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Cheap flights from Santa Ana, California to Des Moines from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Des Moines departing on 1/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana, California to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
9:36 am - 2:54 pmSNA-DSM
3h 18mnonstop
Allegiant Air Logo
7:00 am - 8:46 amDSM-SNA
3h 46mnonstop
$120Allegiant Air
Find Deal
Thu, Dec 4 - Sun, Dec 7
Allegiant Air Logo
9:37 am - 3:03 pmSNA-DSM
3h 26mnonstop
Allegiant Air Logo
7:00 am - 8:47 amDSM-SNA
3h 47mnonstop
$152Allegiant Air
Find Deal
Thu, Jan 15 - Sun, Jan 18
Allegiant Air Logo
9:37 am - 3:03 pmSNA-DSM
3h 26mnonstop
Allegiant Air Logo
7:00 am - 8:47 amDSM-SNA
3h 47mnonstop
$157Allegiant Air
Find Deal
Thu, Jan 15 - Sun, Jan 18
Multiple Airlines Logo
7:45 am - 3:40 pmSNA-DSM
5h 55m1 stop
Multiple Airlines Logo
7:00 am - 8:47 amDSM-SNA
3h 47mnonstop
$164Multiple Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
Multiple Airlines Logo
1:20 pm - 3:40 pmSNA-DSM
24h 20m1 stop
Multiple Airlines Logo
7:00 am - 8:47 amDSM-SNA
3h 47mnonstop
$166Multiple Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
Multiple Airlines Logo
11:39 am - 6:38 pmSNA-DSM
28h 59m1 stop
Multiple Airlines Logo
7:00 am - 8:46 amDSM-SNA
3h 46mnonstop
$188Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Multiple Airlines Logo
1:20 pm - 3:40 pmSNA-DSM
24h 20m1 stop
Multiple Airlines Logo
8:30 am - 4:36 pmDSM-SNA
10h 06m1 stop
$189Multiple Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
Multiple Airlines Logo
7:45 am - 10:09 pmSNA-DSM
12h 24m2 stops
Multiple Airlines Logo
8:30 am - 4:36 pmDSM-SNA
10h 06m1 stop
$225Multiple Airlines
Find Deal
Thu, Jan 15 - Sun, Jan 18
Multiple Airlines Logo
9:36 am - 2:54 pmSNA-DSM
3h 18mnonstop
Multiple Airlines Logo
4:21 pm - 10:23 pmDSM-SNA
32h 02m2 stops
$251Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Multiple Airlines Logo
9:36 am - 2:54 pmSNA-DSM
3h 18mnonstop
Multiple Airlines Logo
4:21 pm - 10:23 pmDSM-SNA
32h 02m3 stops
$263Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7

Allegiant Air flights from Santa Ana, California to Des Moines

Our best Allegiant Air deals on Santa Ana, California to Des Moines flight tickets
Allegiant Air
Dec 4
SNA9:36 amSanta Ana J. Wayne/Orange Cnty
3h 18m
DSM2:54 pmDes Moines
Dec 7
DSM7:00 amDes Moines
3h 46m
SNA8:46 amSanta Ana J. Wayne/Orange Cnty
$120
Find similar
Allegiant Air
Jan 15
SNA9:37 amSanta Ana J. Wayne/Orange Cnty
3h 26m
DSM3:03 pmDes Moines
Jan 18
DSM7:00 amDes Moines
3h 47m
SNA8:47 amSanta Ana J. Wayne/Orange Cnty
$152
Find similar
Allegiant Air
Jan 15
SNA9:37 amSanta Ana J. Wayne/Orange Cnty
3h 26m
DSM3:03 pmDes Moines
Jan 18
DSM7:00 amDes Moines
3h 47m
SNA8:47 amSanta Ana J. Wayne/Orange Cnty
$157
Find similar

American Airlines flights from Santa Ana, California to Des Moines

Our best American Airlines deals on Santa Ana, California to Des Moines flight tickets
American Airlines
Feb 12
SNA9:47 amSanta Ana J. Wayne/Orange Cnty
5h 49m
1 stop
DSM5:36 pmDes Moines
Feb 15
DSM6:20 pmDes Moines
5h 34m
1 stop
SNA9:54 pmSanta Ana J. Wayne/Orange Cnty
$291
Find similar
American Airlines
Dec 22
SNA3:04 pmSanta Ana J. Wayne/Orange Cnty
6h 26m
1 stop
DSM11:30 pmDes Moines
Jan 1
DSM2:40 pmDes Moines
5h 59m
1 stop
SNA6:39 pmSanta Ana J. Wayne/Orange Cnty
$405
Find similar
American Airlines
Dec 12
SNA12:28 pmSanta Ana J. Wayne/Orange Cnty
8h 31m
2 stops
DSM10:59 pmDes Moines
Dec 15
DSM8:50 amDes Moines
7h 21m
1 stop
SNA2:11 pmSanta Ana J. Wayne/Orange Cnty
$507
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 12/4

