What airlines fly to Missouri?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Missouri from South Carolina according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 4 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to Missouri?

Spirit Airlines, Frontier, and Southwest are the most popular carriers operating from South Carolina to Missouri

How many flights depart from South Carolina to Missouri on average per day?

As of July 2025, there are 9 flights per day flying from South Carolina to Missouri. The most common time of day flights depart is 5:00PM, with 75% of flights taking off in the afternoon.

How many flights depart from South Carolina to Missouri on average per week?

As of July 2025, 68 flights take off from South Carolina and land in Missouri each week. The most common flight departure day for this route is Thu, with 24% of weekly flights taking off on this day.

How long is the flight from South Carolina to Missouri?

The flight from South Carolina to Missouri depends on which airports you’re departing and arriving from and whether or not you have a layover. If you fly from Charleston (a popular airport in South Carolina) to St. Louis (the most popular airport in Missouri), then the flight time is 2h 05m on average. If you fly from Greenville (another popular airport in South Carolina) to St. Louis, then the average flight time is 3h 23m.

When did momondo last update prices for flights from South Carolina to Missouri?

Prices for flights from South Carolina to Missouri are updated daily.

How many operators does momondo search for flights from South Carolina to Missouri?

As of July 2025, there are 5 operators available to choose from for flights from South Carolina to Missouri.

How old do you have to be to fly from South Carolina to Missouri?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Missouri.

What documentation or ID do you need to fly to Missouri?

The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$85 Cheap Flights from South Carolina to Missouri in 2025

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Find the cheapest flights from South Carolina to Missouri

