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Cheap flights from South Carolina to Gainesville from $248

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Gainesville departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Gainesville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:45 pm - 12:25 am
CLT
-
GNV
1h 40mnonstop
American Airlines Logo
7:01 pm - 8:55 pm
GNV
-
CLT
1h 54mnonstop
$325American Airlines
Sat, Feb 21 - Wed, Feb 25
Delta Logo
5:40 am - 9:29 am
GSP
-
GNV
3h 49m
1 stop
Delta Logo
4:59 pm - 8:33 pm
GNV
-
GSP
3h 34m
1 stop
$327Delta
Fri, Apr 3 - Mon, Apr 6
American Airlines Logo
10:45 pm - 12:25 am
CLT
-
GNV
1h 40mnonstop
American Airlines Logo
7:01 pm - 8:55 pm
GNV
-
CLT
1h 54mnonstop
$333American Airlines
Wed, Mar 11 - Tue, Mar 17
American Airlines Logo
10:45 pm - 12:25 am
CLT
-
GNV
1h 40mnonstop
American Airlines Logo
6:00 am - 1:36 pm
GNV
-
CLT
7h 36m
1 stop
$335American Airlines
Sat, Feb 21 - Wed, Feb 25
Delta Logo
5:40 am - 9:24 am
GSP
-
GNV
3h 44m
1 stop
Delta Logo
7:00 pm - 11:54 pm
GNV
-
GSP
4h 54m
1 stop
$337Delta
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
7:20 pm - 11:59 pm
CLT
-
GNV
4h 39m
1 stop
American Airlines Logo
4:54 pm - 6:44 pm
GNV
-
CLT
1h 50mnonstop
$343American Airlines
Wed, Mar 11 - Tue, Mar 17
Delta Logo
6:59 pm - 10:36 pm
CLT
-
GNV
3h 37m
1 stop
Delta Logo
7:00 pm - 11:49 pm
GNV
-
CLT
4h 49m
1 stop
$345Delta
Sat, Feb 21 - Wed, Feb 25
Delta Logo
5:40 am - 9:24 am
GSP
-
GNV
3h 44m
1 stop
Delta Logo
7:00 pm - 11:43 pm
GNV
-
GSP
4h 43m
1 stop
$347Delta
Fri, Feb 27 - Thu, Mar 5
Delta Logo
5:30 am - 9:29 am
CLT
-
GNV
3h 59m
1 stop
Delta Logo
4:59 pm - 8:18 pm
GNV
-
CLT
3h 19m
1 stop
$353Delta
Wed, Mar 11 - Tue, Mar 17
American Airlines Logo
8:45 pm - 10:27 pm
CLT
-
GNV
1h 42mnonstop
American Airlines Logo
7:45 pm - 9:39 pm
GNV
-
CLT
1h 54mnonstop
$364American Airlines
Sat, Apr 4 - Mon, Apr 6

Delta flights from South Carolina to Gainesville

Our best Delta deals on South Carolina to Gainesville flight tickets
Delta
Apr 3
GSP5:40 amGreenville
3h 49m
1 stop
GNV9:29 amGainesville Regional
Apr 6
GNV4:59 pmGainesville Regional
3h 34m
1 stop
GSP8:33 pmGreenville
$327
Delta
Mar 5
GSP5:40 amGreenville
3h 44m
1 stop
GNV9:24 amGainesville Regional
Mar 9
GNV7:00 pmGainesville Regional
4h 54m
1 stop
GSP11:54 pmGreenville
$337
Delta
Feb 21
CLT6:59 pmCharlotte Douglas
3h 37m
1 stop
GNV10:36 pmGainesville Regional
Feb 25
GNV7:00 pmGainesville Regional
4h 49m
1 stop
CLT11:49 pmCharlotte Douglas
$345

American Airlines flights from South Carolina to Gainesville

Our best American Airlines deals on South Carolina to Gainesville flight tickets
American Airlines
Feb 21
CLT10:45 pmCharlotte Douglas
1h 40m
GNV12:25 amGainesville Regional
Feb 25
GNV7:01 pmGainesville Regional
1h 54m
CLT8:55 pmCharlotte Douglas
$325
American Airlines
Mar 11
CLT10:45 pmCharlotte Douglas
1h 40m
GNV12:25 amGainesville Regional
Mar 17
GNV7:01 pmGainesville Regional
1h 54m
CLT8:55 pmCharlotte Douglas
$333
American Airlines
Feb 21
CLT10:45 pmCharlotte Douglas
1h 40m
GNV12:25 amGainesville Regional
Feb 25
GNV6:00 amGainesville Regional
7h 36m
1 stop
CLT1:36 pmCharlotte Douglas
$335

