How many flights depart from South America to Indiana on average per week?

26 flights are operational weekly from South America to Indiana as of February 2026. The most popular departure day for this route is Mon, with 15% of flights per week taking off on this day.

What is the cheapest airline that flies from South America to Indiana?

Volaris, Spirit Airlines, and Arajet are the most popular carriers operating from South America to Indiana

What airlines fly to Indiana?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to Indiana from South America according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Indiana. Keep in mind that there are 4 different airlines that fly to Indiana on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South America to Indiana?

Prices for flights from South America to Indiana are updated daily.

How many operators does momondo search for flights from South America to Indiana?

As of February 2026, there are 7 operators available to choose from for flights from South America to Indiana.

How old do you have to be to fly from South America to Indiana?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South America to Indiana.

What documentation or ID do you need to fly to Indiana?

The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$179 Cheap Flights from South America to Indiana in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from South America to Indiana

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:11 am - 9:17 pm

MDE

ORD

20h 06m

1 stop

1:27 pm - 12:16 am

ORD

MDE

10h 49m

1 stop

$291Multiple Airlines

Fri, May 1 - Wed, May 6

11:59 pm - 10:54 pm

GYE

ORD

22h 55m

1 stop

5:34 pm - 11:04 pm

ORD

GYE

29h 30m

1 stop

$293Multiple Airlines

Thu, Apr 16 - Wed, Apr 29

3:15 pm - 11:47 pm

MDE

ORD

9h 32m

1 stop

5:05 am - 12:21 am

ORD

MDE

19h 16m

1 stop

$298Spirit Airlines

Sat, Mar 7 - Tue, Mar 17

11:59 pm - 7:47 pm

GYE

ORD

19h 48m

1 stop

7:06 am - 11:04 pm

ORD

GYE

15h 58m

1 stop

$299Spirit Airlines

Thu, Apr 16 - Wed, Apr 29

7:00 am - 11:17 pm

MDE

ORD

16h 17m

1 stop

6:00 am - 10:39 pm

ORD

MDE

16h 39m

1 stop

$317American Airlines

Mon, Mar 9 - Tue, Mar 17

7:00 am - 11:17 pm

MDE

ORD

16h 17m

1 stop

8:10 am - 8:10 pm

ORD

MDE

12h 00m

2 stops

$322American Airlines

Mon, Mar 9 - Tue, Mar 17

8:40 am - 9:09 pm

BOG

MDW

12h 29m

2 stops

10:35 am - 12:05 pm

MDW

BOG

25h 30m

2 stops

$330Delta

Sat, May 9 - Tue, Jul 28

8:30 am - 1:27 am

BOG

ORD

16h 57m

1 stop

12:00 pm - 10:00 pm

ORD

BOG

10h 00m

1 stop

$330United Airlines

Fri, May 1 - Tue, May 12

9:00 am - 10:31 pm

BOG

MDW

13h 31m

1 stop

6:00 am - 4:45 pm

MDW

BOG

10h 45m

2 stops

$332Delta

Tue, Mar 17 - Tue, Mar 24

7:25 am - 10:05 am

UIO

ORD

26h 40m

1 stop

6:30 am - 5:00 am

ORD

UIO

22h 30m

1 stop

$353United Airlines

Mon, May 4 - Mon, May 25

Spirit Airlines flights from South America to Indiana

Our best Spirit Airlines deals on South America to Indiana flight tickets

Spirit Airlines

Mar 5

MDE3:15 pmMedellín Jose Maria Cordova Intl

9h 32m

1 stop

ORD11:47 pmChicago O'Hare Intl

Mar 10

ORD5:15 amChicago O'Hare Intl

7h 58m

1 stop

MDE1:13 pmMedellín Jose Maria Cordova Intl

$256

Spirit Airlines

Mar 7

MDE3:15 pmMedellín Jose Maria Cordova Intl

9h 32m

1 stop

ORD11:47 pmChicago O'Hare Intl

Mar 17

ORD5:05 amChicago O'Hare Intl

19h 16m

1 stop

MDE12:21 amMedellín Jose Maria Cordova Intl

$298

Spirit Airlines

Apr 16

GYE11:59 pmGuayaquil Jose Joaquin de Olmedo

19h 48m

1 stop

ORD7:47 pmChicago O'Hare Intl

Apr 29

ORD7:06 amChicago O'Hare Intl

15h 58m

1 stop

GYE11:04 pmGuayaquil Jose Joaquin de Olmedo

$299

American Airlines flights from South America to Indiana

Our best American Airlines deals on South America to Indiana flight tickets

American Airlines

Mar 9

MDE7:00 amMedellín Jose Maria Cordova Intl

16h 17m

1 stop

ORD11:17 pmChicago O'Hare Intl

Mar 17

ORD6:00 amChicago O'Hare Intl

16h 39m

1 stop

MDE10:39 pmMedellín Jose Maria Cordova Intl

$317

American Airlines

Mar 9

MDE7:00 amMedellín Jose Maria Cordova Intl

16h 17m

1 stop

ORD11:17 pmChicago O'Hare Intl

Mar 17

ORD8:10 amChicago O'Hare Intl

12h 00m

2 stops

MDE8:10 pmMedellín Jose Maria Cordova Intl

$322

American Airlines

Jun 10

MDE6:00 amMedellín Jose Maria Cordova Intl

15h 29m

1 stop

ORD9:29 pmChicago O'Hare Intl

Aug 26

ORD2:55 pmChicago O'Hare Intl

8h 40m

1 stop

MDE11:35 pmMedellín Jose Maria Cordova Intl

$329

Fly from

Fly to

Route

Depart

Return

Price

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Fri 5/1

