How long is the flight from South Carolina to Missouri?

The flight from South Carolina to Missouri depends on which airports you’re departing and arriving from and whether or not you have a layover. If you fly from Charleston (a popular airport in South Carolina) to St. Louis (the most popular airport in Missouri), then the flight time is 2h 05m on average. If you fly from Columbia (another popular airport in South Carolina) to St. Louis, then the average flight time is 3h 34m.

How many flights depart from South Carolina to Missouri on average per day?

As of September 2025, there are 16 flights per day flying from South Carolina to Missouri. The most common time of day flights depart is 11:00AM, with 77% of flights taking off at noon.

What airlines fly to Missouri?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Missouri from South Carolina according to our data. American Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 4 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Missouri on average per week?

As of September 2025, 118 flights take off from South Carolina and land in Missouri each week. The most common flight departure day for this route is Thu, with 19% of weekly flights taking off on this day.

What is the cheapest airline that flies from South Carolina to Missouri?

Frontier, United Airlines, and Spirit Airlines are the most popular carriers operating from South Carolina to Missouri

When did momondo last update prices for flights from South Carolina to Missouri?

Prices for flights from South Carolina to Missouri are updated daily.

How many operators does momondo search for flights from South Carolina to Missouri?

As of September 2025, there are 5 operators available to choose from for flights from South Carolina to Missouri.

How old do you have to be to fly from South Carolina to Missouri?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Missouri.

What documentation or ID do you need to fly to Missouri?

The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$72 Cheap Flights from South Carolina to Missouri in 2025/26

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Find the cheapest flights from South Carolina to Missouri

