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Cheap flights from Tampa to Des Moines from $116

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Des Moines departing on 3/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Tampa to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:40 am - 1:09 pm
TPA
-
DSM
7h 29m
1 stop
Frontier Logo
2:04 pm - 5:32 am
DSM
-
TPA
14h 28m
1 stop
$233Frontier
Fri, Apr 24 - Mon, Apr 27
United Airlines Logo
4:50 pm - 11:17 pm
TPA
-
DSM
7h 27m
2 stops
United Airlines Logo
1:10 pm - 7:35 pm
DSM
-
TPA
5h 25m
1 stop
$279United Airlines
Tue, Apr 21 - Thu, Apr 23
United Airlines Logo
7:10 am - 2:24 pm
TPA
-
DSM
8h 14m
1 stop
United Airlines Logo
3:20 pm - 10:17 pm
DSM
-
TPA
5h 57m
1 stop
$284United Airlines
Wed, May 6 - Mon, May 18
United Airlines Logo
7:00 am - 4:15 pm
TPA
-
DSM
10h 15m
2 stops
United Airlines Logo
3:20 pm - 10:17 pm
DSM
-
TPA
5h 57m
1 stop
$289United Airlines
Wed, May 6 - Mon, May 18
Multiple Airlines Logo
8:14 am - 10:06 pm
TPA
-
DSM
14h 52m
1 stop
Multiple Airlines Logo
9:07 pm - 5:41 pm
DSM
-
TPA
19h 34m
2 stops
$298Multiple Airlines
Thu, Apr 9 - Mon, Apr 13
Multiple Airlines Logo
6:40 am - 1:09 pm
TPA
-
DSM
7h 29m
1 stop
Multiple Airlines Logo
8:30 am - 7:34 am
DSM
-
TPA
22h 04m
2 stops
$304Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
6:40 am - 1:09 pm
TPA
-
DSM
7h 29m
1 stop
Multiple Airlines Logo
8:30 am - 7:36 pm
DSM
-
TPA
10h 06m
1 stop
$306Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
6:40 am - 1:09 pm
TPA
-
DSM
7h 29m
1 stop
Multiple Airlines Logo
8:30 am - 7:34 am
DSM
-
TPA
22h 04m
2 stops
$309Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
6:40 am - 1:09 pm
TPA
-
DSM
7h 29m
1 stop
Multiple Airlines Logo
8:30 am - 9:05 am
DSM
-
TPA
23h 35m
1 stop
$311Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
10:44 pm - 3:50 pm
TPA
-
DSM
18h 06m
1 stop
Multiple Airlines Logo
4:40 pm - 8:08 am
DSM
-
TPA
14h 28m
1 stop
$314Multiple Airlines
Sun, Jul 26 - Mon, Aug 3

Frontier flights from Tampa to Des Moines

Our best Frontier deals on Tampa to Des Moines flight tickets
Frontier
Apr 24
TPA6:40 amTampa
7h 29m
1 stop
DSM1:09 pmDes Moines
Apr 27
DSM2:04 pmDes Moines
14h 28m
1 stop
TPA5:32 amTampa
$233
Frontier
Mar 23
TPA6:00 amTampa
14h 16m
1 stop
DSM7:16 pmDes Moines
Mar 30
DSM8:21 pmDes Moines
8h 39m
1 stop
TPA6:00 amTampa
$295
Frontier
Mar 23
TPA6:00 amTampa
14h 16m
1 stop
DSM7:16 pmDes Moines
Mar 30
DSM8:21 pmDes Moines
8h 39m
1 stop
TPA6:00 amTampa
$315

United Airlines flights from Tampa to Des Moines

Our best United Airlines deals on Tampa to Des Moines flight tickets
United Airlines
Apr 21
TPA4:50 pmTampa
7h 27m
2 stops
DSM11:17 pmDes Moines
Apr 23
DSM1:10 pmDes Moines
5h 25m
1 stop
TPA7:35 pmTampa
$279
United Airlines
May 6
TPA7:10 amTampa
8h 14m
1 stop
DSM2:24 pmDes Moines
May 18
DSM3:20 pmDes Moines
5h 57m
1 stop
TPA10:17 pmTampa
$284
United Airlines
May 6
TPA7:00 amTampa
10h 15m
2 stops
DSM4:15 pmDes Moines
May 18
DSM3:20 pmDes Moines
5h 57m
1 stop
TPA10:17 pmTampa
$289

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 4/24

6:40 am-1:09 pm

1 stop7h 29m

Des Moines

Mon 4/27

2:04 pm-5:32 am

1 stop14h 28m

$233
Quickest round-trip

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 4/21

4:50 pm-11:17 pm

2 stops7h 27m

Des Moines

Thu 4/23

1:10 pm-7:35 pm

1 stop5h 25m

$279

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 5/6

7:10 am-2:24 pm

1 stop8h 14m

Des Moines

Mon 5/18

3:20 pm-10:17 pm

1 stop5h 57m

$284

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 5/6

7:00 am-4:15 pm

2 stops10h 15m

Des Moines

Mon 5/18

3:20 pm-10:17 pm

1 stop5h 57m

$289

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 4/9

8:14 am-10:06 pm

1 stop14h 52m

Des Moines

Mon 4/13

9:07 pm-5:41 pm

2 stops19h 34m

$298

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 4/17

6:40 am-1:09 pm

1 stop7h 29m

Des Moines

Sun 4/19

8:30 am-7:34 am

2 stops22h 04m

$304

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 4/17

6:40 am-1:09 pm

1 stop7h 29m

Des Moines

Sun 4/19

8:30 am-7:36 pm

1 stop10h 06m

$306

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 4/17

6:40 am-1:09 pm

1 stop7h 29m

Des Moines

Sun 4/19

8:30 am-7:34 am

2 stops22h 04m

$309

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 4/17

6:40 am-1:09 pm

1 stop7h 29m

Des Moines

Sun 4/19

8:30 am-9:05 am

1 stop23h 35m

$311

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Sun 7/26

10:44 pm-3:50 pm

1 stop18h 06m

Des Moines

Mon 8/3

4:40 pm-8:08 am

1 stop14h 28m

$314

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Tampa to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then November is your next best option. Flight prices from Tampa to Des Moines during November average around $310.

How have Tampa to Des Moines flight prices changed over time?

As of March 2026, prices for Tampa to Des Moines flights are approximately 21% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Des Moines

Fastest flight time

4h 44m

Direct flights

None
The fastest flight from Tampa to Des Moines takes 4h 44m
There are no direct flights from Tampa to Des Moines. There are no popular flight routes from Tampa to Des Moines.
Search flight deals

  • How far is Tampa to Des Moines by plane?

    The distance between Tampa and Des Moines is about 1132.4 mi. Typically, this will take 4h 44m by plane in normal conditions.

  • When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?

    Prices for flights from Tampa Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?

  • How old do you have to be to fly from Tampa Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Tampa to Des Moines?

Best airlines flying from Tampa to Des Moines

Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $237Free CancellationRating
7.9
8,293 reviews
Search Delta flights
American AirlinesPriceFrom $250Free CancellationRating
7.1
11,472 reviews
Search American Airlines flights
SouthwestPriceFrom $252Free CancellationRating
8.0
4,318 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Des Moines for you.

Can I find flights from Tampa to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Tampa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Tampa to Des Moines?

Once you have performed a search for Tampa to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tampa to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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