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Cheap flights from San Francisco to Santa Cruz de la Sierra from $295

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santa Cruz de la Sierra departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santa Cruz de la Sierra

Cheap round-trip flights

Copa Airlines Logo
1:30 am - 10:25 pmSFO-VVI
17h 55m1 stop
Copa Airlines Logo
12:15 pm - 11:25 pmVVI-SFO
14h 10m1 stop
$623Copa Airlines
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Wed, Sep 10 - Mon, Sep 15
Logo
4:12 pm - 1:50 amSFO-VVI
30h 38m2 stops
Logo
1:09 am - 9:09 pmVVI-SFO
23h 00m1 stop
$626
Find Deal
Wed, Oct 22 - Tue, Oct 28
United Airlines Logo
6:58 pm - 10:25 pmSFO-VVI
24h 27m2 stops
United Airlines Logo
1:09 am - 9:10 pmVVI-SFO
23h 01m1 stop
$627United Airlines
Find Deal
Thu, Sep 11 - Sun, Sep 14
Logo
4:12 pm - 1:50 amSFO-VVI
30h 38m2 stops
Logo
3:05 am - 9:13 pmVVI-SFO
21h 08m2 stops
$635
Find Deal
Wed, Oct 22 - Tue, Oct 28
Logo
12:43 am - 10:17 pmSFO-VVI
42h 34m2 stops
Logo
3:05 am - 7:25 pmVVI-SFO
19h 20m2 stops
$636
Find Deal
Tue, Oct 21 - Tue, Oct 28
United Airlines Logo
12:43 am - 10:17 pmSFO-VVI
18h 34m2 stops
United Airlines Logo
1:09 am - 12:12 amVVI-SFO
26h 03m2 stops
$637United Airlines
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Sat, Oct 11 - Sat, Oct 25
United Airlines Logo
7:05 pm - 10:17 pmSFO-VVI
48h 12m2 stops
United Airlines Logo
1:09 am - 9:09 pmVVI-SFO
23h 00m1 stop
$644United Airlines
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Sun, Oct 12 - Sat, Oct 25
Avianca Logo
11:15 pm - 2:00 amSFO-VVI
22h 45m2 stops
Avianca Logo
3:05 am - 12:00 pmVVI-SFO
36h 55m2 stops
$975Avianca
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Fri, Nov 14 - Sat, Nov 29
LATAM Airlines Logo
6:00 am - 4:35 amSFO-VVI
19h 35m2 stops
LATAM Airlines Logo
10:43 am - 2:33 pmVVI-SFO
30h 50m2 stops
$1,064LATAM Airlines
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Sun, Oct 12 - Sun, Oct 26
LATAM Airlines Logo
6:00 am - 4:35 amSFO-VVI
43h 35m2 stops
LATAM Airlines Logo
7:26 am - 6:46 pmVVI-SFO
38h 20m2 stops
$1,097LATAM Airlines
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Wed, Oct 22 - Wed, Oct 29

United Airlines flights from San Francisco to Santa Cruz de la Sierra

Our best United Airlines deals on San Francisco to Santa Cruz de la Sierra flight tickets
United Airlines
Sep 11
SFO6:58 pmSan Francisco
24h 27m
2 stops
VVI10:25 pmSanta Cruz de la Sierra Viru Viru Intl
Sep 14
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
23h 01m
1 stop
SFO9:10 pmSan Francisco
$627
Find similar
United Airlines
Oct 11
SFO12:43 amSan Francisco
18h 34m
2 stops
VVI10:17 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 25
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
26h 03m
2 stops
SFO12:12 amSan Francisco
$637
Find similar
United Airlines
Oct 12
SFO7:05 pmSan Francisco
48h 12m
2 stops
VVI10:17 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 25
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
23h 00m
1 stop
SFO9:09 pmSan Francisco
$644
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LATAM Airlines flights from San Francisco to Santa Cruz de la Sierra

Our best LATAM Airlines deals on San Francisco to Santa Cruz de la Sierra flight tickets
LATAM Airlines
Oct 12
SFO6:00 amSan Francisco
19h 35m
2 stops
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Oct 26
VVI10:43 amSanta Cruz de la Sierra Viru Viru Intl
30h 50m
2 stops
SFO2:33 pmSan Francisco
$1,064
Find similar
LATAM Airlines
Oct 22
SFO6:00 amSan Francisco
43h 35m
2 stops
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Oct 29
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
38h 20m
2 stops
SFO6:46 pmSan Francisco
$1,097
Find similar
LATAM Airlines
Oct 12
SFO12:27 pmSan Francisco
37h 08m
2 stops
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Oct 26
VVI10:43 amSanta Cruz de la Sierra Viru Viru Intl
27h 49m
2 stops
SFO11:32 amSan Francisco
$1,123
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momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Wed 9/10