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from South Carolina to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Sat 2/21

10:45 pm-12:25 am

Nonstop1h 40m

Gainesville Regional

Wed 2/25

7:01 pm-8:55 pm

Nonstop1h 54m

$325

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 4/3

5:40 am-9:29 am

1 stop3h 49m

Gainesville Regional

Mon 4/6

4:59 pm-8:33 pm

1 stop3h 34m

$327

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Wed 3/11

10:45 pm-12:25 am

Nonstop1h 40m

Gainesville Regional

Tue 3/17

7:01 pm-8:55 pm

Nonstop1h 54m

$333

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Sat 2/21

10:45 pm-12:25 am

Nonstop1h 40m

Gainesville Regional

Wed 2/25

6:00 am-1:36 pm

1 stop7h 36m

$335

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Thu 3/5

5:40 am-9:24 am

1 stop3h 44m

Gainesville Regional

Mon 3/9

7:00 pm-11:54 pm

1 stop4h 54m

$337

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Wed 3/11

7:20 pm-11:59 pm

1 stop4h 39m

Gainesville Regional

Tue 3/17

4:54 pm-6:44 pm

Nonstop1h 50m

$343

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Sat 2/21

6:59 pm-10:36 pm

1 stop3h 37m

Gainesville Regional

Wed 2/25

7:00 pm-11:49 pm

1 stop4h 49m

$345

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 2/27

5:40 am-9:24 am

1 stop3h 44m

Gainesville Regional

Thu 3/5

7:00 pm-11:43 pm

1 stop4h 43m

$347

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Wed 3/11

5:30 am-9:29 am

1 stop3h 59m

Gainesville Regional

Tue 3/17

4:59 pm-8:18 pm

1 stop3h 19m

$353

CharlotteGainesville

CLT - GNV

CLTGNV

Charlotte Douglas

Sat 4/4

8:45 pm-10:27 pm

Nonstop1h 42m

Gainesville Regional

Mon 4/6

7:45 pm-9:39 pm

Nonstop1h 54m

$364

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Gainesville from

How to get the cheapest flight ticket from South Carolina to Gainesville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from South Carolina to Gainesville Regional?

American Airlines and Delta are the most popular carriers operating from South Carolina to Gainesville Regional

What airlines fly to Gainesville?

American Airlines, Spirit Airlines and Allegiant Air are the top three most popular airlines that fly to Gainesville from South Carolina according to our data. American Airlines is the first choice among our users, with 31% of people opting to fly with this airline when traveling to Gainesville. Keep in mind that there are 6 different airlines that fly to Gainesville on a routine basis, so you have a few additional options to choose from.

Cheap South Carolina to Gainesville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Gainesville

Fastest flight time

1h 40m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun

Airports in Gainesville

1 airport
The fastest flight from South Carolina to Gainesville takes 1h 40m
Direct flights go from South Carolina to Gainesville on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Gainesville. From South Carolina there are direct flights to Gainesville Regional (GNV).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Gainesville Regional Airport?

    Prices for flights from South Carolina to Gainesville Regional Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Gainesville Regional Airport?

  • How old do you have to be to fly from South Carolina to Gainesville Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Gainesville Regional Airport.

  • What documentation or ID do you need to fly to Gainesville Regional Airport?

    The travel and health documents you'll need for your trip to Gainesville Regional Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Gainesville Regional Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Gainesville

Compare and see reviews for airlines that fly from South Carolina to Gainesville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $296Free CancellationRating
7.9
8,173 reviews
Search Delta flights

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua
Trenton

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Gainesville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Gainesville for you.

Can I find flights from South Carolina to Gainesville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Gainesville flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Gainesville?

Once you have performed a search for South Carolina to Gainesville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Gainesville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Gainesville, momondo offers a useful price alert feature which will track prices for flights to Gainesville from South Carolina and alert you when they change.

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