

ChicagoPanama City

MDW - ECP

MDWECP

Chicago Midway

Wed 11/12

5:35 am-9:25 am

1 stop3h 50m

Panama City NW Florida Beaches

Sat 11/15

10:15 am-7:05 pm

2 stops8h 50m

$156

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Sat 11/1

6:07 am-1:12 pm

1 stop7h 05m

Panama City NW Florida Beaches

Sat 11/8

1:21 pm-9:23 pm

1 stop8h 02m

$159

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Tue 11/4

9:53 am-4:44 pm

2 stops6h 51m

Panama City NW Florida Beaches

Fri 11/7

1:19 pm-9:23 pm

1 stop8h 04m

$164

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Thu 1/29

6:00 am-12:54 pm

1 stop6h 54m

Panama City NW Florida Beaches

Sun 2/1

1:27 pm-7:22 pm

1 stop5h 55m

$185

ChicagoPanama City

MDW - ECP

MDWECP

Chicago Midway

Mon 10/13

6:45 pm-10:35 pm

1 stop3h 50m

Panama City NW Florida Beaches

Thu 10/16

9:25 am-8:35 pm

1 stop11h 10m

$188

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Tue 12/2

4:21 pm-8:31 pm

1 stop4h 10m

Panama City NW Florida Beaches

Fri 12/5

6:00 am-10:20 am

1 stop4h 20m

$197

ChicagoPanama City

MDW - ECP

MDWECP

Chicago Midway

Sat 11/1

4:23 pm-11:10 pm

1 stop6h 47m

Panama City NW Florida Beaches

Sat 11/8

5:00 pm-10:14 pm

1 stop5h 14m

$197

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Tue 3/10

10:50 am-1:09 pm

Nonstop2h 19m

Panama City NW Florida Beaches

Wed 3/11

2:15 pm-4:46 pm

Nonstop2h 31m

$201

ChicagoPanama City

ORD - ECP

ORDECP

Chicago O'Hare Intl

Tue 10/7

6:07 am-1:12 pm

1 stop7h 05m

Panama City NW Florida Beaches

Wed 10/15

1:47 pm-7:16 pm

1 stop5h 29m

$229

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Chicago is in January. Flight prices, which tend to average around $288, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Chicago averaging around $314.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Tuesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $333. On the other hand, Saturday is the most expensive day to depart from Chicago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $507.

What is the cheapest Chicago to Panama City NW Florida Beaches flight route?

Fly from Chicago O'Hare Intl to Panama City NW Florida Beaches for the best Chicago - Panama City NW Florida Beaches flight prices

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $411 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Chicago for as low as $369 on momondo.

What cabin class options are available on Chicago to Panama City NW Florida Beaches flights?

There are 3 cabin classes available to choose from on Chicago to Panama City NW Florida Beaches flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City, Florida flights?

No. A direct flight is the cheapest option for a flight between Chicago to Panama City, Florida.

How have Chicago to Panama City, Florida flight prices changed over time?

As of September 2025, prices for Chicago to Panama City, Florida flights are approximately 52% cheaper when compared to flights at the same time last year.

When to book flights from Chicago to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Panama City, Florida (CHI to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City, Florida

Best Price Found

$265

Fastest flight time

2h 05m

Direct flights

Every day

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Chicago in the past 72 hours is $265. The best round-trip flight deal from Chicago to Panama City, Florida found on momondo in the last 72 hours is $139.
The fastest flight from Chicago to Panama City, Florida takes 2h 05m
Direct flights go from Chicago to Panama City, Florida every day.
There is 1 airport near Panama City, Florida: Panama City NW Florida Beaches (ECP)
Search flight deals

  • How far is Chicago to Panama City NW Florida Beaches by plane?

    The straight-line distance from Chicago to Panama City NW Florida Beaches is 816.3 mi. By plane, this route typically takes 2h 19m.

  • When did momondo last update prices for flights from Chicago to Panama City NW Florida Beaches Airport?

    Prices for flights from Chicago to Panama City NW Florida Beaches Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Chicago to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago to Panama City, Florida?

  • What is the most popular airline from Chicago to Panama City, Florida?

Best airlines flying from Chicago to Panama City, Florida

Compare and see reviews for airlines that fly from Chicago to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
7,954 reviews
Search Delta flights
SouthwestPriceFrom $227Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
United AirlinesPriceFrom $247Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights
American AirlinesPriceFrom $256Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Southwest Flights From Chicago to Panama City, Florida

    Southwest flight deals from Chicago to Panama City, Florida start from $227 round-trip. Over the 5 Southwest flights for this route in a normal week, average airfare is usually $395 round-trip - but some users have found much cheaper deals with momondo.

  • United Airlines Flights From Chicago to Panama City, Florida

    Across 8,929 United Airlines reviews on momondo, the average score is 7.4/10. United Airlines flies from Chicago to Panama City, Florida about 7 times each week, with ticket deals ranging from $247 to $455. Price data is based on momondo searches in the last 72 hours.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

Finding the right flight to Panama City from Chicago is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Flights from Chicago to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Panama City?

momondo helps you find the best flight between Chicago and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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