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Cheap flights from Tyler to Knoxville from $593

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Tyler to Knoxville departing on 8/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Tyler to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:59 am - 4:43 pm
TYR
-
TYS
4h 44m
1 stop
American Airlines Logo
1:46 pm - 5:05 pm
TYS
-
TYR
4h 19m
1 stop
$593American Airlines
Fri, Aug 7 - Tue, Aug 11
American Airlines Logo
5:07 am - 11:18 am
TYR
-
TYS
5h 11m
1 stop
American Airlines Logo
12:09 pm - 10:33 pm
TYS
-
TYR
11h 24m
2 stops
$599American Airlines
Fri, Aug 7 - Tue, Aug 11
American Airlines Logo
5:07 am - 1:31 pm
TYR
-
TYS
7h 24m
2 stops
American Airlines Logo
12:09 pm - 10:33 pm
TYS
-
TYR
11h 24m
2 stops
$604American Airlines
Fri, Aug 7 - Tue, Aug 11

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American Airlines flights from Tyler to Knoxville

Our best American Airlines deals on Tyler to Knoxville flight tickets
American Airlines
Aug 7
TYR10:59 amTyler Pounds Field
4h 44m
1 stop
TYS4:43 pmKnoxville McGhee Tyson
Aug 11
TYS1:46 pmKnoxville McGhee Tyson
4h 19m
1 stop
TYR5:05 pmTyler Pounds Field
$593
American Airlines
Aug 7
TYR5:07 amTyler Pounds Field
5h 11m
1 stop
TYS11:18 amKnoxville McGhee Tyson
Aug 11
TYS12:09 pmKnoxville McGhee Tyson
11h 24m
2 stops
TYR10:33 pmTyler Pounds Field
$599
American Airlines
Aug 7
TYR5:07 amTyler Pounds Field
7h 24m
2 stops
TYS1:31 pmKnoxville McGhee Tyson
Aug 11
TYS12:09 pmKnoxville McGhee Tyson
11h 24m
2 stops
TYR10:33 pmTyler Pounds Field
$604

momondo Fare Finder

 
Customize your flight search to find flights from Tyler to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Tyler to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Fri 8/7

10:59 am-4:43 pm

1 stop4h 44m

Knoxville McGhee Tyson

Tue 8/11

1:46 pm-5:05 pm

1 stop4h 19m

$593

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Fri 8/7

5:07 am-11:18 am

1 stop5h 11m

Knoxville McGhee Tyson

Tue 8/11

12:09 pm-10:33 pm

2 stops11h 24m

$599

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Fri 8/7

5:07 am-1:31 pm

2 stops7h 24m

Knoxville McGhee Tyson

Tue 8/11

12:09 pm-10:33 pm

2 stops11h 24m

$604

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Knoxville from

How to get the cheapest flight ticket from Tyler to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Knoxville?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Knoxville from Tyler according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When to book flights from Tyler to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Tyler to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tyler to Knoxville (TYR to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tyler to Knoxville

Fastest flight time

4h 43m

Direct flights

None
The fastest flight from Tyler to Knoxville takes 4h 43m
There are no direct flights from Tyler to Knoxville. There are no popular flight routes from Tyler to Knoxville.
Search flight deals

Frequently asked questions about flying from Tyler to Knoxville

  • How far is Tyler Pounds Field to Knoxville McGhee Tyson by plane?

    The straight-line distance from Tyler Pounds Field to Knoxville McGhee Tyson is 695.8 mi. By plane, this route typically takes 4h 43m.

  • When did momondo last update prices for flights from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How old do you have to be to fly from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Tyler to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Tyler.

Can I find flights from Tyler to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Tyler on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Tyler to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Tyler. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tyler to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tyler to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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