How long does it take to fly to Greenville?

Flight times from South Dakota to Greenville vary, but if you’re flying out of Sioux Falls and flying into Charlotte (one of the most popular routes), then the duration is 4h 40m on average. Another popular route from South Dakota to Greenville is flying from Rapid City to Charlotte, which will take roughly 4h 56m. Keep in mind that layovers or delays could extend your travel time.

What airlines fly to Greenville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Greenville from South Dakota according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 3 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Dakota to Greenville Airport?

Prices for flights from South Dakota to Greenville Airport were last updated today.

How many operators does momondo search for flights from South Dakota to Greenville Airport?

As of September 2026, there are 3 operators available to choose from for flights from South Dakota to Greenville Airport.

How old do you have to be to fly from South Dakota to Greenville Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Dakota to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$321 Cheap Flights from South Dakota to Greenville in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Dakota to Greenville

Round-trip

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:53 pm - 10:05 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

8h 12m1 stop Dallas/Fort Worth

6:43 pm - 12:41 amGSP Greenville-FSD Sioux Falls Joe Foss Field

6h 58m1 stop Chicago O'Hare Intl

$321American Airlines

Sat, Oct 24 - Sat, Oct 31

7:00 am - 4:07 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

8h 07m1 stop Chicago O'Hare Intl

6:27 pm - 12:44 amGSP Greenville-FSD Sioux Falls Joe Foss Field

7h 17m1 stop Chicago O'Hare Intl

$335American Airlines

Wed, Nov 18 - Sun, Nov 22

7:00 am - 6:55 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

10h 55m2 stops Chicago O'Hare Intl Charlotte Douglas

6:27 pm - 12:44 amGSP Greenville-FSD Sioux Falls Joe Foss Field

7h 17m1 stop Chicago O'Hare Intl

$390American Airlines

Wed, Nov 18 - Sun, Nov 22

3:03 pm - 8:58 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

4h 55m1 stop Chicago O'Hare Intl

11:58 am - 11:29 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

12h 31m2 stops Newark Chicago O'Hare Intl

$426United Airlines

Sat, Oct 24 - Sat, Oct 31

3:03 pm - 9:17 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

5h 14m1 stop Chicago O'Hare Intl

4:25 pm - 11:44 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

8h 19m1 stop Denver Intl

$433United Airlines

Tue, Oct 13 - Sat, Oct 17

12:53 pm - 10:05 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

8h 12m1 stop Dallas/Fort Worth

2:25 pm - 12:41 amGSP Greenville-FSD Sioux Falls Joe Foss Field

11h 16m2 stops Charlotte Douglas Chicago O'Hare Intl

$447American Airlines

Tue, Oct 13 - Sat, Oct 17

5:00 am - 3:08 pmRAP Rapid City-GSP Greenville

8h 08m1 stop Denver Intl

6:20 am - 10:15 amGSP Greenville-RAP Rapid City

5h 55m1 stop Chicago O'Hare Intl

$463United Airlines

Wed, Oct 7 - Tue, Oct 13

5:30 am - 11:00 amFSD Sioux Falls Joe Foss Field-GSP Greenville

4h 30m1 stop Atlanta Hartsfield-Jackson

3:39 pm - 7:55 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

5h 16m1 stop Atlanta Hartsfield-Jackson

$559Delta

Wed, Oct 14 - Mon, Oct 19

8:27 am - 7:57 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

10h 30m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

12:18 pm - 7:14 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

7h 56m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul

$629Delta

Thu, Dec 3 - Sun, Dec 6

6:39 am - 8:21 pmRAP Rapid City-GSP Greenville

11h 42m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

5:40 am - 10:45 amGSP Greenville-RAP Rapid City

7h 05m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul

$685Delta

Wed, Oct 7 - Tue, Oct 13

Cheap last minute flights

Enter your travel dates to find the best prices.