1:30 am-10:25 pm

1 stop17h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/15

12:15 pm-11:25 pm

1 stop14h 10m

$623

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Wed 10/22

4:12 pm-1:50 am

2 stops30h 38m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/28

1:09 am-9:09 pm

1 stop23h 00m

$626

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 9/11

6:58 pm-10:25 pm

2 stops24h 27m

Santa Cruz de la Sierra Viru Viru Intl

Sun 9/14

1:09 am-9:10 pm

1 stop23h 01m

$627

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Wed 10/22

4:12 pm-1:50 am

2 stops30h 38m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/28

3:05 am-9:13 pm

2 stops21h 08m

$635

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 10/21

12:43 am-10:17 pm

2 stops42h 34m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/28

3:05 am-7:25 pm

2 stops19h 20m

$636

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 10/11

12:43 am-10:17 pm

2 stops18h 34m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/25

1:09 am-12:12 am

2 stops26h 03m

$637

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 10/12

7:05 pm-10:17 pm

2 stops48h 12m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/25

1:09 am-9:09 pm

1 stop23h 00m

$644

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Fri 11/14

11:15 pm-2:00 am

2 stops22h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/29

3:05 am-12:00 pm

2 stops36h 55m

$975

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 10/12

6:00 am-4:35 am

2 stops19h 35m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/26

10:43 am-2:33 pm

2 stops30h 50m

$1,064

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Wed 10/22

6:00 am-4:35 am

2 stops43h 35m

Santa Cruz de la Sierra Viru Viru Intl

Wed 10/29

7:26 am-6:46 pm

2 stops38h 20m

$1,097

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from San Francisco to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from San Francisco is in March. Flight prices, which tend to average around $693, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in March, then you should wait until October to fly from San Francisco, when ticket prices are also cheap, with an average price of $712.

What is the cheapest day to depart on your flight to Santa Cruz de la Sierra?

The cheapest day to depart on your flight to Santa Cruz de la Sierra is on a Friday when prices can be found for as low as $741. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santa Cruz de la Sierra on Sunday is $985.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

In the afternoon is the cheapest time of day to fly from San Francisco to Santa Cruz de la Sierra when you can find flight prices for as low as $670. Flying to Santa Cruz de la Sierra in the afternoon is an ideal time because this is during off-peak travel hours. Flights in the evening are often more expensive with an average ticket price of $903.

Can stopping save me money on San Francisco to Santa Cruz de la Sierra flights?

You could potentially save up to 2% on your flight if you consider stops on a San Francisco to Santa Cruz de la Sierra flight.

When to book flights from San Francisco to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santa Cruz de la Sierra (SFO to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santa Cruz de la Sierra

Best Price Found

$295

Fastest flight time

13h 41m

Direct flights

None

Airports in Santa Cruz de la Sierra

1 airport
The best one-way flight to Santa Cruz de la Sierra from San Francisco in the past 72 hours is $295. The best round-trip flight deal from San Francisco to Santa Cruz de la Sierra found on momondo in the last 72 hours is $623.
The fastest flight from San Francisco to Santa Cruz de la Sierra takes 13h 41m
There are no direct flights from San Francisco to Santa Cruz de la Sierra. Popular non-direct route for this connection is San Francisco Airport - Santa Cruz de la Sierra Viru Viru Intl Airport.
There is 1 airport near Santa Cruz de la Sierra: Santa Cruz de la Sierra Viru Viru Intl (VVI)
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  • How far is San Francisco to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The distance between San Francisco and Santa Cruz de la Sierra Viru Viru Intl is about 5428.9 mi. Flights usually cover this in 13h 41m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Santa Cruz de la Sierra?

Best airlines flying from San Francisco to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from San Francisco to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $585Free CancellationRating
6.7
2,388 reviews
Search Avianca flights
United AirlinesPriceFrom $589Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $608Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santa Cruz de la Sierra?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Francisco to Santa Cruz de la Sierra. momondo saves you time and could save you money on your trip.

Can I find flights from San Francisco to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. All flights to Santa Cruz de la Sierra from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from San Francisco and alert you when they change.

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