What airlines fly to Missouri?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to Missouri from South Carolina according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 4 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Missouri on average per week?

As of May 2026, 112 flights take off from South Carolina and land in Missouri each week. The most common flight departure day for this route is Sun, with 19% of weekly flights taking off on this day.

What is the cheapest airline that flies from South Carolina to Missouri?

Southwest, Delta, and United Airlines are the most popular carriers operating from South Carolina to Missouri

How many flights depart from South Carolina to Missouri on average per day?

As of May 2026, there are 16 flights per day flying from South Carolina to Missouri. The most common time of day flights depart is 2:00PM, with 100% of flights taking off in the afternoon.

How long is the flight from South Carolina to Missouri?

The flight from South Carolina to Missouri depends on which airports you’re departing and arriving from and whether or not you have a layover. If you fly from Myrtle Beach (a popular airport in South Carolina) to St. Louis (the most popular airport in Missouri), then the flight time is 2h 05m on average. If you fly from Charleston (another popular airport in South Carolina) to St. Louis, then the average flight time is 2h 05m.

When did momondo last update prices for flights from South Carolina to Missouri?

Prices for flights from South Carolina to Missouri are updated daily.

How many operators does momondo search for flights from South Carolina to Missouri?

As of May 2026, there are 4 operators available to choose from for flights from South Carolina to Missouri.

How old do you have to be to fly from South Carolina to Missouri?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Missouri.

What documentation or ID do you need to fly to Missouri?

The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$95 Cheap Flights from South Carolina to Missouri in 2026

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Find the cheapest flights from South Carolina to Missouri

