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Cheap flights from Tampa to Des Moines from $119

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Tampa to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:49 pm - 5:02 pmTPA  Tampa-DSM Des Moines
19h 13m1 stop Fort Lauderdale
Multiple Airlines Logo
8:00 am - 11:49 amDSM  Des Moines-TPA Tampa
50h 49m2 stops Philadelphia Atlanta Hartsfield-Jackson
$215Multiple Airlines
Wed, Oct 21 - Sun, Nov 1
American Airlines Logo
7:22 pm - 12:26 amTPA  Tampa-DSM Des Moines
6h 04m1 stop Chicago O'Hare Intl
American Airlines Logo
11:09 am - 5:41 pmDSM  Des Moines-TPA Tampa
5h 32m1 stop Charlotte Douglas
$237American Airlines
Wed, Nov 4 - Mon, Nov 9
Delta Logo
5:10 am - 10:44 amTPA  Tampa-DSM Des Moines
6h 34m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:52 pm - 12:25 amDSM  Des Moines-TPA Tampa
4h 33m1 stop Atlanta Hartsfield-Jackson
$237Delta
Wed, Nov 11 - Mon, Nov 16
Delta Logo
4:38 pm - 10:33 pmTPA  Tampa-DSM Des Moines
6h 55m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:54 pm - 12:18 amDSM  Des Moines-TPA Tampa
4h 24m1 stop Atlanta Hartsfield-Jackson
$237Delta
Tue, Oct 13 - Mon, Oct 19
Southwest Logo
7:20 am - 11:30 amTPA  Tampa-DSM Des Moines
5h 10m1 stop Chicago Midway
Southwest Logo
5:10 am - 12:10 pmDSM  Des Moines-TPA Tampa
6h 00m1 stop Chicago Midway
$237Southwest
Wed, Oct 14 - Mon, Oct 19
Southwest Logo
7:20 am - 11:30 amTPA  Tampa-DSM Des Moines
5h 10m1 stop Chicago Midway
Southwest Logo
5:10 am - 12:10 pmDSM  Des Moines-TPA Tampa
6h 00m1 stop Chicago Midway
$237Southwest
Wed, Oct 14 - Mon, Oct 19
American Airlines Logo
7:34 am - 12:23 pmTPA  Tampa-DSM Des Moines
5h 49m1 stop Charlotte Douglas
American Airlines Logo
4:12 pm - 10:30 pmDSM  Des Moines-TPA Tampa
5h 18m1 stop Dallas/Fort Worth
$237American Airlines
Tue, Oct 20 - Tue, Oct 27
United Airlines Logo
5:18 pm - 10:15 pmTPA  Tampa-DSM Des Moines
5h 57m1 stop Houston George Bush Intcntl
United Airlines Logo
1:26 pm - 11:32 pmDSM  Des Moines-TPA Tampa
9h 06m2 stops Chicago O'Hare Intl Newark
$283United Airlines
Tue, Oct 13 - Sat, Oct 17
American Airlines Logo
3:14 pm - 11:05 pmTPA  Tampa-DSM Des Moines
8h 51m1 stop Dallas/Fort Worth
American Airlines Logo
11:09 am - 5:41 pmDSM  Des Moines-TPA Tampa
5h 32m1 stop Charlotte Douglas
$301American Airlines
Wed, Nov 4 - Mon, Nov 9
United Airlines Logo
8:00 am - 4:07 pmTPA  Tampa-DSM Des Moines
9h 07m1 stop Denver Intl
United Airlines Logo
8:00 am - 6:02 pmDSM  Des Moines-TPA Tampa
9h 02m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$352United Airlines
Wed, Nov 4 - Mon, Nov 9

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American Airlines flights from Tampa to Des Moines

Our best American Airlines deals on Tampa to Des Moines flight tickets
American Airlines
Nov 4
TPA7:22 pmTampa
6h 04m
1 stop
DSM12:26 amDes Moines
Nov 9
DSM11:09 amDes Moines
5h 32m
1 stop
TPA5:41 pmTampa
$237
American Airlines
Nov 5
TPA7:22 pmTampa
6h 04m
1 stop
DSM12:26 amDes Moines
Nov 8
DSM6:00 amDes Moines
7h 24m
1 stop
TPA2:24 pmTampa
$337
American Airlines
Oct 17
TPA7:22 pmTampa
5h 52m
1 stop
DSM12:14 amDes Moines
Oct 18
DSM6:05 amDes Moines
6h 58m
1 stop
TPA2:03 pmTampa
$364

