Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santa Ana, California to Columbia from $318

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Columbia departing on 5/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santa Ana, California to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:45 am - 4:49 pm
SNA
-
COU
8h 04m
1 stop
American Airlines Logo
6:00 am - 10:41 am
COU
-
SNA
6h 41m
1 stop
$318American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
2:30 pm - 10:25 pm
SNA
-
COU
5h 55m
1 stop
American Airlines Logo
6:55 am - 3:34 pm
COU
-
SNA
10h 39m
2 stops
$384American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
11:33 am - 9:29 pm
SNA
-
COU
7h 56m
1 stop
American Airlines Logo
6:20 am - 2:24 pm
COU
-
SNA
10h 04m
1 stop
$439American Airlines
Sat, May 30 - Wed, Jun 3
American Airlines Logo
6:45 am - 4:49 pm
SNA
-
COU
8h 04m
2 stops
American Airlines Logo
6:20 am - 2:24 pm
COU
-
SNA
10h 04m
1 stop
$445American Airlines
Sat, May 30 - Wed, Jun 3
American Airlines Logo
12:33 pm - 10:25 pm
SNA
-
COU
7h 52m
2 stops
American Airlines Logo
6:55 am - 3:34 pm
COU
-
SNA
10h 39m
2 stops
$450American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
6:45 am - 7:02 pm
SNA
-
COU
10h 17m
2 stops
American Airlines Logo
11:45 am - 3:37 pm
COU
-
SNA
5h 52m
1 stop
$465American Airlines
Sat, Jul 11 - Wed, Jul 15
American Airlines Logo
6:45 am - 7:02 pm
SNA
-
COU
10h 17m
2 stops
American Airlines Logo
11:45 am - 6:41 pm
COU
-
SNA
8h 56m
2 stops
$470American Airlines
Sat, Jul 11 - Wed, Jul 15
American Airlines Logo
6:45 am - 4:49 pm
SNA
-
COU
8h 04m
2 stops
American Airlines Logo
7:16 am - 3:34 pm
COU
-
SNA
10h 18m
2 stops
$503American Airlines
Sat, May 30 - Wed, Jun 3
United Airlines Logo
8:45 am - 10:03 pm
SNA
-
COU
11h 18m
2 stops
United Airlines Logo
10:53 am - 8:55 pm
COU
-
SNA
12h 02m
2 stops
$540United Airlines
Tue, May 19 - Sat, May 23
United Airlines Logo
11:00 am - 8:49 pm
SNA
-
COU
7h 49m
1 stop
United Airlines Logo
10:53 am - 8:55 pm
COU
-
SNA
12h 02m
2 stops
$580United Airlines
Tue, May 19 - Sat, May 23

American Airlines flights from Santa Ana, California to Columbia, Missouri

Our best American Airlines deals on Santa Ana, California to Columbia, Missouri flight tickets
American Airlines
May 23
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 04m
1 stop
COU4:49 pmColumbia Regional
May 27
COU6:00 amColumbia Regional
6h 41m
1 stop
SNA10:41 amSanta Ana J. Wayne/Orange Cnty
$318
American Airlines
May 23
SNA2:30 pmSanta Ana J. Wayne/Orange Cnty
5h 55m
1 stop
COU10:25 pmColumbia Regional
May 27
COU6:55 amColumbia Regional
10h 39m
2 stops
SNA3:34 pmSanta Ana J. Wayne/Orange Cnty
$384
American Airlines
May 30
SNA11:33 amSanta Ana J. Wayne/Orange Cnty
7h 56m
1 stop
COU9:29 pmColumbia Regional
Jun 3
COU6:20 amColumbia Regional
10h 04m
1 stop
SNA2:24 pmSanta Ana J. Wayne/Orange Cnty
$439

