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Cheap flights from Chicago to Santa Cruz de la Sierra from $270

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santa Cruz de la Sierra departing on 9/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago to Santa Cruz de la Sierra

Cheap round-trip flights

Logo
7:45 pm - 1:50 amORD-VVI
29h 05m2 stops
Logo
2:50 am - 10:41 pmVVI-ORD
20h 51m2 stops
$579
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mar., sep. 9 - lun., sep. 15
United Airlines Logo
7:55 pm - 10:17 pmORD-VVI
25h 22m2 stops
United Airlines Logo
1:09 am - 10:37 pmVVI-ORD
22h 28m2 stops
$581United Airlines
Find Deal
lun., oct. 6 - vie., oct. 17
United Airlines Logo
5:50 pm - 10:17 pmORD-VVI
51h 27m2 stops
United Airlines Logo
1:09 am - 9:36 pmVVI-ORD
21h 27m2 stops
$590United Airlines
Find Deal
jue., oct. 2 - dom., oct. 5
Copa Airlines Logo
7:53 am - 3:36 amORD-VVI
18h 43m1 stop
Copa Airlines Logo
11:59 am - 12:21 amVVI-ORD
13h 22m1 stop
$613Copa Airlines
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lun., oct. 6 - sáb., oct. 18
United Airlines Logo
9:08 pm - 10:46 pmORD-VVI
23h 38m2 stops
United Airlines Logo
1:09 am - 2:27 amVVI-ORD
27h 18m2 stops
$640United Airlines
Find Deal
sáb., nov. 22 - sáb., nov. 29
United Airlines Logo
6:00 am - 10:19 pmORD-VVI
15h 19m2 stops
United Airlines Logo
1:09 am - 12:15 amVVI-ORD
24h 06m2 stops
$649United Airlines
Find Deal
dom., ago. 10 - mié., ago. 20
Logo
3:07 pm - 3:37 amORD-VVI
11h 30m1 stop
Logo
2:50 am - 1:15 pmVVI-ORD
11h 25m1 stop
$658
Find Deal
lun., ago. 18 - vie., ago. 29
Avianca Logo
10:54 am - 1:50 amORD-VVI
13h 56m2 stops
Avianca Logo
2:50 am - 1:15 pmVVI-ORD
11h 25m1 stop
$703Avianca
Find Deal
lun., oct. 6 - vie., oct. 17
Avianca Logo
8:50 am - 1:50 amORD-VVI
16h 00m2 stops
Avianca Logo
2:50 am - 1:15 pmVVI-ORD
11h 25m1 stop
$706Avianca
Find Deal
jue., oct. 2 - dom., oct. 5
Copa Airlines Logo
7:55 am - 10:19 pmORD-VVI
13h 24m1 stop
Copa Airlines Logo
12:15 pm - 12:21 amVVI-ORD
13h 06m1 stop
$826Copa Airlines
Find Deal
dom., ago. 10 - jue., ago. 21

United Airlines flights from Chicago to Santa Cruz de la Sierra

Our best United Airlines deals on Chicago to Santa Cruz de la Sierra flight tickets
United Airlines
Oct 6
ORD7:55 pmChicago O'Hare Intl
25h 22m
2 stops
VVI10:17 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 17
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
22h 28m
2 stops
ORD10:37 pmChicago O'Hare Intl
$581
Find similar
United Airlines
Oct 2
ORD5:50 pmChicago O'Hare Intl
51h 27m
2 stops
VVI10:17 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 5
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
21h 27m
2 stops
ORD9:36 pmChicago O'Hare Intl
$590
Find similar
United Airlines
Aug 9
ORD7:35 pmChicago O'Hare Intl
25h 44m
2 stops
VVI10:19 pmSanta Cruz de la Sierra Viru Viru Intl
Aug 20
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
24h 06m
2 stops
ORD12:15 amChicago O'Hare Intl
$604
Find similar

Avianca flights from Chicago to Santa Cruz de la Sierra

Our best Avianca deals on Chicago to Santa Cruz de la Sierra flight tickets
Avianca
Oct 6
ORD10:54 amChicago O'Hare Intl
13h 56m
2 stops
VVI1:50 amSanta Cruz de la Sierra Viru Viru Intl
Oct 17
VVI2:50 amSanta Cruz de la Sierra Viru Viru Intl
11h 25m
1 stop
ORD1:15 pmChicago O'Hare Intl
$703
Find similar
Avianca
Oct 2
ORD8:50 amChicago O'Hare Intl
16h 00m
2 stops
VVI1:50 amSanta Cruz de la Sierra Viru Viru Intl
Oct 5
VVI2:50 amSanta Cruz de la Sierra Viru Viru Intl
11h 25m
1 stop
ORD1:15 pmChicago O'Hare Intl
$706
Find similar
Avianca
Aug 29
ORD8:50 amChicago O'Hare Intl
16h 00m
2 stops
VVI1:50 amSanta Cruz de la Sierra Viru Viru Intl
Sep 6
VVI2:50 amSanta Cruz de la Sierra Viru Viru Intl
11h 25m
1 stop
ORD1:15 pmChicago O'Hare Intl
$727
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from Chicago to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