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

7:00 am - 12:35 pmCHS-STL

6h 35m1 stop

6:00 am - 2:12 pmSTL-CHS

7h 12m1 stop

$197Delta

Find Deal

Wed, Oct 22 - Sun, Oct 26

10:11 pm - 9:04 amCLT-MCI

11h 53m1 stop

1:44 pm - 9:06 pmMCI-CLT

6h 22m1 stop

$206Spirit Airlines

Find Deal

Sun, Nov 9 - Wed, Jan 21

2:35 pm - 7:30 pmCAE-STL

5h 55m1 stop

9:14 am - 2:05 pmSTL-CAE

3h 51m1 stop

$212American Airlines

Find Deal

Sat, Oct 18 - Sat, Oct 25

6:07 pm - 7:33 pmCLT-MCI

26h 26m1 stop

10:09 am - 12:34 pmMCI-CLT

25h 25m1 stop

$220Multiple Airlines

Find Deal

Thu, Oct 30 - Wed, Nov 5

6:30 am - 10:49 amCLT-STL

5h 19m1 stop

6:30 am - 2:10 pmSTL-CLT

6h 40m2 stops

$222United Airlines

Find Deal

Wed, Oct 15 - Wed, Oct 22

5:59 pm - 11:54 pmCAE-STL

6h 55m2 stops

6:00 am - 2:05 pmSTL-CAE

7h 05m2 stops

$223American Airlines

Find Deal

Sat, Oct 18 - Sat, Oct 25

9:15 pm - 12:15 amCLT-STL

4h 00m1 stop

5:05 pm - 7:50 pmSTL-CLT

1h 45mnonstop

$227Southwest

Find Deal

Sat, Dec 27 - Tue, Dec 30

11:52 am - 10:37 amSAV-STL

23h 45m2 stops

10:57 am - 10:12 amSTL-SAV

22h 15m1 stop

$230Multiple Airlines

Find Deal

Wed, Oct 22 - Sun, Oct 26

4:20 pm - 10:05 pmCLT-STL

6h 45m1 stop

2:05 pm - 11:20 pmSTL-CLT

8h 15m2 stops

$232Southwest

Find Deal

Wed, Oct 15 - Mon, Oct 27

2:53 pm - 11:57 pmCAE-STL

10h 04m2 stops

5:00 am - 10:25 amSTL-CAE

4h 25m1 stop

$264United Airlines

Find Deal

Wed, Oct 1 - Sun, Oct 5

Delta flights from South Carolina to Missouri

Our best Delta deals on South Carolina to Missouri flight tickets

Delta

Oct 22

CHS7:00 amCharleston

6h 35m

1 stop

STL12:35 pmLambert-St Louis

Oct 26

STL6:00 amLambert-St Louis

7h 12m

1 stop

CHS2:12 pmCharleston

$197

Find similar

Delta

Oct 11

CLT5:25 pmCharlotte Douglas

4h 08m

1 stop

STL8:33 pmLambert-St Louis

Oct 14

STL9:10 amLambert-St Louis

6h 30m

1 stop

CLT4:40 pmCharlotte Douglas

$217

Find similar

Delta

Nov 25

CLT6:00 amCharlotte Douglas

4h 46m

1 stop

STL9:46 amLambert-St Louis

Nov 27

STL6:40 amLambert-St Louis

7h 10m

1 stop

CLT2:50 pmCharlotte Douglas

$237

Find similar

American Airlines flights from South Carolina to Missouri

Our best American Airlines deals on South Carolina to Missouri flight tickets

American Airlines

Oct 18

CAE2:35 pmColumbia Metropolitan

5h 55m

1 stop

STL7:30 pmLambert-St Louis

Oct 25

STL9:14 amLambert-St Louis

3h 51m

1 stop

CAE2:05 pmColumbia Metropolitan

$212

Find similar

American Airlines

Oct 18

CAE5:59 pmColumbia Metropolitan

6h 55m

2 stops

STL11:54 pmLambert-St Louis

Oct 25

STL6:00 amLambert-St Louis

7h 05m

2 stops

CAE2:05 pmColumbia Metropolitan

$223

Find similar

American Airlines

Oct 11

CLT7:15 amCharlotte Douglas

2h 01m

STL8:16 amLambert-St Louis

Oct 14

STL6:00 amLambert-St Louis

5h 32m

1 stop

CLT12:32 pmCharlotte Douglas

$231

Find similar

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 10/22

7:00 am-12:35 pm

1 stop6h 35m

Lambert-St Louis

Sun 10/26

6:00 am-2:12 pm

1 stop7h 12m

$197

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sun 11/9

10:11 pm-9:04 am

1 stop11h 53m

Kansas City

Wed 1/21

1:44 pm-9:06 pm

1 stop6h 22m

$206

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Sat 10/18

2:35 pm-7:30 pm

1 stop5h 55m

Lambert-St Louis

Sat 10/25

9:14 am-2:05 pm

1 stop3h 51m

$212

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Thu 10/30

6:07 pm-7:33 pm

1 stop26h 26m

Kansas City

Wed 11/5

10:09 am-12:34 pm

1 stop25h 25m

$220

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/15

6:30 am-10:49 am

1 stop5h 19m

Lambert-St Louis

Wed 10/22

6:30 am-2:10 pm

2 stops6h 40m

$222

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Sat 10/18

5:59 pm-11:54 pm

2 stops6h 55m

Lambert-St Louis

Sat 10/25

6:00 am-2:05 pm

2 stops7h 05m

$223

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 12/27

9:15 pm-12:15 am

1 stop4h 00m

Lambert-St Louis

Tue 12/30

5:05 pm-7:50 pm

Nonstop1h 45m

$227

SavannahSt. Louis

SAV - STL

SAVSTL

Savannah/Hilton Head

Wed 10/22

11:52 am-10:37 am

2 stops23h 45m

Lambert-St Louis

Sun 10/26

10:57 am-10:12 am

1 stop22h 15m

$230

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 10/15

4:20 pm-10:05 pm

1 stop6h 45m

Lambert-St Louis

Mon 10/27

2:05 pm-11:20 pm

2 stops8h 15m

$232

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Wed 10/1

2:53 pm-11:57 pm

2 stops10h 04m

Lambert-St Louis

Sun 10/5

5:00 am-10:25 am

1 stop4h 25m

$264

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How to get the cheapest flight ticket from South Carolina to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from South Carolina to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $337. If you aren’t able to travel to Missouri during the month of September, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $342.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from South Carolina to Missouri is on a Thursday when prices can be found for as low as $336. Flights from South Carolina to Missouri on a Saturday will generally be more expensive and average around $646. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the afternoon. momondo users have found flights departing from South Carolina to Missouri in the afternoon for as low as $388. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the evening, with an average ticket price of $400. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest South Carolina to Missouri flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Missouri flight prices

How far in advance should I book a flight to Missouri?

You are more likely to see cheaper flights to Missouri from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $397 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from South Carolina for as low as $331 on momondo.

What cabin class options are available on South Carolina to Missouri flights?

There is only 1 cabin class available to choose from on South Carolina to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Missouri flights?

You could potentially save up to 32% on your flight if you consider stops on a South Carolina to Missouri flight.

Cheap South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Missouri

Best Price Found	$199
Fastest flight time	1h 56m
Direct flights	Every day
Airports in Missouri	3 airports

The best one-way flight to Missouri from South Carolina in the past 72 hours is $199. The best round-trip flight deal from South Carolina to Missouri found on momondo in the last 72 hours is $277.

