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Cheap flights from Santa Ana, California to Des Moines from $99

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Des Moines departing on 6/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
4:46 pm - 10:01 pm
SNA
-
DSM
3h 15mnonstop
Allegiant Air Logo
1:38 pm - 3:16 pm
DSM
-
SNA
3h 38mnonstop
$180Allegiant Air
Thu, Oct 15 - Sun, Oct 18
Allegiant Air Logo
12:27 pm - 5:44 pm
SNA
-
DSM
3h 17mnonstop
Allegiant Air Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
$181Allegiant Air
Thu, Sep 3 - Sun, Sep 13
Allegiant Air Logo
9:32 am - 2:51 pm
SNA
-
DSM
3h 19mnonstop
Allegiant Air Logo
7:00 am - 8:42 am
DSM
-
SNA
3h 42mnonstop
$197Allegiant Air
Sun, Aug 9 - Sun, Aug 16
Allegiant Air Logo
4:46 pm - 10:01 pm
SNA
-
DSM
3h 15mnonstop
Allegiant Air Logo
2:18 pm - 3:56 pm
DSM
-
SNA
3h 38mnonstop
$206Allegiant Air
Thu, Oct 22 - Sun, Oct 25
Allegiant Air Logo
9:32 am - 2:51 pm
SNA
-
DSM
3h 19mnonstop
Allegiant Air Logo
7:00 am - 8:42 am
DSM
-
SNA
3h 42mnonstop
$207Allegiant Air
Sun, Aug 9 - Sun, Aug 16
Allegiant Air Logo
9:28 am - 2:42 pm
SNA
-
DSM
3h 14mnonstop
Allegiant Air Logo
9:30 am - 11:08 am
DSM
-
SNA
3h 38mnonstop
$214Allegiant Air
Thu, Jun 25 - Sat, Jun 27
Allegiant Air Logo
4:46 pm - 10:01 pm
SNA
-
DSM
3h 15mnonstop
Allegiant Air Logo
2:18 pm - 3:56 pm
DSM
-
SNA
3h 38mnonstop
$215Allegiant Air
Thu, Oct 22 - Sun, Oct 25
Allegiant Air Logo
4:46 pm - 10:01 pm
SNA
-
DSM
3h 15mnonstop
Allegiant Air Logo
2:18 pm - 3:56 pm
DSM
-
SNA
3h 38mnonstop
$225Allegiant Air
Thu, Oct 22 - Sun, Oct 25
Multiple Airlines Logo
8:10 pm - 11:10 am
SNA
-
DSM
13h 00m
1 stop
Multiple Airlines Logo
10:00 am - 11:37 am
DSM
-
SNA
3h 37mnonstop
$240Multiple Airlines
Thu, Sep 3 - Sun, Sep 13
Allegiant Air Logo
9:32 am - 2:51 pm
SNA
-
DSM
3h 19mnonstop
Allegiant Air Logo
7:00 am - 8:42 am
DSM
-
SNA
3h 42mnonstop
$247Allegiant Air
Thu, Aug 13 - Sun, Aug 16

Allegiant Air flights from Santa Ana, California to Des Moines

Our best Allegiant Air deals on Santa Ana, California to Des Moines flight tickets
Allegiant Air
Oct 15
SNA4:46 pmSanta Ana J. Wayne/Orange Cnty
3h 15m
DSM10:01 pmDes Moines
Oct 18
DSM1:38 pmDes Moines
3h 38m
SNA3:16 pmSanta Ana J. Wayne/Orange Cnty
$180
Allegiant Air
Sep 3
SNA12:27 pmSanta Ana J. Wayne/Orange Cnty
3h 17m
DSM5:44 pmDes Moines
Sep 13
DSM10:00 amDes Moines
3h 37m
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
$181
Allegiant Air
Aug 9
SNA9:32 amSanta Ana J. Wayne/Orange Cnty
3h 19m
DSM2:51 pmDes Moines
Aug 16
DSM7:00 amDes Moines
3h 42m
SNA8:42 amSanta Ana J. Wayne/Orange Cnty
$197

American Airlines flights from Santa Ana, California to Des Moines

Our best American Airlines deals on Santa Ana, California to Des Moines flight tickets
American Airlines
Jun 24
SNA2:31 pmSanta Ana J. Wayne/Orange Cnty
7h 27m
1 stop
DSM11:58 pmDes Moines
Jul 1
DSM5:45 amDes Moines
5h 10m
1 stop
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
$276
American Airlines
Jun 24
SNA2:31 pmSanta Ana J. Wayne/Orange Cnty
7h 27m
1 stop
DSM11:58 pmDes Moines
Jul 1
DSM5:45 amDes Moines
5h 10m
1 stop
SNA8:55 amSanta Ana J. Wayne/Orange Cnty
$294
American Airlines
Aug 6
SNA3:21 pmSanta Ana J. Wayne/Orange Cnty
6h 59m
1 stop
DSM12:20 amDes Moines
Aug 10
DSM5:30 amDes Moines
5h 22m
1 stop
SNA8:52 amSanta Ana J. Wayne/Orange Cnty
$339

