What is the cheapest airline that flies from Tampa to Des Moines?

Frontier, United Airlines, and American Airlines are the most popular carriers operating from Tampa to Des Moines

What airlines fly to Des Moines?

Allegiant Air, Delta and American Airlines are the top three most popular airlines that fly to Des Moines from Tampa according to our data. Allegiant Air is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 5 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?

Prices for flights from Tampa Airport to Des Moines Airport are updated daily.

How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?

As of September 2025, there are 4 operators available to choose from for flights from Tampa Airport to Des Moines Airport.

How old do you have to be to fly from Tampa Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$85 Cheap Flights from Tampa to Des Moines in 2025/26

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Find the cheapest flights from Tampa to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

6:37 am - 1:52 pmTPA-DSM

8h 15m1 stop

2:37 pm - 9:42 pmDSM-TPA

30h 05m1 stop

$230Frontier

Find Deal

Wed, Oct 15 - Wed, Oct 22

5:23 pm - 10:28 pmTPA-DSM

6h 05m1 stop

8:00 am - 7:03 pmDSM-TPA

10h 03m2 stops

$262United Airlines

Find Deal

Wed, Oct 15 - Wed, Oct 22

9:24 am - 2:56 pmTPA-DSM

6h 32m1 stop

2:19 pm - 9:46 pmDSM-TPA

6h 27m1 stop

$267American Airlines

Find Deal

Tue, Nov 4 - Sat, Nov 15

6:15 am - 2:27 pmTPA-DSM

33h 12m2 stops

10:41 am - 7:08 amDSM-TPA

19h 27m1 stop

$274Multiple Airlines

Find Deal

Tue, Sep 30 - Sun, Oct 5

6:55 am - 11:00 amTPA-DSM

5h 05m1 stop

6:15 pm - 11:25 pmDSM-TPA

4h 10m1 stop

$277Southwest

Find Deal

Thu, Nov 6 - Mon, Nov 10

7:20 am - 2:27 pmTPA-DSM

32h 07m1 stop

10:41 am - 7:08 amDSM-TPA

19h 27m1 stop

$282Multiple Airlines

Find Deal

Tue, Sep 30 - Sun, Oct 5

7:50 pm - 11:35 pmTPA-DSM

4h 45m1 stop

5:45 am - 7:25 pmDSM-TPA

12h 40m2 stops

$288Southwest

Find Deal

Thu, Nov 6 - Mon, Nov 10

1:04 pm - 5:02 pmTPA-DSM

4h 58m1 stop

6:22 pm - 12:19 amDSM-TPA

4h 57m1 stop

$317American Airlines

Find Deal

Fri, Oct 24 - Sun, Oct 26

3:56 pm - 8:35 pmTPA-DSM

5h 39m1 stop

6:05 am - 12:54 pmDSM-TPA

5h 49m1 stop

$348Delta

Find Deal

Fri, Oct 10 - Mon, Oct 13

3:56 pm - 8:35 pmTPA-DSM

5h 39m1 stop

6:39 pm - 12:17 amDSM-TPA

4h 38m1 stop

$890Delta

Find Deal

Wed, Oct 15 - Fri, Oct 17

American Airlines flights from Tampa to Des Moines

Our best American Airlines deals on Tampa to Des Moines flight tickets

American Airlines

Nov 4

TPA9:24 amTampa

6h 32m

1 stop

DSM2:56 pmDes Moines

Nov 15

DSM2:19 pmDes Moines

6h 27m

1 stop

TPA9:46 pmTampa

$267

Find similar

American Airlines

Oct 24

TPA1:04 pmTampa

4h 58m

1 stop

DSM5:02 pmDes Moines

Oct 26

DSM6:22 pmDes Moines

4h 57m

1 stop

TPA12:19 amTampa

$317

Find similar

American Airlines

Nov 4

TPA1:58 pmTampa

5h 12m

1 stop

DSM6:10 pmDes Moines

Nov 15

DSM4:02 pmDes Moines

7h 10m

2 stops

TPA12:12 amTampa

$322

Find similar

Frontier flights from Tampa to Des Moines

Our best Frontier deals on Tampa to Des Moines flight tickets

Frontier

Oct 15

TPA6:37 amTampa

8h 15m

1 stop

DSM1:52 pmDes Moines

Oct 22

DSM2:37 pmDes Moines

30h 05m

1 stop

TPA9:42 pmTampa

$230

Find similar

Frontier

Oct 10

TPA6:37 amTampa

8h 15m

1 stop

DSM1:52 pmDes Moines

Oct 17

DSM2:37 pmDes Moines

18h 33m

2 stops

TPA10:10 amTampa

$271

Find similar

Frontier

Sep 22

TPA6:37 amTampa

8h 03m

1 stop

DSM1:40 pmDes Moines

Sep 26

DSM2:25 pmDes Moines

14h 06m

1 stop

TPA5:31 amTampa

$311

Find similar

Fly from

Fly to

Route

Depart

Return

Price

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 10/15

6:37 am-1:52 pm

1 stop8h 15m

Des Moines

Wed 10/22

2:37 pm-9:42 pm

1 stop30h 05m

$230

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 10/15

5:23 pm-10:28 pm

1 stop6h 05m

Des Moines

Wed 10/22

8:00 am-7:03 pm

2 stops10h 03m

$262

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 11/4

9:24 am-2:56 pm