1:11 am-9:17 pm

1 stop20h 06m

Chicago O'Hare Intl

Wed 5/6

1:27 pm-12:16 am

1 stop10h 49m

$291

GuayaquilChicago

GYE - ORD

GYEORD

Guayaquil Jose Joaquin de Olmedo

Thu 4/16

11:59 pm-10:54 pm

1 stop22h 55m

Chicago O'Hare Intl

Wed 4/29

5:34 pm-11:04 pm

1 stop29h 30m

$293

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Sat 3/7

3:15 pm-11:47 pm

1 stop9h 32m

Chicago O'Hare Intl

Tue 3/17

5:05 am-12:21 am

1 stop19h 16m

$298

GuayaquilChicago

GYE - ORD

GYEORD

Guayaquil Jose Joaquin de Olmedo

Thu 4/16

11:59 pm-7:47 pm

1 stop19h 48m

Chicago O'Hare Intl

Wed 4/29

7:06 am-11:04 pm

1 stop15h 58m

$299

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Mon 3/9

7:00 am-11:17 pm

1 stop16h 17m

Chicago O'Hare Intl

Tue 3/17

6:00 am-10:39 pm

1 stop16h 39m

$317

MedellínChicago

MDE - ORD

MDEORD

Medellín Jose Maria Cordova Intl

Mon 3/9

7:00 am-11:17 pm

1 stop16h 17m

Chicago O'Hare Intl

Tue 3/17

8:10 am-8:10 pm

2 stops12h 00m

$322

BogotáChicago

BOG - MDW

BOGMDW

Bogotá El Dorado

Sat 5/9

8:40 am-9:09 pm

2 stops12h 29m

Chicago Midway

Tue 7/28

10:35 am-12:05 pm

2 stops25h 30m

$330

BogotáChicago

BOG - ORD

BOGORD

Bogotá El Dorado

Fri 5/1

8:30 am-1:27 am

1 stop16h 57m

Chicago O'Hare Intl

Tue 5/12

12:00 pm-10:00 pm

1 stop10h 00m

$330

BogotáChicago

BOG - MDW

BOGMDW

Bogotá El Dorado

Tue 3/17

9:00 am-10:31 pm

1 stop13h 31m

Chicago Midway

Tue 3/24

6:00 am-4:45 pm

2 stops10h 45m

$332

QuitoChicago

UIO - ORD

UIOORD

Quito Mariscal Sucr

Mon 5/4

7:25 am-10:05 am

1 stop26h 40m

Chicago O'Hare Intl

Mon 5/25

6:30 am-5:00 am

1 stop22h 30m

$353

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South America to Indiana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Indiana?

The cheapest month to fly to Indiana from South America is in February. Flight prices, which tend to average around $716, are often lower during this time because this is during the off-season. The month of March is another great option to travel to Indiana, with average flight prices from South America averaging around $729.

Can stopping save me money on South America to Indiana flights?

You could potentially save up to 26% on your flight if you consider stops on a South America to Indiana flight.

Cheap South America to Indiana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South America to Indiana

Fastest flight time	6h 15m
Direct flights	Every day
Airports in Indiana	94 airports

The fastest flight from South America to Indiana takes 6h 15m

Direct flights go from South America to Indiana every day.

There are 94 airports in Indiana. From South America there are direct flights to Chicago O'Hare Intl (ORD).

Search flight deals

When did momondo last update prices for flights from South America to Indiana?
Prices for flights from South America to Indiana are updated daily.
How many operators does momondo search for flights from South America to Indiana?
As of February 2026, there are 7 operators available to choose from for flights from South America to Indiana.
How old do you have to be to fly from South America to Indiana?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South America to Indiana.
What documentation or ID do you need to fly to Indiana?
The necessary travel and health documents for your Indiana trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South America to Indiana

Compare and see reviews for airlines that fly from South America to Indiana with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $358	Free Cancellation	Rating 6.3 8,492 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $477	Free Cancellation	Rating 7.2 11,353 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $833	Free Cancellation	Rating 7.5 1,919 reviews	Search LATAM Airlines flights
Delta	PriceFrom $885	Free Cancellation	Rating 7.9 8,238 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from South America to Indiana?

Finding the right flight to Indiana from South America is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Indiana quick and easy, saving you time and money.

Can I find flights from South America to Indiana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Indiana from South America with this policy.

How can momondo help me find flights from South America to Indiana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indiana from South America.

I’m not ready to book a flight from South America to Indiana right now. Can momondo alert me if prices change?

Price alerts on flights to Indiana from South America are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.