Cheap flights from South Carolina to Pennsylvania from $44

The month of September is, on average, the cheapest month to fly to Pennsylvania from South Carolina, with most prices found around $226. If you don’t want to visit Pennsylvania in September, then you should wait until October to fly from South Carolina, when ticket prices are also cheap, with an average price of $239.

The cheapest day to depart on your flight to Pennsylvania is on a Friday when prices can be found for as low as $388. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $832. These prices are subject to change though, so be sure to set up a Price Alert for flights to Pennsylvania.

Our most recent data shows that the best time of day to fly to Pennsylvania is in the morning. Flights from South Carolina to Pennsylvania during this time can be as low as $376. In contrast, the most expensive time of day to depart to Pennsylvania is at noon when prices are around $1,136.

Fly from Myrtle Beach Intl to Pittsburgh for the best South Carolina - Pennsylvania flight prices

You are more likely to see cheaper flights to Pennsylvania from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Pennsylvania for around $335 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Pennsylvania from South Carolina for as low as $222 on momondo.

There are 4 cabin classes available to choose from on South Carolina to Pennsylvania flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Spirit Airlines, Delta, and United Airlines are the most popular carriers operating from South Carolina to Pennsylvania

American Airlines, Frontier and Allegiant Air are the top three most popular airlines that fly to Pennsylvania from South Carolina according to our data. American Airlines is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Pennsylvania. Keep in mind that there are 8 different airlines that fly to Pennsylvania on a routine basis, so you have a few additional options to choose from.

As of April 2026, there are 224 flights per day flying from South Carolina to Pennsylvania. The most common time of day flights depart is 12:00PM, with 43% of flights taking off in the afternoon.

As of April 2026, 1,569 flights take off from South Carolina and land in Pennsylvania each week. The most common flight departure day for this route is Wed, with 17% of weekly flights taking off on this day.