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Cheap flights from San Diego to Key West from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Key West departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from San Diego to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:53 pm - 10:58 pm
SAN
-
EYW
7h 05m
1 stop
American Airlines Logo
6:45 am - 11:16 am
EYW
-
SAN
7h 31m
1 stop
$335American Airlines
Wed, May 6 - Tue, May 12
American Airlines Logo
9:12 am - 10:58 pm
SAN
-
EYW
10h 46m
2 stops
American Airlines Logo
6:45 am - 11:16 am
EYW
-
SAN
7h 31m
1 stop
$340American Airlines
Wed, May 6 - Tue, May 12
United Airlines Logo
6:15 am - 3:57 pm
SAN
-
EYW
6h 42m
1 stop
United Airlines Logo
4:38 pm - 9:26 pm
EYW
-
SAN
7h 48m
1 stop
$349United Airlines
Tue, Apr 7 - Tue, Apr 14
American Airlines Logo
12:53 pm - 10:58 pm
SAN
-
EYW
7h 05m
1 stop
American Airlines Logo
6:45 am - 11:53 am
EYW
-
SAN
8h 08m
1 stop
$355American Airlines
Tue, Apr 7 - Tue, Apr 14
American Airlines Logo
8:15 am - 10:58 pm
SAN
-
EYW
11h 43m
2 stops
American Airlines Logo
6:45 am - 11:53 am
EYW
-
SAN
8h 08m
1 stop
$360American Airlines
Tue, Apr 7 - Tue, Apr 14
Delta Logo
10:30 pm - 10:53 am
SAN
-
EYW
9h 23m
1 stop
Delta Logo
11:48 am - 7:23 pm
EYW
-
SAN
10h 35m
1 stop
$367Delta
Sat, May 9 - Fri, May 15
American Airlines Logo
6:50 am - 6:49 pm
SAN
-
EYW
8h 59m
1 stop
American Airlines Logo
4:19 pm - 11:39 pm
EYW
-
SAN
10h 20m
1 stop
$375American Airlines
Tue, Jun 2 - Wed, Jun 10
American Airlines Logo
10:45 pm - 1:05 pm
SAN
-
EYW
11h 20m
2 stops
American Airlines Logo
4:19 pm - 11:39 pm
EYW
-
SAN
10h 20m
1 stop
$400American Airlines
Tue, Jun 2 - Wed, Jun 10
Multiple Airlines Logo
12:44 pm - 11:11 am
SAN
-
EYW
19h 27m
1 stop
Multiple Airlines Logo
12:10 pm - 2:25 pm
EYW
-
SAN
29h 15m
2 stops
$405Multiple Airlines
Thu, May 7 - Fri, May 15
American Airlines Logo
10:45 pm - 1:07 pm
SAN
-
EYW
11h 22m
2 stops
American Airlines Logo
4:37 pm - 9:48 pm
EYW
-
SAN
8h 11m
1 stop
$412American Airlines
Mon, May 25 - Fri, May 29

American Airlines flights from San Diego to Key West

Our best American Airlines deals on San Diego to Key West flight tickets
American Airlines
May 6
SAN12:53 pmSan Diego
7h 05m
1 stop
EYW10:58 pmKey West
May 12
EYW6:45 amKey West
7h 31m
1 stop
SAN11:16 amSan Diego
$335
American Airlines
May 6
SAN9:12 amSan Diego
10h 46m
2 stops
EYW10:58 pmKey West
May 12
EYW6:45 amKey West
7h 31m
1 stop
SAN11:16 amSan Diego
$340
American Airlines
May 6
SAN12:53 pmSan Diego
7h 05m
1 stop
EYW10:58 pmKey West
May 12
EYW2:29 pmKey West
10h 31m
1 stop
SAN10:00 pmSan Diego
$355

United Airlines flights from San Diego to Key West

Our best United Airlines deals on San Diego to Key West flight tickets
United Airlines
Apr 7
SAN6:15 amSan Diego
6h 42m
1 stop
EYW3:57 pmKey West
Apr 14
EYW4:38 pmKey West
7h 48m
1 stop
SAN9:26 pmSan Diego
$349
United Airlines
May 2
SAN6:15 amSan Diego
6h 47m
1 stop
EYW4:02 pmKey West
May 6
EYW4:47 pmKey West
7h 38m
1 stop
SAN9:25 pmSan Diego
$479
United Airlines
May 8
SAN10:20 pmSan Diego
12h 25m
1 stop
EYW1:45 pmKey West
May 14
EYW4:47 pmKey West
7h 38m
1 stop
SAN9:25 pmSan Diego
$499

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from San Diego to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Wed 5/6

12:53 pm-10:58 pm

1 stop7h 05m

Key West

Tue 5/12

6:45 am-11:16 am

1 stop7h 31m

$335

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Wed 5/6

9:12 am-10:58 pm

2 stops10h 46m

Key West

Tue 5/12

6:45 am-11:16 am

1 stop7h 31m

$340
Quickest round-trip

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Tue 4/7

6:15 am-3:57 pm

1 stop6h 42m

Key West

Tue 4/14

4:38 pm-9:26 pm

1 stop7h 48m

$349

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Tue 4/7

12:53 pm-10:58 pm

1 stop7h 05m

Key West

Tue 4/14

6:45 am-11:53 am

1 stop8h 08m

$355

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Tue 4/7

8:15 am-10:58 pm

2 stops11h 43m

Key West

Tue 4/14

6:45 am-11:53 am

1 stop8h 08m

$360

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Sat 5/9

10:30 pm-10:53 am

1 stop9h 23m

Key West

Fri 5/15

11:48 am-7:23 pm

1 stop10h 35m

$367

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Tue 6/2

6:50 am-6:49 pm

1 stop8h 59m

Key West

Wed 6/10

4:19 pm-11:39 pm

1 stop10h 20m

$375

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Tue 6/2

10:45 pm-1:05 pm

2 stops11h 20m

Key West

Wed 6/10

4:19 pm-11:39 pm

1 stop10h 20m

$400

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 5/7

12:44 pm-11:11 am

1 stop19h 27m

Key West

Fri 5/15

12:10 pm-2:25 pm

2 stops29h 15m

$405

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Mon 5/25

10:45 pm-1:07 pm

2 stops11h 22m

Key West

Fri 5/29

4:37 pm-9:48 pm

1 stop8h 11m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from San Diego to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from San Diego to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $343. If you are unable to visit Key West during the month of September, then departing from San Diego during the month October is also very affordable. Most momondo users find prices during this month for around $370.

Can stopping save me money on San Diego to Key West flights?

You could potentially save up to 2% on your flight if you consider stops on a San Diego to Key West flight.

When to book flights from San Diego to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Key West (SAN to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Key West

Fastest flight time

6h 42m

Direct flights

None
The fastest flight from San Diego to Key West takes 6h 42m
There are no direct flights from San Diego to Key West. There are no popular flight routes from San Diego to Key West.
Search flight deals

  • How far is San Diego to Key West by plane?

    Key West is 2204.3 mi away from San Diego. Typically, this will take 6h 42m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Key West Airport?

    Prices for flights from San Diego Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from San Diego Airport to Key West Airport?

  • How old do you have to be to fly from San Diego Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Diego Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Diego to Key West?

Best airlines flying from San Diego to Key West

Compare and see reviews for airlines that fly from San Diego to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,419 reviews
Search American Airlines flights
DeltaPriceFrom $302Free CancellationRating
7.9
8,278 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Key West?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Diego to Key West. momondo saves you time and could save you money on your trip.

Can I find flights from San Diego to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Key West?

Once you have performed a search for San Diego to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Diego to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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