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Cheap flights from Sioux Falls to Myrtle Beach from $242

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Myrtle Beach departing on 4/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Sioux Falls to Myrtle Beach

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:11 pm - 4:31 pm
FSD
-
MYR
21h 20m
1 stop
Multiple Airlines Logo
9:58 am - 5:21 pm
MYR
-
FSD
8h 23m
1 stop
$242Multiple Airlines
Mon, Apr 20 - Fri, Apr 24
Multiple Airlines Logo
6:11 pm - 11:29 pm
FSD
-
MYR
28h 18m
1 stop
Multiple Airlines Logo
9:58 am - 5:21 pm
MYR
-
FSD
8h 23m
1 stop
$281Multiple Airlines
Fri, Apr 24 - Mon, Apr 27
Multiple Airlines Logo
6:11 pm - 11:29 pm
FSD
-
MYR
28h 18m
1 stop
Multiple Airlines Logo
3:53 pm - 5:21 pm
MYR
-
FSD
26h 28m
2 stops
$292Multiple Airlines
Fri, May 1 - Sun, May 10
United Airlines Logo
5:00 am - 5:13 pm
FSD
-
MYR
11h 13m
2 stops
United Airlines Logo
3:14 pm - 9:52 pm
MYR
-
FSD
7h 38m
1 stop
$296United Airlines
Tue, May 5 - Tue, May 12
American Airlines Logo
1:41 pm - 11:02 pm
FSD
-
MYR
8h 21m
2 stops
American Airlines Logo
10:33 am - 7:09 pm
MYR
-
FSD
9h 36m
2 stops
$301American Airlines
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
6:11 pm - 7:38 pm
FSD
-
MYR
24h 27m
2 stops
Multiple Airlines Logo
9:58 am - 5:21 pm
MYR
-
FSD
8h 23m
1 stop
$316Multiple Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
12:25 pm - 11:40 pm
FSD
-
MYR
10h 15m
2 stops
American Airlines Logo
5:07 pm - 12:27 am
MYR
-
FSD
8h 20m
1 stop
$344American Airlines
Thu, Aug 27 - Mon, Aug 31
Delta Logo
8:05 am - 3:06 pm
FSD
-
MYR
6h 01m
1 stop
Delta Logo
6:11 pm - 11:40 pm
MYR
-
FSD
6h 29m
1 stop
$369Delta
Tue, Apr 21 - Sat, Apr 25
Delta Logo
1:44 pm - 12:14 am
FSD
-
MYR
9h 30m
2 stops
Delta Logo
6:11 pm - 11:40 pm
MYR
-
FSD
6h 29m
1 stop
$374Delta
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
1:41 pm - 11:02 pm
FSD
-
MYR
8h 21m
2 stops
American Airlines Logo
5:00 am - 12:57 pm
MYR
-
FSD
8h 57m
2 stops
$379American Airlines
Tue, Apr 21 - Sat, Apr 25

American Airlines flights from Sioux Falls to Myrtle Beach

Our best American Airlines deals on Sioux Falls to Myrtle Beach flight tickets
American Airlines
May 5
FSD1:41 pmSioux Falls Joe Foss Field
8h 21m
2 stops
MYR11:02 pmMyrtle Beach Intl
May 12
MYR10:33 amMyrtle Beach Intl
9h 36m
2 stops
FSD7:09 pmSioux Falls Joe Foss Field
$301
American Airlines
Aug 27
FSD12:25 pmSioux Falls Joe Foss Field
10h 15m
2 stops
MYR11:40 pmMyrtle Beach Intl
Aug 31
MYR5:07 pmMyrtle Beach Intl
8h 20m
1 stop
FSD12:27 amSioux Falls Joe Foss Field
$344
American Airlines
Apr 21
FSD1:41 pmSioux Falls Joe Foss Field
8h 21m
2 stops
MYR11:02 pmMyrtle Beach Intl
Apr 25
MYR5:00 amMyrtle Beach Intl
8h 57m
2 stops
FSD12:57 pmSioux Falls Joe Foss Field
$379

United Airlines flights from Sioux Falls to Myrtle Beach

Our best United Airlines deals on Sioux Falls to Myrtle Beach flight tickets
United Airlines
May 5
FSD5:00 amSioux Falls Joe Foss Field
11h 13m
2 stops
MYR5:13 pmMyrtle Beach Intl
May 12
MYR3:14 pmMyrtle Beach Intl
7h 38m
1 stop
FSD9:52 pmSioux Falls Joe Foss Field
$296
United Airlines
Apr 28
FSD7:39 amSioux Falls Joe Foss Field
5h 38m
1 stop
MYR2:17 pmMyrtle Beach Intl
May 2
MYR3:14 pmMyrtle Beach Intl
7h 38m
1 stop
FSD9:52 pmSioux Falls Joe Foss Field
$381
United Airlines
Apr 28
FSD6:10 amSioux Falls Joe Foss Field
9h 52m
2 stops
MYR5:02 pmMyrtle Beach Intl
May 2
MYR3:14 pmMyrtle Beach Intl
7h 38m
1 stop
FSD9:52 pmSioux Falls Joe Foss Field
$386