mar. 9/9

7:45 pm-1:50 am

2 stops29h 05m

Santa Cruz de la Sierra Viru Viru Intl

lun. 9/15

2:50 am-10:41 pm

2 stops20h 51m

$579

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

lun. 10/6

7:55 pm-10:17 pm

2 stops25h 22m

Santa Cruz de la Sierra Viru Viru Intl

vie. 10/17

1:09 am-10:37 pm

2 stops22h 28m

$581

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

jue. 10/2

5:50 pm-10:17 pm

2 stops51h 27m

Santa Cruz de la Sierra Viru Viru Intl

dom. 10/5

1:09 am-9:36 pm

2 stops21h 27m

$590

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

lun. 10/6

7:53 am-3:36 am

1 stop18h 43m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 10/18

11:59 am-12:21 am

1 stop13h 22m

$613

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

sáb. 11/22

9:08 pm-10:46 pm

2 stops23h 38m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 11/29

1:09 am-2:27 am

2 stops27h 18m

$640

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

dom. 8/10

6:00 am-10:19 pm

2 stops15h 19m

Santa Cruz de la Sierra Viru Viru Intl

mié. 8/20

1:09 am-12:15 am

2 stops24h 06m

$649

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

lun. 8/18

3:07 pm-3:37 am

1 stop11h 30m

Santa Cruz de la Sierra Viru Viru Intl

vie. 8/29

2:50 am-1:15 pm

1 stop11h 25m

$658

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

lun. 10/6

10:54 am-1:50 am

2 stops13h 56m

Santa Cruz de la Sierra Viru Viru Intl

vie. 10/17

2:50 am-1:15 pm

1 stop11h 25m

$703

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

jue. 10/2

8:50 am-1:50 am

2 stops16h 00m

Santa Cruz de la Sierra Viru Viru Intl

dom. 10/5

2:50 am-1:15 pm

1 stop11h 25m

$706

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

dom. 8/10

7:55 am-10:19 pm

1 stop13h 24m

Santa Cruz de la Sierra Viru Viru Intl

jue. 8/21

12:15 pm-12:21 am

1 stop13h 06m

$826

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Chicago to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Cruz de la Sierra?

The cheapest day to depart on your flight to Santa Cruz de la Sierra is on a Wednesday when prices can be found for as low as $742. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Santa Cruz de la Sierra on Friday is $940.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

In the morning is the cheapest time of day to fly from Chicago to Santa Cruz de la Sierra when you can find flight prices for as low as $798. Flying to Santa Cruz de la Sierra in the morning is an ideal time because this is during off-peak travel hours. Flights at noon are often more expensive with an average ticket price of $935.

Can stopping save me money on Chicago to Santa Cruz de la Sierra flights?

You could potentially save up to 2% on your flight if you consider stops on a Chicago to Santa Cruz de la Sierra flight.

When to book flights from Chicago to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santa Cruz de la Sierra (CHI to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santa Cruz de la Sierra

Best Price Found

$270

Fastest flight time

11h 30m

Direct flights

None

Airports in Santa Cruz de la Sierra

1 airport
The best one-way flight to Santa Cruz de la Sierra from Chicago in the past 72 hours is $270. The best round-trip flight deal from Chicago to Santa Cruz de la Sierra found on momondo in the last 72 hours is $579.
The fastest flight from Chicago to Santa Cruz de la Sierra takes 11h 30m
There are no direct flights from Chicago to Santa Cruz de la Sierra. Popular non-direct route for this connection is Chicago O'Hare Intl Airport - Santa Cruz de la Sierra Viru Viru Intl Airport.
There is 1 airport near Santa Cruz de la Sierra: Santa Cruz de la Sierra Viru Viru Intl (VVI)
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  • How far is Chicago to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The straight-line distance from Chicago to Santa Cruz de la Sierra Viru Viru Intl is 4407.1 mi. 11h 30m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The travel and health documents required for your trip to Santa Cruz de la Sierra Viru Viru Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Cruz de la Sierra Viru Viru Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Chicago to Santa Cruz de la Sierra?

Best airlines flying from Chicago to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Chicago to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $566Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $589Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santa Cruz de la Sierra?

It is quick and easy to find Chicago to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Chicago to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Cruz de la Sierra from Chicago with this policy.

How can momondo help me find flights from Chicago to Santa Cruz de la Sierra?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Cruz de la Sierra from Chicago.

I’m not ready to book a flight from Chicago to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Santa Cruz de la Sierra flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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