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Cheap flights from Houston to Santa Cruz de la Sierra from $369

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santa Cruz de la Sierra departing on 8/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Houston to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:20 am - 3:38 amIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
19h 18m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:47 am - 10:23 amVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
23h 36m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$843United Airlines
Mon, Sep 7 - Mon, Sep 21
United Airlines Logo
6:18 pm - 10:44 pmIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
27h 26m2 stops Denver Intl Panama City Tocumen Intl
United Airlines Logo
11:47 am - 11:30 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
36h 43m2 stops Panama City Tocumen Intl Newark
$843United Airlines
Mon, Sep 7 - Mon, Sep 21
United Airlines Logo
8:35 pm - 10:44 pmIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
25h 09m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:47 am - 9:19 amVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
22h 32m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$843United Airlines
Mon, Sep 7 - Mon, Sep 21
Avianca Logo
1:00 pm - 2:35 amIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
35h 35m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
3:40 am - 3:10 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
13h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$861Avianca
Tue, Nov 10 - Thu, Nov 19
Multiple Airlines Logo
10:05 pm - 3:37 amIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
27h 32m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
Multiple Airlines Logo
1:08 am - 8:08 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
21h 00m1 stop Panama City Tocumen Intl
$883Multiple Airlines
Tue, Nov 10 - Thu, Nov 19
Multiple Airlines Logo
7:00 am - 3:50 amIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
19h 50m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
11:35 pm - 6:57 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
20h 22m2 stops Miami Charlotte Douglas
$884Multiple Airlines
Sat, Oct 17 - Sun, Oct 18
Copa Airlines Logo
10:03 am - 10:44 pmIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
11h 41m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:47 am - 7:56 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
33h 09m1 stop Panama City Tocumen Intl
$892Copa Airlines
Mon, Sep 7 - Mon, Sep 21
Copa Airlines Logo
10:03 am - 10:44 pmIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
11h 41m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:12 am - 2:17 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
14h 05m1 stop Panama City Tocumen Intl
$892Copa Airlines
Mon, Sep 7 - Sun, Sep 20
Avianca Logo
5:45 pm - 2:30 amIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
31h 45m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
3:35 am - 4:10 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
13h 35m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$894Avianca
Fri, Sep 11 - Sat, Sep 19
Avianca Logo
5:45 pm - 2:30 amIAH  Houston George Bush Intcntl-VVI Santa Cruz de la Sierra Viru Viru Intl
31h 45m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
3:35 am - 4:10 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-IAH Houston George Bush Intcntl
37h 35m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$912Avianca
Mon, Aug 17 - Tue, Aug 25

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United Airlines flights from Houston to Santa Cruz de la Sierra

Our best United Airlines deals on Houston to Santa Cruz de la Sierra flight tickets
United Airlines
Sep 7
IAH6:18 pmHouston George Bush Intcntl
27h 26m
2 stops
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Sep 21
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
36h 43m
2 stops
IAH11:30 pmHouston George Bush Intcntl
$843
United Airlines
Dec 10
IAH9:55 pmHouston George Bush Intcntl
46h 53m
2 stops
VVI10:48 pmSanta Cruz de la Sierra Viru Viru Intl
Dec 30
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
25h 22m
2 stops
IAH11:04 amHouston George Bush Intcntl
$1,022
United Airlines
Dec 10
IAH9:55 pmHouston George Bush Intcntl
46h 53m
2 stops
VVI10:48 pmSanta Cruz de la Sierra Viru Viru Intl
Dec 30
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
10h 26m
1 stop
IAH8:08 pmHouston George Bush Intcntl
$1,098

