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Cheap flights from San Francisco to Santa Cruz de la Sierra from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santa Cruz de la Sierra departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:15 pm - 10:46 pmSFO-VVI
26h 31m2 stops
United Airlines Logo
11:40 am - 7:24 amVVI-SFO
23h 44m2 stops
$638United Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 24
Copa Airlines Logo
12:36 am - 3:36 amSFO-VVI
23h 00m1 stop
Copa Airlines Logo
11:40 am - 11:17 pmVVI-SFO
15h 37m1 stop
$671Copa Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
United Airlines Logo
12:43 am - 10:46 pmSFO-VVI
18h 03m2 stops
United Airlines Logo
11:40 am - 9:05 pmVVI-SFO
37h 25m2 stops
$675United Airlines
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Fri, Nov 28 - Sat, Dec 6
Avianca Logo
1:35 am - 2:35 amSFO-VVI
21h 00m2 stops
Avianca Logo
3:40 am - 11:20 pmVVI-SFO
23h 40m2 stops
$696Avianca
Find Deal
Sat, Feb 7 - Fri, Feb 13
Avianca Logo
11:10 pm - 2:35 amSFO-VVI
47h 25m2 stops
Avianca Logo
3:40 am - 11:20 pmVVI-SFO
23h 40m2 stops
$701Avianca
Find Deal
Sun, Feb 8 - Fri, Feb 13
United Airlines Logo
12:45 am - 10:50 pmSFO-VVI
19h 05m2 stops
United Airlines Logo
11:44 am - 10:19 amVVI-SFO
25h 35m2 stops
$712United Airlines
Find Deal
Sat, Apr 4 - Tue, Apr 7
United Airlines Logo
7:10 pm - 3:36 amSFO-VVI
28h 26m2 stops
United Airlines Logo
11:40 am - 7:26 pmVVI-SFO
35h 46m2 stops
$770United Airlines
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Sun, Nov 30 - Sat, Dec 6
LATAM Airlines Logo
8:25 am - 4:35 amSFO-VVI
40h 10m2 stops
LATAM Airlines Logo
10:43 am - 11:29 amVVI-SFO
28h 46m2 stops
$815LATAM Airlines
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Mon, Dec 1 - Sun, Dec 7
Copa Airlines Logo
1:42 am - 10:50 pmSFO-VVI
18h 08m1 stop
Copa Airlines Logo
1:15 am - 11:40 pmVVI-SFO
25h 25m1 stop
$821Copa Airlines
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Sat, Apr 4 - Mon, Apr 6
LATAM Airlines Logo
10:39 am - 4:35 amSFO-VVI
37h 56m2 stops
LATAM Airlines Logo
11:15 am - 9:44 amVVI-SFO
26h 29m2 stops
$980LATAM Airlines
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Sun, Nov 30 - Sat, Dec 6

United Airlines flights from San Francisco to Santa Cruz de la Sierra

Our best United Airlines deals on San Francisco to Santa Cruz de la Sierra flight tickets
United Airlines
Nov 13
SFO4:15 pmSan Francisco
26h 31m
2 stops
VVI10:46 pmSanta Cruz de la Sierra Viru Viru Intl
Nov 24
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
23h 44m
2 stops
SFO7:24 amSan Francisco
$638
Find similar
United Airlines
Nov 5
SFO4:56 pmSan Francisco
25h 50m
2 stops
VVI10:46 pmSanta Cruz de la Sierra Viru Viru Intl
Nov 17
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
25h 56m
2 stops
SFO9:36 amSan Francisco
$645
Find similar
United Airlines
Nov 28
SFO12:43 amSan Francisco
18h 03m
2 stops
VVI10:46 pmSanta Cruz de la Sierra Viru Viru Intl
Dec 6
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
37h 25m
2 stops
SFO9:05 pmSan Francisco
$675
Find similar

