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Cheap flights from Charlotte to Santa Cruz de la Sierra from $372

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Santa Cruz de la Sierra departing on 10/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Charlotte to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:00 am - 10:44 pmCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 44m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
United Airlines Logo
11:47 am - 9:15 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
33h 28m2 stops Panama City Tocumen Intl Newark
$783United Airlines
Mon, Oct 12 - Mon, Oct 19
Copa Airlines Logo
6:00 am - 10:44 pmCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 44m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
Copa Airlines Logo
11:55 am - 11:22 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
23h 27m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$787Copa Airlines
Sun, Oct 25 - Sat, Oct 31
Copa Airlines Logo
7:50 pm - 3:40 amCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
31h 50m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
Copa Airlines Logo
1:12 am - 11:22 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
34h 10m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$793Copa Airlines
Sat, Oct 24 - Fri, Oct 30
United Airlines Logo
6:00 am - 3:38 amCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
21h 38m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
United Airlines Logo
11:47 am - 10:08 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
22h 21m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$843United Airlines
Sun, Oct 4 - Tue, Oct 6
Copa Airlines Logo
7:55 pm - 3:38 amCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
31h 43m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
Copa Airlines Logo
11:47 am - 9:44 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
21h 57m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$863Copa Airlines
Sat, Sep 5 - Sat, Sep 12
Multiple Airlines Logo
8:10 am - 3:40 amCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
19h 30m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
Multiple Airlines Logo
3:40 am - 11:59 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
20h 19m2 stops Bogotá El Dorado Washington, D.C. Dulles Intl
$981Multiple Airlines
Mon, Oct 26 - Thu, Oct 29
Multiple Airlines Logo
1:59 pm - 5:00 pmCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
27h 01m1 stop Miami
Multiple Airlines Logo
11:35 pm - 6:51 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
43h 16m2 stops Miami Denver Intl
$996Multiple Airlines
Mon, Oct 12 - Mon, Oct 19
Copa Airlines Logo
6:00 am - 10:48 pmCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
15h 48m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
Copa Airlines Logo
11:42 am - 8:55 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
34h 13m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$1,113Copa Airlines
Thu, Dec 10 - Thu, Dec 24
Multiple Airlines Logo
12:34 pm - 10:48 pmCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
33h 14m2 stops Miami Panama City Tocumen Intl
Multiple Airlines Logo
11:35 pm - 11:39 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
13h 04m1 stop Miami
$1,145Multiple Airlines
Thu, Dec 10 - Wed, Dec 23
Multiple Airlines Logo
12:34 pm - 3:50 amCLT  Charlotte Douglas-VVI Santa Cruz de la Sierra Viru Viru Intl
14h 16m1 stop Miami
Multiple Airlines Logo
11:42 am - 11:39 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLT Charlotte Douglas
24h 57m2 stops Panama City Tocumen Intl Miami
$1,150Multiple Airlines
Fri, Dec 11 - Wed, Dec 23

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Copa Airlines flights from Charlotte to Santa Cruz de la Sierra

Our best Copa Airlines deals on Charlotte to Santa Cruz de la Sierra flight tickets
Copa Airlines
Oct 25
CLT6:00 amCharlotte Douglas
16h 44m
2 stops
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 31
VVI11:55 amSanta Cruz de la Sierra Viru Viru Intl
23h 27m
2 stops
CLT11:22 amCharlotte Douglas
$787
Copa Airlines
Oct 24
CLT7:50 pmCharlotte Douglas
31h 50m
2 stops
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
Oct 30
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
34h 10m
2 stops
CLT11:22 amCharlotte Douglas
$793
Copa Airlines
Sep 5
CLT7:55 pmCharlotte Douglas
31h 43m
2 stops
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
Sep 12
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
21h 57m
2 stops
CLT9:44 amCharlotte Douglas
$863

