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Cheap flights from Chicago to Florence from $197

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Florence departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Chicago to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:10 pm - 11:38 pmORD-FLO
9h 28m2 stops
American Airlines Logo
11:09 am - 3:45 pmFLO-ORD
5h 36m1 stop
$494American Airlines
Find Deal
ter, mar 17 - sáb, mar 21
American Airlines Logo
1:10 pm - 11:38 pmORD-FLO
9h 28m2 stops
American Airlines Logo
2:30 pm - 10:16 pmFLO-ORD
8h 46m2 stops
$499American Airlines
Find Deal
ter, mar 17 - sáb, mar 21
American Airlines Logo
7:00 am - 2:05 pmORD-FLO
6h 05m1 stop
American Airlines Logo
5:13 am - 8:32 amFLO-ORD
4h 19m1 stop
$504American Airlines
Find Deal
ter, mar 17 - sáb, mar 21
American Airlines Logo
5:00 am - 10:24 amORD-FLO
4h 24m1 stop
American Airlines Logo
5:13 am - 1:44 pmFLO-ORD
9h 31m2 stops
$509American Airlines
Find Deal
ter, mar 17 - sáb, mar 21
American Airlines Logo
4:07 pm - 11:38 pmORD-FLO
6h 31m2 stops
American Airlines Logo
2:30 pm - 8:07 pmFLO-ORD
6h 37m2 stops
$514American Airlines
Find Deal
ter, mar 17 - sáb, mar 21
American Airlines Logo
6:35 pm - 11:41 pmORD-FLO
4h 06m1 stop
American Airlines Logo
5:15 am - 10:42 amFLO-ORD
6h 27m1 stop
$631American Airlines
Find Deal
qua, nov 26 - dom, nov 30
American Airlines Logo
10:15 am - 6:07 pmORD-FLO
6h 52m2 stops
American Airlines Logo
5:15 am - 10:42 amFLO-ORD
6h 27m1 stop
$696American Airlines
Find Deal
qua, nov 26 - dom, nov 30
American Airlines Logo
10:15 am - 6:07 pmORD-FLO
6h 52m2 stops
American Airlines Logo
5:15 am - 10:52 amFLO-ORD
6h 37m2 stops
$1,059American Airlines
Find Deal
qua, nov 26 - dom, nov 30

American Airlines flights from Chicago to Florence, South Carolina

Our best American Airlines deals on Chicago to Florence, South Carolina flight tickets
American Airlines
Mar 17
ORD1:10 pmChicago O'Hare Intl
9h 28m
2 stops
FLO11:38 pmFlorence
Mar 21
FLO11:09 amFlorence
5h 36m
1 stop
ORD3:45 pmChicago O'Hare Intl
$494
Find similar
American Airlines
Mar 17
ORD1:10 pmChicago O'Hare Intl
9h 28m
2 stops
FLO11:38 pmFlorence
Mar 21
FLO2:30 pmFlorence
8h 46m
2 stops
ORD10:16 pmChicago O'Hare Intl
$499
Find similar
American Airlines
Mar 17
ORD7:00 amChicago O'Hare Intl
6h 05m
1 stop
FLO2:05 pmFlorence
Mar 21
FLO5:13 amFlorence
4h 19m
1 stop
ORD8:32 amChicago O'Hare Intl
$504
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated novembro 5, 2025.
Use the filters below to find and compare flights from Chicago to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

ter 3/17

1:10 pm-11:38 pm

2 stops9h 28m

Florence

sáb 3/21

11:09 am-3:45 pm

1 stop5h 36m

$494

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

ter 3/17

1:10 pm-11:38 pm

2 stops9h 28m

Florence

sáb 3/21

2:30 pm-10:16 pm

2 stops8h 46m

$499

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

ter 3/17

7:00 am-2:05 pm

1 stop6h 05m

Florence

sáb 3/21

5:13 am-8:32 am

1 stop4h 19m

$504

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

ter 3/17

5:00 am-10:24 am

1 stop4h 24m

Florence

sáb 3/21

5:13 am-1:44 pm

2 stops9h 31m

$509

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

ter 3/17

4:07 pm-11:38 pm

2 stops6h 31m

Florence

sáb 3/21

2:30 pm-8:07 pm

2 stops6h 37m

$514

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

qua 11/26

6:35 pm-11:41 pm

1 stop4h 06m

Florence

dom 11/30

5:15 am-10:42 am

1 stop6h 27m

$631

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

qua 11/26

10:15 am-6:07 pm

2 stops6h 52m

Florence

dom 11/30

5:15 am-10:42 am

1 stop6h 27m

$696

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

qua 11/26

10:15 am-6:07 pm

2 stops6h 52m

Florence

dom 11/30

5:15 am-10:52 am

2 stops6h 37m

$1,059

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

qui 1/15

10:10 am-5:09 pm

1 stop5h 59m

$197

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

qui 1/15

9:45 am-5:09 pm

2 stops6h 24m

$202

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Chicago to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Chicago is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $437. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Chicago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $449.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the afternoon. momondo users have found flights departing from Chicago to Florence, South Carolina in the afternoon for as low as $437. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $477 per ticket.

When to book flights from Chicago to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Florence, South Carolina (CHI to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Florence, South Carolina

Direct flights

None
There are no direct flights from Chicago to Florence, South Carolina. There are no popular flight routes from Chicago to Florence, South Carolina.
Search flight deals

  • How far is Chicago to Florence by plane?

    There are 680.6 mi between Chicago and Florence. Flights usually cover this in 4h 06m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago to Florence Airport?

    Prices for flights from Chicago to Florence Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Florence Airport?

  • How old do you have to be to fly from Chicago to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Chicago to Florence, South Carolina

Compare and see reviews for airlines that fly from Chicago to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $290Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Florence?

It is quick and easy to find Chicago to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Chicago to Florence with flexible booking policies on momondo?

All flight searches from Chicago to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Florence.

I’m not ready to book a flight from Chicago to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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