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Cheap flights from Santa Ana, California to Columbia from $328

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Columbia departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:34 pm - 10:28 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
6h 54m1 stop Dallas/Fort Worth
American Airlines Logo
5:44 am - 10:36 amCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
6h 52m1 stop Chicago O'Hare Intl
$328American Airlines
Fri, Sep 4 - Thu, Sep 10
American Airlines Logo
12:14 pm - 8:12 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
5h 58m1 stop Dallas/Fort Worth
American Airlines Logo
5:44 am - 10:36 amCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
6h 52m1 stop Chicago O'Hare Intl
$363American Airlines
Fri, Sep 11 - Fri, Sep 18
American Airlines Logo
12:14 pm - 8:12 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
5h 58m1 stop Dallas/Fort Worth
American Airlines Logo
5:44 am - 10:36 amCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
6h 52m1 stop Chicago O'Hare Intl
$398American Airlines
Fri, Sep 11 - Fri, Sep 18
American Airlines Logo
7:45 am - 6:03 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
8h 18m1 stop Chicago O'Hare Intl
American Airlines Logo
5:17 pm - 9:45 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
6h 28m1 stop Dallas/Fort Worth
$398American Airlines
Fri, Aug 28 - Sun, Aug 30
United Airlines Logo
2:10 pm - 10:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
6h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
6:15 am - 1:57 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
9h 42m2 stops Chicago O'Hare Intl San Francisco
$411United Airlines
Fri, Sep 4 - Thu, Sep 10
United Airlines Logo
11:10 am - 10:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
9h 45m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 10:25 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
9h 14m1 stop Chicago O'Hare Intl
$465United Airlines
Fri, Sep 11 - Fri, Sep 18
United Airlines Logo
11:10 am - 10:55 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
9h 45m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 10:25 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
9h 14m1 stop Chicago O'Hare Intl
$467United Airlines
Fri, Sep 11 - Fri, Sep 18
United Airlines Logo
11:30 am - 8:30 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
7h 00m1 stop Denver Intl
United Airlines Logo
5:00 am - 12:03 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
9h 03m1 stop Chicago O'Hare Intl
$499United Airlines
Sat, Jan 9 - Tue, Jan 12
United Airlines Logo
11:30 am - 8:30 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
7h 00m1 stop Denver Intl
United Airlines Logo
8:00 am - 5:31 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
11h 31m2 stops Chicago O'Hare Intl Denver Intl
$505United Airlines
Sat, Jan 9 - Tue, Jan 12
American Airlines Logo
8:00 am - 4:47 pmSNA  Santa Ana J. Wayne/Orange Cnty-COU Columbia Regional
6h 47m1 stop Dallas/Fort Worth
American Airlines Logo
7:00 am - 1:30 pmCOU  Columbia Regional-SNA Santa Ana J. Wayne/Orange Cnty
8h 30m1 stop Dallas/Fort Worth
$514American Airlines
Fri, Aug 28 - Sun, Aug 30

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American Airlines flights from Santa Ana, California to Columbia, Missouri

Our best American Airlines deals on Santa Ana, California to Columbia, Missouri flight tickets
American Airlines
Sep 4
SNA1:34 pmSanta Ana J. Wayne/Orange Cnty
6h 54m
1 stop
COU10:28 pmColumbia Regional
Sep 10
COU5:44 amColumbia Regional
6h 52m
1 stop
SNA10:36 amSanta Ana J. Wayne/Orange Cnty
$328
American Airlines
Sep 11
SNA12:14 pmSanta Ana J. Wayne/Orange Cnty
5h 58m
1 stop
COU8:12 pmColumbia Regional
Sep 18
COU5:44 amColumbia Regional
6h 52m
1 stop
SNA10:36 amSanta Ana J. Wayne/Orange Cnty
$363
American Airlines
Aug 28
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 18m
1 stop
COU6:03 pmColumbia Regional
Aug 30
COU5:17 pmColumbia Regional
6h 28m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
$398