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:12 pm - 12:14 am

CLT

STL

12h 02m

1 stop

8:08 pm - 9:24 pm

STL

CLT

24h 16m

1 stop

$210Frontier

Tue, Aug 18 - Fri, Aug 21

1:00 pm - 11:57 pm

CLT

STL

11h 57m

1 stop

4:17 pm - 11:34 am

STL

CLT

18h 17m

1 stop

$213Frontier

Mon, Jun 8 - Tue, Jun 9

1:25 pm - 2:25 pm

CLT

STL

2h 00mnonstop

4:50 pm - 7:40 pm

STL

CLT

1h 50mnonstop

$217Southwest

Tue, Jul 14 - Tue, Jul 21

7:05 am - 8:03 am

CLT

STL

1h 58mnonstop

7:35 am - 10:30 am

STL

CLT

1h 55mnonstop

$218American Airlines

Tue, Oct 13 - Sat, Oct 17

7:50 am - 11:30 am

CLT

STL

4h 40m

1 stop

4:50 pm - 7:40 pm

STL

CLT

1h 50mnonstop

$227Southwest

Tue, Jul 14 - Tue, Jul 21

7:29 am - 2:02 pm

CHS

STL

7h 33m

1 stop

6:13 pm - 11:47 pm

STL

CHS

4h 34m

1 stop

$257American Airlines

Tue, Jun 9 - Tue, Jun 16

7:05 am - 11:47 am

CHS

STL

5h 42m

1 stop

6:00 am - 11:54 am

STL

CHS

4h 54m

1 stop

$267Delta

Tue, Aug 11 - Wed, Aug 12

6:40 pm - 11:29 pm

CHS

STL

5h 49m

1 stop

6:00 am - 2:16 pm

STL

CHS

7h 16m

1 stop

$271United Airlines

Sat, Jun 6 - Tue, Jun 9

7:10 am - 1:17 pm

CHS

STL

7h 07m

1 stop

3:42 pm - 8:43 pm

STL

CHS

4h 01m

1 stop

$277Delta

Thu, Sep 10 - Mon, Sep 14

6:30 am - 10:21 am

GSP

MCI

4h 51m

1 stop

12:00 pm - 6:59 pm

MCI

GSP

5h 59m

1 stop

$321United Airlines

Sat, Aug 29 - Sat, Sep 5

Southwest flights from South Carolina to Missouri

Our best Southwest deals on South Carolina to Missouri flight tickets

Southwest

Jul 14

CLT1:25 pmCharlotte Douglas

2h 00m

STL2:25 pmLambert-St Louis

Jul 21

STL4:50 pmLambert-St Louis

1h 50m

CLT7:40 pmCharlotte Douglas

$217

Southwest

Jul 14

CLT7:50 amCharlotte Douglas

4h 40m

1 stop

STL11:30 amLambert-St Louis

Jul 21

STL4:50 pmLambert-St Louis

1h 50m

CLT7:40 pmCharlotte Douglas

$227

Southwest

Jun 4

CLT4:40 pmCharlotte Douglas

2h 10m

STL5:50 pmLambert-St Louis

Jun 10

STL4:50 pmLambert-St Louis

1h 50m

CLT7:40 pmCharlotte Douglas

$228

Delta flights from South Carolina to Missouri

Our best Delta deals on South Carolina to Missouri flight tickets

Delta

Aug 4

CLT5:30 amCharlotte Douglas

5h 24m

1 stop

STL9:54 amLambert-St Louis

Aug 11

STL12:52 pmLambert-St Louis

6h 33m

1 stop

CLT8:25 pmCharlotte Douglas

$237

Delta

Jul 14

CLT6:00 amCharlotte Douglas

4h 31m

1 stop

STL9:31 amLambert-St Louis

Jul 21

STL6:58 pmLambert-St Louis

4h 00m

1 stop

CLT11:58 pmCharlotte Douglas

$247

Delta

Jun 2

CLT9:47 amCharlotte Douglas

4h 23m

1 stop

STL1:10 pmLambert-St Louis

Jun 4

STL6:00 amLambert-St Louis

4h 05m

1 stop

CLT11:05 amCharlotte Douglas

$248

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 8/18

1:12 pm-12:14 am

1 stop12h 02m

Lambert-St Louis

Fri 8/21

8:08 pm-9:24 pm

1 stop24h 16m

$210

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Mon 6/8

1:00 pm-11:57 pm

1 stop11h 57m

Lambert-St Louis

Tue 6/9

4:17 pm-11:34 am

1 stop18h 17m

$213

Quickest round-trip

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 7/14

1:25 pm-2:25 pm

Nonstop2h 00m

Lambert-St Louis

Tue 7/21

4:50 pm-7:40 pm

Nonstop1h 50m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 10/13

7:05 am-8:03 am

Nonstop1h 58m

Lambert-St Louis

Sat 10/17

7:35 am-10:30 am

Nonstop1h 55m

$218

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 7/14

7:50 am-11:30 am

1 stop4h 40m

Lambert-St Louis

Tue 7/21

4:50 pm-7:40 pm

Nonstop1h 50m

$227

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 6/9

7:29 am-2:02 pm

1 stop7h 33m

Lambert-St Louis

Tue 6/16

6:13 pm-11:47 pm

1 stop4h 34m

$257

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 8/11

7:05 am-11:47 am

1 stop5h 42m

Lambert-St Louis

Wed 8/12

6:00 am-11:54 am

1 stop4h 54m

$267

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 6/6

6:40 pm-11:29 pm

1 stop5h 49m

Lambert-St Louis

Tue 6/9

6:00 am-2:16 pm

1 stop7h 16m

$271

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 9/10

7:10 am-1:17 pm

1 stop7h 07m

Lambert-St Louis

Mon 9/14

3:42 pm-8:43 pm

1 stop4h 01m

$277

GreenvilleKansas City

GSP - MCI

GSPMCI

Greenville

Sat 8/29

6:30 am-10:21 am

1 stop4h 51m

Kansas City

Sat 9/5

12:00 pm-6:59 pm

1 stop5h 59m

$321

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Missouri?

In general, June is the cheapest month to fly from South Carolina to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $108. If you aren’t able to travel to Missouri during the month of June, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $125.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from South Carolina to Missouri is on a Thursday when prices can be found for as low as $287. Flights from South Carolina to Missouri on a Sunday will generally be more expensive and average around $606. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the morning. momondo users have found flights departing from South Carolina to Missouri in the morning for as low as $357. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly at noon, with an average ticket price of $538. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest South Carolina to Missouri flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Missouri flight prices

Can stopping save me money on South Carolina to Missouri flights?