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

2:14 pm - 1:32 pmCLT-STL

24h 18m1 stop

12:05 pm - 1:29 pmSTL-CLT

24h 24m1 stop

$169Spirit Airlines

Find Deal

Thu, Aug 28 - Sun, Sep 7

7:03 pm - 11:47 pmCLT-STL

5h 44m1 stop

8:00 am - 8:46 pmSTL-CLT

11h 46m1 stop

$188Frontier

Find Deal

Thu, Aug 14 - Tue, Aug 19

11:10 am - 12:11 pmCLT-STL

2h 01mnonstop

5:27 am - 8:25 amSTL-CLT

1h 58mnonstop

$216American Airlines

Find Deal

Sat, Aug 30 - Sun, Aug 31

8:56 am - 10:17 amCLT-MCI

2h 21mnonstop

5:15 pm - 8:40 pmMCI-CLT

2h 25mnonstop

$217American Airlines

Find Deal

Sat, Aug 30 - Sat, Sep 13

10:35 am - 11:30 amCLT-STL

1h 55mnonstop

2:45 pm - 5:35 pmSTL-CLT

1h 50mnonstop

$217Southwest

Find Deal

Sat, Aug 30 - Mon, Sep 1

1:50 pm - 2:55 pmSAV-STL

2h 05mnonstop

10:25 am - 1:15 pmSTL-SAV

1h 50mnonstop

$217Southwest

Find Deal

Sat, Aug 30 - Sat, Sep 6

6:50 am - 9:15 amSAV-STL

3h 25m1 stop

6:00 am - 11:14 amSTL-SAV

4h 14m1 stop

$227Delta

Find Deal

Tue, Sep 2 - Tue, Sep 9

1:27 pm - 4:36 pmCLT-STL

4h 09m1 stop

7:00 am - 12:59 pmSTL-CLT

4h 59m1 stop

$235Delta

Find Deal

Sat, Aug 30 - Sun, Aug 31

10:35 am - 2:19 pmCLT-STL

4h 44m1 stop

3:20 pm - 11:59 pmSTL-CLT

7h 39m2 stops

$265United Airlines

Find Deal

Wed, Sep 3 - Fri, Sep 5

6:07 pm - 11:44 pmGSP-STL

6h 37m1 stop

6:35 am - 2:16 pmSTL-GSP

6h 41m2 stops

$267United Airlines

Find Deal

Tue, Aug 26 - Sun, Aug 31

Spirit Airlines flights from South Carolina to Missouri

Our best Spirit Airlines deals on South Carolina to Missouri flight tickets

Spirit Airlines

Aug 28

CLT2:14 pmCharlotte Douglas

24h 18m

1 stop

STL1:32 pmLambert-St Louis

Sep 7

STL12:05 pmLambert-St Louis

24h 24m

1 stop

CLT1:29 pmCharlotte Douglas

$169

Find similar

Spirit Airlines

Aug 28

CLT2:14 pmCharlotte Douglas

24h 18m

1 stop

STL1:32 pmLambert-St Louis

Sep 4

STL10:35 amLambert-St Louis

11h 24m

1 stop

CLT10:59 pmCharlotte Douglas

$193

Find similar

Spirit Airlines

Oct 18

MYR1:21 pmMyrtle Beach Intl

10h 46m

1 stop

MCI11:07 pmKansas City

Oct 20

MCI5:15 amKansas City

11h 06m

1 stop

MYR5:21 pmMyrtle Beach Intl

$195

Find similar

Frontier flights from South Carolina to Missouri

Our best Frontier deals on South Carolina to Missouri flight tickets

Frontier

Aug 14

CLT7:03 pmCharlotte Douglas

5h 44m

1 stop

STL11:47 pmLambert-St Louis

Aug 19

STL8:00 amLambert-St Louis

11h 46m

1 stop

CLT8:46 pmCharlotte Douglas

$188

Find similar

Frontier

Aug 11

CLT9:17 pmCharlotte Douglas

27h 30m

1 stop

STL11:47 pmLambert-St Louis

Aug 16

STL5:40 pmLambert-St Louis

17h 02m

1 stop

CLT11:42 amCharlotte Douglas

$195

Find similar

Frontier

Aug 29

CLT9:42 amCharlotte Douglas

5h 39m

1 stop

STL2:21 pmLambert-St Louis

Aug 31

STL10:17 amLambert-St Louis

10h 46m

1 stop

CLT10:03 pmCharlotte Douglas

$198

Find similar

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 8/28

2:14 pm-1:32 pm

1 stop24h 18m

Lambert-St Louis

Sun 9/7

12:05 pm-1:29 pm

1 stop24h 24m

$169

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 8/14

7:03 pm-11:47 pm

1 stop5h 44m

Lambert-St Louis

Tue 8/19

8:00 am-8:46 pm

1 stop11h 46m

$188

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 8/30

11:10 am-12:11 pm

Nonstop2h 01m

Lambert-St Louis

Sun 8/31

5:27 am-8:25 am

Nonstop1h 58m

$216

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 8/30

8:56 am-10:17 am

Nonstop2h 21m

Kansas City

Sat 9/13

5:15 pm-8:40 pm

Nonstop2h 25m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 8/30

10:35 am-11:30 am

Nonstop1h 55m

Lambert-St Louis

Mon 9/1

2:45 pm-5:35 pm

Nonstop1h 50m

$217

SavannahSt. Louis

SAV - STL

SAVSTL

Savannah/Hilton Head

Sat 8/30

1:50 pm-2:55 pm

Nonstop2h 05m

Lambert-St Louis

Sat 9/6

10:25 am-1:15 pm

Nonstop1h 50m

$217

SavannahSt. Louis

SAV - STL

SAVSTL

Savannah/Hilton Head

Tue 9/2

6:50 am-9:15 am

1 stop3h 25m

Lambert-St Louis

Tue 9/9

6:00 am-11:14 am

1 stop4h 14m

$227

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 8/30

1:27 pm-4:36 pm

1 stop4h 09m

Lambert-St Louis

Sun 8/31

7:00 am-12:59 pm

1 stop4h 59m

$235

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 9/3

10:35 am-2:19 pm

1 stop4h 44m

Lambert-St Louis

Fri 9/5

3:20 pm-11:59 pm

2 stops7h 39m

$265

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 8/26

6:07 pm-11:44 pm

1 stop6h 37m

Lambert-St Louis

Sun 8/31

6:35 am-2:16 pm

2 stops6h 41m

$267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Missouri?

In general, August is the cheapest month to fly from South Carolina to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $340. If you aren’t able to travel to Missouri during the month of August, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $355.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from South Carolina to Missouri is on a Thursday when prices can be found for as low as $336. Flights from South Carolina to Missouri on a Saturday will generally be more expensive and average around $646. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the afternoon. momondo users have found flights departing from South Carolina to Missouri in the afternoon for as low as $388. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $426. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest South Carolina to Missouri flight route?

Fly from Charleston to Kansas City for the best South Carolina - Missouri flight prices

How far in advance should I book a flight to Missouri?

You are more likely to see cheaper flights to Missouri from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $392 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from South Carolina for as low as $330 on momondo.

What cabin class options are available on South Carolina to Missouri flights?

There are 1 cabin classes available to choose from on South Carolina to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Missouri flights?

You could potentially save up to 44% on your flight if you consider stops on a South Carolina to Missouri flight.

Cheap South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Missouri

Best Price Found	$85
Fastest flight time	1h 52m
Direct flights	Every day
Airports in Missouri	3 airports

The best one-way flight to Missouri from South Carolina in the past 72 hours is $85. The best round-trip flight deal from South Carolina to Missouri found on momondo in the last 72 hours is $169.

