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Cheap flights from Chicago to Florence from $452

1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Chicago to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:45 pm - 10:55 pmORD  Chicago O'Hare Intl-FLO Florence
5h 10m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 11:05 amFLO  Florence-ORD Chicago O'Hare Intl
5h 41m1 stop Charlotte Douglas
$452American Airlines
Sat, Dec 5 - Sat, Dec 12
American Airlines Logo
8:10 am - 3:12 pmORD  Chicago O'Hare Intl-FLO Florence
6h 02m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 7:59 pmFLO  Florence-ORD Chicago O'Hare Intl
6h 24m1 stop Charlotte Douglas
$521American Airlines
Wed, Dec 16 - Sat, Dec 19
American Airlines Logo
7:40 am - 3:13 pmORD  Chicago O'Hare Intl-FLO Florence
6h 33m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 5:45 pmFLO  Florence-ORD Chicago O'Hare Intl
4h 10m1 stop Charlotte Douglas
$521American Airlines
Sat, Dec 12 - Tue, Dec 22
American Airlines Logo
9:00 am - 3:13 pmORD  Chicago O'Hare Intl-FLO Florence
5h 13m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 7:59 pmFLO  Florence-ORD Chicago O'Hare Intl
6h 24m1 stop Charlotte Douglas
$521American Airlines
Sat, Dec 12 - Sat, Dec 19
American Airlines Logo
4:45 pm - 10:55 pmORD  Chicago O'Hare Intl-FLO Florence
5h 10m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 7:59 pmFLO  Florence-ORD Chicago O'Hare Intl
6h 24m1 stop Charlotte Douglas
$521American Airlines
Tue, Dec 15 - Sat, Dec 19
American Airlines Logo
8:10 am - 3:19 pmORD  Chicago O'Hare Intl-FLO Florence
6h 09m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 5:45 pmFLO  Florence-ORD Chicago O'Hare Intl
4h 10m1 stop Charlotte Douglas
$521American Airlines
Tue, Dec 15 - Wed, Dec 23
American Airlines Logo
9:00 am - 3:12 pmORD  Chicago O'Hare Intl-FLO Florence
5h 12m1 stop Charlotte Douglas
American Airlines Logo
5:09 am - 9:24 amFLO  Florence-ORD Chicago O'Hare Intl
5h 15m1 stop Charlotte Douglas
$521American Airlines
Wed, Dec 16 - Wed, Dec 23
American Airlines Logo
8:10 am - 3:19 pmORD  Chicago O'Hare Intl-FLO Florence
6h 09m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 7:59 pmFLO  Florence-ORD Chicago O'Hare Intl
6h 24m1 stop Charlotte Douglas
$521American Airlines
Tue, Dec 15 - Tue, Dec 22
American Airlines Logo
7:40 am - 3:13 pmORD  Chicago O'Hare Intl-FLO Florence
6h 33m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 7:59 pmFLO  Florence-ORD Chicago O'Hare Intl
6h 24m1 stop Charlotte Douglas
$521American Airlines
Sat, Dec 12 - Wed, Dec 23
American Airlines Logo
8:10 am - 3:12 pmORD  Chicago O'Hare Intl-FLO Florence
6h 02m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 5:45 pmFLO  Florence-ORD Chicago O'Hare Intl
4h 10m1 stop Charlotte Douglas
$521American Airlines
Wed, Dec 16 - Tue, Dec 22

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American Airlines flights from Chicago to Florence, South Carolina

Our best American Airlines deals on Chicago to Florence, South Carolina flight tickets
American Airlines
Dec 5
ORD4:45 pmChicago O'Hare Intl
5h 10m
1 stop
FLO10:55 pmFlorence
Dec 12
FLO6:24 amFlorence
5h 41m
1 stop
ORD11:05 amChicago O'Hare Intl
$452
American Airlines
Dec 12
ORD7:40 amChicago O'Hare Intl
6h 33m
1 stop
FLO3:13 pmFlorence
Dec 23
FLO2:35 pmFlorence
6h 24m
1 stop
ORD7:59 pmChicago O'Hare Intl
$521
American Airlines
Dec 12
ORD9:00 amChicago O'Hare Intl
5h 13m
1 stop
FLO3:13 pmFlorence
Dec 20
FLO5:09 amFlorence
5h 15m
1 stop
ORD9:24 amChicago O'Hare Intl
$536

momondo Fare Finder

 
Use the filters below to find and compare flights from Chicago to Florence, South Carolina that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Sat 12/5

4:45 pm-10:55 pm

1 stop5h 10m

Florence

Sat 12/12

6:24 am-11:05 am

1 stop5h 41m

$452

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Wed 12/16

8:10 am-3:12 pm

1 stop6h 02m

Florence

Sat 12/19

2:35 pm-7:59 pm

1 stop6h 24m

$521

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Sat 12/12

7:40 am-3:13 pm

1 stop6h 33m

Florence

Tue 12/22

2:35 pm-5:45 pm

1 stop4h 10m

$521

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Sat 12/12

9:00 am-3:13 pm

1 stop5h 13m

Florence

Sat 12/19

2:35 pm-7:59 pm

1 stop6h 24m

$521

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Tue 12/15

4:45 pm-10:55 pm

1 stop5h 10m

Florence

Sat 12/19

2:35 pm-7:59 pm

1 stop6h 24m

$521

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Tue 12/15

8:10 am-3:19 pm

1 stop6h 09m

Florence

Wed 12/23

2:35 pm-5:45 pm

1 stop4h 10m

$521

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Wed 12/16

9:00 am-3:12 pm

1 stop5h 12m

Florence

Wed 12/23

5:09 am-9:24 am

1 stop5h 15m

$521

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Tue 12/15

8:10 am-3:19 pm

1 stop6h 09m

Florence

Tue 12/22

2:35 pm-7:59 pm

1 stop6h 24m

$521

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Sat 12/12

7:40 am-3:13 pm

1 stop6h 33m

Florence

Wed 12/23

2:35 pm-7:59 pm

1 stop6h 24m

$521
Quickest round-trip

ChicagoFlorence

ORD Chicago O'Hare Intl - FLO Florence

ORDFLO

Chicago O'Hare Intl

Wed 12/16

8:10 am-3:12 pm

1 stop6h 02m

Florence

Tue 12/22

2:35 pm-5:45 pm

1 stop4h 10m

$521

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Chicago to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Chicago according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Chicago to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Florence, South Carolina (CHI to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Florence, South Carolina

Best Price Found

$452

Fastest flight time

5h 04m

Direct flights

None
The best flight deal from Chicago to Florence, South Carolina found on momondo in the last 72 hours is $452
The fastest flight from Chicago to Florence, South Carolina takes 5h 04m
There are no direct flights from Chicago to Florence, South Carolina. There are no popular flight routes from Chicago to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Chicago to Florence, South Carolina

  • How far is Chicago to Florence by plane?

    There are 680.6 mi between Chicago and Florence. Flights usually cover this in 5h 04m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago to Florence Airport?

    Prices for flights from Chicago to Florence Airport refresh daily.

  • How old do you have to be to fly from Chicago to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Lake City
Hartsville
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Florence?

It is quick and easy to find Chicago to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Chicago to Florence with flexible booking policies on momondo?

All flight searches from Chicago to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Florence.

I’m not ready to book a flight from Chicago to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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