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Sioux Falls to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Mon 4/20

6:11 pm-4:31 pm

1 stop21h 20m

Myrtle Beach Intl

Fri 4/24

9:58 am-5:21 pm

1 stop8h 23m

$242

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 4/24

6:11 pm-11:29 pm

1 stop28h 18m

Myrtle Beach Intl

Mon 4/27

9:58 am-5:21 pm

1 stop8h 23m

$281

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 5/1

6:11 pm-11:29 pm

1 stop28h 18m

Myrtle Beach Intl

Sun 5/10

3:53 pm-5:21 pm

2 stops26h 28m

$292

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 5/5

5:00 am-5:13 pm

2 stops11h 13m

Myrtle Beach Intl

Tue 5/12

3:14 pm-9:52 pm

1 stop7h 38m

$296

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 5/5

1:41 pm-11:02 pm

2 stops8h 21m

Myrtle Beach Intl

Tue 5/12

10:33 am-7:09 pm

2 stops9h 36m

$301

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 4/24

6:11 pm-7:38 pm

2 stops24h 27m

Myrtle Beach Intl

Mon 4/27

9:58 am-5:21 pm

1 stop8h 23m

$316

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Thu 8/27

12:25 pm-11:40 pm

2 stops10h 15m

Myrtle Beach Intl

Mon 8/31

5:07 pm-12:27 am

1 stop8h 20m

$344
Quickest round-trip

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 4/21

8:05 am-3:06 pm

1 stop6h 01m

Myrtle Beach Intl

Sat 4/25

6:11 pm-11:40 pm

1 stop6h 29m

$369

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 4/21

1:44 pm-12:14 am

2 stops9h 30m

Myrtle Beach Intl

Sat 4/25

6:11 pm-11:40 pm

1 stop6h 29m

$374

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 4/21

1:41 pm-11:02 pm

2 stops8h 21m

Myrtle Beach Intl

Sat 4/25

5:00 am-12:57 pm

2 stops8h 57m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Sioux Falls to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Sioux Falls and Myrtle Beach?

Can stopping save me money on Sioux Falls to Myrtle Beach flights?

You could potentially save up to 73% on your flight if you consider stops on a Sioux Falls to Myrtle Beach flight.

When to book flights from Sioux Falls to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Myrtle Beach (FSD to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Myrtle Beach

Fastest flight time

5h 35m

Direct flights

None
The fastest flight from Sioux Falls to Myrtle Beach takes 5h 35m
There are no direct flights from Sioux Falls to Myrtle Beach. There are no popular flight routes from Sioux Falls to Myrtle Beach.
Search flight deals

Frequently asked questions about flying from Sioux Falls to Myrtle Beach

  • How far is Sioux Falls Joe Foss Field to Myrtle Beach Intl by plane?

    Sioux Falls Joe Foss Field and Myrtle Beach Intl are 1174.8 mi apart from one another. In terms of flight time, this usually takes a little over 5h 35m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport refresh daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The travel and health documents required for your trip to Myrtle Beach Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Myrtle Beach Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Sioux Falls to Myrtle Beach?

Best airlines flying from Sioux Falls to Myrtle Beach

Compare and see reviews for airlines that fly from Sioux Falls to Myrtle Beach with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $256Free CancellationRating
7.1
11,548 reviews
Search American Airlines flights
DeltaPriceFrom $272Free CancellationRating
7.9
8,388 reviews
Search Delta flights

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Sunset Beach
Ocean Isle Beach
Murrells Inlet
Garden City Beach
Surfside Beach
Conway
Little River
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Myrtle Beach?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Sioux Falls to Myrtle Beach. momondo saves you time and could save you money on your trip.

Can I find flights from Sioux Falls to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Sioux Falls to Myrtle Beach flights to just show those with flexible booking policies.

How can momondo help me find flights from Sioux Falls to Myrtle Beach?

Once you have performed a search for Sioux Falls to Myrtle Beach flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Myrtle Beach right now. Can momondo alert me if prices change?

Price alerts on flights to Myrtle Beach from Sioux Falls are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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