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Cheap flights from Tampa to Des Moines from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Des Moines departing on 6/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Tampa to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:20 am - 10:45 am
TPA
-
DSM
5h 25m
1 stop
Delta Logo
10:54 am - 8:19 pm
DSM
-
TPA
8h 25m
1 stop
$237Delta
Wed, Jul 22 - Tue, Jul 28
Multiple Airlines Logo
12:28 pm - 7:57 pm
TPA
-
DSM
8h 29m
1 stop
Multiple Airlines Logo
1:58 pm - 11:23 am
DSM
-
TPA
20h 25m
1 stop
$244Multiple Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
4:45 pm - 12:07 am
TPA
-
DSM
8h 22m
1 stop
American Airlines Logo
7:04 am - 1:04 pm
DSM
-
TPA
5h 00m
1 stop
$257American Airlines
Wed, Jul 1 - Wed, Jul 8
Frontier Logo
12:39 pm - 1:34 pm
TPA
-
DSM
25h 55m
1 stop
Frontier Logo
2:19 pm - 5:32 am
DSM
-
TPA
14h 13m
1 stop
$261Frontier
Thu, Aug 6 - Wed, Aug 12
Southwest Logo
2:00 pm - 9:40 pm
TPA
-
DSM
8h 40m
1 stop
Southwest Logo
5:20 am - 2:15 pm
DSM
-
TPA
7h 55m
2 stops
$262Southwest
Wed, Jul 22 - Tue, Jul 28
Frontier Logo
12:39 pm - 1:34 pm
TPA
-
DSM
25h 55m
1 stop
Frontier Logo
2:19 pm - 5:32 am
DSM
-
TPA
14h 13m
1 stop
$280Frontier
Thu, Jul 30 - Mon, Aug 3
Multiple Airlines Logo
10:32 pm - 9:27 pm
TPA
-
DSM
23h 55m
1 stop
Multiple Airlines Logo
5:02 pm - 11:49 am
DSM
-
TPA
17h 47m
2 stops
$295Multiple Airlines
Wed, Jun 10 - Sun, Jun 14
Southwest Logo
5:15 am - 11:25 am
TPA
-
DSM
7h 10m
1 stop
Southwest Logo
6:10 am - 2:55 pm
DSM
-
TPA
7h 45m
2 stops
$299Southwest
Thu, Aug 6 - Wed, Aug 12
Southwest Logo
11:30 am - 10:10 pm
TPA
-
DSM
11h 40m
2 stops
Southwest Logo
6:10 am - 2:55 pm
DSM
-
TPA
7h 45m
2 stops
$310Southwest
Thu, Aug 6 - Wed, Aug 12
Multiple Airlines Logo
7:05 am - 9:27 pm
TPA
-
DSM
15h 22m
2 stops
Multiple Airlines Logo
4:40 pm - 8:08 am
DSM
-
TPA
14h 28m
1 stop
$321Multiple Airlines
Thu, Jul 30 - Mon, Aug 3

American Airlines flights from Tampa to Des Moines

Our best American Airlines deals on Tampa to Des Moines flight tickets
American Airlines
Jul 1
TPA4:45 pmTampa
8h 22m
1 stop
DSM12:07 amDes Moines
Jul 8
DSM7:04 amDes Moines
5h 00m
1 stop
TPA1:04 pmTampa
$257
American Airlines
Jun 16
TPA12:12 pmTampa
10h 11m
1 stop
DSM9:23 pmDes Moines
Jun 22
DSM4:48 pmDes Moines
6h 09m
1 stop
TPA11:57 pmTampa
$342
American Airlines
Jun 19
TPA4:09 pmTampa
6h 49m
1 stop
DSM9:58 pmDes Moines
Jun 23
DSM5:00 amDes Moines
8h 34m
2 stops
TPA2:34 pmTampa
$347

United Airlines flights from Tampa to Des Moines

Our best United Airlines deals on Tampa to Des Moines flight tickets
United Airlines
Aug 14
TPA7:30 amTampa
7h 46m
1 stop
DSM2:16 pmDes Moines
Aug 17
DSM3:20 pmDes Moines
5h 21m
1 stop
TPA9:41 pmTampa
$379
United Airlines
Jul 22
TPA4:30 pmTampa
5h 52m
1 stop
DSM9:22 pmDes Moines
Jul 28
DSM6:00 amDes Moines
13h 39m
2 stops
TPA8:39 pmTampa
$422
United Airlines
Jul 9
TPA7:50 amTampa
7h 38m
1 stop
DSM2:28 pmDes Moines
Jul 14
DSM6:00 amDes Moines
8h 25m
2 stops
TPA3:25 pmTampa
$437

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 7/22

6:20 am-10:45 am

1 stop5h 25m

Des Moines

Tue 7/28

10:54 am-8:19 pm

1 stop8h 25m

$237

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 9/3

12:28 pm-7:57 pm

1 stop8h 29m

Des Moines

Sun 9/6

1:58 pm-11:23 am

1 stop20h 25m

$244
Quickest round-trip

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 7/1

4:45 pm-12:07 am

1 stop8h 22m

Des Moines

Wed 7/8

7:04 am-1:04 pm

1 stop5h 00m

$257

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 8/6

12:39 pm-1:34 pm

1 stop25h 55m

Des Moines

Wed 8/12

2:19 pm-5:32 am

1 stop14h 13m

$261

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 7/22

2:00 pm-9:40 pm

1 stop8h 40m

Des Moines

Tue 7/28

5:20 am-2:15 pm

2 stops7h 55m

$262

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 7/30

12:39 pm-1:34 pm

1 stop25h 55m

Des Moines

Mon 8/3

2:19 pm-5:32 am

1 stop14h 13m

$280

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 6/10

10:32 pm-9:27 pm

1 stop23h 55m

Des Moines

Sun 6/14

5:02 pm-11:49 am

2 stops17h 47m

$295

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 8/6

5:15 am-11:25 am

1 stop7h 10m

Des Moines

Wed 8/12

6:10 am-2:55 pm

2 stops7h 45m

$299

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 8/6

11:30 am-10:10 pm

2 stops11h 40m

Des Moines

Wed 8/12

6:10 am-2:55 pm

2 stops7h 45m

$310

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 7/30

7:05 am-9:27 pm

2 stops15h 22m

Des Moines

Mon 8/3

4:40 pm-8:08 am

1 stop14h 28m

$321

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Tampa to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Tampa and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then November is your next best option. Flight prices from Tampa to Des Moines during November average around $310.

How have Tampa to Des Moines flight prices changed over time?

As of May 2026, prices for Tampa to Des Moines flights are approximately 66% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Des Moines

Fastest flight time

5h 34m

Direct flights

None
The fastest flight from Tampa to Des Moines takes 5h 34m
There are no direct flights from Tampa to Des Moines. There are no popular flight routes from Tampa to Des Moines.
Search flight deals

Frequently asked questions about flying from Tampa to Des Moines

  • How far is Tampa to Des Moines by plane?

    The distance between Tampa and Des Moines is about 1132.4 mi. Typically, this will take 5h 34m by plane in normal conditions.

  • When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?

    Prices for flights from Tampa Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?

  • How old do you have to be to fly from Tampa Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Tampa to Des Moines?

Best airlines flying from Tampa to Des Moines

Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $237Free CancellationRating
7.9
8,449 reviews
Search Delta flights
American AirlinesPriceFrom $250Free CancellationRating
7.1
11,644 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Urbandale
Johnston
Newton
Osceola
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Des Moines for you.

Can I find flights from Tampa to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Tampa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Tampa to Des Moines?

Once you have performed a search for Tampa to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tampa to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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