Cheap flights from St. Louis to Fort Myers from $124

In general, October is the cheapest month to fly from St. Louis to Fort Myers. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $312. If you are unable to visit Fort Myers during the month of October, then departing from St. Louis during the month September is also very affordable. Most momondo users find prices during this month for around $394.

The cheapest day to depart from St. Louis to Fort Myers is on a Thursday when prices can be found for as low as $411. Flights from St. Louis to Fort Myers on a Friday will generally be more expensive and average around $517. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

The cheapest time of day to fly to Fort Myers is in the afternoon when flights can be purchased for as low as $468. Flights at noon are often more expensive with an average ticket price of $683.

Fly from Lambert-St Louis to Fort Myers SW Florida Intl for the best Lambert-St Louis - Fort Myers SW Florida Intl flight prices

You are more likely to see cheaper flights to Fort Myers from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Fort Myers for around $438 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Fort Myers from St. Louis for as low as $372 on momondo.

There is only 1 cabin class available to choose from on St. Louis to Fort Myers flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 16% on your flight if you consider stops on a St. Louis to Fort Myers flight.

As of August 2026, prices for St. Louis to Fort Myers flights are approximately 87% more expensive when compared to flights at the same time last year.

Frontier is the most popular carrier operating from Lambert-St Louis to Fort Myers SW Florida Intl

Allegiant Air, Southwest and American Airlines are the top three most popular airlines that fly to Fort Myers from St. Louis according to our data. Allegiant Air is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Fort Myers. Keep in mind that there are 4 different airlines that fly to Fort Myers on a routine basis, so you have a few additional options to choose from.

As of August 2026, 1 flights take off from St. Louis and land in Fort Myers each day. The most common flight departure time for this route is 6:00AM, with 50% of daily flights taking off at noon.

The number of flights available between St. Louis and Fort Myers is 11 per week as of August 2026. The most frequent departure day is Sun, with 27% of weekly flights leaving on this day.