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 29, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 10/15

4:46 pm-10:01 pm

Nonstop3h 15m

Des Moines

Sun 10/18

1:38 pm-3:16 pm

Nonstop3h 38m

$180

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 9/3

12:27 pm-5:44 pm

Nonstop3h 17m

Des Moines

Sun 9/13

10:00 am-11:37 am

Nonstop3h 37m

$181

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sun 8/9

9:32 am-2:51 pm

Nonstop3h 19m

Des Moines

Sun 8/16

7:00 am-8:42 am

Nonstop3h 42m

$197

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 10/22

4:46 pm-10:01 pm

Nonstop3h 15m

Des Moines

Sun 10/25

2:18 pm-3:56 pm

Nonstop3h 38m

$206

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sun 8/9

9:32 am-2:51 pm

Nonstop3h 19m

Des Moines

Sun 8/16

7:00 am-8:42 am

Nonstop3h 42m

$207
Quickest round-trip

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 6/25

9:28 am-2:42 pm

Nonstop3h 14m

Des Moines

Sat 6/27

9:30 am-11:08 am

Nonstop3h 38m

$214

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 10/22

4:46 pm-10:01 pm

Nonstop3h 15m

Des Moines

Sun 10/25

2:18 pm-3:56 pm

Nonstop3h 38m

$215

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 10/22

4:46 pm-10:01 pm

Nonstop3h 15m

Des Moines

Sun 10/25

2:18 pm-3:56 pm

Nonstop3h 38m

$225

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 9/3

8:10 pm-11:10 am

1 stop13h 00m

Des Moines

Sun 9/13

10:00 am-11:37 am

Nonstop3h 37m

$240

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 8/13

9:32 am-2:51 pm

Nonstop3h 19m

Des Moines

Sun 8/16

7:00 am-8:42 am

Nonstop3h 42m

$247

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Santa Ana, California to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in January, then September is your next best option. Flight prices from Santa Ana, California to Des Moines during September average around $197.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Santa Ana, California to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $349. Flights from Santa Ana, California to Des Moines on a Sunday will generally be more expensive and average around $478. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest Santa Ana J. Wayne/Orange Cnty to Des Moines flight route?

Fly from Santa Ana J. Wayne/Orange Cnty to Des Moines for the best Santa Ana J. Wayne/Orange Cnty - Des Moines flight prices

What cabin class options are available on Santa Ana, California to Des Moines flights?

There is only 1 cabin class available to choose from on Santa Ana, California to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santa Ana, California to Des Moines flights?

You could potentially save up to 7% on your flight if you consider stops on a Santa Ana, California to Des Moines flight.

How have Santa Ana, California to Des Moines flight prices changed over time?

As of May 2026, prices for Santa Ana, California to Des Moines flights are approximately 37% cheaper when compared to flights at the same time last year.

When to book flights from Santa Ana, California to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Des Moines (SNA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Des Moines

Best Price Found

$128

Fastest flight time

3h 14m

Direct flights

Mon, Fri and Sun

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Santa Ana, California in the past 72 hours is $128. The best round-trip flight deal from Santa Ana, California to Des Moines found on momondo in the last 72 hours is $200.
The fastest flight from Santa Ana, California to Des Moines takes 3h 14m
Direct flights go from Santa Ana, California to Des Moines on Monday, Friday and Sunday. The only airline offering direct flights is Allegiant Air.
There is 1 airport in Des Moines. From Santa Ana, California there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Des Moines

  • How far is Santa Ana J. Wayne/Orange Cnty to Des Moines by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Des Moines will travel around 1425.0 mi. By plane, this route typically takes 3h 14m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santa Ana, California to Des Moines?

  • What is the most popular airline from Santa Ana, California to Des Moines?

Best airlines flying from Santa Ana, California to Des Moines

Compare and see reviews for airlines that fly from Santa Ana, California to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $127Free CancellationRating
7.3
709 reviews
Search Allegiant Air flights
American AirlinesPriceFrom $260Free CancellationRating
7.1
11,644 reviews
Search American Airlines flights
United AirlinesPriceFrom $387Free CancellationRating
7.4
9,765 reviews
Search United Airlines flights

  • Allegiant Air Flights From Santa Ana, California to Des Moines

    Allegiant Air is one of the most popular airlines flying from Santa Ana, California to Des Moines, operating 1 flight/week on average for this route. A good Allegiant Air flight deal for Santa Ana, California to Des Moines starts from $127 round-trip, up to an average price of $198. Our users have rated Allegiant Air at 7.3/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Urbandale
Johnston
Newton
Boone
Osceola
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Santa Ana with this policy.

How can momondo help me find flights from Santa Ana to Des Moines?

Once all potential Santa Ana to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Ana to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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