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Cheap flights from Santa Ana to Columbia from $318

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Columbia departing on 4/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:42 pm - 10:53 pm
SNA
-
COU
6h 11m
1 stop
American Airlines Logo
6:00 am - 12:38 pm
COU
-
SNA
8h 38m
1 stop
$318American Airlines
ven, apr 10 - sab, apr 18
American Airlines Logo
2:42 pm - 10:53 pm
SNA
-
COU
6h 11m
1 stop
American Airlines Logo
10:16 am - 6:01 pm
COU
-
SNA
9h 45m
2 stops
$324American Airlines
ven, apr 10 - sab, apr 18
United Airlines Logo
11:10 am - 9:03 pm
SNA
-
COU
7h 53m
1 stop
United Airlines Logo
11:30 am - 6:46 pm
COU
-
SNA
9h 16m
1 stop
$378United Airlines
mar, apr 14 - sab, apr 18
United Airlines Logo
11:10 am - 9:03 pm
SNA
-
COU
7h 53m
1 stop
United Airlines Logo
11:30 am - 8:48 pm
COU
-
SNA
11h 18m
2 stops
$384United Airlines
mar, apr 14 - sab, apr 18
American Airlines Logo
12:27 pm - 10:53 pm
SNA
-
COU
8h 26m
2 stops
American Airlines Logo
12:06 pm - 6:01 pm
COU
-
SNA
7h 55m
2 stops
$389American Airlines
ven, apr 10 - sab, apr 18
United Airlines Logo
11:10 am - 9:03 pm
SNA
-
COU
7h 53m
1 stop
United Airlines Logo
5:00 am - 11:37 am
COU
-
SNA
8h 37m
1 stop
$398United Airlines
mar, apr 14 - sab, apr 18
American Airlines Logo
12:47 pm - 10:36 pm
SNA
-
COU
7h 49m
1 stop
American Airlines Logo
5:39 pm - 10:45 pm
COU
-
SNA
7h 06m
1 stop
$403American Airlines
mer, mar 25 - dom, mar 29
United Airlines Logo
11:10 am - 9:03 pm
SNA
-
COU
7h 53m
1 stop
United Airlines Logo
11:30 am - 8:48 pm
COU
-
SNA
11h 18m
2 stops
$404United Airlines
mar, apr 14 - sab, apr 18
American Airlines Logo
12:26 pm - 10:36 pm
SNA
-
COU
8h 10m
2 stops
American Airlines Logo
5:39 pm - 10:45 pm
COU
-
SNA
7h 06m
1 stop
$409American Airlines
mer, mar 25 - dom, mar 29
United Airlines Logo
7:44 pm - 10:55 am
SNA
-
COU
13h 11m
2 stops
United Airlines Logo
11:30 am - 8:48 pm
COU
-
SNA
11h 18m
2 stops
$414United Airlines
mar, apr 14 - sab, apr 18

United Airlines flights from Santa Ana to Columbia, Missouri

Our best United Airlines deals on Santa Ana to Columbia, Missouri flight tickets
United Airlines
Apr 14
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
7h 53m
1 stop
COU9:03 pmColumbia Regional
Apr 18
COU11:30 amColumbia Regional
9h 16m
1 stop
SNA6:46 pmSanta Ana J. Wayne/Orange Cnty
$378
United Airlines
Apr 14
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
7h 53m
1 stop
COU9:03 pmColumbia Regional
Apr 18
COU11:30 amColumbia Regional
11h 18m
2 stops
SNA8:48 pmSanta Ana J. Wayne/Orange Cnty
$384
United Airlines
Apr 14
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
7h 53m
1 stop
COU9:03 pmColumbia Regional
Apr 18
COU5:00 amColumbia Regional
8h 37m
1 stop
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
$398

