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Cheap flights from San Francisco to Santa Cruz de la Sierra from $355

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santa Cruz de la Sierra departing on 8/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:00 am - 10:40 pm
SFO
-
VVI
36h 40m
2 stops
United Airlines Logo
11:47 am - 4:57 pm
VVI
-
SFO
56h 10m
2 stops
$742United Airlines
Mon, Aug 17 - Mon, Aug 24
United Airlines Logo
10:30 am - 10:40 pm
SFO
-
VVI
33h 10m
2 stops
United Airlines Logo
11:47 am - 5:42 pm
VVI
-
SFO
32h 55m
2 stops
$742United Airlines
Mon, Aug 17 - Mon, Aug 24
United Airlines Logo
1:56 pm - 10:44 pm
SFO
-
VVI
29h 48m
2 stops
United Airlines Logo
11:47 am - 9:30 am
VVI
-
SFO
48h 43m
2 stops
$751United Airlines
Thu, Sep 3 - Tue, Sep 8
United Airlines Logo
2:00 pm - 10:44 pm
SFO
-
VVI
29h 44m
2 stops
United Airlines Logo
11:47 am - 12:30 am
VVI
-
SFO
39h 43m
2 stops
$751United Airlines
Thu, Sep 3 - Tue, Sep 8
Copa Airlines Logo
8:21 pm - 3:38 am
SFO
-
VVI
28h 17m
1 stop
Copa Airlines Logo
1:12 am - 6:25 pm
VVI
-
SFO
20h 13m
1 stop
$774Copa Airlines
Thu, Oct 22 - Wed, Oct 28
Multiple Airlines Logo
12:45 am - 2:30 am
SFO
-
VVI
22h 45m
2 stops
Multiple Airlines Logo
1:12 am - 12:04 am
VVI
-
SFO
25h 52m
2 stops
$774Multiple Airlines
Tue, Oct 20 - Tue, Oct 27
Copa Airlines Logo
1:12 am - 10:44 pm
SFO
-
VVI
18h 32m
1 stop
Copa Airlines Logo
11:47 am - 11:40 pm
VVI
-
SFO
14h 53m
1 stop
$822Copa Airlines
Wed, Sep 2 - Tue, Sep 8
Copa Airlines Logo
1:12 am - 10:40 pm
SFO
-
VVI
18h 28m
1 stop
Copa Airlines Logo
11:47 am - 11:40 pm
VVI
-
SFO
14h 53m
1 stop
$960Copa Airlines
Sun, Aug 16 - Mon, Aug 24
Avianca Logo
2:30 am - 2:30 am
SFO
-
VVI
21h 00m
2 stops
Avianca Logo
3:40 am - 1:00 pm
VVI
-
SFO
36h 20m
2 stops
$991Avianca
Tue, Oct 20 - Tue, Oct 27
Avianca Logo
11:55 pm - 2:30 am
SFO
-
VVI
23h 35m
2 stops
Avianca Logo
3:35 am - 6:25 am
VVI
-
SFO
29h 50m
3 stops
$1,010Avianca
Mon, Aug 17 - Sun, Aug 23

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Avianca flights from San Francisco to Santa Cruz de la Sierra

Our best Avianca deals on San Francisco to Santa Cruz de la Sierra flight tickets
Avianca
Oct 20
SFO2:30 amSan Francisco
21h 00m
2 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Oct 27
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
36h 20m
2 stops
SFO1:00 pmSan Francisco
$991
Avianca
Aug 17
SFO7:45 amSan Francisco
39h 45m
3 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Aug 23
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
29h 50m
3 stops
SFO6:25 amSan Francisco
$1,010
Avianca
Aug 17
SFO7:45 amSan Francisco
39h 45m
3 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Aug 23
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
29h 50m
3 stops
SFO6:25 amSan Francisco
$1,027