The fastest flight from South Carolina to Missouri takes 1h 52m

Direct flights go from South Carolina to Missouri every day.

There are 3 airports near Missouri: Kansas City (MCI), Springfield-Branson (SGF), Lambert-St Louis (STL)

Search flight deals

When did momondo last update prices for flights from South Carolina to Missouri?
Prices for flights from South Carolina to Missouri are updated daily.
How many operators does momondo search for flights from South Carolina to Missouri?
As of July 2025, there are 5 operators available to choose from for flights from South Carolina to Missouri.
How old do you have to be to fly from South Carolina to Missouri?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Missouri.
What documentation or ID do you need to fly to Missouri?
The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from South Carolina to Missouri?
Based on momondo bookings for flights between South Carolina and Missouri, the leading plane model is Boeing 737-700 Passenger/BBJ1 (winglets), making up 39.29% of the total bookings. Other popular models include Boeing 737 MAX 8 with 17.86%, Boeing 737-900 Passenger/BBJ3 (winglets) with 7.14%, and Airbus A220-300 with 5.36%.

Best airlines flying from South Carolina to Missouri

Compare and see reviews for airlines that fly from South Carolina to Missouri with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $139	Free Cancellation	Rating 8.0 7,981 reviews	Search Delta flights
American Airlines	PriceFrom $172	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Spirit Airlines	PriceFrom $199	Free Cancellation	Rating 6.3 8,048 reviews	Search Spirit Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 8.0 4,246 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from South Carolina.

Can I find flights from South Carolina to Missouri with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Missouri from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Missouri?

Once you have performed a search for South Carolina to Missouri flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to Missouri

Popular cities in Missouri

Flights to New Yorkfrom $39

Flights to Los Angelesfrom $37

Flights to Miamifrom $58

Flights to Chicagofrom $59

Flights to Orlandofrom $54

Flights to Las Vegasfrom $35

Flights to San Franciscofrom $49

Flights to Washington, D.C.from $49

Flights to Bostonfrom $77

Flights to Atlantafrom $29

Flights to Dallasfrom $55

Flights to Seattlefrom $93

Cheap flights from South Carolina to Missouri from $85

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Missouri departing on 10/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

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Find the cheapest flights from South Carolina to Missouri

Cheap round-trip flights

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Cheap last minute flights

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Spirit Airlines flights from South Carolina to Missouri

Our best Spirit Airlines deals on South Carolina to Missouri flight tickets

Frontier flights from South Carolina to Missouri

Our best Frontier deals on South Carolina to Missouri flight tickets

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Use the filters below to find and compare flights from South Carolina to Missouri that are best for you.

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How to get the cheapest flight ticket from South Carolina to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

What is the cheapest day to depart on your flight to Missouri?

What is the cheapest time of day to depart on your flight to Missouri?

What is the cheapest South Carolina to Missouri flight route?

Fly from Charleston to Kansas City for the best South Carolina - Missouri flight prices

How far in advance should I book a flight to Missouri?

What cabin class options are available on South Carolina to Missouri flights?

There are 1 cabin classes available to choose from on South Carolina to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Missouri flights?

You could potentially save up to 44% on your flight if you consider stops on a South Carolina to Missouri flight.

What is the cheapest airline that flies from South Carolina to Missouri?

Spirit Airlines, Frontier, and Southwest are the most popular carriers operating from South Carolina to Missouri

What airlines fly to Missouri?

How many flights depart from South Carolina to Missouri on average per day?

As of July 2025, there are 9 flights per day flying from South Carolina to Missouri. The most common time of day flights depart is 5:00PM, with 75% of flights taking off in the afternoon.

How many flights depart from South Carolina to Missouri on average per week?

As of July 2025, 68 flights take off from South Carolina and land in Missouri each week. The most common flight departure day for this route is Thu, with 24% of weekly flights taking off on this day.

How long is the flight from South Carolina to Missouri?

Cheap South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Missouri

Best Price Found

Fastest flight time

Direct flights

Airports in Missouri

When did momondo last update prices for flights from South Carolina to Missouri?

How many operators does momondo search for flights from South Carolina to Missouri?

How old do you have to be to fly from South Carolina to Missouri?

What documentation or ID do you need to fly to Missouri?

What is the most popular plane model from South Carolina to Missouri?

Best airlines flying from South Carolina to Missouri

Compare and see reviews for airlines that fly from South Carolina to Missouri with momondo

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Missouri?

Can I find flights from South Carolina to Missouri with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Missouri?

I’m not ready to book a flight from South Carolina to Missouri right now. Can momondo alert me if prices change?

An easier way to manage your Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Missouri

Popular cities in Missouri

Popular flights according to clicks in the last 7 days on momondo