Which airlines fly to Santa Cruz de la Sierra?

When flying to Santa Cruz de la Sierra from United States, momondo travelers will most often fly with one of these popular airlines: Copa Airlines, Avianca, BoA or United Airlines. Depending on what airport in United States you fly from, you may be able to find flights with any of these popular airlines.

Copa Airlines Flights to Santa Cruz de la Sierra

The most popular airline for flights to Santa Cruz de la Sierra on momondo is Copa Airlines, which operates 5 flights in this direction every week. Most depart out of Panama City Tocumen Intl, with the best deal for Copa Airlines flights to Santa Cruz de la Sierra being $269 (round-trip, Boston Logan Intl to Santa Cruz de la Sierra, momondo searches within the last 72 hours). In 1,546 Copa Airlines reviews, it is rated 7.6 by momondo users.

United Airlines Flights to Santa Cruz de la Sierra

$319 is the best round-trip United Airlines deal to Santa Cruz de la Sierra found on momondo in the last few days. The deal departed from Boston Logan Intl. United Airlines has 5 flights to Santa Cruz de la Sierra most weeks, with prices varying by availability. 10,194 momondo users have reviewed United Airlines, scoring the airline a 7.4/10 on average.

How long does it take to fly to Santa Cruz de la Sierra?

If you’re flying from a popular airport in United States, such as Los Angeles or Miami, and flying into Santa Cruz de la Sierra, then you can expect flight times to average 14h 25m and 6h 50m, respectively.

$260 Cheap Flights to Santa Cruz de la Sierra in 2026

Flights to Santa Cruz de la Sierra Viru Viru Intl

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Find the cheapest flights from the United States to Santa Cruz de la Sierra

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:10 pm - 2:40 amFLL Fort Lauderdale-VVI Santa Cruz de la Sierra Viru Viru Intl

11h 30m1 stop Bogotá El Dorado

3:45 am - 5:35 pmVVI Santa Cruz de la Sierra Viru Viru Intl-FLL Fort Lauderdale

14h 50m1 stop Bogotá El Dorado

$548Avianca

Wed, Nov 4 - Tue, Nov 17

2:10 pm - 2:40 amFLL Fort Lauderdale-VVI Santa Cruz de la Sierra Viru Viru Intl

11h 30m1 stop Bogotá El Dorado

3:45 am - 5:35 pmVVI Santa Cruz de la Sierra Viru Viru Intl-FLL Fort Lauderdale

14h 50m1 stop Bogotá El Dorado

$548Avianca

Wed, Nov 11 - Sat, Nov 14

2:13 pm - 3:37 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

11h 24m1 stop Panama City Tocumen Intl

11:49 am - 12:46 pmVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

26h 57m1 stop Panama City Tocumen Intl

$568Copa Airlines

Sun, Nov 15 - Mon, Nov 23

5:40 am - 10:44 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

17h 04m1 stop Panama City Tocumen Intl

1:08 am - 9:21 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

21h 13m1 stop Panama City Tocumen Intl

$574Copa Airlines

Thu, Oct 29 - Tue, Nov 3

10:10 am - 5:00 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

11:35 pm - 6:25 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$593BoA

Tue, Oct 6 - Wed, Oct 7

10:10 am - 5:00 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

11:35 pm - 6:25 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$594BoA

Tue, Oct 6 - Sun, Oct 11

12:50 pm - 10:38 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

32h 48m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:42 am - 10:16 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

35h 34m3 stops Panama City Tocumen Intl Chicago O'Hare Intl Newark

$594United Airlines

Thu, Nov 26 - Mon, Dec 7

12:50 pm - 10:38 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

32h 48m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:42 am - 3:12 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

28h 30m2 stops Panama City Tocumen Intl Chicago O'Hare Intl

$594United Airlines

Thu, Nov 26 - Mon, Dec 7

5:00 am - 3:37 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

20h 37m2 stops Newark Panama City Tocumen Intl

3:45 am - 11:17 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

33h 32m2 stops Bogotá El Dorado Houston George Bush Intcntl

$612Multiple Airlines

Sun, Nov 15 - Sun, Nov 22

7:37 pm - 10:44 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

50h 07m2 stops Atlanta Hartsfield-Jackson Panama City Tocumen Intl

3:35 am - 12:23 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

21h 48m2 stops Bogotá El Dorado Houston George Bush Intcntl

$629Multiple Airlines

Mon, Sep 21 - Sun, Oct 11

Cheap last minute flights

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12:25 pm - 10:44 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

