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Cheap flights from Sioux Falls to Myrtle Beach from $345

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Myrtle Beach departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:26 pm - 8:54 pm
FSD
-
MYR
7h 28m2 stops
American Airlines Logo
8:00 am - 5:45 pm
MYR
-
FSD
10h 45m2 stops
$345American Airlines
Wed, Jan 21 - Sun, Jan 25
American Airlines Logo
2:06 pm - 11:55 pm
FSD
-
MYR
8h 49m2 stops
American Airlines Logo
12:16 pm - 7:10 pm
MYR
-
FSD
7h 54m1 stop
$354American Airlines
Fri, Mar 13 - Wed, Mar 18
American Airlines Logo
2:06 pm - 11:55 pm
FSD
-
MYR
8h 49m2 stops
American Airlines Logo
6:00 am - 1:36 pm
MYR
-
FSD
8h 36m2 stops
$360American Airlines
Fri, Mar 13 - Wed, Mar 18
Delta Logo
5:00 am - 3:12 pm
FSD
-
MYR
9h 12m2 stops
Delta Logo
6:54 pm - 11:10 pm
MYR
-
FSD
5h 16m1 stop
$389Delta
Wed, Jan 21 - Sun, Jan 25
American Airlines Logo
6:00 am - 4:59 pm
FSD
-
MYR
9h 59m2 stops
American Airlines Logo
12:05 pm - 9:35 pm
MYR
-
FSD
10h 30m2 stops
$396American Airlines
Wed, Feb 4 - Sun, Feb 8
Multiple Airlines Logo
2:35 pm - 10:05 am
FSD
-
MYR
18h 30m2 stops
Multiple Airlines Logo
10:00 am - 5:21 pm
MYR
-
FSD
8h 21m1 stop
$415Multiple Airlines
Wed, May 6 - Mon, May 11
American Airlines Logo
1:26 pm - 10:50 pm
FSD
-
MYR
8h 24m2 stops
American Airlines Logo
12:16 pm - 7:10 pm
MYR
-
FSD
7h 54m1 stop
$464American Airlines
Sat, Mar 14 - Wed, Mar 18
American Airlines Logo
1:26 pm - 10:50 pm
FSD
-
MYR
8h 24m2 stops
American Airlines Logo
6:00 am - 1:36 pm
MYR
-
FSD
8h 36m2 stops
$470American Airlines
Sat, Mar 14 - Wed, Mar 18
Multiple Airlines Logo
5:55 pm - 8:55 pm
FSD
-
MYR
26h 00m1 stop
Multiple Airlines Logo
6:37 pm - 5:05 pm
MYR
-
FSD
23h 28m1 stop
$504Multiple Airlines
Fri, Mar 13 - Sun, Mar 22
American Airlines Logo
7:42 pm - 11:11 am
FSD
-
MYR
14h 29m1 stop
American Airlines Logo
12:16 pm - 10:55 pm
MYR
-
FSD
11h 39m1 stop
$520American Airlines
Fri, Mar 13 - Wed, Mar 18

United Airlines flights from Sioux Falls to Myrtle Beach

Our best United Airlines deals on Sioux Falls to Myrtle Beach flight tickets
United Airlines
Jan 20
FSD7:30 amSioux Falls Joe Foss Field
28h 11m
2 stops
MYR12:41 pmMyrtle Beach Intl
Jan 24
MYR1:13 pmMyrtle Beach Intl
9h 37m
2 stops
FSD9:50 pmSioux Falls Joe Foss Field
$603
Find similar
United Airlines
Jan 20
FSD7:30 amSioux Falls Joe Foss Field
28h 11m
2 stops
MYR12:41 pmMyrtle Beach Intl
Jan 24
MYR1:13 pmMyrtle Beach Intl
9h 37m
2 stops
FSD9:50 pmSioux Falls Joe Foss Field
$628
Find similar
United Airlines
Mar 13
FSD7:43 amSioux Falls Joe Foss Field
27h 33m
2 stops
MYR12:16 pmMyrtle Beach Intl
Mar 18
MYR12:57 pmMyrtle Beach Intl
32h 47m
3 stops
FSD8:44 pmSioux Falls Joe Foss Field
$1,022
Find similar

