What is the cheapest airline that flies from Tampa to Des Moines?

Delta, Southwest, and United Airlines are the most popular carriers operating from Tampa to Des Moines

What airlines fly to Des Moines?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Des Moines from Tampa according to our data. Allegiant Air is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 5 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?

Prices for flights from Tampa Airport to Des Moines Airport are updated daily.

How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?

As of October 2026, there are 3 operators available to choose from for flights from Tampa Airport to Des Moines Airport.

How old do you have to be to fly from Tampa Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$111 Cheap Flights from Tampa to Des Moines in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Tampa to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:11 pm - 3:25 pmTPA Tampa-DSM Des Moines

25h 14m1 stop Fort Lauderdale

12:25 pm - 7:10 amDSM Des Moines-TPA Tampa

17h 45m1 stop Fort Lauderdale

$265Multiple Airlines

Wed, Nov 4 - Sun, Nov 8

5:20 am - 10:49 amTPA Tampa-DSM Des Moines

6h 29m1 stop Atlanta Hartsfield-Jackson

6:43 pm - 12:25 amDSM Des Moines-TPA Tampa

4h 42m1 stop Atlanta Hartsfield-Jackson

$293Delta

Sat, Dec 19 - Sat, Dec 19

5:10 am - 10:49 amTPA Tampa-DSM Des Moines

6h 39m1 stop Atlanta Hartsfield-Jackson

6:43 pm - 12:25 amDSM Des Moines-TPA Tampa

4h 42m1 stop Atlanta Hartsfield-Jackson

$293Delta

Thu, Dec 17 - Sat, Dec 19

6:20 am - 10:49 amTPA Tampa-DSM Des Moines

5h 29m1 stop Atlanta Hartsfield-Jackson

6:43 pm - 12:25 amDSM Des Moines-TPA Tampa

4h 42m1 stop Atlanta Hartsfield-Jackson

$293Delta

Wed, Dec 16 - Sat, Dec 19

7:08 am - 3:25 pmTPA Tampa-DSM Des Moines

33h 17m2 stops Atlanta Hartsfield-Jackson Fort Lauderdale

12:25 pm - 7:10 amDSM Des Moines-TPA Tampa

17h 45m1 stop Fort Lauderdale

$300Multiple Airlines

Wed, Nov 4 - Sun, Nov 8

6:10 pm - 11:35 pmTPA Tampa-DSM Des Moines

6h 25m1 stop Chicago Midway

7:15 pm - 1:00 amDSM Des Moines-TPA Tampa

4h 45m1 stop Chicago Midway

$307Southwest

Fri, Dec 18 - Mon, Dec 21

6:34 pm - 11:26 pmTPA Tampa-DSM Des Moines

5h 52m1 stop Charlotte Douglas

1:58 pm - 10:42 pmDSM Des Moines-TPA Tampa

7h 44m1 stop Chicago O'Hare Intl

$403American Airlines

Mon, Nov 16 - Wed, Nov 18

5:08 pm - 11:05 pmTPA Tampa-DSM Des Moines

6h 57m1 stop Dallas/Fort Worth

3:31 pm - 9:58 pmDSM Des Moines-TPA Tampa

5h 27m1 stop Dallas/Fort Worth

$428American Airlines

Wed, Nov 4 - Mon, Nov 9

9:10 am - 9:25 pmTPA Tampa-DSM Des Moines

13h 15m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

5:00 am - 12:44 pmDSM Des Moines-TPA Tampa

6h 44m1 stop Chicago O'Hare Intl

$440United Airlines

Wed, Dec 16 - Mon, Dec 21

9:10 am - 7:19 pmTPA Tampa-DSM Des Moines

11h 09m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

5:30 am - 1:12 pmDSM Des Moines-TPA Tampa

6h 42m1 stop Denver Intl

$440United Airlines

Wed, Dec 16 - Tue, Dec 22

Cheap last minute flights

Enter your travel dates to find the best prices.

