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Cheap flights from San Francisco to Santa Cruz de la Sierra from $299

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santa Cruz de la Sierra departing on 12/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
11:10 pm - 2:35 am
SFO
-
VVI
23h 25m2 stops
Avianca Logo
3:40 am - 10:50 pm
VVI
-
SFO
22h 10m2 stops
$618Avianca
Mon, Mar 2 - Tue, Mar 10
United Airlines Logo
12:55 pm - 10:50 pm
SFO
-
VVI
29h 55m2 stops
United Airlines Logo
11:44 am - 11:12 pm
VVI
-
SFO
39h 28m2 stops
$638United Airlines
Fri, Jan 30 - Tue, Feb 3
Avianca Logo
12:05 am - 1:50 am
SFO
-
VVI
22h 45m2 stops
Avianca Logo
2:55 am - 12:35 pm
VVI
-
SFO
36h 40m2 stops
$859Avianca
Sun, Apr 12 - Mon, Apr 27
United Airlines Logo
9:20 pm - 10:50 pm
SFO
-
VVI
21h 30m2 stops
United Airlines Logo
11:44 am - 11:20 pm
VVI
-
SFO
15h 36m1 stop
$908United Airlines
Fri, Jan 30 - Tue, Feb 3
United Airlines Logo
9:20 pm - 10:50 pm
SFO
-
VVI
21h 30m2 stops
United Airlines Logo
11:42 am - 11:16 pm
VVI
-
SFO
15h 34m1 stop
$1,013United Airlines
Sat, Jan 24 - Sat, Mar 7
United Airlines Logo
11:59 pm - 3:44 am
SFO
-
VVI
23h 45m2 stops
United Airlines Logo
11:44 am - 10:17 am
VVI
-
SFO
26h 33m2 stops
$1,045United Airlines
Tue, Feb 17 - Sat, Feb 28
United Airlines Logo
12:42 am - 3:44 am
SFO
-
VVI
23h 02m1 stop
United Airlines Logo
11:44 am - 11:20 pm
VVI
-
SFO
15h 36m1 stop
$1,288United Airlines
Thu, Jan 29 - Tue, Feb 3
United Airlines Logo
12:42 am - 10:50 pm
SFO
-
VVI
18h 08m1 stop
United Airlines Logo
11:42 am - 11:16 pm
VVI
-
SFO
15h 34m1 stop
$1,293United Airlines
Fri, Jan 23 - Sat, Mar 7
United Airlines Logo
8:00 pm - 10:46 pm
SFO
-
VVI
22h 46m2 stops
United Airlines Logo
11:44 am - 12:21 am
VVI
-
SFO
16h 37m2 stops
$1,295United Airlines
Mon, Dec 29 - Thu, Jan 1
Avianca Logo
1:35 am - 2:35 am
SFO
-
VVI
21h 00m2 stops
Avianca Logo
3:40 am - 12:00 pm
VVI
-
SFO
36h 20m2 stops
$1,412Avianca
Tue, Dec 30 - Mon, Jan 5

Avianca flights from San Francisco to Santa Cruz de la Sierra

Our best Avianca deals on San Francisco to Santa Cruz de la Sierra flight tickets
Avianca
Mar 2
SFO11:10 pmSan Francisco
23h 25m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Mar 10
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
22h 10m
2 stops
SFO10:50 pmSan Francisco
$618
Find similar
Avianca
Apr 12
SFO12:05 amSan Francisco
22h 45m
2 stops
VVI1:50 amSanta Cruz de la Sierra Viru Viru Intl
Apr 27
VVI2:55 amSanta Cruz de la Sierra Viru Viru Intl
36h 40m
2 stops
SFO12:35 pmSan Francisco
$859
Find similar
Avianca
Dec 30
SFO1:35 amSan Francisco
21h 00m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Jan 5
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
36h 20m
2 stops
SFO12:00 pmSan Francisco
$1,412
Find similar

