Which airlines fly to Santa Cruz de la Sierra?

When flying to Santa Cruz de la Sierra from United States, momondo travelers will most often fly with one of these popular airlines: Copa Airlines, Avianca, BoA or United Airlines. Depending on what airport in United States you fly from, you may be able to find flights with any of these popular airlines.

Copa Airlines Flights to Santa Cruz de la Sierra

The most popular airline for flights to Santa Cruz de la Sierra on momondo is Copa Airlines, which operates 8 flights in this direction every week. Most depart out of Panama City Tocumen Intl, with the best deal for Copa Airlines flights to Santa Cruz de la Sierra being $312 (round-trip, Boston Logan Intl to Santa Cruz de la Sierra, momondo searches within the last 72 hours). In 1,557 Copa Airlines reviews, it is rated 7.6 by momondo users.

United Airlines Flights to Santa Cruz de la Sierra

$319 is the best round-trip United Airlines deal to Santa Cruz de la Sierra found on momondo in the last few days. The deal departed from Boston Logan Intl. United Airlines has 8 flights to Santa Cruz de la Sierra most weeks, with prices varying by availability. 10,107 momondo users have reviewed United Airlines, scoring the airline a 7.4/10 on average.

How long does it take to fly to Santa Cruz de la Sierra?

If you’re flying from a popular airport in United States, such as Los Angeles Los Angeles or San Francisco, and flying into Santa Cruz de la Sierra, then you can expect flight times to average 22h 40m and 18h 06m, respectively.

$260 Cheap Flights to Santa Cruz de la Sierra in 2026

Flights to Santa Cruz de la Sierra Viru Viru Intl

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Find the cheapest flights from the United States to Santa Cruz de la Sierra

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:35 am - 10:38 pmORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

13h 03m1 stop Panama City Tocumen Intl

11:49 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

14h 22m1 stop Panama City Tocumen Intl

$568Copa Airlines

Sat, Nov 14 - Tue, Nov 24

7:35 am - 3:37 amORD Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 02m1 stop Panama City Tocumen Intl

1:08 am - 12:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl

25h 03m1 stop Panama City Tocumen Intl

$568Copa Airlines

Sun, Nov 1 - Mon, Nov 16

12:15 am - 4:35 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

28h 20m1 stop Lima J Chavez Intl

5:30 am - 6:10 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

25h 40m1 stop Lima J Chavez Intl

$589LATAM Airlines

Fri, Oct 23 - Sun, Nov 1

12:15 am - 4:35 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

28h 20m1 stop Lima J Chavez Intl

5:30 am - 7:10 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

25h 40m1 stop Lima J Chavez Intl

$589LATAM Airlines

Fri, Oct 23 - Sat, Oct 31

2:00 pm - 2:30 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

12h 30m1 stop Bogotá El Dorado

3:35 am - 12:25 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

8h 50m1 stop Bogotá El Dorado

$594Avianca

Thu, Sep 3 - Mon, Sep 14

8:15 am - 2:30 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 15m1 stop Bogotá El Dorado

3:35 am - 6:05 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

14h 30m1 stop Bogotá El Dorado

$594Avianca

Thu, Sep 3 - Mon, Sep 14

8:45 am - 10:38 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

36h 53m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:42 am - 5:35 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

30h 53m3 stops Panama City Tocumen Intl Chicago O'Hare Intl Newark

$594United Airlines

Thu, Nov 26 - Mon, Dec 7

8:45 am - 10:38 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

36h 53m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

11:42 am - 6:05 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

31h 23m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$594United Airlines

Thu, Nov 26 - Mon, Dec 7

10:10 am - 6:00 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

8:35 am - 2:25 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$595BoA

Mon, Nov 16 - Fri, Dec 4

8:00 pm - 3:50 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

11:35 pm - 5:25 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$595BoA

Thu, Nov 26 - Mon, Dec 7

Cheap last minute flights

Enter your travel dates to find the best prices.