6:00 am - 3:08 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

8h 08m1 stop Denver Intl

5:46 pm - 11:11 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

6h 25m1 stop Chicago O'Hare Intl

$455United Airlines

Wed, Sep 30 - Mon, Oct 5

7:50 am - 7:00 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

10h 10m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

5:46 pm - 11:11 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

6h 25m1 stop Chicago O'Hare Intl

$659United Airlines

Wed, Sep 30 - Mon, Oct 5

5:04 pm - 9:17 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

27h 13m3 stops Denver Intl Missoula Johnson-Bell Field Chicago O'Hare Intl

5:46 pm - 11:11 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

6h 25m1 stop Chicago O'Hare Intl

$896United Airlines

Wed, Sep 30 - Mon, Oct 5

11:15 am - 11:13 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

10h 58m2 stops Chicago O'Hare Intl Newark

7:35 pm - 2:28 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

19h 53m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$980United Airlines

Mon, Sep 28 - Fri, Oct 2

11:15 am - 11:13 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

10h 58m2 stops Chicago O'Hare Intl Newark

5:46 pm - 2:28 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

21h 42m1 stop Chicago O'Hare Intl

$984United Airlines

Mon, Sep 28 - Fri, Oct 2

6:00 am - 3:08 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

8h 08m1 stop Denver Intl

4:25 pm - 11:44 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

8h 19m1 stop Denver Intl

$1,027United Airlines

Mon, Sep 28 - Thu, Oct 1

7:50 am - 1:33 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

4h 43m1 stop Chicago O'Hare Intl

4:25 pm - 11:44 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

8h 19m1 stop Denver Intl

$1,027United Airlines

Mon, Sep 28 - Fri, Oct 2

7:50 am - 6:11 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

9h 21m2 stops Chicago O'Hare Intl Newark

4:25 pm - 11:44 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

8h 19m1 stop Denver Intl

$1,032United Airlines

Mon, Sep 28 - Thu, Oct 1

5:04 pm - 9:17 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

27h 13m3 stops Denver Intl Missoula Johnson-Bell Field Chicago O'Hare Intl

5:46 pm - 11:11 pmGSP Greenville-FSD Sioux Falls Joe Foss Field

6h 25m1 stop Chicago O'Hare Intl

$1,121United Airlines

Mon, Sep 28 - Thu, Oct 1

12:06 pm - 10:53 pmFSD Sioux Falls Joe Foss Field-GSP Greenville

9h 47m2 stops Chicago O'Hare Intl Charlotte Douglas

1:36 pm - 12:29 amGSP Greenville-FSD Sioux Falls Joe Foss Field

11h 53m2 stops Charlotte Douglas Chicago O'Hare Intl

$1,348American Airlines

Mon, Sep 28 - Thu, Oct 1

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American Airlines flights from South Dakota to Greenville

Our best American Airlines deals on South Dakota to Greenville flight tickets

American Airlines

Oct 24

FSD12:53 pmSioux Falls Joe Foss Field

8h 12m

1 stop

GSP10:05 pmGreenville

Oct 31

GSP6:43 pmGreenville

6h 58m

1 stop

FSD12:41 amSioux Falls Joe Foss Field

$321

American Airlines

Nov 18

FSD7:00 amSioux Falls Joe Foss Field

8h 07m

1 stop

GSP4:07 pmGreenville

Nov 22

GSP6:27 pmGreenville

7h 17m

1 stop

FSD12:44 amSioux Falls Joe Foss Field

$335

American Airlines

Nov 18

FSD7:00 amSioux Falls Joe Foss Field

10h 55m

2 stops

GSP6:55 pmGreenville

Nov 22

GSP6:27 pmGreenville

7h 17m

1 stop

FSD12:44 amSioux Falls Joe Foss Field

$390

United Airlines flights from South Dakota to Greenville

Our best United Airlines deals on South Dakota to Greenville flight tickets

United Airlines

Oct 24

FSD3:03 pmSioux Falls Joe Foss Field

4h 55m

1 stop

GSP8:58 pmGreenville

Oct 31

GSP11:58 amGreenville

12h 31m

2 stops

FSD11:29 pmSioux Falls Joe Foss Field

$426

United Airlines

Oct 13

FSD3:03 pmSioux Falls Joe Foss Field

5h 14m

1 stop

GSP9:17 pmGreenville

Oct 17

GSP4:25 pmGreenville

8h 19m

1 stop

FSD11:44 pmSioux Falls Joe Foss Field

$433

United Airlines

Sep 30

FSD6:00 amSioux Falls Joe Foss Field

8h 08m

1 stop

GSP3:08 pmGreenville

Oct 5

GSP5:46 pmGreenville

6h 25m

1 stop

FSD11:11 pmSioux Falls Joe Foss Field

$455

momondo Fare Finder

Use the filters below to find and compare flights from South Dakota to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Sat 10/24