6:15 am - 7:30 pmTPA Tampa-DSM Des Moines

14h 15m1 stop Denver Intl

8:30 pm - 5:34 pmDSM Des Moines-TPA Tampa

20h 04m1 stop Denver Intl

$420Frontier

Mon, Oct 26 - Fri, Oct 30

9:21 pm - 2:42 pmTPA Tampa-DSM Des Moines

18h 21m1 stop Philadelphia

5:52 pm - 7:10 amDSM Des Moines-TPA Tampa

12h 18m1 stop Fort Lauderdale

$446Multiple Airlines

Wed, Oct 28 - Thu, Oct 29

9:21 pm - 2:42 pmTPA Tampa-DSM Des Moines

18h 21m1 stop Philadelphia

5:52 pm - 5:22 pmDSM Des Moines-TPA Tampa

22h 30m2 stops Fort Lauderdale Atlanta Hartsfield-Jackson

$486Multiple Airlines

Wed, Oct 28 - Thu, Oct 29

12:31 pm - 5:47 pmTPA Tampa-DSM Des Moines

6h 16m1 stop Fort Lauderdale

8:30 am - 12:27 amDSM Des Moines-TPA Tampa

14h 57m2 stops Nashville Intl Denver Intl

$780Multiple Airlines

Sun, Oct 25 - Mon, Oct 26

8:00 am - 4:07 pmTPA Tampa-DSM Des Moines

9h 07m1 stop Denver Intl

6:05 am - 6:02 pmDSM Des Moines-TPA Tampa

10h 57m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

$1,007United Airlines

Mon, Oct 26 - Fri, Oct 30

12:15 pm - 10:00 pmTPA Tampa-DSM Des Moines

10h 45m2 stops Baltimore/Washington Chicago Midway

5:10 am - 12:00 pmDSM Des Moines-TPA Tampa

5h 50m2 stops Chicago Midway Atlanta Hartsfield-Jackson

$1,008Southwest

Wed, Oct 28 - Thu, Oct 29

9:15 am - 5:27 pmTPA Tampa-DSM Des Moines

9h 12m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

6:05 am - 6:02 pmDSM Des Moines-TPA Tampa

10h 57m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

$1,012United Airlines

Mon, Oct 26 - Fri, Oct 30

6:35 pm - 10:59 pmTPA Tampa-DSM Des Moines

5h 24m1 stop Chicago O'Hare Intl

9:00 am - 7:28 pmDSM Des Moines-TPA Tampa

9h 28m1 stop Denver Intl

$1,072United Airlines

Sun, Oct 25 - Mon, Oct 26

12:30 pm - 7:16 pmTPA Tampa-DSM Des Moines

7h 46m1 stop Chicago O'Hare Intl

3:24 pm - 9:43 pmDSM Des Moines-TPA Tampa

5h 19m1 stop Chicago O'Hare Intl

$1,077United Airlines

Sun, Oct 25 - Tue, Oct 27

4:26 pm - 10:59 pmTPA Tampa-DSM Des Moines

7h 33m1 stop Chicago O'Hare Intl

11:22 am - 10:09 pmDSM Des Moines-TPA Tampa

9h 47m2 stops Chicago O'Hare Intl Newark

$1,082United Airlines

Sun, Oct 25 - Tue, Oct 27

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Southwest flights from Tampa to Des Moines