8:28 am - 10:40 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

14h 12m1 stop Panama City Tocumen Intl

1:12 am - 1:47 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

24h 35m1 stop Panama City Tocumen Intl

$592Copa Airlines

Tue, Aug 18 - Thu, Aug 20

12:24 pm - 10:40 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

10h 16m1 stop Panama City Tocumen Intl

1:12 am - 12:18 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

11h 06m1 stop Panama City Tocumen Intl

$592Copa Airlines

Fri, Aug 21 - Thu, Aug 27

11:26 am - 10:40 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

35h 14m2 stops Newark Panama City Tocumen Intl

11:47 am - 11:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

23h 24m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$603United Airlines

Tue, Aug 18 - Thu, Aug 27

8:45 am - 10:40 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

37h 55m2 stops Newark Panama City Tocumen Intl

11:47 am - 11:11 amVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

23h 24m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$612United Airlines

Tue, Aug 18 - Thu, Aug 27

10:10 am - 5:00 pmMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

8:35 am - 3:25 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$615BoA

Sat, Aug 22 - Fri, Aug 28

9:00 pm - 3:50 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

6h 50mnonstop

8:35 am - 3:25 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

6h 50mnonstop

$621BoA

Fri, Aug 21 - Fri, Aug 28

2:00 pm - 2:30 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

12h 30m1 stop Bogotá El Dorado

3:35 am - 11:30 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

19h 55m1 stop Bogotá El Dorado

$630Avianca

Thu, Aug 20 - Sat, Aug 29

5:05 pm - 2:30 amMIA Miami-VVI Santa Cruz de la Sierra Viru Viru Intl

9h 25m1 stop Bogotá El Dorado

3:35 am - 11:30 pmVVI Santa Cruz de la Sierra Viru Viru Intl-MIA Miami

19h 55m1 stop Bogotá El Dorado

$630Avianca

Thu, Aug 20 - Mon, Aug 24

7:40 pm - 10:40 pmEWR Newark-VVI Santa Cruz de la Sierra Viru Viru Intl

27h 00m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

1:12 am - 4:04 pmVVI Santa Cruz de la Sierra Viru Viru Intl-EWR Newark

14h 52m1 stop Panama City Tocumen Intl

$902Multiple Airlines

Tue, Aug 18 - Thu, Sep 17

11:51 pm - 10:40 pmEWR Newark-VVI Santa Cruz de la Sierra Viru Viru Intl

22h 49m1 stop Panama City Tocumen Intl

1:12 am - 4:04 pmVVI Santa Cruz de la Sierra Viru Viru Intl-EWR Newark

14h 52m1 stop Panama City Tocumen Intl

$914Multiple Airlines

Tue, Aug 18 - Thu, Sep 17

Fly from

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sat 11/14

7:35 am-10:38 pm

1 stop13h 03m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/24

11:49 am-12:11 am

1 stop14h 22m

$568

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sun 11/1

7:35 am-3:37 am

1 stop18h 02m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/16

1:08 am-12:11 am

1 stop25h 03m

$568

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Fri 10/23

12:15 am-4:35 am

1 stop28h 20m

Santa Cruz de la Sierra Viru Viru Intl

Sun 11/1

5:30 am-6:10 am

1 stop25h 40m

$589

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Fri 10/23

12:15 am-4:35 am

1 stop28h 20m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/31

5:30 am-7:10 am

1 stop25h 40m

$589

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 9/3

2:00 pm-2:30 am

1 stop12h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/14

3:35 am-12:25 pm

1 stop8h 50m

$594

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 9/3

8:15 am-2:30 am

1 stop18h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/14

3:35 am-6:05 pm

1 stop14h 30m

$594

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 11/26

8:45 am-10:38 pm

2 stops36h 53m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/7

11:42 am-5:35 pm

3 stops30h 53m

$594

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 11/26

8:45 am-10:38 pm

2 stops36h 53m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/7

11:42 am-6:05 pm

2 stops31h 23m

$594

Quickest round-trip

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Mon 11/16

10:10 am-6:00 pm

Nonstop6h 50m

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/4

8:35 am-2:25 pm

Nonstop6h 50m

$595

MiamiSanta Cruz de la Sierra

MIA Miami - VVI Santa Cruz de la Sierra Viru Viru Intl

MIAVVI

Miami

Thu 11/26

8:00 pm-3:50 am

Nonstop6h 50m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/7

11:35 pm-5:25 am

Nonstop6h 50m

$595

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

Santa Cruz de la Sierra flights insights and trends

Explore insights for your Santa Cruz de la Sierra flight to craft the best travel plan

