Cheap flights from Tampa to Missouri from $50

In general, December is the cheapest month to fly from Tampa to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $331. If you aren’t able to travel to Missouri during the month of December, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $343.

The cheapest day to depart from Tampa to Missouri is on a Friday when prices can be found for as low as $393. Flights from Tampa to Missouri on a Monday will generally be more expensive and average around $513. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Missouri is in the evening. momondo users have found flights departing from Tampa to Missouri in the evening for as low as $387. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly at noon, with an average ticket price of $489. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Tampa to Lambert-St Louis for the best Tampa - Missouri flight prices

You are more likely to see cheaper flights to Missouri from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $397 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Tampa for as low as $285 on momondo.

There is only 1 cabin class available to choose from on Tampa to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, American Airlines, and Southwest are the most popular carriers operating from Tampa to Missouri

Southwest, Frontier and Allegiant Air are the top three most popular airlines that fly to Missouri from Tampa according to our data. Southwest is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 7 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

As of October 2026, 3 flights take off from Tampa and land in Missouri each day. The most common flight departure time for this route is 6:00AM, with 56% of daily flights taking off at noon.

The number of flights available between Tampa and Missouri is 21 per week as of October 2026. The most frequent departure day is Mon, with 33% of weekly flights leaving on this day.