1 stop6h 32m

Des Moines

Sat 11/15

2:19 pm-9:46 pm

1 stop6h 27m

$267

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 9/30

6:15 am-2:27 pm

2 stops33h 12m

Des Moines

Sun 10/5

10:41 am-7:08 am

1 stop19h 27m

$274

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 11/6

6:55 am-11:00 am

1 stop5h 05m

Des Moines

Mon 11/10

6:15 pm-11:25 pm

1 stop4h 10m

$277

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 9/30

7:20 am-2:27 pm

1 stop32h 07m

Des Moines

Sun 10/5

10:41 am-7:08 am

1 stop19h 27m

$282

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 11/6

7:50 pm-11:35 pm

1 stop4h 45m

Des Moines

Mon 11/10

5:45 am-7:25 pm

2 stops12h 40m

$288

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 10/24

1:04 pm-5:02 pm

1 stop4h 58m

Des Moines

Sun 10/26

6:22 pm-12:19 am

1 stop4h 57m

$317

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 10/10

3:56 pm-8:35 pm

1 stop5h 39m

Des Moines

Mon 10/13

6:05 am-12:54 pm

1 stop5h 49m

$348

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 10/15

3:56 pm-8:35 pm

1 stop5h 39m

Des Moines

Fri 10/17

6:39 pm-12:17 am

1 stop4h 38m

$890

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Tampa to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in July, then September is your next best option. Flight prices from Tampa to Des Moines during September average around $316.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Tampa to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $341. Flights from Tampa to Des Moines on a Monday will generally be more expensive and average around $676. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Tampa to Des Moines in the evening for as low as $343. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $460. Of course, these prices can vary depending on the time of year and what airport you fly to.

How have Tampa to Des Moines flight prices changed over time?

As of September 2025, prices for Tampa to Des Moines flights are approximately 5% cheaper when compared to flights at the same time last year.

When to book flights from Tampa to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Des Moines

Direct flights	None

There are no direct flights from Tampa to Des Moines. There are no popular flight routes from Tampa to Des Moines.

Search flight deals

How far is Tampa to Des Moines by plane?
The distance between Tampa and Des Moines is about 1132.4 mi. Typically, this will take 4h 25m by plane in normal conditions.
When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?
Prices for flights from Tampa Airport to Des Moines Airport are updated daily.
How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?
As of September 2025, there are 4 operators available to choose from for flights from Tampa Airport to Des Moines Airport.
How old do you have to be to fly from Tampa Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Tampa to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Tampa to Des Moines is Delta (40% of total bookings). The next most popular airlines are American Airlines (28%), Southwest (21%), and Frontier (11%).

Best airlines flying from Tampa to Des Moines

Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $86	Free Cancellation	Rating 5.8 3,173 reviews	Search Frontier flights
American Airlines	PriceFrom $250	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Southwest	PriceFrom $284	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights
Delta	PriceFrom $286	Free Cancellation	Rating 7.9 7,961 reviews	Search Delta flights

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Pella

Newton

Osceola

Johnston

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Des Moines for you.

Can I find flights from Tampa to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Tampa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Tampa to Des Moines?

Once you have performed a search for Tampa to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tampa to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.