The fastest flight from South Carolina to Missouri takes 1h 56m

Direct flights go from South Carolina to Missouri every day.

There are 3 airports near Missouri: Kansas City (MCI), Springfield-Branson (SGF), Lambert-St Louis (STL)

Search flight deals

When did momondo last update prices for flights from South Carolina to Missouri?
Prices for flights from South Carolina to Missouri are updated daily.
How many operators does momondo search for flights from South Carolina to Missouri?
As of September 2025, there are 5 operators available to choose from for flights from South Carolina to Missouri.
How old do you have to be to fly from South Carolina to Missouri?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Missouri.
What documentation or ID do you need to fly to Missouri?
The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from South Carolina to Missouri?
Based on momondo bookings for flights between South Carolina and Missouri, the leading plane model is Boeing 737-700 Passenger/BBJ1 (winglets), making up 42.86% of the total bookings. Other popular models include Boeing 737 MAX 8 with 12.24%, Boeing 737-900 Passenger/BBJ3 (winglets) with 8.16%, and Embraer 175 (Enhanced Winglets) with 4.08%.

Best airlines flying from South Carolina to Missouri

Compare and see reviews for airlines that fly from South Carolina to Missouri with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $139	Free Cancellation	Rating 7.9 7,964 reviews	Search Delta flights
Spirit Airlines	PriceFrom $199	Free Cancellation	Rating 6.3 8,030 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $204	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Southwest	PriceFrom $226	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from South Carolina.

Can I find flights from South Carolina to Missouri with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Missouri from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Missouri?

Once you have performed a search for South Carolina to Missouri flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Missouri trip

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Find better results for your trip to Missouri

Popular cities in Missouri

Flights to New Yorkfrom $49

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Flights to Chicagofrom $47

Flights to Orlandofrom $60

Flights to Las Vegasfrom $48

Flights to San Franciscofrom $53

Flights to Washington, D.C.from $49

Flights to Bostonfrom $73

Flights to Atlantafrom $51

Flights to Dallasfrom $56

Flights to Seattlefrom $86

Cheap flights from South Carolina to Missouri from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Missouri departing on 10/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from South Carolina to Missouri

Cheap round-trip flights

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Cheap last minute flights

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Delta flights from South Carolina to Missouri

Our best Delta deals on South Carolina to Missouri flight tickets

American Airlines flights from South Carolina to Missouri

Our best American Airlines deals on South Carolina to Missouri flight tickets

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How to get the cheapest flight ticket from South Carolina to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

What is the cheapest day to depart on your flight to Missouri?

What is the cheapest time of day to depart on your flight to Missouri?

What is the cheapest South Carolina to Missouri flight route?

Fly from Charleston to Lambert-St Louis for the best South Carolina - Missouri flight prices

How far in advance should I book a flight to Missouri?

What cabin class options are available on South Carolina to Missouri flights?

There is only 1 cabin class available to choose from on South Carolina to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Missouri flights?

You could potentially save up to 32% on your flight if you consider stops on a South Carolina to Missouri flight.

What is the cheapest airline that flies from South Carolina to Missouri?

Frontier, United Airlines, and Spirit Airlines are the most popular carriers operating from South Carolina to Missouri

What airlines fly to Missouri?

How many flights depart from South Carolina to Missouri on average per day?

As of September 2025, there are 16 flights per day flying from South Carolina to Missouri. The most common time of day flights depart is 11:00AM, with 77% of flights taking off at noon.

How many flights depart from South Carolina to Missouri on average per week?

As of September 2025, 118 flights take off from South Carolina and land in Missouri each week. The most common flight departure day for this route is Thu, with 19% of weekly flights taking off on this day.

How long is the flight from South Carolina to Missouri?

Cheap South Carolina to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Missouri

Best Price Found

Fastest flight time

Direct flights

Airports in Missouri

When did momondo last update prices for flights from South Carolina to Missouri?

How many operators does momondo search for flights from South Carolina to Missouri?

How old do you have to be to fly from South Carolina to Missouri?

What documentation or ID do you need to fly to Missouri?

What is the most popular plane model from South Carolina to Missouri?

Best airlines flying from South Carolina to Missouri

Compare and see reviews for airlines that fly from South Carolina to Missouri with momondo

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Missouri?

Can I find flights from South Carolina to Missouri with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Missouri?

I’m not ready to book a flight from South Carolina to Missouri right now. Can momondo alert me if prices change?

An easier way to manage your Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Missouri

Popular cities in Missouri

Popular flights according to clicks in the last 7 days on momondo