10h 19m1 stop Panama City Tocumen Intl

1:12 am - 10:48 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

21h 36m1 stop Panama City Tocumen Intl

$576Copa Airlines

Mon, Sep 14 - Sun, Sep 20

8:25 am - 10:44 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

14h 19m1 stop Panama City Tocumen Intl

11:47 am - 10:48 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

11h 01m1 stop Panama City Tocumen Intl

$578Copa Airlines

Sat, Sep 12 - Thu, Sep 24

10:10 am - 5:00 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

11:35 pm - 6:25 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$584BoA

Mon, Sep 14 - Mon, Sep 21

5:37 pm - 10:44 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

53h 07m2 stops Newark Panama City Tocumen Intl

11:47 am - 11:54 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

24h 07m2 stops Panama City Tocumen Intl Chicago O'Hare Intl

$594United Airlines

Mon, Sep 14 - Mon, Sep 21

10:10 am - 5:00 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

11:35 pm - 6:25 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$595BoA

Tue, Sep 15 - Wed, Oct 7

5:37 pm - 10:44 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

53h 07m2 stops Newark Panama City Tocumen Intl

11:47 am - 11:54 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

24h 07m2 stops Panama City Tocumen Intl Chicago O'Hare Intl

$595United Airlines

Mon, Sep 14 - Mon, Sep 21

8:15 am - 2:30 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 15m1 stop Bogotá El Dorado

3:35 am - 12:25 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

8h 50m1 stop Bogotá El Dorado

$632Avianca

Tue, Sep 15 - Sat, Sep 26

8:15 am - 2:30 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 15m1 stop Bogotá El Dorado

3:35 am - 12:25 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

8h 50m1 stop Bogotá El Dorado

$632Avianca

Thu, Sep 17 - Tue, Sep 29

8:50 am - 2:30 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

16h 40m2 stops Houston George Bush Intcntl Bogotá El Dorado

11:47 am - 7:55 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

45h 08m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$667Multiple Airlines