United Airlines flights from Charlotte to Santa Cruz de la Sierra

Our best United Airlines deals on Charlotte to Santa Cruz de la Sierra flight tickets
United Airlines
Oct 12
CLT6:00 amCharlotte Douglas
16h 44m
2 stops
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 19
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
33h 28m
2 stops
CLT9:15 pmCharlotte Douglas
$783
United Airlines
Oct 4
CLT6:00 amCharlotte Douglas
21h 38m
2 stops
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
Oct 6
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
22h 21m
2 stops
CLT10:08 amCharlotte Douglas
$843
United Airlines
Dec 11
CLT4:05 pmCharlotte Douglas
29h 43m
2 stops
VVI10:48 pmSanta Cruz de la Sierra Viru Viru Intl
Dec 23
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
24h 06m
2 stops
CLT10:48 amCharlotte Douglas
$1,418

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Charlotte to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Mon 10/12

6:00 am-10:44 pm

2 stops16h 44m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/19

11:47 am-9:15 pm

2 stops33h 28m

$783

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Sun 10/25

6:00 am-10:44 pm

2 stops16h 44m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/31

11:55 am-11:22 am

2 stops23h 27m

$787

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Sat 10/24

7:50 pm-3:40 am

2 stops31h 50m

Santa Cruz de la Sierra Viru Viru Intl

Fri 10/30

1:12 am-11:22 am

2 stops34h 10m

$793

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Sun 10/4

6:00 am-3:38 am

2 stops21h 38m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/6

11:47 am-10:08 am

2 stops22h 21m

$843

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Sat 9/5

7:55 pm-3:38 am

2 stops31h 43m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/12

11:47 am-9:44 am

2 stops21h 57m

$863

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Mon 10/26

8:10 am-3:40 am

2 stops19h 30m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/29

3:40 am-11:59 pm

2 stops20h 19m

$981

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Mon 10/12

1:59 pm-5:00 pm

1 stop27h 01m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/19

11:35 pm-6:51 pm

2 stops43h 16m

$996

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Thu 12/10

6:00 am-10:48 pm

2 stops15h 48m

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/24

11:42 am-8:55 pm

2 stops34h 13m

$1,113

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Thu 12/10

12:34 pm-10:48 pm

2 stops33h 14m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/23

11:35 pm-11:39 am

1 stop13h 04m

$1,145
Quickest round-trip

CharlotteSanta Cruz de la Sierra

CLT Charlotte Douglas - VVI Santa Cruz de la Sierra Viru Viru Intl

CLTVVI

Charlotte Douglas

Fri 12/11

12:34 pm-3:50 am

1 stop14h 16m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/23

11:42 am-11:39 am

2 stops24h 57m

$1,150

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Charlotte to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Charlotte Douglas to Santa Cruz de la Sierra Viru Viru Intl?

United Airlines is the most popular carrier operating from Charlotte Douglas to Santa Cruz de la Sierra Viru Viru Intl

When to book flights from Charlotte to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Santa Cruz de la Sierra (CLT to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Santa Cruz de la Sierra

Fastest flight time

14h 16m

Direct flights

None
The fastest flight from Charlotte to Santa Cruz de la Sierra takes 14h 16m
There are no direct flights from Charlotte to Santa Cruz de la Sierra. There are no popular flight routes from Charlotte to Santa Cruz de la Sierra.
Search flight deals

Frequently asked questions about flying from Charlotte to Santa Cruz de la Sierra

  • How far is Charlotte Douglas to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The distance between Charlotte Douglas and Santa Cruz de la Sierra Viru Viru Intl is about 3841.0 mi. A reasonable flight in good conditions will take 14h 16m.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Charlotte Douglas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport refresh daily.

  • How old do you have to be to fly from Charlotte Douglas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Santa Cruz de la Sierra?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Charlotte to Santa Cruz de la Sierra. momondo saves you time and could save you money on your trip.

Can I find flights from Charlotte to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. All flights to Santa Cruz de la Sierra from Charlotte on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Charlotte to Santa Cruz de la Sierra?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Cruz de la Sierra from Charlotte.

I’m not ready to book a flight from Charlotte to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Cruz de la Sierra from Charlotte. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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