Copa Airlines flights from San Francisco to Santa Cruz de la Sierra

Our best Copa Airlines deals on San Francisco to Santa Cruz de la Sierra flight tickets
Copa Airlines
Sep 2
SFO1:12 amSan Francisco
18h 32m
1 stop
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Sep 8
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
14h 53m
1 stop
SFO11:40 pmSan Francisco
$822
Copa Airlines
Aug 16
SFO1:12 amSan Francisco
18h 28m
1 stop
VVI10:40 pmSanta Cruz de la Sierra Viru Viru Intl
Aug 24
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
14h 53m
1 stop
SFO11:40 pmSan Francisco
$960
Copa Airlines
Sep 6
SFO1:12 amSan Francisco
23h 26m
1 stop
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
Dec 31
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
15h 35m
1 stop
SFO11:17 pmSan Francisco
$1,067

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 8/17

7:00 am-10:40 pm

2 stops36h 40m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/24

11:47 am-4:57 pm

2 stops56h 10m

$742

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 8/17

10:30 am-10:40 pm

2 stops33h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/24

11:47 am-5:42 pm

2 stops32h 55m

$742

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 9/3

1:56 pm-10:44 pm

2 stops29h 48m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/8

11:47 am-9:30 am

2 stops48h 43m

$751

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 9/3

2:00 pm-10:44 pm

2 stops29h 44m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/8

11:47 am-12:30 am

2 stops39h 43m

$751

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 10/22

8:21 pm-3:38 am

1 stop28h 17m

Santa Cruz de la Sierra Viru Viru Intl

Wed 10/28

1:12 am-6:25 pm

1 stop20h 13m

$774

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 10/20

12:45 am-2:30 am

2 stops22h 45m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

1:12 am-12:04 am

2 stops25h 52m

$774

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Wed 9/2

1:12 am-10:44 pm

1 stop18h 32m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/8

11:47 am-11:40 pm

1 stop14h 53m

$822
Quickest round-trip

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 8/16

1:12 am-10:40 pm

1 stop18h 28m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/24

11:47 am-11:40 pm

1 stop14h 53m

$960

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 10/20

2:30 am-2:30 am

2 stops21h 00m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

3:40 am-1:00 pm

2 stops36h 20m

$991

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 8/17

11:55 pm-2:30 am

2 stops23h 35m

Santa Cruz de la Sierra Viru Viru Intl

Sun 8/23

3:35 am-6:25 am

3 stops29h 50m

$1,010

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from San Francisco to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from San Francisco is in March. Flight prices, which tend to average around $356, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in March, then you should wait until September to fly from San Francisco, when ticket prices are also cheap, with an average price of $644.

Can stopping save me money on San Francisco to Santa Cruz de la Sierra flights?

You could potentially save up to 23% on your flight if you consider stops on a San Francisco to Santa Cruz de la Sierra flight.

When to book flights from San Francisco to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santa Cruz de la Sierra (SFO to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santa Cruz de la Sierra

Fastest flight time

23h 35m

Direct flights

None
The fastest flight from San Francisco to Santa Cruz de la Sierra takes 23h 35m
There are no direct flights from San Francisco to Santa Cruz de la Sierra. There are no popular flight routes from San Francisco to Santa Cruz de la Sierra.
Search flight deals

Frequently asked questions about flying from San Francisco to Santa Cruz de la Sierra

  • How far is San Francisco to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The distance between San Francisco and Santa Cruz de la Sierra Viru Viru Intl is about 5428.0 mi. Flights usually cover this in 23h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Santa Cruz de la Sierra?

Best airlines flying from San Francisco to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from San Francisco to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $394Free CancellationRating
7.4
10,059 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $622Free CancellationRating
7.6
1,564 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santa Cruz de la Sierra?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Francisco to Santa Cruz de la Sierra. momondo saves you time and could save you money on your trip.

Can I find flights from San Francisco to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. All flights to Santa Cruz de la Sierra from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from San Francisco and alert you when they change.

An easier way to manage your Santa Cruz de la Sierra trip

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