American Airlines flights from Sioux Falls to Myrtle Beach

Our best American Airlines deals on Sioux Falls to Myrtle Beach flight tickets
American Airlines
Jan 21
FSD12:26 pmSioux Falls Joe Foss Field
7h 28m
2 stops
MYR8:54 pmMyrtle Beach Intl
Jan 25
MYR8:00 amMyrtle Beach Intl
10h 45m
2 stops
FSD5:45 pmSioux Falls Joe Foss Field
$345
Find similar
American Airlines
Mar 13
FSD2:06 pmSioux Falls Joe Foss Field
8h 49m
2 stops
MYR11:55 pmMyrtle Beach Intl
Mar 18
MYR12:16 pmMyrtle Beach Intl
7h 54m
1 stop
FSD7:10 pmSioux Falls Joe Foss Field
$354
Find similar
American Airlines
Mar 13
FSD2:06 pmSioux Falls Joe Foss Field
8h 49m
2 stops
MYR11:55 pmMyrtle Beach Intl
Mar 18
MYR6:00 amMyrtle Beach Intl
8h 36m
2 stops
FSD1:36 pmSioux Falls Joe Foss Field
$360
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Sioux Falls to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 1/21

12:26 pm-8:54 pm

2 stops7h 28m

Myrtle Beach Intl

Sun 1/25

8:00 am-5:45 pm

2 stops10h 45m

$345

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 3/13

2:06 pm-11:55 pm

2 stops8h 49m

Myrtle Beach Intl

Wed 3/18

12:16 pm-7:10 pm

1 stop7h 54m

$354

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 3/13

2:06 pm-11:55 pm

2 stops8h 49m

Myrtle Beach Intl

Wed 3/18

6:00 am-1:36 pm

2 stops8h 36m

$360

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 1/21

5:00 am-3:12 pm

2 stops9h 12m

Myrtle Beach Intl

Sun 1/25

6:54 pm-11:10 pm

1 stop5h 16m

$389

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 2/4

6:00 am-4:59 pm

2 stops9h 59m

Myrtle Beach Intl

Sun 2/8

12:05 pm-9:35 pm

2 stops10h 30m

$396

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 5/6

2:35 pm-10:05 am

2 stops18h 30m

Myrtle Beach Intl

Mon 5/11

10:00 am-5:21 pm

1 stop8h 21m

$415

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 3/14

1:26 pm-10:50 pm

2 stops8h 24m

Myrtle Beach Intl

Wed 3/18

12:16 pm-7:10 pm

1 stop7h 54m

$464

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 3/14

1:26 pm-10:50 pm

2 stops8h 24m

Myrtle Beach Intl

Wed 3/18

6:00 am-1:36 pm

2 stops8h 36m

$470

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 3/13

5:55 pm-8:55 pm

1 stop26h 00m

Myrtle Beach Intl

Sun 3/22

6:37 pm-5:05 pm

1 stop23h 28m

$504

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 3/13

7:42 pm-11:11 am

1 stop14h 29m

Myrtle Beach Intl

Wed 3/18

12:16 pm-10:55 pm

1 stop11h 39m

$520

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Sioux Falls to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Sioux Falls to Myrtle Beach flights?

You could potentially save up to 73% on your flight if you consider stops on a Sioux Falls to Myrtle Beach flight.

When to book flights from Sioux Falls to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Myrtle Beach (FSD to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Myrtle Beach

Fastest flight time

7h 24m

Direct flights

None
The fastest flight from Sioux Falls to Myrtle Beach takes 7h 24m
There are no direct flights from Sioux Falls to Myrtle Beach. There are no popular flight routes from Sioux Falls to Myrtle Beach.
Search flight deals

  • How far is Sioux Falls Joe Foss Field to Myrtle Beach Intl by plane?

    Sioux Falls Joe Foss Field and Myrtle Beach Intl are 1174.8 mi apart from one another. In terms of flight time, this usually takes a little over 7h 24m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport refresh daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Sioux Falls Joe Foss Field Airport to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The travel and health documents required for your trip to Myrtle Beach Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Myrtle Beach Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Sioux Falls to Myrtle Beach?

Best airlines flying from Sioux Falls to Myrtle Beach

Compare and see reviews for airlines that fly from Sioux Falls to Myrtle Beach with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $258Free CancellationRating
7.9
8,022 reviews
Search Delta flights
American AirlinesPriceFrom $261Free CancellationRating
7.2
11,088 reviews
Search American Airlines flights
United AirlinesPriceFrom $273Free CancellationRating
7.4
9,138 reviews
Search United Airlines flights

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Sunset Beach
Ocean Isle Beach
Murrells Inlet
Garden City Beach
Surfside Beach
Conway
Little River
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Myrtle Beach?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Sioux Falls to Myrtle Beach. momondo saves you time and could save you money on your trip.

Can I find flights from Sioux Falls to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Sioux Falls to Myrtle Beach flights to just show those with flexible booking policies.

How can momondo help me find flights from Sioux Falls to Myrtle Beach?

Once you have performed a search for Sioux Falls to Myrtle Beach flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Myrtle Beach right now. Can momondo alert me if prices change?

Price alerts on flights to Myrtle Beach from Sioux Falls are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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