Sat, Sep 12 - Mon, Sep 14

12:51 am - 2:30 amLAX Los Angeles-VVI Santa Cruz de la Sierra Viru Viru Intl

22h 39m2 stops Houston George Bush Intcntl Bogotá El Dorado

11:55 am - 1:07 pmVVI Santa Cruz de la Sierra Viru Viru Intl-LAX Los Angeles

28h 12m2 stops Panama City Tocumen Intl Chicago O'Hare Intl

$751Multiple Airlines

Sat, Sep 12 - Mon, Oct 26

Fly from

Route

Depart

Return

Price

Cheapest round-trip

Fort LauderdaleSanta Cruz de la Sierra

FLL Fort Lauderdale - VVI Santa Cruz de la Sierra Viru Viru Intl

FLLVVI

Fort Lauderdale

Wed 11/4

2:10 pm-2:40 am

1 stop11h 30m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/17

3:45 am-5:35 pm

1 stop14h 50m

$548

Fort LauderdaleSanta Cruz de la Sierra

FLL Fort Lauderdale - VVI Santa Cruz de la Sierra Viru Viru Intl

FLLVVI

Fort Lauderdale

Wed 11/11

2:10 pm-2:40 am

1 stop11h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/14

3:45 am-5:35 pm

1 stop14h 50m

$548

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sun 11/15

2:13 pm-3:37 am

1 stop11h 24m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/23

11:49 am-12:46 pm

1 stop26h 57m

$568

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 10/29

5:40 am-10:44 pm

1 stop17h 04m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/3

1:08 am-9:21 pm

1 stop21h 13m

$574

Quickest round-trip

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Tue 10/6

10:10 am-5:00 pm

Nonstop6h 50m

Santa Cruz de la Sierra Viru Viru Intl

Wed 10/7

11:35 pm-6:25 am

Nonstop6h 50m

$593

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Tue 10/6

10:10 am-5:00 pm

Nonstop6h 50m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/11

11:35 pm-6:25 am

Nonstop6h 50m

$594

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 11/26

12:50 pm-10:38 pm

2 stops32h 48m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/7

11:42 am-10:16 pm

3 stops35h 34m

$594

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 11/26

12:50 pm-10:38 pm

2 stops32h 48m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/7

11:42 am-3:12 pm

2 stops28h 30m

$594

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sun 11/15

5:00 am-3:37 am

2 stops20h 37m

Santa Cruz de la Sierra Viru Viru Intl

Sun 11/22

3:45 am-11:17 am

2 stops33h 32m

$612

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Mon 9/21

7:37 pm-10:44 pm

2 stops50h 07m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/11

3:35 am-12:23 am

2 stops21h 48m

$629

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

Santa Cruz de la Sierra flights insights and trends

Explore insights for your Santa Cruz de la Sierra flight to craft the best travel plan

Prices

Other information

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from United States is in October. Flight prices, which tend to average around $625, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in October, then you should wait until February to fly from United States, when ticket prices are also cheap, with an average price of $640.

What is the absolute cheapest flight to Santa Cruz de la Sierra?

See prices from:

How far in advance should I book a flight to Santa Cruz de la Sierra?

You are more likely to see cheaper flights to Santa Cruz de la Sierra from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Cruz de la Sierra for around $769 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Cruz de la Sierra from United States for as low as $613 on momondo.

Cheapest flights to Santa Cruz de la Sierra Viru Viru Intl

Find the cheapest flights to Santa Cruz de la Sierra Viru Viru Intl from your nearest city or airport

Find flights from Los Angeles to Santa Cruz de la Sierra

CHEAPEST MONTH TO FLY TO SANTA CRUZ DE LA SIERRA FROM LOS ANGELES	November	21% cheaper	Flying from Los Angeles to Santa Cruz de la Sierra costs on average just $631 in November
MOST EXPENSIVE MONTH TO FLY TO SANTA CRUZ DE LA SIERRA FROM LOS ANGELES	December	36% more expensive	It costs about $1,084 for flights to Santa Cruz de la Sierra from Los Angeles in December
MOST POPULAR MONTH TO FLY TO SANTA CRUZ DE LA SIERRA FROM LOS ANGELES	July	440% more users visited	More momondo users searched in flights to Santa Cruz de la Sierra from Los Angeles in July than any other month

Cheap Santa Cruz de la Sierra flight deals and tips

Summary info about Santa Cruz de la Sierra flight prices, duration and airlines

Best One-Way Price	$260
Best Round-Trip Price	$548
Fastest flight time	10h 49m
Popular in	December

The best one-way flight price to Santa Cruz de la Sierra from United States in the last 5 days is $260 (Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl).

Search Deals

The best round-trip flight price to Santa Cruz de la Sierra from United States in the last 5 days is $548 (Fort Lauderdale to Santa Cruz de la Sierra Viru Viru Intl).

Search Deals

The fastest flight to Santa Cruz de la Sierra from United States takes 10h 49m (Baltimore/Washington to Santa Cruz de la Sierra Viru Viru Intl).

Search Deals

December has the highest demand for flights to Santa Cruz de la Sierra, with a 17% price increase on average.

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Frequently asked questions about flying to Santa Cruz de la Sierra

How far in advance should I book a flight to Santa Cruz de la Sierra?

Most flyers found that booking tickets 9 days in advance of their planned departure date is the best time to get cheap flights to Santa Cruz de la Sierra. During this timeframe, flight prices are around $811. Keep in mind that you might also find cheap flights to Santa Cruz de la Sierra outside of this time window. In fact, momondo users recently found flights from United States to Santa Cruz de la Sierra for $232.

When did momondo last update prices for flights to Santa Cruz de la Sierra Viru Viru Intl Airport?

Prices for flights to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

How many operators does momondo search for flights to Santa Cruz de la Sierra Viru Viru Intl Airport?

As of September 2026, there are 11 operators available to choose from for flights to Santa Cruz de la Sierra Viru Viru Intl Airport.

How old do you have to be to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel to Santa Cruz de la Sierra Viru Viru Intl Airport.

What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal to Santa Cruz de la Sierra?

It is quick and easy to find flights to Santa Cruz de la Sierra on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights to Santa Cruz de la Sierra with flexible booking policies on momondo?

All flight searches to Santa Cruz de la Sierra on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra and alert you when they change.