What is the cheapest airline that flies from San Diego to Florida Keys?

Southwest, United Airlines, and Delta are the most popular carriers operating from San Diego to Florida Keys

How many flights depart from San Diego to Florida Keys on average per week?

As of September 2026, 10 flights take off from San Diego and land in Florida Keys each week. The most common flight departure day for this route is Mon, with 50% of weekly flights taking off on this day.

When did momondo last update prices for flights from San Diego Airport to Florida Keys?

Prices for flights from San Diego Airport to Florida Keys are updated daily.

How many operators does momondo search for flights from San Diego Airport to Florida Keys?

There are 6 operators available for flights from San Diego Airport to Florida Keys as of September 2026.

How old do you have to be to fly from San Diego Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$153 Cheap Flights from San Diego to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:25 am - 12:47 amSAN San Diego-MIA Miami

15h 22m1 stop Denver Intl

5:50 am - 3:58 pmMIA Miami-SAN San Diego

13h 08m1 stop Denver Intl

$297Frontier

Thu, Oct 15 - Tue, Oct 20

6:25 am - 12:46 amSAN San Diego-MIA Miami

15h 21m1 stop Denver Intl

6:16 pm - 10:46 amMIA Miami-SAN San Diego

19h 30m1 stop Seattle/Tacoma Intl

$297Multiple Airlines

Thu, Sep 24 - Mon, Sep 28

9:03 am - 10:00 pmSAN San Diego-MIA Miami

9h 57m1 stop Dallas/Fort Worth

5:55 am - 6:09 pmMIA Miami-SAN San Diego

15h 14m2 stops Denver Intl San Francisco

$298Frontier

Sat, Sep 19 - Mon, Oct 5

9:50 pm - 10:50 amSAN San Diego-MIA Miami

10h 00m1 stop Baltimore/Washington

6:40 am - 5:15 pmMIA Miami-SAN San Diego

13h 35m1 stop Chicago Midway

$300Southwest

Mon, Oct 19 - Fri, Oct 23

8:28 pm - 5:15 pmSAN San Diego-MIA Miami

17h 47m1 stop Seattle/Tacoma Intl

5:50 am - 11:56 pmMIA Miami-SAN San Diego

21h 06m1 stop Denver Intl

$300Multiple Airlines

Fri, Oct 9 - Sun, Oct 11

10:40 pm - 11:25 amSAN San Diego-MIA Miami

9h 45m1 stop Nashville Intl

7:10 am - 7:15 pmMIA Miami-SAN San Diego

15h 05m2 stops Orlando Baltimore/Washington

$306Southwest

Mon, Oct 19 - Fri, Oct 23

10:00 pm - 12:12 pmSAN San Diego-MIA Miami

11h 12m1 stop Detroit Metropolitan Wayne County

6:00 am - 12:08 pmMIA Miami-SAN San Diego

9h 08m1 stop Minneapolis St Paul

$307Delta

Mon, Oct 19 - Sat, Oct 31

9:45 pm - 9:26 amSAN San Diego-MIA Miami

8h 41m1 stop Atlanta Hartsfield-Jackson

6:55 am - 12:25 pmMIA Miami-SAN San Diego

8h 30m1 stop Salt Lake City

$307Delta

Mon, Oct 19 - Thu, Oct 29

12:08 pm - 8:07 pmSAN San Diego-MIA Miami

4h 59mnonstop

8:20 am - 11:08 amMIA Miami-SAN San Diego

5h 48mnonstop

$308American Airlines

Fri, Jan 22 - Sun, Jan 31

10:39 pm - 6:36 amSAN San Diego-MIA Miami

4h 57mnonstop

8:20 am - 11:08 amMIA Miami-SAN San Diego

5h 48mnonstop

$308American Airlines

Fri, Jan 29 - Sun, Jan 31

Cheap last minute flights

Enter your travel dates to find the best prices.

