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Cheap flights from South Carolina to Missouri from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Missouri departing on 9/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Missouri

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
10:02 pm - 7:39 pmCLT  Charlotte Douglas-STL Lambert-St Louis
22h 37m1 stop Orlando
Frontier Logo
8:34 pm - 12:38 pmSTL  Lambert-St Louis-CLT Charlotte Douglas
15h 04m1 stop Orlando
$160Frontier
Thu, Oct 8 - Mon, Oct 12
Frontier Logo
10:02 pm - 7:39 pmCLT  Charlotte Douglas-STL Lambert-St Louis
22h 37m1 stop Orlando
Frontier Logo
8:34 pm - 4:38 pmSTL  Lambert-St Louis-CLT Charlotte Douglas
19h 04m1 stop Orlando
$168Frontier
Fri, Oct 9 - Mon, Oct 12
Frontier Logo
9:52 pm - 3:28 pmCLT  Charlotte Douglas-STL Lambert-St Louis
18h 36m1 stop Orlando
Frontier Logo
4:23 pm - 8:01 amSTL  Lambert-St Louis-CLT Charlotte Douglas
14h 38m1 stop Orlando
$170Frontier
Thu, Sep 3 - Mon, Sep 7
Delta Logo
5:30 am - 10:54 amCLT  Charlotte Douglas-SGF Springfield-Branson
6h 24m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 11:01 amSGF  Springfield-Branson-CLT Charlotte Douglas
4h 01m1 stop Atlanta Hartsfield-Jackson
$187Delta
Tue, Nov 10 - Tue, Nov 17
Delta Logo
11:52 am - 2:45 pmCLT  Charlotte Douglas-SGF Springfield-Branson
3h 53m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:00 pm - 11:54 pmSGF  Springfield-Branson-CLT Charlotte Douglas
6h 54m1 stop Atlanta Hartsfield-Jackson
$187Delta
Thu, Nov 12 - Sat, Nov 14
Delta Logo
11:51 am - 4:52 pmCLT  Charlotte Douglas-SGF Springfield-Branson
6h 01m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 11:06 amSGF  Springfield-Branson-CLT Charlotte Douglas
4h 06m1 stop Atlanta Hartsfield-Jackson
$187Delta
Mon, Oct 26 - Fri, Oct 30
Southwest Logo
11:50 am - 12:45 pmCLT  Charlotte Douglas-STL Lambert-St Louis
1h 55mnonstop
Southwest Logo
3:45 pm - 9:55 pmSTL  Lambert-St Louis-CLT Charlotte Douglas
5h 10m1 stop Nashville Intl
$192Southwest
Fri, Sep 11 - Mon, Sep 14
Southwest Logo
11:50 am - 12:45 pmCLT  Charlotte Douglas-STL Lambert-St Louis
1h 55mnonstop
Southwest Logo
3:45 pm - 9:55 pmSTL  Lambert-St Louis-CLT Charlotte Douglas
5h 10m1 stop Nashville Intl
$192Southwest
Fri, Sep 11 - Mon, Sep 14
American Airlines Logo
6:44 pm - 7:42 pmCLT  Charlotte Douglas-STL Lambert-St Louis
1h 58mnonstop
American Airlines Logo
5:23 am - 8:17 amSTL  Lambert-St Louis-CLT Charlotte Douglas
1h 54mnonstop
$197American Airlines
Sat, Sep 5 - Sun, Sep 6
American Airlines Logo
6:44 pm - 7:42 pmCLT  Charlotte Douglas-STL Lambert-St Louis
1h 58mnonstop
American Airlines Logo
5:23 am - 8:17 amSTL  Lambert-St Louis-CLT Charlotte Douglas
1h 54mnonstop
$198American Airlines
Sat, Sep 5 - Sun, Sep 6

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American Airlines flights from South Carolina to Missouri

Our best American Airlines deals on South Carolina to Missouri flight tickets
American Airlines
Sep 5
CLT6:44 pmCharlotte Douglas
1h 58m
STL7:42 pmLambert-St Louis
Sep 6
STL5:23 amLambert-St Louis
1h 54m
CLT8:17 amCharlotte Douglas
$197
American Airlines
Sep 5
CLT6:44 pmCharlotte Douglas
1h 58m
STL7:42 pmLambert-St Louis
Sep 12
STL6:53 amLambert-St Louis
1h 57m
CLT9:50 amCharlotte Douglas
$198
American Airlines
Sep 17
CLT9:50 pmCharlotte Douglas
1h 52m
STL10:42 pmLambert-St Louis
Sep 24
STL6:53 amLambert-St Louis
1h 57m
CLT9:50 amCharlotte Douglas
$199

United Airlines flights from South Carolina to Missouri

Our best United Airlines deals on South Carolina to Missouri flight tickets
United Airlines
Sep 5
CLT5:58 pmCharlotte Douglas
6h 40m
1 stop
STL11:38 pmLambert-St Louis
Sep 6
STL7:25 amLambert-St Louis
6h 26m
1 stop
CLT2:51 pmCharlotte Douglas
$212
United Airlines
Sep 5
CLT8:05 amCharlotte Douglas
4h 58m
1 stop
STL12:03 pmLambert-St Louis
Sep 6
STL6:00 amLambert-St Louis
7h 18m
2 stops
CLT2:18 pmCharlotte Douglas
$222
United Airlines
Sep 3
CLT7:00 amCharlotte Douglas
5h 17m
1 stop
STL11:17 amLambert-St Louis
Sep 6
STL6:00 amLambert-St Louis
7h 18m
2 stops
CLT2:18 pmCharlotte Douglas
$231