Southwest flights from Tampa to Des Moines

Our best Southwest deals on Tampa to Des Moines flight tickets
Southwest
Oct 14
TPA7:20 amTampa
5h 10m
1 stop
DSM11:30 amDes Moines
Oct 19
DSM5:10 amDes Moines
5h 50m
2 stops
TPA12:00 pmTampa
$238
Southwest
Oct 20
TPA7:20 amTampa
5h 10m
1 stop
DSM11:30 amDes Moines
Oct 27
DSM5:35 amDes Moines
10h 10m
2 stops
TPA4:45 pmTampa
$242
Southwest
Oct 14
TPA4:00 pmTampa
7h 00m
2 stops
DSM10:00 pmDes Moines
Oct 19
DSM5:10 amDes Moines
5h 50m
2 stops
TPA12:00 pmTampa
$243

momondo Fare Finder

 
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 10/21

10:49 pm-5:02 pm

1 stop19h 13m

Des Moines

Sun 11/1

8:00 am-11:49 am

2 stops50h 49m

$215

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 11/4

7:22 pm-12:26 am

1 stop6h 04m

Des Moines

Mon 11/9

11:09 am-5:41 pm

1 stop5h 32m

$237
Quickest round-trip

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 11/11

5:10 am-10:44 am

1 stop6h 34m

Des Moines

Mon 11/16

6:52 pm-12:25 am

1 stop4h 33m

$237

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Tue 10/13

4:38 pm-10:33 pm

1 stop6h 55m

Des Moines

Mon 10/19

6:54 pm-12:18 am

1 stop4h 24m

$237

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 10/14

7:20 am-11:30 am

1 stop5h 10m

Des Moines

Mon 10/19

5:10 am-12:10 pm

1 stop6h 00m

$237

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 10/14

7:20 am-11:30 am

1 stop5h 10m

Des Moines

Mon 10/19

5:10 am-12:10 pm

1 stop6h 00m

$237

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Tue 10/20

7:34 am-12:23 pm

1 stop5h 49m

Des Moines

Tue 10/27

4:12 pm-10:30 pm

1 stop5h 18m

$237

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Tue 10/13

5:18 pm-10:15 pm

1 stop5h 57m

Des Moines

Sat 10/17

1:26 pm-11:32 pm

2 stops9h 06m

$283

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 11/4

3:14 pm-11:05 pm

1 stop8h 51m

Des Moines

Mon 11/9

11:09 am-5:41 pm

1 stop5h 32m

$301

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 11/4

8:00 am-4:07 pm

1 stop9h 07m

Des Moines

Mon 11/9

8:00 am-6:02 pm

2 stops9h 02m

$352

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Tampa to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Tampa and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $656 to $739.
The lowest price recently found on this route was $215.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in August, then May is your next best option. Flight prices from Tampa to Des Moines during May average around $428.

How have Tampa to Des Moines flight prices changed over time?

As of September 2026, prices for Tampa to Des Moines flights are approximately 15% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Des Moines

Best Price Found

$119

Fastest flight time

5h 00m

Direct flights

None
The best one-way flight to Des Moines from Tampa in the past 72 hours is $119. The best round-trip flight deal from Tampa to Des Moines found on momondo in the last 72 hours is $215.
The fastest flight from Tampa to Des Moines takes 5h 00m
There are no direct flights from Tampa to Des Moines. There are no popular flight routes from Tampa to Des Moines.
Search flight deals

Frequently asked questions about flying from Tampa to Des Moines

  • How far is Tampa to Des Moines by plane?

    The distance between Tampa and Des Moines is about 1132.4 mi. Typically, this will take 5h 00m by plane in normal conditions.

  • When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?

    Prices for flights from Tampa Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?

  • How old do you have to be to fly from Tampa Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Tampa to Des Moines?

Best airlines flying from Tampa to Des Moines

Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $251Free CancellationRating
7.0
12,072 reviews
Search American Airlines flights
DeltaPriceFrom $256Free CancellationRating
7.8
8,590 reviews
Search Delta flights
United AirlinesPriceFrom $635Free CancellationRating
7.4
10,220 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Boone
Johnston
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Des Moines for you.

Can I find flights from Tampa to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Tampa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Tampa to Des Moines?

Once you have performed a search for Tampa to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tampa to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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