Our best Southwest deals on Tampa to Des Moines flight tickets

Southwest

Dec 18

TPA6:10 pmTampa

6h 25m

1 stop

DSM11:35 pmDes Moines

Dec 21

DSM7:15 pmDes Moines

4h 45m

1 stop

TPA1:00 amTampa

$307

Southwest

Dec 18

TPA4:30 pmTampa

8h 05m

2 stops

DSM11:35 pmDes Moines

Dec 21

DSM5:10 amDes Moines

7h 25m

2 stops

TPA1:35 pmTampa

$317

Southwest

Dec 4

TPA7:20 amTampa

5h 05m

1 stop

DSM11:25 amDes Moines

Dec 7

DSM3:25 pmDes Moines

6h 00m

1 stop

TPA10:25 pmTampa

$335

Delta flights from Tampa to Des Moines

Our best Delta deals on Tampa to Des Moines flight tickets

Delta

Dec 16

TPA6:20 amTampa

5h 29m

1 stop

DSM10:49 amDes Moines

Dec 19

DSM6:43 pmDes Moines

4h 42m

1 stop

TPA12:25 amTampa

$293

Delta

Dec 18

TPA5:10 amTampa

6h 39m

1 stop

DSM10:49 amDes Moines

Dec 19

DSM6:43 pmDes Moines

4h 42m

1 stop

TPA12:25 amTampa

$334

Delta

Dec 16

TPA10:55 amTampa

6h 54m

1 stop

DSM4:49 pmDes Moines

Dec 22

DSM6:43 pmDes Moines

4h 42m

1 stop

TPA12:25 amTampa

$354

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 11/4

3:11 pm-3:25 pm

1 stop25h 14m

Des Moines

Sun 11/8

12:25 pm-7:10 am

1 stop17h 45m

$265

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Sat 12/19

5:20 am-10:49 am

1 stop6h 29m

Des Moines

Sat 12/19

6:43 pm-12:25 am

1 stop4h 42m

$293

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Thu 12/17

5:10 am-10:49 am

1 stop6h 39m

Des Moines

Sat 12/19

6:43 pm-12:25 am

1 stop4h 42m

$293

Quickest round-trip

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 12/16

6:20 am-10:49 am

1 stop5h 29m

Des Moines

Sat 12/19

6:43 pm-12:25 am

1 stop4h 42m

$293

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 11/4

7:08 am-3:25 pm

2 stops33h 17m

Des Moines

Sun 11/8

12:25 pm-7:10 am

1 stop17h 45m

$300

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Fri 12/18

6:10 pm-11:35 pm

1 stop6h 25m

Des Moines

Mon 12/21

7:15 pm-1:00 am

1 stop4h 45m

$307

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Mon 11/16

6:34 pm-11:26 pm

1 stop5h 52m

Des Moines

Wed 11/18

1:58 pm-10:42 pm

1 stop7h 44m

$403

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 11/4

5:08 pm-11:05 pm

1 stop6h 57m

Des Moines

Mon 11/9

3:31 pm-9:58 pm

1 stop5h 27m

$428

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 12/16

9:10 am-9:25 pm

2 stops13h 15m

Des Moines

Mon 12/21

5:00 am-12:44 pm

1 stop6h 44m

$440

TampaDes Moines

TPA Tampa - DSM Des Moines

TPADSM

Tampa

Wed 12/16

9:10 am-7:19 pm

2 stops11h 09m

Des Moines

Tue 12/22

5:30 am-1:12 pm

1 stop6h 42m

$440

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Tampa to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Tampa and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $297 to $580.
The lowest price recently found on this route was $265.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then August is your next best option. Flight prices from Tampa to Des Moines during August average around $426.

How have Tampa to Des Moines flight prices changed over time?

As of October 2026, prices for Tampa to Des Moines flights are approximately 150% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Des Moines

Best Price Found	$111
Fastest flight time	4h 58m
Direct flights	None

The best one-way flight to Des Moines from Tampa in the past 72 hours is $111. The best round-trip flight deal from Tampa to Des Moines found on momondo in the last 72 hours is $265.

The fastest flight from Tampa to Des Moines takes 4h 58m

There are no direct flights from Tampa to Des Moines. There are no popular flight routes from Tampa to Des Moines.

Search flight deals

Frequently asked questions about flying from Tampa to Des Moines

How far is Tampa to Des Moines by plane?
The distance between Tampa and Des Moines is about 1132.4 mi. Typically, this will take 4h 58m by plane in normal conditions.
When did momondo last update prices for flights from Tampa Airport to Des Moines Airport?
Prices for flights from Tampa Airport to Des Moines Airport are updated daily.
How many operators does momondo search for flights from Tampa Airport to Des Moines Airport?
As of October 2026, there are 3 operators available to choose from for flights from Tampa Airport to Des Moines Airport.
How old do you have to be to fly from Tampa Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Tampa to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Tampa to Des Moines is American Airlines (44% of total bookings). The next most popular airlines are Delta (34%) and United Airlines (21%).

Best airlines flying from Tampa to Des Moines

Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.0 12,186 reviews	Search American Airlines flights
Delta	PriceFrom $237	Free Cancellation	Rating 7.8 8,661 reviews	Search Delta flights
United Airlines	PriceFrom $635	Free Cancellation	Rating 7.3 10,404 reviews	Search United Airlines flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Pella

Urbandale

Newton

Osceola

Boone

Johnston

Oskaloosa

Grinnell

Norwalk

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Tampa to Des Moines for you.

Can I find flights from Tampa to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Tampa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Tampa to Des Moines?

Once you have performed a search for Tampa to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Tampa to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sat 11/21

Sat 11/28

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Tampa

Complete your trip

Feeling lucky

Airports servicing Iowa

Sioux City Sioux Gateway Airport

Cheap flights from Tampa to Des Moines from $111

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Des Moines departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Tampa to Des Moines

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Southwest flights from Tampa to Des Moines

Our best Southwest deals on Tampa to Des Moines flight tickets

Delta flights from Tampa to Des Moines

Our best Delta deals on Tampa to Des Moines flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Tampa to Des Moines

What is the typical price of a round-trip flight between Tampa and Des Moines?

What is the cheapest month to fly to Des Moines?

How have Tampa to Des Moines flight prices changed over time?

What is the cheapest airline that flies from Tampa to Des Moines?

What airlines fly to Des Moines?

When to book flights from Tampa to Des Moines

Cheap Tampa to Des Moines (TPA to DSM) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Tampa to Des Moines

Best airlines flying from Tampa to Des Moines

Compare and see reviews for airlines that fly from Tampa to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Tampa

According to popular flight searches on momondo this year

Complete your trip to Des Moines

Explore popular destinations other users love

According to popular flight searches on momondo this year