9:36 am-2:54 pm

Nonstop3h 18m

Des Moines

Sun 12/7

7:00 am-8:46 am

Nonstop3h 46m

$120

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

9:37 am-3:03 pm

Nonstop3h 26m

Des Moines

Sun 1/18

7:00 am-8:47 am

Nonstop3h 47m

$152

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

9:37 am-3:03 pm

Nonstop3h 26m

Des Moines

Sun 1/18

7:00 am-8:47 am

Nonstop3h 47m

$157

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

7:45 am-3:40 pm

1 stop5h 55m

Des Moines

Sun 1/18

7:00 am-8:47 am

Nonstop3h 47m

$164

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

1:20 pm-3:40 pm

1 stop24h 20m

Des Moines

Sun 1/18

7:00 am-8:47 am

Nonstop3h 47m

$166

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 12/4

11:39 am-6:38 pm

1 stop28h 59m

Des Moines

Sun 12/7

7:00 am-8:46 am

Nonstop3h 46m

$188

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

1:20 pm-3:40 pm

1 stop24h 20m

Des Moines

Sun 1/18

8:30 am-4:36 pm

1 stop10h 06m

$189

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

7:45 am-10:09 pm

2 stops12h 24m

Des Moines

Sun 1/18

8:30 am-4:36 pm

1 stop10h 06m

$225

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 12/4

9:36 am-2:54 pm

Nonstop3h 18m

Des Moines

Sun 12/7

4:21 pm-10:23 pm

2 stops32h 02m

$251

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 12/4

9:36 am-2:54 pm

Nonstop3h 18m

Des Moines

Sun 12/7

4:21 pm-10:23 pm

3 stops32h 02m

$263

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Santa Ana, California to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then September is your next best option. Flight prices from Santa Ana, California to Des Moines during September average around $198.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Santa Ana, California to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $275. Flights from Santa Ana, California to Des Moines on a Monday will generally be more expensive and average around $426. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Santa Ana, California to Des Moines in the morning for as low as $373. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $484. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Santa Ana J. Wayne/Orange Cnty to Des Moines flight route?

Fly from Santa Ana J. Wayne/Orange Cnty to Des Moines for the best Santa Ana J. Wayne/Orange Cnty - Des Moines flight prices

What cabin class options are available on Santa Ana J. Wayne/Orange Cnty to Des Moines flights?

There is only 1 cabin class available to choose from on Santa Ana J. Wayne/Orange Cnty to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santa Ana, California to Des Moines flight prices changed over time?

As of November 2025, prices for Santa Ana, California to Des Moines flights are approximately 16% more expensive when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Des Moines (SNA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Des Moines

Best Price Found

$192

Fastest flight time

3h 17m

Direct flights

Mon, Wed, Fri and Sun

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Santa Ana, California in the past 72 hours is $192. The best round-trip flight deal from Santa Ana, California to Des Moines found on momondo in the last 72 hours is $134.
The fastest flight from Santa Ana, California to Des Moines takes 3h 17m
Direct flights go from Santa Ana, California to Des Moines on Monday, Wednesday, Friday and Sunday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Des Moines: Des Moines (DSM)
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Des Moines by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Des Moines will travel around 1425.0 mi. By plane, this route typically takes 3h 18m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santa Ana, California to Des Moines?

  • What is the most popular airline from Santa Ana, California to Des Moines?

Best airlines flying from Santa Ana, California to Des Moines

Compare and see reviews for airlines that fly from Santa Ana, California to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $114Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
American AirlinesPriceFrom $276Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights
SouthwestPriceFrom $352Free CancellationRating
8.0
4,252 reviews
Search Southwest flights
United AirlinesPriceFrom $446Free CancellationRating
7.4
9,044 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Newton
Pella
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Santa Ana with this policy.

How can momondo help me find flights from Santa Ana to Des Moines?

Once all potential Santa Ana to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Ana to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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