Cheap flights from Santa Ana, California to Columbia from $343

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Columbia departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:44 pm - 10:40 pmSNA-COU
7h 56m1 stop
American Airlines Logo
6:42 am - 2:18 pmCOU-SNA
9h 36m1 stop
$462American Airlines
Find Deal
Sat, Nov 1 - Sat, Nov 8
American Airlines Logo
1:10 pm - 10:40 pmSNA-COU
7h 30m2 stops
American Airlines Logo
6:42 am - 2:18 pmCOU-SNA
9h 36m1 stop
$468American Airlines
Find Deal
Sat, Nov 1 - Sat, Nov 8
United Airlines Logo
7:00 am - 8:51 pmSNA-COU
11h 51m1 stop
United Airlines Logo
9:00 am - 9:23 amCOU-SNA
26h 23m1 stop
$605United Airlines
Find Deal
Mon, Oct 27 - Fri, Oct 31
United Airlines Logo
9:45 am - 3:26 pmSNA-COU
27h 41m2 stops
United Airlines Logo
3:02 pm - 8:54 amCOU-SNA
19h 52m2 stops
$626United Airlines
Find Deal
Sat, Nov 1 - Sat, Nov 8
United Airlines Logo
7:34 pm - 8:51 pmSNA-COU
23h 17m2 stops
United Airlines Logo
9:00 am - 9:23 amCOU-SNA
26h 23m1 stop
$660United Airlines
Find Deal
Mon, Oct 27 - Fri, Oct 31

American Airlines flights from Santa Ana, California to Columbia, Missouri

Our best American Airlines deals on Santa Ana, California to Columbia, Missouri flight tickets
American Airlines
Nov 1
SNA12:44 pmSanta Ana J. Wayne/Orange Cnty
7h 56m
1 stop
COU10:40 pmColumbia Regional
Nov 8
COU6:42 amColumbia Regional
9h 36m
1 stop
SNA2:18 pmSanta Ana J. Wayne/Orange Cnty
American Airlines
Nov 1
SNA1:10 pmSanta Ana J. Wayne/Orange Cnty
7h 30m
2 stops
COU10:40 pmColumbia Regional
Nov 8
COU6:42 amColumbia Regional
9h 36m
1 stop
SNA2:18 pmSanta Ana J. Wayne/Orange Cnty

United Airlines flights from Santa Ana, California to Columbia, Missouri

Our best United Airlines deals on Santa Ana, California to Columbia, Missouri flight tickets
United Airlines
Oct 27
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
11h 51m
1 stop
COU8:51 pmColumbia Regional
Oct 31
COU9:00 amColumbia Regional
26h 23m
1 stop
SNA9:23 amSanta Ana J. Wayne/Orange Cnty
United Airlines
Nov 1
SNA9:45 amSanta Ana J. Wayne/Orange Cnty
27h 41m
2 stops
COU3:26 pmColumbia Regional
Nov 8
COU3:02 pmColumbia Regional
19h 52m
2 stops
SNA8:54 amSanta Ana J. Wayne/Orange Cnty
United Airlines
Oct 27
SNA7:34 pmSanta Ana J. Wayne/Orange Cnty
23h 17m
2 stops
COU8:51 pmColumbia Regional
Oct 31
COU9:00 amColumbia Regional
26h 23m
1 stop
SNA9:23 amSanta Ana J. Wayne/Orange Cnty

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

12:44 pm-10:40 pm

1 stop7h 56m

Columbia Regional

Sat 11/8

6:42 am-2:18 pm

1 stop9h 36m

$462

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

1:10 pm-10:40 pm

2 stops7h 30m

Columbia Regional

Sat 11/8

6:42 am-2:18 pm

1 stop9h 36m

$468

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

7:00 am-8:51 pm

1 stop11h 51m

Columbia Regional

Fri 10/31

9:00 am-9:23 am

1 stop26h 23m

$605

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

9:45 am-3:26 pm

2 stops27h 41m

Columbia Regional

Sat 11/8

3:02 pm-8:54 am

2 stops19h 52m

$626

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

7:34 pm-8:51 pm

2 stops23h 17m

Columbia Regional

Fri 10/31

9:00 am-9:23 am

1 stop26h 23m

$660

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 11/18

1:33 pm-9:53 am

1 stop18h 20m

$343

Santa AnaColumbia

SNA - COU

SNACOU

Santa Ana J. Wayne/Orange Cnty

Tue 11/18

4:15 pm-2:26 pm

2 stops20h 11m

$357

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Columbia from

How to get the cheapest flight ticket from Santa Ana, California to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Columbia, Missouri?

The cheapest day to depart from Santa Ana, California to Columbia, Missouri is on a Thursday when prices can be found for as low as $480. The most expensive day to fly to Columbia, Missouri is Wednesday, with ticket prices averaging around $1,138.

What is the cheapest time of day to depart on your flight to Columbia, Missouri?

In the morning is the cheapest time of day to fly from Santa Ana, California to Columbia, Missouri when you can find flight prices for as low as $569. Flying to Columbia, Missouri in the morning is an ideal time because this is during off-peak travel hours. Flights to Columbia, Missouri are more costly at noon, with an average ticket price of $709. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Santa Ana, California to Columbia, Missouri

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Columbia, Missouri according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Columbia, Missouri (SNA to COU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Columbia, Missouri

Direct flights

None
There are no direct flights from Santa Ana, California to Columbia, Missouri. There are no popular flight routes from Santa Ana, California to Columbia, Missouri.
  • How far is Santa Ana J. Wayne/Orange Cnty to Columbia Regional by plane?

    There are 1459.4 mi between Santa Ana J. Wayne/Orange Cnty and Columbia Regional. 7h 30m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The required travel and health documents for your Columbia Regional Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Columbia Regional Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santa Ana, California to Columbia, Missouri?

Best airlines flying from Santa Ana, California to Columbia, Missouri

Compare and see reviews for airlines that fly from Santa Ana, California to Columbia, Missouri with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $392Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

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We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Columbia for you.

Can I find flights from Santa Ana to Columbia with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Columbia from Santa Ana with this policy.

How can momondo help me find flights from Santa Ana to Columbia?

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1 adult
Thu 11/13
Thu 11/20

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