Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Tampa to Des Moines from $106

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Des Moines departing on 7/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Tampa to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:30 am - 1:34 pm
TPA
-
DSM
7h 04m
1 stop
Delta Logo
2:25 pm - 9:30 pm
DSM
-
TPA
6h 05m
1 stop
$237Delta
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
4:40 pm - 10:50 pm
TPA
-
DSM
7h 10m
2 stops
Southwest Logo
3:45 pm - 11:55 pm
DSM
-
TPA
7h 10m
1 stop
$242Southwest
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
4:40 pm - 10:50 pm
TPA
-
DSM
7h 10m
2 stops
Southwest Logo
5:20 am - 2:15 pm
DSM
-
TPA
7h 55m
2 stops
$247Southwest
Tue, Jul 21 - Tue, Jul 28
Multiple Airlines Logo
7:00 am - 11:07 pm
TPA
-
DSM
17h 07m
2 stops
Multiple Airlines Logo
4:40 pm - 8:08 am
DSM
-
TPA
14h 28m
1 stop
$268Multiple Airlines
Thu, Jul 23 - Mon, Jul 27
Delta Logo
5:15 am - 10:43 am
TPA
-
DSM
6h 28m
1 stop
Delta Logo
6:35 pm - 12:30 am
DSM
-
TPA
4h 55m
1 stop
$273Delta
Wed, Aug 12 - Wed, Aug 26
American Airlines Logo
4:51 pm - 12:09 am
TPA
-
DSM
8h 18m
1 stop
American Airlines Logo
5:10 pm - 11:21 pm
DSM
-
TPA
5h 11m
1 stop
$275American Airlines
Wed, Jul 29 - Wed, Aug 5
Delta Logo
12:36 pm - 6:09 pm
TPA
-
DSM
6h 33m
1 stop
Delta Logo
3:30 pm - 10:34 pm
DSM
-
TPA
6h 04m
1 stop
$288Delta
Wed, Nov 4 - Mon, Nov 9
Southwest Logo
5:15 am - 11:25 am
TPA
-
DSM
7h 10m
1 stop
Southwest Logo
5:35 am - 1:40 pm
DSM
-
TPA
7h 05m
2 stops
$293Southwest
Thu, Sep 24 - Wed, Oct 7
Southwest Logo
2:10 pm - 10:10 pm
TPA
-
DSM
9h 00m
2 stops
Southwest Logo
5:35 am - 1:40 pm
DSM
-
TPA
7h 05m
2 stops
$298Southwest
Thu, Sep 24 - Wed, Oct 7
Multiple Airlines Logo
7:00 am - 11:07 pm
TPA
-
DSM
17h 07m
2 stops
Multiple Airlines Logo
3:37 pm - 9:25 pm
DSM
-
TPA
28h 48m
1 stop
$303Multiple Airlines
Thu, Jul 16 - Thu, Jul 30

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Frontier flights from Tampa to Des Moines

Our best Frontier deals on Tampa to Des Moines flight tickets
Frontier
Jul 30
TPA8:20 pmTampa
18h 14m
1 stop
DSM1:34 pmDes Moines
Aug 3
DSM2:19 pmDes Moines
14h 13m
1 stop
TPA5:32 amTampa
$348
Frontier
Jul 5
TPA8:20 pmTampa
18h 14m
1 stop
DSM1:34 pmDes Moines
Jul 10
DSM2:19 pmDes Moines
14h 13m
1 stop
TPA5:32 amTampa
$565

Southwest flights from Tampa to Des Moines

Our best Southwest deals on Tampa to Des Moines flight tickets
Southwest
Jul 21
TPA4:40 pmTampa
7h 10m
2 stops
DSM10:50 pmDes Moines
Jul 28
DSM3:45 pmDes Moines
7h 10m
1 stop
TPA11:55 pmTampa
$242
Southwest
Jul 21
TPA4:40 pmTampa
7h 10m
2 stops
DSM10:50 pmDes Moines
Jul 28
DSM5:20 amDes Moines
7h 55m
2 stops
TPA2:15 pmTampa
$247
Southwest
Sep 24
TPA5:15 amTampa
7h 10m
1 stop
DSM11:25 amDes Moines
Oct 7
DSM5:35 amDes Moines
7h 05m
2 stops
TPA1:40 pmTampa
$293

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 7/21

7:30 am-1:34 pm

1 stop7h 04m

Des Moines

Tue 7/28

2:25 pm-9:30 pm

1 stop6h 05m

$237

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 7/21

4:40 pm-10:50 pm

2 stops7h 10m

Des Moines

Tue 7/28

3:45 pm-11:55 pm

1 stop7h 10m

$242

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 7/21

4:40 pm-10:50 pm

2 stops7h 10m

Des Moines

Tue 7/28

5:20 am-2:15 pm

2 stops7h 55m

$247

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 7/23

7:00 am-11:07 pm

2 stops17h 07m

Des Moines

Mon 7/27

4:40 pm-8:08 am

1 stop14h 28m

$268
Quickest round-trip

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 8/12

5:15 am-10:43 am

1 stop6h 28m

Des Moines

Wed 8/26

6:35 pm-12:30 am

1 stop4h 55m

$273

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 7/29

4:51 pm-12:09 am

1 stop8h 18m

Des Moines

Wed 8/5

5:10 pm-11:21 pm

1 stop5h 11m

$275

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 11/4

12:36 pm-6:09 pm

1 stop6h 33m

Des Moines

Mon 11/9

3:30 pm-10:34 pm

1 stop6h 04m

$288

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 9/24

5:15 am-11:25 am

1 stop7h 10m

Des Moines

Wed 10/7

5:35 am-1:40 pm

2 stops7h 05m

$293

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 9/24

2:10 pm-10:10 pm

2 stops9h 00m

Des Moines

Wed 10/7

5:35 am-1:40 pm

2 stops7h 05m

$298

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 7/16

7:00 am-11:07 pm

2 stops17h 07m

Des Moines

Thu 7/30

3:37 pm-9:25 pm

1 stop28h 48m

$303

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Tampa to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Tampa and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then November is your next best option. Flight prices from Tampa to Des Moines during November average around $353.

How have Tampa to Des Moines flight prices changed over time?

As of July 2026, prices for Tampa to Des Moines flights are approximately 20% cheaper when compared to flights at the same time last year.

When to book flights from Tampa to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Des Moines

Fastest flight time

4h 58m

Direct flights

None
The fastest flight from Tampa to Des Moines takes 4h 58m
There are no direct flights from Tampa to Des Moines. There are no popular flight routes from Tampa to Des Moines.
Search flight deals

Frequently asked questions about flying from Tampa to Des Moines

  • How far is Tampa to Des Moines by plane?

    The distance between Tampa and Des Moines is about 1132.4 mi. Typically, this will take 4h 58m by plane in normal conditions.

  • When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?

    Prices for flights from Tampa Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?

  • How old do you have to be to fly from Tampa Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Tampa to Des Moines?

Best airlines flying from Tampa to Des Moines

Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $222Free CancellationRating
7.8
8,453 reviews
Search Delta flights
American AirlinesPriceFrom $250Free CancellationRating
7.1
11,764 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Des Moines for you.

Can I find flights from Tampa to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Tampa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Tampa to Des Moines?

Once you have performed a search for Tampa to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tampa to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 8/2
Sun 8/9
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States