Copa Airlines flights from San Francisco to Santa Cruz de la Sierra

Our best Copa Airlines deals on San Francisco to Santa Cruz de la Sierra flight tickets
Copa Airlines
Nov 29
SFO12:36 amSan Francisco
23h 00m
1 stop
VVI3:36 amSanta Cruz de la Sierra Viru Viru Intl
Dec 6
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
15h 37m
1 stop
SFO11:17 pmSan Francisco
$671
Find similar
Copa Airlines
Nov 12
SFO12:36 amSan Francisco
18h 10m
1 stop
VVI10:46 pmSanta Cruz de la Sierra Viru Viru Intl
Nov 24
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
15h 37m
1 stop
SFO11:17 pmSan Francisco
$756
Find similar
Copa Airlines
Apr 4
SFO1:42 amSan Francisco
18h 08m
1 stop
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 6
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
25h 25m
1 stop
SFO11:40 pmSan Francisco
$821
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momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 11/13

4:15 pm-10:46 pm

2 stops26h 31m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/24

11:40 am-7:24 am

2 stops23h 44m

$638

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 11/29

12:36 am-3:36 am

1 stop23h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/6

11:40 am-11:17 pm

1 stop15h 37m

$671

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Fri 11/28

12:43 am-10:46 pm

2 stops18h 03m

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/6

11:40 am-9:05 pm

2 stops37h 25m

$675

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 2/7

1:35 am-2:35 am

2 stops21h 00m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/13

3:40 am-11:20 pm

2 stops23h 40m

$696

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 2/8

11:10 pm-2:35 am

2 stops47h 25m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/13

3:40 am-11:20 pm

2 stops23h 40m

$701

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 4/4

12:45 am-10:50 pm

2 stops19h 05m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:44 am-10:19 am

2 stops25h 35m

$712

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 11/30

7:10 pm-3:36 am

2 stops28h 26m

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/6

11:40 am-7:26 pm

2 stops35h 46m

$770

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 12/1

8:25 am-4:35 am

2 stops40h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sun 12/7

10:43 am-11:29 am

2 stops28h 46m

$815

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 4/4

1:42 am-10:50 pm

1 stop18h 08m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

1:15 am-11:40 pm

1 stop25h 25m

$821

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 11/30

10:39 am-4:35 am

2 stops37h 56m

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/6

11:15 am-9:44 am

2 stops26h 29m

$980

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from San Francisco to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from San Francisco is in March. Flight prices, which tend to average around $631, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in March, then you should wait until September to fly from San Francisco, when ticket prices are also cheap, with an average price of $644.

What is the cheapest day to depart on your flight to Santa Cruz de la Sierra?

The cheapest day to depart on your flight to Santa Cruz de la Sierra is on a Friday when prices can be found for as low as $741. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santa Cruz de la Sierra on Sunday is $985.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

In the afternoon is the cheapest time of day to fly from San Francisco to Santa Cruz de la Sierra when you can find flight prices for as low as $670. Flying to Santa Cruz de la Sierra in the afternoon is an ideal time because this is during off-peak travel hours. Flights in the evening are often more expensive with an average ticket price of $903.

Can stopping save me money on San Francisco to Santa Cruz de la Sierra flights?

You could potentially save up to 17% on your flight if you consider stops on a San Francisco to Santa Cruz de la Sierra flight.

When to book flights from San Francisco to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santa Cruz de la Sierra (SFO to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santa Cruz de la Sierra

Direct flights

None
There are no direct flights from San Francisco to Santa Cruz de la Sierra. There are no popular flight routes from San Francisco to Santa Cruz de la Sierra.
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  • How far is San Francisco to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The distance between San Francisco and Santa Cruz de la Sierra Viru Viru Intl is about 5428.9 mi. Flights usually cover this in 14h 51m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Santa Cruz de la Sierra?

Best airlines flying from San Francisco to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from San Francisco to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $585Free CancellationRating
6.6
2,467 reviews
Search Avianca flights
Copa AirlinesPriceFrom $622Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $637Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santa Cruz de la Sierra?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Francisco to Santa Cruz de la Sierra. momondo saves you time and could save you money on your trip.

Can I find flights from San Francisco to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. All flights to Santa Cruz de la Sierra from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from San Francisco and alert you when they change.

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