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Cheap flights from San Francisco to Santa Cruz de la Sierra from $365

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santa Cruz de la Sierra departing on 5/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from San Francisco to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
1:23 am - 10:42 pm
SFO
-
VVI
18h 19m
1 stop
Copa Airlines Logo
1:15 am - 6:25 pm
VVI
-
SFO
20h 10m
1 stop
$754Copa Airlines
Tue, Apr 7 - Wed, Apr 22
United Airlines Logo
12:45 am - 3:40 am
SFO
-
VVI
23h 55m
2 stops
United Airlines Logo
11:48 am - 8:49 am
VVI
-
SFO
24h 01m
2 stops
$760United Airlines
Tue, Apr 7 - Thu, Apr 23
United Airlines Logo
11:59 pm - 10:42 pm
SFO
-
VVI
19h 43m
2 stops
United Airlines Logo
11:48 am - 10:38 am
VVI
-
SFO
25h 50m
2 stops
$769United Airlines
Tue, Apr 14 - Tue, Apr 21
Copa Airlines Logo
8:16 pm - 10:40 pm
SFO
-
VVI
23h 24m
1 stop
Copa Airlines Logo
1:12 am - 5:59 pm
VVI
-
SFO
19h 47m
1 stop
$774Copa Airlines
Thu, Jul 30 - Sat, Aug 29
Copa Airlines Logo
1:23 am - 10:42 pm
SFO
-
VVI
18h 19m
1 stop
Copa Airlines Logo
11:48 am - 6:25 pm
VVI
-
SFO
33h 37m
1 stop
$796Copa Airlines
Mon, Apr 13 - Tue, Apr 21
Avianca Logo
12:45 am - 2:30 am
SFO
-
VVI
22h 45m
2 stops
Avianca Logo
3:35 am - 6:58 pm
VVI
-
SFO
18h 23m
2 stops
$798Avianca
Tue, Apr 14 - Tue, Apr 21
Copa Airlines Logo
1:23 am - 10:42 pm
SFO
-
VVI
18h 19m
1 stop
Copa Airlines Logo
11:48 am - 6:25 pm
VVI
-
SFO
33h 37m
1 stop
$799Copa Airlines
Mon, Apr 13 - Tue, Apr 21
Copa Airlines Logo
8:16 pm - 10:40 pm
SFO
-
VVI
23h 24m
1 stop
Copa Airlines Logo
1:12 am - 11:40 pm
VVI
-
SFO
25h 28m
1 stop
$842Copa Airlines
Tue, Jul 21 - Sat, Aug 1
Copa Airlines Logo
1:12 am - 10:40 pm
SFO
-
VVI
18h 28m
1 stop
Copa Airlines Logo
1:12 am - 5:59 pm
VVI
-
SFO
19h 47m
1 stop
$882Copa Airlines
Wed, Jul 29 - Sat, Aug 29
Copa Airlines Logo
8:16 pm - 10:40 pm
SFO
-
VVI
23h 24m
1 stop
Copa Airlines Logo
1:12 am - 11:40 pm
VVI
-
SFO
25h 28m
1 stop
$890Copa Airlines
Tue, Jul 21 - Sat, Aug 1

Copa Airlines flights from San Francisco to Santa Cruz de la Sierra

Our best Copa Airlines deals on San Francisco to Santa Cruz de la Sierra flight tickets
Copa Airlines
Apr 7
SFO1:23 amSan Francisco
18h 19m
1 stop
VVI10:42 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 21
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
20h 10m
1 stop
SFO6:25 pmSan Francisco
$754
Copa Airlines
Jul 30
SFO8:16 pmSan Francisco
23h 24m
1 stop
VVI10:40 pmSanta Cruz de la Sierra Viru Viru Intl
Aug 29
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
19h 47m
1 stop
SFO5:59 pmSan Francisco
$774
Copa Airlines
Apr 13
SFO1:23 amSan Francisco
18h 19m
1 stop
VVI10:42 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 21
VVI11:48 amSanta Cruz de la Sierra Viru Viru Intl
33h 37m
1 stop
SFO6:25 pmSan Francisco
$796