United Airlines flights from Santa Ana, California to Columbia, Missouri

Our best United Airlines deals on Santa Ana, California to Columbia, Missouri flight tickets
United Airlines
Sep 4
SNA2:10 pmSanta Ana J. Wayne/Orange Cnty
6h 45m
1 stop
COU10:55 pmColumbia Regional
Sep 10
COU6:15 amColumbia Regional
9h 42m
2 stops
SNA1:57 pmSanta Ana J. Wayne/Orange Cnty
$411
United Airlines
Sep 11
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
9h 45m
2 stops
COU10:55 pmColumbia Regional
Sep 18
COU3:11 pmColumbia Regional
9h 14m
1 stop
SNA10:25 pmSanta Ana J. Wayne/Orange Cnty
$467
United Airlines
Aug 28
SNA2:10 pmSanta Ana J. Wayne/Orange Cnty
6h 45m
1 stop
COU10:55 pmColumbia Regional
Aug 30
COU6:15 amColumbia Regional
9h 38m
2 stops
SNA1:53 pmSanta Ana J. Wayne/Orange Cnty
$590

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 9/4

1:34 pm-10:28 pm

1 stop6h 54m

Columbia Regional

Thu 9/10

5:44 am-10:36 am

1 stop6h 52m

$328
Quickest round-trip

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 9/11

12:14 pm-8:12 pm

1 stop5h 58m

Columbia Regional

Fri 9/18

5:44 am-10:36 am

1 stop6h 52m

$363

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 9/11

12:14 pm-8:12 pm

1 stop5h 58m

Columbia Regional

Fri 9/18

5:44 am-10:36 am

1 stop6h 52m

$398

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 8/28

7:45 am-6:03 pm

1 stop8h 18m

Columbia Regional

Sun 8/30

5:17 pm-9:45 pm

1 stop6h 28m

$398

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 9/4

2:10 pm-10:55 pm

1 stop6h 45m

Columbia Regional

Thu 9/10

6:15 am-1:57 pm

2 stops9h 42m

$411

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 9/11

11:10 am-10:55 pm

2 stops9h 45m

Columbia Regional

Fri 9/18

3:11 pm-10:25 pm

1 stop9h 14m

$465

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 9/11

11:10 am-10:55 pm

2 stops9h 45m

Columbia Regional

Fri 9/18

3:11 pm-10:25 pm

1 stop9h 14m

$467

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 1/9

11:30 am-8:30 pm

1 stop7h 00m

Columbia Regional

Tue 1/12

5:00 am-12:03 pm

1 stop9h 03m

$499

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 1/9

11:30 am-8:30 pm

1 stop7h 00m

Columbia Regional

Tue 1/12

8:00 am-5:31 pm

2 stops11h 31m

$505

Santa AnaColumbia

SNA Santa Ana J. Wayne/Orange Cnty - COU Columbia Regional

SNACOU

Santa Ana J. Wayne/Orange Cnty

Fri 8/28

8:00 am-4:47 pm

1 stop6h 47m

Columbia Regional

Sun 8/30

7:00 am-1:30 pm

1 stop8h 30m

$514

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Santa Ana, California to Columbia, Missouri

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Columbia, Missouri according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Columbia, Missouri (SNA to COU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Columbia, Missouri

Fastest flight time

5h 51m

Direct flights

None
The fastest flight from Santa Ana, California to Columbia, Missouri takes 5h 51m
There are no direct flights from Santa Ana, California to Columbia, Missouri. There are no popular flight routes from Santa Ana, California to Columbia, Missouri.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Columbia, Missouri

  • How far is Santa Ana J. Wayne/Orange Cnty to Columbia Regional by plane?

    There are 1459.4 mi between Santa Ana J. Wayne/Orange Cnty and Columbia Regional. 5h 51m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The required travel and health documents for your Columbia Regional Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Columbia Regional Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santa Ana, California to Columbia, Missouri?

Best airlines flying from Santa Ana, California to Columbia, Missouri

Compare and see reviews for airlines that fly from Santa Ana, California to Columbia, Missouri with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $433Free CancellationRating
7.1
11,941 reviews
Search American Airlines flights

Frequently asked questions about flying from Santa Ana, California to Columbia, Missouri

  • How do I get Price Alerts for flights from Santa Ana, California to Columbia, Missouri?

    Search flight deals from Santa Ana, California to Columbia, Missouri. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Santa Ana, California to Columbia, Missouri with momondo?

    Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore”. Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.

  • How does momondo find its flight prices?

    We show prices from over 700+ competitors with a single click. With options from airlines and OTAs from across our 30 international markets, we are able to show you a diverse range of deals to create your adventure.

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Columbia?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Columbia for you.

Can I find flights from Santa Ana to Columbia with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Columbia from Santa Ana with this policy.

How can momondo help me find flights from Santa Ana to Columbia?

momondo provides multiple filters to help you find the best flight to Columbia from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Columbia right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to Columbia flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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