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Cheap flights from South Carolina to Santa Fe from $295

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Santa Fe departing on 12/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Santa Fe

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:25 pm - 8:35 pmCLT-SAF
6h 10m1 stop
United Airlines Logo
1:20 pm - 10:38 pmSAF-CLT
7h 18m1 stop
$385United Airlines
Find Deal
Fri, Mar 20 - Mon, Mar 23
United Airlines Logo
8:15 am - 12:40 pmCLT-SAF
6h 25m1 stop
United Airlines Logo
1:20 pm - 10:56 pmSAF-CLT
7h 36m1 stop
$389United Airlines
Find Deal
Mon, Dec 1 - Sat, Dec 6
United Airlines Logo
8:15 am - 12:40 pmCLT-SAF
6h 25m1 stop
United Airlines Logo
7:00 am - 5:05 pmSAF-CLT
8h 05m2 stops
$399United Airlines
Find Deal
Mon, Dec 1 - Sat, Dec 6
American Airlines Logo
5:29 am - 9:26 amCLT-SAF
5h 57m1 stop
American Airlines Logo
6:21 am - 1:35 pmSAF-CLT
5h 14m1 stop
$403American Airlines
Find Deal
Tue, Apr 7 - Sat, Apr 11
American Airlines Logo
5:15 am - 9:38 amCLT-SAF
6h 23m1 stop
American Airlines Logo
6:33 pm - 5:41 amSAF-CLT
9h 08m1 stop
$424American Airlines
Find Deal
Wed, Feb 25 - Sun, Mar 1
American Airlines Logo
12:52 pm - 9:48 pmHHH-SAF
10h 56m2 stops
American Airlines Logo
6:15 am - 6:12 pmSAF-HHH
9h 57m2 stops
$429American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
4:23 pm - 9:58 pmGSP-SAF
7h 35m1 stop
American Airlines Logo
6:18 am - 3:35 pmSAF-GSP
7h 17m1 stop
$459American Airlines
Find Deal
Thu, Jan 1 - Wed, Jul 1
American Airlines Logo
6:00 am - 2:57 pmGSP-SAF
10h 57m2 stops
American Airlines Logo
6:18 am - 3:35 pmSAF-GSP
7h 17m1 stop
$469American Airlines
Find Deal
Thu, Jan 1 - Wed, Jul 1
United Airlines Logo
10:20 am - 5:13 pmCLT-SAF
8h 53m2 stops
United Airlines Logo
1:19 pm - 10:47 pmSAF-CLT
7h 28m1 stop
$480United Airlines
Find Deal
Tue, Apr 7 - Sat, Apr 11
American Airlines Logo
6:00 am - 4:27 pmCHS-SAF
12h 27m2 stops
American Airlines Logo
6:31 pm - 8:42 amSAF-CHS
12h 11m2 stops
$490American Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16

United Airlines flights from South Carolina to Santa Fe

Our best United Airlines deals on South Carolina to Santa Fe flight tickets
United Airlines
Mar 20
CLT4:25 pmCharlotte Douglas
6h 10m
1 stop
SAF8:35 pmSanta Fe
Mar 23
SAF1:20 pmSanta Fe
7h 18m
1 stop
CLT10:38 pmCharlotte Douglas
$385
Find similar
United Airlines
Dec 1
CLT8:15 amCharlotte Douglas
6h 25m
1 stop
SAF12:40 pmSanta Fe
Dec 6
SAF1:20 pmSanta Fe
7h 36m
1 stop
CLT10:56 pmCharlotte Douglas
$389
Find similar
United Airlines
Dec 1
CLT8:15 amCharlotte Douglas
6h 25m
1 stop
SAF12:40 pmSanta Fe
Dec 6
SAF7:00 amSanta Fe
8h 05m
2 stops
CLT5:05 pmCharlotte Douglas
$399
Find similar

