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Cheap flights from Chicago to Santa Cruz de la Sierra from $331

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Santa Cruz de la Sierra departing on 6/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Chicago to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:06 am - 10:42 pm
ORD
-
VVI
13h 36m
1 stop
Copa Airlines Logo
11:48 am - 1:13 am
VVI
-
ORD
14h 25m
1 stop
$562Copa Airlines
Tue, Apr 21 - Tue, Apr 28
Copa Airlines Logo
3:05 pm - 10:42 pm
ORD
-
VVI
30h 37m
1 stop
Copa Airlines Logo
1:12 am - 1:15 am
VVI
-
ORD
25h 03m
1 stop
$612Copa Airlines
Mon, Apr 13 - Wed, May 6
Copa Airlines Logo
3:05 pm - 10:42 pm
ORD
-
VVI
30h 37m
1 stop
Copa Airlines Logo
11:47 am - 1:15 am
VVI
-
ORD
14h 28m
1 stop
$624Copa Airlines
Thu, Apr 16 - Thu, May 7
Copa Airlines Logo
8:06 am - 3:40 am
ORD
-
VVI
18h 34m
1 stop
Copa Airlines Logo
1:12 am - 1:15 am
VVI
-
ORD
25h 03m
1 stop
$628Copa Airlines
Fri, Apr 17 - Sat, May 2
Copa Airlines Logo
3:05 pm - 3:40 am
ORD
-
VVI
11h 35m
1 stop
Copa Airlines Logo
1:12 am - 1:15 am
VVI
-
ORD
25h 03m
1 stop
$634Copa Airlines
Fri, Apr 17 - Tue, May 5
Copa Airlines Logo
8:06 am - 10:42 pm
ORD
-
VVI
13h 36m
1 stop
Copa Airlines Logo
11:47 am - 1:15 am
VVI
-
ORD
14h 28m
1 stop
$635Copa Airlines
Wed, Apr 15 - Mon, May 4
Copa Airlines Logo
3:05 pm - 10:42 pm
ORD
-
VVI
30h 37m
1 stop
Copa Airlines Logo
1:12 am - 1:15 am
VVI
-
ORD
25h 03m
1 stop
$638Copa Airlines
Thu, Apr 16 - Sat, May 2
Copa Airlines Logo
8:06 am - 3:40 am
ORD
-
VVI
18h 34m
1 stop
Copa Airlines Logo
11:47 am - 1:15 am
VVI
-
ORD
14h 28m
1 stop
$647Copa Airlines
Wed, Apr 15 - Sat, May 2
Avianca Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
Avianca Logo
3:35 am - 9:20 pm
VVI
-
ORD
18h 45m
1 stop
$670Avianca
Tue, May 5 - Tue, May 26
Avianca Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
Avianca Logo
3:35 am - 9:20 pm
VVI
-
ORD
18h 45m
1 stop
$679Avianca
Fri, May 29 - Fri, Jun 5

Avianca flights from Chicago to Santa Cruz de la Sierra

Our best Avianca deals on Chicago to Santa Cruz de la Sierra flight tickets
Avianca
May 8
ORD11:20 pmChicago O'Hare Intl
26h 10m
1 stop
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
May 10
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
$670
Avianca
May 29
ORD11:20 pmChicago O'Hare Intl
26h 10m
1 stop
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Jun 5
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
$679
Avianca
Apr 12
ORD11:20 pmChicago O'Hare Intl
26h 10m
1 stop
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Apr 15
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
$700

Copa Airlines flights from Chicago to Santa Cruz de la Sierra

Our best Copa Airlines deals on Chicago to Santa Cruz de la Sierra flight tickets
Copa Airlines
Apr 21
ORD8:06 amChicago O'Hare Intl
13h 36m
1 stop
VVI10:42 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 28
VVI11:48 amSanta Cruz de la Sierra Viru Viru Intl
14h 25m
1 stop
ORD1:13 amChicago O'Hare Intl
$562
Copa Airlines
Apr 13
ORD3:05 pmChicago O'Hare Intl
30h 37m
1 stop
VVI10:42 pmSanta Cruz de la Sierra Viru Viru Intl
May 6
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
25h 03m
1 stop
ORD1:15 amChicago O'Hare Intl
$612
Copa Airlines
Apr 16
ORD3:05 pmChicago O'Hare Intl
30h 37m
1 stop
VVI10:42 pmSanta Cruz de la Sierra Viru Viru Intl
May 5
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
13h 54m
1 stop
ORD2:06 pmChicago O'Hare Intl
$624

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Chicago to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 4/21

8:06 am-10:42 pm

1 stop13h 36m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/28

11:48 am-1:13 am

1 stop14h 25m

$562

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 4/13

3:05 pm-10:42 pm

1 stop30h 37m

Santa Cruz de la Sierra Viru Viru Intl

Wed 5/6

1:12 am-1:15 am

1 stop25h 03m

$612

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 4/16

3:05 pm-10:42 pm

1 stop30h 37m

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/7

11:47 am-1:15 am

1 stop14h 28m

$624

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 4/17

8:06 am-3:40 am

1 stop18h 34m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

1:12 am-1:15 am

1 stop25h 03m

$628

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 4/17

3:05 pm-3:40 am

1 stop11h 35m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

1:12 am-1:15 am

1 stop25h 03m

$634

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 4/15

8:06 am-10:42 pm

1 stop13h 36m

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/4

11:47 am-1:15 am

1 stop14h 28m

$635

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 4/16

3:05 pm-10:42 pm

1 stop30h 37m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

1:12 am-1:15 am

1 stop25h 03m

$638

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 4/15

8:06 am-3:40 am

1 stop18h 34m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

11:47 am-1:15 am

1 stop14h 28m

$647

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 5/5

11:20 pm-2:30 am

1 stop26h 10m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/26

3:35 am-9:20 pm

1 stop18h 45m

$670

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 5/29

11:20 pm-2:30 am

1 stop26h 10m

Santa Cruz de la Sierra Viru Viru Intl

Fri 6/5

3:35 am-9:20 pm

1 stop18h 45m

$679

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Chicago to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Santa Cruz de la Sierra?

Can stopping save me money on Chicago to Santa Cruz de la Sierra flights?

You could potentially save up to 2% on your flight if you consider stops on a Chicago to Santa Cruz de la Sierra flight.

When to book flights from Chicago to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Santa Cruz de la Sierra (CHI to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Santa Cruz de la Sierra

Fastest flight time

13h 16m

Direct flights

None
The fastest flight from Chicago to Santa Cruz de la Sierra takes 13h 16m
There are no direct flights from Chicago to Santa Cruz de la Sierra. There are no popular flight routes from Chicago to Santa Cruz de la Sierra.
Search flight deals

  • How far is Chicago to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The straight-line distance from Chicago to Santa Cruz de la Sierra Viru Viru Intl is 4407.1 mi. 13h 16m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The travel and health documents required for your trip to Santa Cruz de la Sierra Viru Viru Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Cruz de la Sierra Viru Viru Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Chicago to Santa Cruz de la Sierra?

Best airlines flying from Chicago to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Chicago to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $278Free CancellationRating
7.4
9,429 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $458Free CancellationRating
7.5
1,568 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santa Cruz de la Sierra?

It is quick and easy to find Chicago to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Chicago to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Cruz de la Sierra from Chicago with this policy.

How can momondo help me find flights from Chicago to Santa Cruz de la Sierra?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Cruz de la Sierra from Chicago.

I’m not ready to book a flight from Chicago to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Santa Cruz de la Sierra flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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