Cheap flights from Tampa to Des Moines from $100
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Des Moines departing on 11/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Find the cheapest flights from Tampa to Des Moines
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Southwest flights from Tampa to Des Moines
Our best Southwest deals on Tampa to Des Moines flight tickets
Delta flights from Tampa to Des Moines
Our best Delta deals on Tampa to Des Moines flight tickets
momondo Fare Finder
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 11/4
10:49 pm-3:25 pm
1 stop17h 36m
Des Moines
Thu 11/12
4:15 pm-7:10 am
1 stop13h 55m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Fri 11/6
6:15 am-7:35 pm
1 stop14h 20m
Des Moines
Mon 11/9
8:30 pm-12:27 am
1 stop26h 57m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 11/4
7:51 am-1:28 pm
1 stop6h 37m
Des Moines
Mon 11/9
3:31 pm-11:37 pm
1 stop7h 06m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Tue 11/10
6:20 pm-10:35 pm
1 stop5h 15m
Des Moines
Wed 11/11
2:48 pm-11:07 pm
1 stop7h 19m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Tue 11/10
12:30 pm-5:28 pm
1 stop5h 58m
Des Moines
Wed 11/11
6:05 am-3:41 pm
2 stops8h 36m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Tue 11/10
6:00 am-2:15 pm
2 stops9h 15m
Des Moines
Wed 11/11
6:00 am-1:10 pm
2 stops6h 10m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Mon 11/9
5:35 am-10:10 am
1 stop5h 35m
Des Moines
Wed 11/11
3:31 pm-9:58 pm
1 stop5h 27m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 11/4
7:00 am-10:42 am
1 stop4h 42m
Des Moines
Mon 11/9
2:59 pm-10:15 pm
1 stop6h 16m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 11/4
7:51 am-1:28 pm
1 stop6h 37m
Des Moines
Mon 11/9
3:31 pm-11:37 pm
1 stop7h 06m
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Fri 11/6
1:55 pm-9:55 pm
2 stops9h 00m
Des Moines
Mon 11/9
3:01 pm-9:39 pm
1 stop5h 38m
See travel insights to Des Moines from
How to get the cheapest flight ticket from Tampa to Des Moines
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Des Moines?
If you’re not able to fly to Des Moines in November, then August is your next best option. Flight prices from Tampa to Des Moines during August average around $426.
How have Tampa to Des Moines flight prices changed over time?
As of October 2026, prices for Tampa to Des Moines flights are approximately 150% more expensive when compared to flights at the same time last year.
What is the cheapest airline that flies from Tampa to Des Moines?
Frontier is the most popular carrier operating from Tampa to Des Moines
What airlines fly to Des Moines?
Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Des Moines from Tampa according to our data. Allegiant Air is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 5 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.
When to book flights from Tampa to Des Moines
Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Tampa to Des Moines
Frequently asked questions about flying from Tampa to Des Moines
How far is Tampa to Des Moines by plane?
The distance between Tampa and Des Moines is about 1132.4 mi. Typically, this will take 5h 05m by plane in normal conditions.
When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?
Prices for flights from Tampa Airport to Des Moines Airport are updated daily.
How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?
As of October 2026, there are 3 operators available to choose from for flights from Tampa Airport to Des Moines Airport.
How old do you have to be to fly from Tampa Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Tampa to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Tampa to Des Moines is American Airlines (47% of total bookings). The next most popular airlines are Delta (32%) and United Airlines (22%).
Best airlines flying from Tampa to Des Moines
Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $251 | Free Cancellation | Rating 7.0 12,146 reviews | |||
| PriceFrom $256 | Free Cancellation | Rating 7.8 8,646 reviews | |||
| PriceFrom $635 | Free Cancellation | Rating 7.4 10,322 reviews |
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Tampa to Des Moines?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Des Moines for you.
Can I find flights from Tampa to Des Moines with flexible booking policies on momondo?
momondo does allow users to show only those flights to Des Moines from Tampa which offer a flexible booking policy as well as other useful filters and features.
How can momondo help me find flights from Tampa to Des Moines?
Once you have performed a search for Tampa to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.
I’m not ready to book a flight from Tampa to Des Moines right now. Can momondo alert me if prices change?
Yes. momondo can track prices for Tampa to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.