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from South Carolina to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSt. Louis

CLT Charlotte Douglas - STL Lambert-St Louis

CLTSTL

Charlotte Douglas

Thu 10/8

10:02 pm-7:39 pm

1 stop22h 37m

Lambert-St Louis

Mon 10/12

8:34 pm-12:38 pm

1 stop15h 04m

$160

CharlotteSt. Louis

CLT Charlotte Douglas - STL Lambert-St Louis

CLTSTL

Charlotte Douglas

Fri 10/9

10:02 pm-7:39 pm

1 stop22h 37m

Lambert-St Louis

Mon 10/12

8:34 pm-4:38 pm

1 stop19h 04m

$168

CharlotteSt. Louis

CLT Charlotte Douglas - STL Lambert-St Louis

CLTSTL

Charlotte Douglas

Thu 9/3

9:52 pm-3:28 pm

1 stop18h 36m

Lambert-St Louis

Mon 9/7

4:23 pm-8:01 am

1 stop14h 38m

$170

CharlotteSpringfield

CLT Charlotte Douglas - SGF Springfield-Branson

CLTSGF

Charlotte Douglas

Tue 11/10

5:30 am-10:54 am

1 stop6h 24m

Springfield-Branson

Tue 11/17

6:00 am-11:01 am

1 stop4h 01m

$187

CharlotteSpringfield

CLT Charlotte Douglas - SGF Springfield-Branson

CLTSGF

Charlotte Douglas

Thu 11/12

11:52 am-2:45 pm

1 stop3h 53m

Springfield-Branson

Sat 11/14

4:00 pm-11:54 pm

1 stop6h 54m

$187

CharlotteSpringfield

CLT Charlotte Douglas - SGF Springfield-Branson

CLTSGF

Charlotte Douglas

Mon 10/26

11:51 am-4:52 pm

1 stop6h 01m

Springfield-Branson

Fri 10/30

6:00 am-11:06 am

1 stop4h 06m

$187

CharlotteSt. Louis

CLT Charlotte Douglas - STL Lambert-St Louis

CLTSTL

Charlotte Douglas

Fri 9/11

11:50 am-12:45 pm

Nonstop1h 55m

Lambert-St Louis

Mon 9/14

3:45 pm-9:55 pm

1 stop5h 10m

$192

CharlotteSt. Louis

CLT Charlotte Douglas - STL Lambert-St Louis

CLTSTL

Charlotte Douglas

Fri 9/11

11:50 am-12:45 pm

Nonstop1h 55m

Lambert-St Louis

Mon 9/14

3:45 pm-9:55 pm

1 stop5h 10m

$192
Quickest round-trip

CharlotteSt. Louis

CLT Charlotte Douglas - STL Lambert-St Louis

CLTSTL

Charlotte Douglas

Sat 9/5

6:44 pm-7:42 pm

Nonstop1h 58m

Lambert-St Louis

Sun 9/6

5:23 am-8:17 am

Nonstop1h 54m

$197

CharlotteSt. Louis

CLT Charlotte Douglas - STL Lambert-St Louis

CLTSTL

Charlotte Douglas

Sat 9/5

6:44 pm-7:42 pm

Nonstop1h 58m

Lambert-St Louis

Sun 9/6

5:23 am-8:17 am

Nonstop1h 54m

$198

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from South Carolina to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from South Carolina to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $333. If you aren’t able to travel to Missouri during the month of September, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $345.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from South Carolina to Missouri is on a Wednesday when prices can be found for as low as $330. Flights from South Carolina to Missouri on a Sunday will generally be more expensive and average around $606. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the afternoon. momondo users have found flights departing from South Carolina to Missouri in the afternoon for as low as $394. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly at noon, with an average ticket price of $527. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest South Carolina to Missouri flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Missouri flight prices

What cabin class options are available on South Carolina to Missouri flights?

There is only 1 cabin class available to choose from on South Carolina to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Missouri flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Missouri.

Cheap South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Missouri

Best Price Found

$252

Fastest flight time

1h 52m

Direct flights

Every day

Airports in Missouri

55 airports
The best one-way flight to Missouri from South Carolina in the past 72 hours is $252. The best round-trip flight deal from South Carolina to Missouri found on momondo in the last 72 hours is $245.
The fastest flight from South Carolina to Missouri takes 1h 52m
Direct flights go from South Carolina to Missouri every day.
There are 55 airports in Missouri. From South Carolina there are direct flights to Lambert-St Louis (STL).
Search flight deals

Frequently asked questions about flying from South Carolina to Missouri

  • When did momondo last update prices for flights from South Carolina to Missouri?

    Prices for flights from South Carolina to Missouri are updated daily.

  • How many operators does momondo search for flights from South Carolina to Missouri?

  • How old do you have to be to fly from South Carolina to Missouri?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from South Carolina to Missouri?

Best airlines flying from South Carolina to Missouri

Compare and see reviews for airlines that fly from South Carolina to Missouri with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $158Free CancellationRating
7.8
8,502 reviews
Search Delta flights
American AirlinesPriceFrom $191Free CancellationRating
7.1
11,923 reviews
Search American Airlines flights
SouthwestPriceFrom $228Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
10,112 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from South Carolina.

Can I find flights from South Carolina to Missouri with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Missouri from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Missouri?

Once you have performed a search for South Carolina to Missouri flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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