American Airlines flights from South Carolina to Santa Fe

Our best American Airlines deals on South Carolina to Santa Fe flight tickets
American Airlines
Apr 7
CLT5:29 amCharlotte Douglas
5h 57m
1 stop
SAF9:26 amSanta Fe
Apr 11
SAF6:21 amSanta Fe
5h 14m
1 stop
CLT1:35 pmCharlotte Douglas
$403
Find similar
American Airlines
Feb 25
CLT5:15 amCharlotte Douglas
6h 23m
1 stop
SAF9:38 amSanta Fe
Mar 1
SAF6:33 pmSanta Fe
9h 08m
1 stop
CLT5:41 amCharlotte Douglas
$424
Find similar
American Airlines
Dec 10
HHH12:52 pmHilton Head Island
10h 56m
2 stops
SAF9:48 pmSanta Fe
Dec 13
SAF6:15 amSanta Fe
9h 57m
2 stops
HHH6:12 pmHilton Head Island
$429
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 8, 2025.
Use the filters below to find and compare flights from South Carolina to Santa Fe that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Fri 3/20

4:25 pm-8:35 pm

1 stop6h 10m

Santa Fe

Mon 3/23

1:20 pm-10:38 pm

1 stop7h 18m

$385

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Mon 12/1

8:15 am-12:40 pm

1 stop6h 25m

Santa Fe

Sat 12/6

1:20 pm-10:56 pm

1 stop7h 36m

$389

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Mon 12/1

8:15 am-12:40 pm

1 stop6h 25m

Santa Fe

Sat 12/6

7:00 am-5:05 pm

2 stops8h 05m

$399

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Tue 4/7

5:29 am-9:26 am

1 stop5h 57m

Santa Fe

Sat 4/11

6:21 am-1:35 pm

1 stop5h 14m

$403

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Wed 2/25

5:15 am-9:38 am

1 stop6h 23m

Santa Fe

Sun 3/1

6:33 pm-5:41 am

1 stop9h 08m

$424

Hilton Head IslandSanta Fe

HHH - SAF

HHHSAF

Hilton Head Island

Wed 12/10

12:52 pm-9:48 pm

2 stops10h 56m

Santa Fe

Sat 12/13

6:15 am-6:12 pm

2 stops9h 57m

$429

GreenvilleSanta Fe

GSP - SAF

GSPSAF

Greenville

Thu 1/1

4:23 pm-9:58 pm

1 stop7h 35m

Santa Fe

Wed 7/1

6:18 am-3:35 pm

1 stop7h 17m

$459

GreenvilleSanta Fe

GSP - SAF

GSPSAF

Greenville

Thu 1/1

6:00 am-2:57 pm

2 stops10h 57m

Santa Fe

Wed 7/1

6:18 am-3:35 pm

1 stop7h 17m

$469

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Tue 4/7

10:20 am-5:13 pm

2 stops8h 53m

Santa Fe

Sat 4/11

1:19 pm-10:47 pm

1 stop7h 28m

$480

CharlestonSanta Fe

CHS - SAF

CHSSAF

Charleston

Wed 11/12

6:00 am-4:27 pm

2 stops12h 27m

Santa Fe

Sun 11/16

6:31 pm-8:42 am

2 stops12h 11m

$490

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Santa Fe from

How to get the cheapest flight ticket from South Carolina to Santa Fe

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Fe?

According to our data, Tuesday is the cheapest day to fly to Santa Fe from South Carolina. The lowest ticket price found for a Tuesday departure recently was $331. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Santa Fe on Monday is $947.

What is the cheapest time of day to depart on your flight to Santa Fe?

The cheapest time of day to fly to Santa Fe is at noon when flights can be purchased for as low as $363. Try not to purchase tickets in the morning because they tend to be around $551. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on South Carolina to Santa Fe flights?

You could potentially save up to 65% on your flight if you consider stops on a South Carolina to Santa Fe flight.

Cheap South Carolina to Santa Fe flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Santa Fe

Direct flights

None
There are no direct flights from South Carolina to Santa Fe. There are no popular flight routes from South Carolina to Santa Fe.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Santa Fe Airport?

    Prices for flights from South Carolina to Santa Fe Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Santa Fe Airport?

  • How old do you have to be to fly from South Carolina to Santa Fe Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Santa Fe Airport.

  • What documentation or ID do you need to fly to Santa Fe Airport?

    The required travel and health documents for your Santa Fe Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Fe Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Santa Fe

Compare and see reviews for airlines that fly from South Carolina to Santa Fe with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $264Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa
Los Alamos

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Santa Fe?

It is quick and easy to find South Carolina to Santa Fe flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Fe that suits you.

Can I find flights from South Carolina to Santa Fe with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Santa Fe flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Santa Fe?

Once you have performed a search for South Carolina to Santa Fe flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Santa Fe right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Santa Fe flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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