American Airlines flights from Santa Ana to Columbia, Missouri

Our best American Airlines deals on Santa Ana to Columbia, Missouri flight tickets
American Airlines
Apr 10
SNA2:42 pmSanta Ana J. Wayne/Orange Cnty
6h 11m
1 stop
COU10:53 pmColumbia Regional
Apr 18
COU6:00 amColumbia Regional
8h 38m
1 stop
SNA12:38 pmSanta Ana J. Wayne/Orange Cnty
$318
American Airlines
Apr 10
SNA2:42 pmSanta Ana J. Wayne/Orange Cnty
6h 11m
1 stop
COU10:53 pmColumbia Regional
Apr 18
COU10:16 amColumbia Regional
9h 45m
2 stops
SNA6:01 pmSanta Ana J. Wayne/Orange Cnty
$324
American Airlines
Apr 10
SNA12:27 pmSanta Ana J. Wayne/Orange Cnty
8h 26m
2 stops
COU10:53 pmColumbia Regional
Apr 18
COU12:06 pmColumbia Regional
7h 55m
2 stops
SNA6:01 pmSanta Ana J. Wayne/Orange Cnty
$389

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated marzo 11, 2026.
Use the filters below to find and compare flights from Santa Ana to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

ven 4/10

2:42 pm-10:53 pm

1 stop6h 11m

Columbia Regional

sab 4/18

6:00 am-12:38 pm

1 stop8h 38m

$318

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

ven 4/10

2:42 pm-10:53 pm

1 stop6h 11m

Columbia Regional

sab 4/18

10:16 am-6:01 pm

2 stops9h 45m

$324

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mar 4/14

11:10 am-9:03 pm

1 stop7h 53m

Columbia Regional

sab 4/18

11:30 am-6:46 pm

1 stop9h 16m

$378

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mar 4/14

11:10 am-9:03 pm

1 stop7h 53m

Columbia Regional

sab 4/18

11:30 am-8:48 pm

2 stops11h 18m

$384

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

ven 4/10

12:27 pm-10:53 pm

2 stops8h 26m

Columbia Regional

sab 4/18

12:06 pm-6:01 pm

2 stops7h 55m

$389

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mar 4/14

11:10 am-9:03 pm

1 stop7h 53m

Columbia Regional

sab 4/18

5:00 am-11:37 am

1 stop8h 37m

$398

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mer 3/25

12:47 pm-10:36 pm

1 stop7h 49m

Columbia Regional

dom 3/29

5:39 pm-10:45 pm

1 stop7h 06m

$403

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mar 4/14

11:10 am-9:03 pm

1 stop7h 53m

Columbia Regional

sab 4/18

11:30 am-8:48 pm

2 stops11h 18m

$404

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mer 3/25

12:26 pm-10:36 pm

2 stops8h 10m

Columbia Regional

dom 3/29

5:39 pm-10:45 pm

1 stop7h 06m

$409

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

mar 4/14

7:44 pm-10:55 am

2 stops13h 11m

Columbia Regional

sab 4/18

11:30 am-8:48 pm

2 stops11h 18m

$414

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from Santa Ana to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Columbia Regional?

United Airlines is the most popular carrier operating from Santa Ana J. Wayne/Orange Cnty to Columbia Regional

When to book flights from Santa Ana to Columbia, Missouri

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Columbia, Missouri according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Columbia, Missouri (SNA to COU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Columbia, Missouri

Fastest flight time

5h 42m

Direct flights

None
The fastest flight from Santa Ana to Columbia, Missouri takes 5h 42m
There are no direct flights from Santa Ana to Columbia, Missouri. There are no popular flight routes from Santa Ana to Columbia, Missouri.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Columbia Regional by plane?

    There are 1459.4 mi between Santa Ana J. Wayne/Orange Cnty and Columbia Regional. 5h 42m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The required travel and health documents for your Columbia Regional Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Columbia Regional Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santa Ana to Columbia, Missouri?

Best airlines flying from Santa Ana to Columbia, Missouri

Compare and see reviews for airlines that fly from Santa Ana to Columbia, Missouri with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $392Free CancellationRating
7.1
11,419 reviews
Search American Airlines flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Columbia?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Columbia for you.

Can I find flights from Santa Ana to Columbia with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Columbia from Santa Ana with this policy.

How can momondo help me find flights from Santa Ana to Columbia?

momondo provides multiple filters to help you find the best flight to Columbia from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Columbia right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Columbia flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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ven 4/10
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