12:53 pm-10:05 pm

1 stop8h 12m

Greenville

Sat 10/31

6:43 pm-12:41 am

1 stop6h 58m

$321

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Wed 11/18

7:00 am-4:07 pm

1 stop8h 07m

Greenville

Sun 11/22

6:27 pm-12:44 am

1 stop7h 17m

$335

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Wed 11/18

7:00 am-6:55 pm

2 stops10h 55m

Greenville

Sun 11/22

6:27 pm-12:44 am

1 stop7h 17m

$390

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Sat 10/24

3:03 pm-8:58 pm

1 stop4h 55m

Greenville

Sat 10/31

11:58 am-11:29 pm

2 stops12h 31m

$426

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Tue 10/13

3:03 pm-9:17 pm

1 stop5h 14m

Greenville

Sat 10/17

4:25 pm-11:44 pm

1 stop8h 19m

$433

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Tue 10/13

12:53 pm-10:05 pm

1 stop8h 12m

Greenville

Sat 10/17

2:25 pm-12:41 am

2 stops11h 16m

$447

Rapid CityGreenville

RAP Rapid City - GSP Greenville

RAPGSP

Rapid City

Wed 10/7

5:00 am-3:08 pm

1 stop8h 08m

Greenville

Tue 10/13

6:20 am-10:15 am

1 stop5h 55m

$463

Quickest round-trip

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Wed 10/14

5:30 am-11:00 am

1 stop4h 30m

Greenville

Mon 10/19

3:39 pm-7:55 pm

1 stop5h 16m

$559

Sioux FallsGreenville

FSD Sioux Falls Joe Foss Field - GSP Greenville

FSDGSP

Sioux Falls Joe Foss Field

Thu 12/3

8:27 am-7:57 pm

2 stops10h 30m

Greenville

Sun 12/6

12:18 pm-7:14 pm

2 stops7h 56m

$629

Rapid CityGreenville

RAP Rapid City - GSP Greenville

RAPGSP

Rapid City

Wed 10/7

6:39 am-8:21 pm

2 stops11h 42m

Greenville

Tue 10/13

5:40 am-10:45 am

2 stops7h 05m

$685

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from South Dakota to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

Can stopping save me money on South Dakota to Greenville flights?

You could potentially save up to 49% on your flight if you consider stops on a South Dakota to Greenville flight.

Cheap South Dakota to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Dakota to Greenville

Best Price Found	$321
Fastest flight time	8h 08m
Direct flights	None

The best flight deal from South Dakota to Greenville found on momondo in the last 72 hours is $321

The fastest flight from South Dakota to Greenville takes 8h 08m

There are no direct flights from South Dakota to Greenville. There are no popular flight routes from South Dakota to Greenville.

Search flight deals

Frequently asked questions about flying from South Dakota to Greenville

When did momondo last update prices for flights from South Dakota to Greenville Airport?
Prices for flights from South Dakota to Greenville Airport were last updated today.
How many operators does momondo search for flights from South Dakota to Greenville Airport?
As of September 2026, there are 3 operators available to choose from for flights from South Dakota to Greenville Airport.
How old do you have to be to fly from South Dakota to Greenville Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Dakota to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Dakota to Greenville

Compare and see reviews for airlines that fly from South Dakota to Greenville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $258	Free Cancellation	Rating 7.8 8,605 reviews	Search Delta flights
American Airlines	PriceFrom $314	Free Cancellation	Rating 7.0 12,099 reviews	Search American Airlines flights
United Airlines	PriceFrom $356	Free Cancellation	Rating 7.4 10,242 reviews	Search United Airlines flights

Anderson

Greenwood

Simpsonville

Greer

Duncan

Seneca

Why use momondo?

Why should I use momondo to find a flight deal from South Dakota to Greenville?

Finding the right flight to Greenville from South Dakota is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from South Dakota to Greenville with flexible booking policies on momondo?

Flights from South Dakota to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from South Dakota to Greenville?

Once you have performed a search for South Dakota to Greenville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Dakota to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from South Dakota are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from South Dakota to Greenville from $321

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from South Dakota to Greenville departing on 10/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from South Dakota to Greenville

Our best American Airlines deals on South Dakota to Greenville flight tickets

United Airlines flights from South Dakota to Greenville

Our best United Airlines deals on South Dakota to Greenville flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Dakota to Greenville that are best for you.

See travel insights to Greenville from

How to get the cheapest flight ticket from South Dakota to Greenville

Can stopping save me money on South Dakota to Greenville flights?

What airlines fly to Greenville?

How long does it take to fly to Greenville?

Cheap South Dakota to Greenville flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from South Dakota to Greenville

Best airlines flying from South Dakota to Greenville

Compare and see reviews for airlines that fly from South Dakota to Greenville with momondo

Traveling to a place near Greenville?

Why use momondo?

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing South Carolina

Fly your favorite airline to Greenville

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Greenville

List of cabin classes available on flights landing in Greenville. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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