United Airlines flights from Santa Ana, California to Columbia, Missouri

Our best United Airlines deals on Santa Ana, California to Columbia, Missouri flight tickets
United Airlines
May 19
SNA8:45 amSanta Ana J. Wayne/Orange Cnty
11h 18m
2 stops
COU10:03 pmColumbia Regional
May 23
COU10:53 amColumbia Regional
12h 02m
2 stops
SNA8:55 pmSanta Ana J. Wayne/Orange Cnty
$540
United Airlines
May 19
SNA11:00 amSanta Ana J. Wayne/Orange Cnty
7h 49m
1 stop
COU8:49 pmColumbia Regional
May 23
COU10:53 amColumbia Regional
12h 02m
2 stops
SNA8:55 pmSanta Ana J. Wayne/Orange Cnty
$580
United Airlines
May 7
SNA11:00 amSanta Ana J. Wayne/Orange Cnty
7h 49m
1 stop
COU8:49 pmColumbia Regional
May 12
COU9:00 amColumbia Regional
8h 03m
1 stop
SNA3:03 pmSanta Ana J. Wayne/Orange Cnty
$609

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 5/23

6:45 am-4:49 pm

1 stop8h 04m

Columbia Regional

Wed 5/27

6:00 am-10:41 am

1 stop6h 41m

$318

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 5/23

2:30 pm-10:25 pm

1 stop5h 55m

Columbia Regional

Wed 5/27

6:55 am-3:34 pm

2 stops10h 39m

$384

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 5/30

11:33 am-9:29 pm

1 stop7h 56m

Columbia Regional

Wed 6/3

6:20 am-2:24 pm

1 stop10h 04m

$439

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 5/30

6:45 am-4:49 pm

2 stops8h 04m

Columbia Regional

Wed 6/3

6:20 am-2:24 pm

1 stop10h 04m

$445

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 5/23

12:33 pm-10:25 pm

2 stops7h 52m

Columbia Regional

Wed 5/27

6:55 am-3:34 pm

2 stops10h 39m

$450

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 7/11

6:45 am-7:02 pm

2 stops10h 17m

Columbia Regional

Wed 7/15

11:45 am-3:37 pm

1 stop5h 52m

$465

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 7/11

6:45 am-7:02 pm

2 stops10h 17m

Columbia Regional

Wed 7/15

11:45 am-6:41 pm

2 stops8h 56m

$470

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 5/30

6:45 am-4:49 pm

2 stops8h 04m

Columbia Regional

Wed 6/3

7:16 am-3:34 pm

2 stops10h 18m

$503

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 5/19

8:45 am-10:03 pm

2 stops11h 18m

Columbia Regional

Sat 5/23

10:53 am-8:55 pm

2 stops12h 02m

$540

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 5/19

11:00 am-8:49 pm

1 stop7h 49m

Columbia Regional

Sat 5/23

10:53 am-8:55 pm

2 stops12h 02m

$580

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

See travel insights to Columbia from

How to get the cheapest flight ticket from Santa Ana, California to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Columbia Regional?

American Airlines and United Airlines are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to Columbia Regional

When to book flights from Santa Ana, California to Columbia, Missouri

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Columbia, Missouri according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Columbia, Missouri (SNA to COU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Columbia, Missouri

Fastest flight time

5h 57m

Direct flights

None
The fastest flight from Santa Ana, California to Columbia, Missouri takes 5h 57m
There are no direct flights from Santa Ana, California to Columbia, Missouri. There are no popular flight routes from Santa Ana, California to Columbia, Missouri.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Columbia, Missouri

  • How far is Santa Ana J. Wayne/Orange Cnty to Columbia Regional by plane?

    There are 1459.4 mi between Santa Ana J. Wayne/Orange Cnty and Columbia Regional. 5h 57m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The required travel and health documents for your Columbia Regional Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Columbia Regional Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santa Ana, California to Columbia, Missouri?

Best airlines flying from Santa Ana, California to Columbia, Missouri

Compare and see reviews for airlines that fly from Santa Ana, California to Columbia, Missouri with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $392Free CancellationRating
7.1
11,672 reviews
Search American Airlines flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Columbia?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Columbia for you.

Can I find flights from Santa Ana to Columbia with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Columbia from Santa Ana with this policy.

How can momondo help me find flights from Santa Ana to Columbia?

momondo provides multiple filters to help you find the best flight to Columbia from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Columbia right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Columbia flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Columbia, Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 6/3
Wed 6/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States