Avianca flights from San Francisco to Santa Cruz de la Sierra

Our best Avianca deals on San Francisco to Santa Cruz de la Sierra flight tickets
Avianca
Apr 14
SFO12:45 amSan Francisco
22h 45m
2 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Apr 21
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 23m
2 stops
SFO6:58 pmSan Francisco
$798
Avianca
Aug 15
SFO7:45 amSan Francisco
39h 45m
3 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Aug 22
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
36h 15m
2 stops
SFO12:50 pmSan Francisco
$962
Avianca
Aug 15
SFO11:55 pmSan Francisco
23h 35m
2 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Aug 22
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
46h 00m
2 stops
SFO10:35 pmSan Francisco
$971

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 4/7

1:23 am-10:42 pm

1 stop18h 19m

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/22

1:15 am-6:25 pm

1 stop20h 10m

$754

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 4/7

12:45 am-3:40 am

2 stops23h 55m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/23

11:48 am-8:49 am

2 stops24h 01m

$760

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 4/14

11:59 pm-10:42 pm

2 stops19h 43m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/21

11:48 am-10:38 am

2 stops25h 50m

$769

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 7/30

8:16 pm-10:40 pm

1 stop23h 24m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/29

1:12 am-5:59 pm

1 stop19h 47m

$774

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 4/13

1:23 am-10:42 pm

1 stop18h 19m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/21

11:48 am-6:25 pm

1 stop33h 37m

$796

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 4/14

12:45 am-2:30 am

2 stops22h 45m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/21

3:35 am-6:58 pm

2 stops18h 23m

$798

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 4/13

1:23 am-10:42 pm

1 stop18h 19m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/21

11:48 am-6:25 pm

1 stop33h 37m

$799

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 7/21

8:16 pm-10:40 pm

1 stop23h 24m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/1

1:12 am-11:40 pm

1 stop25h 28m

$842
Quickest round-trip

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Wed 7/29

1:12 am-10:40 pm

1 stop18h 28m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/29

1:12 am-5:59 pm

1 stop19h 47m

$882

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Tue 7/21

8:16 pm-10:40 pm

1 stop23h 24m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/1

1:12 am-11:40 pm

1 stop25h 28m

$890

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from San Francisco to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from San Francisco is in March. Flight prices, which tend to average around $356, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in March, then you should wait until September to fly from San Francisco, when ticket prices are also cheap, with an average price of $644.

Can stopping save me money on San Francisco to Santa Cruz de la Sierra flights?

You could potentially save up to 26% on your flight if you consider stops on a San Francisco to Santa Cruz de la Sierra flight.

When to book flights from San Francisco to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santa Cruz de la Sierra (SFO to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santa Cruz de la Sierra

Fastest flight time

19h 35m

Direct flights

None
The fastest flight from San Francisco to Santa Cruz de la Sierra takes 19h 35m
There are no direct flights from San Francisco to Santa Cruz de la Sierra. There are no popular flight routes from San Francisco to Santa Cruz de la Sierra.
Search flight deals

  • How far is San Francisco to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The distance between San Francisco and Santa Cruz de la Sierra Viru Viru Intl is about 5428.9 mi. Flights usually cover this in 19h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Francisco Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Santa Cruz de la Sierra?

Best airlines flying from San Francisco to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from San Francisco to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $622Free CancellationRating
7.5
1,573 reviews
Search Copa Airlines flights
AviancaPriceFrom $633Free CancellationRating
6.5
2,503 reviews
Search Avianca flights
United AirlinesPriceFrom $637Free CancellationRating
7.4
9,454 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santa Cruz de la Sierra?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Francisco to Santa Cruz de la Sierra. momondo saves you time and could save you money on your trip.

Can I find flights from San Francisco to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. All flights to Santa Cruz de la Sierra from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santa Cruz de la Sierra?

momondo provides multiple filters to help you find the best flight to Santa Cruz de la Sierra from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from San Francisco and alert you when they change.

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