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Cheap flights from Tyler to Knoxville from $470

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Tyler to Knoxville departing on 3/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Tyler to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:35 pm - 11:51 pm
TYR
-
TYS
4h 16m
1 stop
American Airlines Logo
5:40 am - 9:56 am
TYS
-
TYR
5h 16m
1 stop
$470American Airlines
Thu, Mar 26 - Sun, Mar 29
American Airlines Logo
6:05 am - 11:31 am
TYR
-
TYS
4h 26m
1 stop
American Airlines Logo
6:21 pm - 11:47 pm
TYS
-
TYR
6h 26m
1 stop
$515American Airlines
Wed, Feb 25 - Sun, Mar 1
American Airlines Logo
10:26 am - 11:59 pm
TYR
-
TYS
12h 33m
2 stops
American Airlines Logo
5:40 am - 9:56 am
TYS
-
TYR
5h 16m
1 stop
$521American Airlines
Wed, Feb 25 - Sun, Mar 1
American Airlines Logo
6:05 am - 3:30 pm
TYR
-
TYS
8h 25m
2 stops
American Airlines Logo
6:05 am - 6:05 pm
TYS
-
TYR
13h 00m
2 stops
$633American Airlines
Wed, Feb 25 - Sun, Mar 1
American Airlines Logo
6:05 am - 5:16 pm
TYR
-
TYS
10h 11m
2 stops
American Airlines Logo
5:40 am - 9:56 am
TYS
-
TYR
5h 16m
1 stop
$721American Airlines
Thu, Mar 26 - Sun, Mar 29
American Airlines Logo
6:05 am - 5:16 pm
TYR
-
TYS
10h 11m
2 stops
American Airlines Logo
4:15 pm - 11:47 pm
TYS
-
TYR
8h 32m
2 stops
$939American Airlines
Thu, Mar 26 - Sun, Mar 29

American Airlines flights from Tyler to Knoxville

Our best American Airlines deals on Tyler to Knoxville flight tickets
American Airlines
Mar 26
TYR6:35 pmTyler Pounds Field
4h 16m
1 stop
TYS11:51 pmKnoxville McGhee Tyson
Mar 29
TYS5:40 amKnoxville McGhee Tyson
5h 16m
1 stop
TYR9:56 amTyler Pounds Field
$470
American Airlines
Feb 25
TYR6:05 amTyler Pounds Field
4h 26m
1 stop
TYS11:31 amKnoxville McGhee Tyson
Mar 1
TYS6:21 pmKnoxville McGhee Tyson
6h 26m
1 stop
TYR11:47 pmTyler Pounds Field
$515
American Airlines
Feb 25
TYR10:26 amTyler Pounds Field
12h 33m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
Mar 1
TYS5:40 amKnoxville McGhee Tyson
5h 16m
1 stop
TYR9:56 amTyler Pounds Field
$521

momondo Fare Finder

 
Customize your flight search to find flights from Tyler to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Tyler to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Thu 3/26

6:35 pm-11:51 pm

1 stop4h 16m

Knoxville McGhee Tyson

Sun 3/29

5:40 am-9:56 am

1 stop5h 16m

$470

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Wed 2/25

6:05 am-11:31 am

1 stop4h 26m

Knoxville McGhee Tyson

Sun 3/1

6:21 pm-11:47 pm

1 stop6h 26m

$515

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Wed 2/25

10:26 am-11:59 pm

2 stops12h 33m

Knoxville McGhee Tyson

Sun 3/1

5:40 am-9:56 am

1 stop5h 16m

$521

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Wed 2/25

6:05 am-3:30 pm

2 stops8h 25m

Knoxville McGhee Tyson

Sun 3/1

6:05 am-6:05 pm

2 stops13h 00m

$633

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Thu 3/26

6:05 am-5:16 pm

2 stops10h 11m

Knoxville McGhee Tyson

Sun 3/29

5:40 am-9:56 am

1 stop5h 16m

$721

TylerKnoxville

TYR - TYS

TYRTYS

Tyler Pounds Field

Thu 3/26

6:05 am-5:16 pm

2 stops10h 11m

Knoxville McGhee Tyson

Sun 3/29

4:15 pm-11:47 pm

2 stops8h 32m

$939

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Knoxville from

How to get the cheapest flight ticket from Tyler to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Tyler to Knoxville flights?

You could potentially save up to 1% on your flight if you consider stops on a Tyler to Knoxville flight.

When to book flights from Tyler to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Tyler to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tyler to Knoxville (TYR to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tyler to Knoxville

Fastest flight time

4h 16m

Direct flights

None
The fastest flight from Tyler to Knoxville takes 4h 16m
There are no direct flights from Tyler to Knoxville. There are no popular flight routes from Tyler to Knoxville.
Search flight deals

  • How far is Tyler Pounds Field to Knoxville McGhee Tyson by plane?

    The straight-line distance from Tyler Pounds Field to Knoxville McGhee Tyson is 695.8 mi. By plane, this route typically takes 4h 16m.

  • When did momondo last update prices for flights from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Tyler Pounds Field Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Tyler to Knoxville?

Best airlines flying from Tyler to Knoxville

Compare and see reviews for airlines that fly from Tyler to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $403Free CancellationRating
7.2
11,275 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Alcoa
Crossville
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Tyler to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Tyler.

Can I find flights from Tyler to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Tyler on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Tyler to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Tyler. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tyler to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tyler to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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