You could potentially save up to 20% on your flight if you consider stops on a South Carolina to Missouri flight.

Cheap South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Missouri

Best Price Found	$219
Fastest flight time	1h 55m
Direct flights	Every day
Airports in Missouri	55 airports

The best one-way flight to Missouri from South Carolina in the past 72 hours is $219. The best round-trip flight deal from South Carolina to Missouri found on momondo in the last 72 hours is $388.

The fastest flight from South Carolina to Missouri takes 1h 55m

Direct flights go from South Carolina to Missouri every day.

There are 55 airports in Missouri. From South Carolina there are direct flights to Lambert-St Louis (STL).

Search flight deals

Frequently asked questions about flying from South Carolina to Missouri

When did momondo last update prices for flights from South Carolina to Missouri?
Prices for flights from South Carolina to Missouri are updated daily.
How many operators does momondo search for flights from South Carolina to Missouri?
As of May 2026, there are 4 operators available to choose from for flights from South Carolina to Missouri.
How old do you have to be to fly from South Carolina to Missouri?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Missouri.
What documentation or ID do you need to fly to Missouri?
The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from South Carolina to Missouri?
Based on momondo bookings for flights between South Carolina and Missouri, the leading plane model is Boeing 737-800 Passenger/BBJ2 (winglets), making up 22.22% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet 900 with 9.26%, Boeing 737 MAX 8 with 7.41%, and Boeing 737-900 Passenger/BBJ3 (winglets) with 7.41%.

Best airlines flying from South Carolina to Missouri

Compare and see reviews for airlines that fly from South Carolina to Missouri with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $128	Free Cancellation	Rating 7.9 8,451 reviews	Search Delta flights
American Airlines	PriceFrom $177	Free Cancellation	Rating 7.1 11,667 reviews	Search American Airlines flights
Southwest	PriceFrom $226	Free Cancellation	Rating 8.0 4,298 reviews	Search Southwest flights
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,699 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from South Carolina.

Can I find flights from South Carolina to Missouri with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Missouri from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Missouri?

Once you have performed a search for South Carolina to Missouri flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Missouri trip

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Popular cities in Missouri

Flights to New Yorkfrom $77

Flights to Los Angelesfrom $46

Flights to Orlandofrom $63

Flights to Miamifrom $56

Flights to Chicagofrom $59

Flights to San Franciscofrom $58

Flights to Las Vegasfrom $48

Flights to Washington, D.C.from $57

Flights to Bostonfrom $83

Flights to Atlantafrom $50

Flights to Fort Lauderdalefrom $56

Flights to Dallasfrom $50

Cheap flights from South Carolina to Missouri from $95

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Missouri departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Southwest flights from South Carolina to Missouri

Our best Southwest deals on South Carolina to Missouri flight tickets

Delta flights from South Carolina to Missouri

Our best Delta deals on South Carolina to Missouri flight tickets

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See travel insights to Missouri from

How to get the cheapest flight ticket from South Carolina to Missouri

What is the cheapest month to fly to Missouri?

What is the cheapest day to depart on your flight to Missouri?

What is the cheapest time of day to depart on your flight to Missouri?

What is the cheapest South Carolina to Missouri flight route?

Can stopping save me money on South Carolina to Missouri flights?

What is the cheapest airline that flies from South Carolina to Missouri?

What airlines fly to Missouri?

How many flights depart from South Carolina to Missouri on average per day?

How many flights depart from South Carolina to Missouri on average per week?

How long is the flight from South Carolina to Missouri?

Cheap South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Missouri

Best Price Found

Fastest flight time

Direct flights

Airports in Missouri

Frequently asked questions about flying from South Carolina to Missouri

Best airlines flying from South Carolina to Missouri

Compare and see reviews for airlines that fly from South Carolina to Missouri with momondo

Why use momondo?

An easier way to manage your Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Missouri

Popular cities in Missouri

Popular flights according to clicks in the last 7 days on momondo

South Carolina flight routes

According to popular flight searches on momondo this year

Missouri flight routes

According to popular flight searches on momondo this year

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