United Airlines flights from San Francisco to Santa Cruz de la Sierra

Our best United Airlines deals on San Francisco to Santa Cruz de la Sierra flight tickets
United Airlines
Jan 30
SFO12:55 pmSan Francisco
29h 55m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Feb 3
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
39h 28m
2 stops
SFO11:12 pmSan Francisco
$638
Find similar
United Airlines
Jan 30
SFO9:20 pmSan Francisco
21h 30m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Feb 3
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
15h 36m
1 stop
SFO11:20 pmSan Francisco
$908
Find similar
United Airlines
Jan 24
SFO9:20 pmSan Francisco
21h 30m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Mar 7
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
15h 34m
1 stop
SFO11:16 pmSan Francisco
$1,013
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 3/2

11:10 pm-2:35 am

2 stops23h 25m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

3:40 am-10:50 pm

2 stops22h 10m

$618

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Fri 1/30

12:55 pm-10:50 pm

2 stops29h 55m

Santa Cruz de la Sierra Viru Viru Intl

Tue 2/3

11:44 am-11:12 pm

2 stops39h 28m

$638

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 4/12

12:05 am-1:50 am

2 stops22h 45m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/27

2:55 am-12:35 pm

2 stops36h 40m

$859

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Fri 1/30

9:20 pm-10:50 pm

2 stops21h 30m

Santa Cruz de la Sierra Viru Viru Intl

Tue 2/3

11:44 am-11:20 pm

1 stop15h 36m

$908

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 1/24

9:20 pm-10:50 pm

2 stops21h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/7

11:42 am-11:16 pm

1 stop15h 34m

$1,013

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 2/17

11:59 pm-3:44 am

2 stops23h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/28

11:44 am-10:17 am

2 stops26h 33m

$1,045

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 1/29

12:42 am-3:44 am

1 stop23h 02m

Santa Cruz de la Sierra Viru Viru Intl

Tue 2/3

11:44 am-11:20 pm

1 stop15h 36m

$1,288

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Fri 1/23

12:42 am-10:50 pm

1 stop18h 08m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/7

11:42 am-11:16 pm

1 stop15h 34m

$1,293

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 12/29

8:00 pm-10:46 pm

2 stops22h 46m

Santa Cruz de la Sierra Viru Viru Intl

Thu 1/1

11:44 am-12:21 am

2 stops16h 37m

$1,295

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 12/30

1:35 am-2:35 am

2 stops21h 00m

Santa Cruz de la Sierra Viru Viru Intl

Mon 1/5

3:40 am-12:00 pm

2 stops36h 20m

$1,412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from San Francisco to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santa Cruz de la Sierra?

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from San Francisco is in September. Flight prices, which tend to average around $644, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in September, then you should wait until November to fly from San Francisco, when ticket prices are also cheap, with an average price of $670.

What is the cheapest day to depart on your flight to Santa Cruz de la Sierra?

The cheapest day to depart on your flight to Santa Cruz de la Sierra is on a Friday when prices can be found for as low as $741. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santa Cruz de la Sierra on Sunday is $985.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

In the afternoon is the cheapest time of day to fly from San Francisco to Santa Cruz de la Sierra when you can find flight prices for as low as $670. Flying to Santa Cruz de la Sierra in the afternoon is an ideal time because this is during off-peak travel hours. Flights in the evening are often more expensive with an average ticket price of $903.

Can stopping save me money on San Francisco to Santa Cruz de la Sierra flights?

You could potentially save up to 17% on your flight if you consider stops on a San Francisco to Santa Cruz de la Sierra flight.

When to book flights from San Francisco to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santa Cruz de la Sierra (SFO to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santa Cruz de la Sierra

Fastest flight time

14h 51m

Direct flights

None
The fastest flight from San Francisco to Santa Cruz de la Sierra takes 14h 51m
There are no direct flights from San Francisco to Santa Cruz de la Sierra. There are no popular flight routes from San Francisco to Santa Cruz de la Sierra.
Search flight deals

  • How far is San Francisco to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The distance between San Francisco and Santa Cruz de la Sierra Viru Viru Intl is about 5428.9 mi. Flights usually cover this in 14h 51m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Santa Cruz de la Sierra?

Best airlines flying from San Francisco to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from San Francisco to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $622Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $637Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
AviancaPriceFrom $640Free CancellationRating
6.6
2,490 reviews
Search Avianca flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santa Cruz de la Sierra?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Francisco to Santa Cruz de la Sierra. momondo saves you time and could save you money on your trip.

Can I find flights from San Francisco to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. All flights to Santa Cruz de la Sierra from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from San Francisco and alert you when they change.

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