Prices

Other information

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from United States is in October. Flight prices, which tend to average around $576, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in October, then you should wait until February to fly from United States, when ticket prices are also cheap, with an average price of $640.

What is the absolute cheapest flight to Santa Cruz de la Sierra?

See prices from:

How far in advance should I book a flight to Santa Cruz de la Sierra?

You are more likely to see cheaper flights to Santa Cruz de la Sierra from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Cruz de la Sierra for around $746 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Cruz de la Sierra from United States for as low as $613 on momondo.

Cheapest flights to Santa Cruz de la Sierra Viru Viru Intl

Find the cheapest flights to Santa Cruz de la Sierra Viru Viru Intl from your nearest city or airport

Find flights from Los Angeles to Santa Cruz de la Sierra

CHEAPEST MONTH TO FLY TO SANTA CRUZ DE LA SIERRA FROM LOS ANGELES	September	23% cheaper	Flying from Los Angeles to Santa Cruz de la Sierra costs on average just $604 in September
MOST EXPENSIVE MONTH TO FLY TO SANTA CRUZ DE LA SIERRA FROM LOS ANGELES	December	35% more expensive	It costs about $1,057 for flights to Santa Cruz de la Sierra from Los Angeles in December
MOST POPULAR MONTH TO FLY TO SANTA CRUZ DE LA SIERRA FROM LOS ANGELES	July	440% more users visited	More momondo users searched in flights to Santa Cruz de la Sierra from Los Angeles in July than any other month

Cheap Santa Cruz de la Sierra flight deals and tips

Summary info about Santa Cruz de la Sierra flight prices, duration and airlines

Best One-Way Price	$260
Best Round-Trip Price	$568
Fastest flight time	11h 18m
Popular in	December

The best one-way flight price to Santa Cruz de la Sierra from United States in the last 5 days is $260 (Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl).

Search Deals

The best round-trip flight price to Santa Cruz de la Sierra from United States in the last 5 days is $568 (Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl).

Search Deals

The fastest flight to Santa Cruz de la Sierra from United States takes 11h 18m (Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl).

Search Deals

December has the highest demand for flights to Santa Cruz de la Sierra, with a 17% price increase on average.

Search Deals

Frequently asked questions about flying to Santa Cruz de la Sierra

How far in advance should I book a flight to Santa Cruz de la Sierra?

Most flyers found that booking tickets 9 days in advance of their planned departure date is the best time to get cheap flights to Santa Cruz de la Sierra. During this timeframe, flight prices are around $783. Keep in mind that you might also find cheap flights to Santa Cruz de la Sierra outside of this time window. In fact, momondo users recently found flights from United States to Santa Cruz de la Sierra for $232.

When did momondo last update prices for flights to Santa Cruz de la Sierra Viru Viru Intl Airport?

Prices for flights to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

How many operators does momondo search for flights to Santa Cruz de la Sierra Viru Viru Intl Airport?

As of August 2026, there are 11 operators available to choose from for flights to Santa Cruz de la Sierra Viru Viru Intl Airport.

How old do you have to be to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel to Santa Cruz de la Sierra Viru Viru Intl Airport.

What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal to Santa Cruz de la Sierra?

It is quick and easy to find flights to Santa Cruz de la Sierra on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights to Santa Cruz de la Sierra with flexible booking policies on momondo?

All flight searches to Santa Cruz de la Sierra on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra and alert you when they change.