Avianca flights from Houston to Santa Cruz de la Sierra

Our best Avianca deals on Houston to Santa Cruz de la Sierra flight tickets
Avianca
Nov 10
IAH1:00 pmHouston George Bush Intcntl
35h 35m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Nov 19
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
13h 30m
2 stops
IAH3:10 pmHouston George Bush Intcntl
$861
Avianca
Aug 9
IAH5:45 pmHouston George Bush Intcntl
31h 45m
2 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Aug 17
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
37h 35m
2 stops
IAH4:10 pmHouston George Bush Intcntl
$887
Avianca
Aug 10
IAH2:05 pmHouston George Bush Intcntl
35h 25m
2 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Aug 21
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
13h 35m
2 stops
IAH4:10 pmHouston George Bush Intcntl
$894

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Houston to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Mon 9/7

7:20 am-3:38 am

2 stops19h 18m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/21

11:47 am-10:23 am

2 stops23h 36m

$843

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Mon 9/7

6:18 pm-10:44 pm

2 stops27h 26m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/21

11:47 am-11:30 pm

2 stops36h 43m

$843

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Mon 9/7

8:35 pm-10:44 pm

2 stops25h 09m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/21

11:47 am-9:19 am

2 stops22h 32m

$843

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Tue 11/10

1:00 pm-2:35 am

2 stops35h 35m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/19

3:40 am-3:10 pm

2 stops13h 30m

$861

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Tue 11/10

10:05 pm-3:37 am

2 stops27h 32m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/19

1:08 am-8:08 pm

1 stop21h 00m

$883

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Sat 10/17

7:00 am-3:50 am

2 stops19h 50m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/18

11:35 pm-6:57 pm

2 stops20h 22m

$884

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Mon 9/7

10:03 am-10:44 pm

1 stop11h 41m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/21

11:47 am-7:56 pm

1 stop33h 09m

$892
Quickest round-trip

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Mon 9/7

10:03 am-10:44 pm

1 stop11h 41m

Santa Cruz de la Sierra Viru Viru Intl

Sun 9/20

1:12 am-2:17 pm

1 stop14h 05m

$892

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Fri 9/11

5:45 pm-2:30 am

2 stops31h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/19

3:35 am-4:10 pm

2 stops13h 35m

$894

HoustonSanta Cruz de la Sierra

IAH Houston George Bush Intcntl - VVI Santa Cruz de la Sierra Viru Viru Intl

IAHVVI

Houston George Bush Intcntl

Mon 8/17

5:45 pm-2:30 am

2 stops31h 45m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/25

3:35 am-4:10 pm

2 stops37h 35m

$912

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Houston to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from Houston is in October. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in October, then you should wait until March to fly from Houston, when ticket prices are also cheap, with an average price of $766.

Cheap Houston to Santa Cruz de la Sierra flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santa Cruz de la Sierra

Fastest flight time

19h 50m

Direct flights

None
The fastest flight from Houston to Santa Cruz de la Sierra takes 19h 50m
There are no direct flights from Houston to Santa Cruz de la Sierra. There are no popular flight routes from Houston to Santa Cruz de la Sierra.
Search flight deals

Frequently asked questions about flying from Houston to Santa Cruz de la Sierra

  • How far is Houston to Santa Cruz de la Sierra Viru Viru Intl by plane?

    Houston and Santa Cruz de la Sierra Viru Viru Intl are 3922.1 mi apart from one another. By plane, this route typically takes 19h 50m.

  • When did momondo last update prices for flights from Houston to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Houston to Santa Cruz de la Sierra Viru Viru Intl Airport are updated daily.

  • How many operators does momondo search for flights from Houston to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Houston to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Houston to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The travel and health documents you'll need for your trip to Santa Cruz de la Sierra Viru Viru Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Houston to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $709Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $726Free CancellationRating
7.4
10,072 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santa Cruz de la Sierra?

Finding the right flight to Santa Cruz de la Sierra from Houston is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Cruz de la Sierra quick and easy, saving you time and money.

Can I find flights from Houston to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. All flights to Santa Cruz de la Sierra from Houston on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Houston to Santa Cruz de la Sierra?

Once you have performed a search for Houston to Santa Cruz de la Sierra flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santa Cruz de la Sierra flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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