9:03 am - 10:00 pmSAN San Diego-MIA Miami

9h 57m1 stop Dallas/Fort Worth

5:50 am - 3:58 pmMIA Miami-SAN San Diego

13h 08m1 stop Denver Intl

$303Frontier

Sat, Sep 12 - Mon, Sep 14

3:45 pm - 4:52 amSAN San Diego-MIA Miami

10h 07m1 stop Denver Intl

5:50 am - 3:58 pmMIA Miami-SAN San Diego

13h 08m1 stop Denver Intl

$303Frontier

Tue, Sep 8 - Sat, Sep 12

10:30 pm - 11:54 amSAN San Diego-MIA Miami

10h 24m1 stop Chicago O'Hare Intl

8:00 am - 1:44 pmMIA Miami-SAN San Diego

8h 44m1 stop San Francisco

$322United Airlines

Tue, Sep 8 - Wed, Sep 30

9:45 pm - 11:11 amSAN San Diego-MIA Miami

10h 26m1 stop Washington, D.C. Dulles Intl

11:30 am - 8:02 pmMIA Miami-SAN San Diego

11h 32m2 stops Houston George Bush Intcntl Los Angeles

$372United Airlines

Tue, Sep 8 - Thu, Sep 10

4:54 pm - 12:46 amSAN San Diego-MIA Miami

28h 52m1 stop Denver Intl

6:16 pm - 10:46 amMIA Miami-SAN San Diego

19h 30m1 stop Seattle/Tacoma Intl

$384Multiple Airlines

Wed, Sep 9 - Fri, Sep 11

10:45 pm - 6:53 amSAN San Diego-MIA Miami

5h 08mnonstop

12:15 pm - 6:51 pmMIA Miami-SAN San Diego

9h 36m1 stop Dallas/Fort Worth

$422American Airlines

Tue, Sep 8 - Wed, Sep 30

10:30 pm - 6:33 amSAN San Diego-MIA Miami

5h 03mnonstop

8:10 pm - 10:25 pmMIA Miami-SAN San Diego

5h 15mnonstop

$429American Airlines

Wed, Sep 9 - Sat, Sep 12

4:54 pm - 12:46 amSAN San Diego-MIA Miami

28h 52m1 stop Denver Intl

6:16 pm - 10:46 amMIA Miami-SAN San Diego

19h 30m1 stop Seattle/Tacoma Intl

$461Multiple Airlines

Wed, Sep 9 - Sun, Sep 13

6:45 am - 8:15 pmSAN San Diego-MIA Miami

10h 30m2 stops Denver Intl Nashville Intl

6:45 am - 1:00 pmMIA Miami-SAN San Diego

9h 15m2 stops Houston Hobby Phoenix Sky Harbor Intl

$503Southwest

Tue, Sep 8 - Wed, Sep 30

6:45 am - 8:05 pmSAN San Diego-MIA Miami

10h 20m2 stops Denver Intl Orlando

2:20 pm - 10:05 pmMIA Miami-SAN San Diego

10h 45m2 stops Dallas Love Field Denver Intl

$521Southwest

Wed, Sep 9 - Tue, Sep 15

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American Airlines flights from San Diego to Florida Keys

Our best American Airlines deals on San Diego to Florida Keys flight tickets

American Airlines

Oct 16

SAN9:25 pmSan Diego

7h 35m

1 stop

MIA8:00 amMiami

Nov 14

MIA8:21 amMiami

5h 27m

SAN10:48 amSan Diego

$310

American Airlines

Oct 16

SAN10:20 pmSan Diego

4h 49m

MIA6:09 amMiami

Oct 20

MIA9:30 amMiami

5h 26m

SAN11:56 amSan Diego

$325

American Airlines

Sep 28

SAN10:30 pmSan Diego

5h 03m

MIA6:33 amMiami

Oct 5

MIA9:30 amMiami

5h 26m

SAN11:56 amSan Diego

$326

Frontier flights from San Diego to Florida Keys

Our best Frontier deals on San Diego to Florida Keys flight tickets

Frontier

Sep 15

SAN4:54 pmSan Diego

28h 52m

1 stop

MIA12:46 amMiami

Oct 11

MIA5:50 amMiami

21h 06m

1 stop

SAN11:56 pmSan Diego

$297

Frontier

Sep 15

SAN4:54 pmSan Diego

28h 52m

1 stop

MIA12:46 amMiami

Oct 8

MIA9:57 amMiami

16h 59m

1 stop

SAN11:56 pmSan Diego

$298

Frontier

Oct 6

SAN6:25 amSan Diego

11h 13m

2 stops

MIA8:38 pmMiami

Oct 13

MIA5:50 amMiami

13h 08m

1 stop

SAN3:58 pmSan Diego

$299

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Thu 10/15

6:25 am-12:47 am

1 stop15h 22m

Miami

Tue 10/20

5:50 am-3:58 pm

1 stop13h 08m

$297

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Thu 9/24

6:25 am-12:46 am

1 stop15h 21m

Miami

Mon 9/28

6:16 pm-10:46 am

1 stop19h 30m

$297

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Sat 9/19

9:03 am-10:00 pm

1 stop9h 57m

Miami

Mon 10/5

5:55 am-6:09 pm

2 stops15h 14m

$298

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Mon 10/19

9:50 pm-10:50 am

1 stop10h 00m

Miami

Fri 10/23

6:40 am-5:15 pm

1 stop13h 35m

$300

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Fri 10/9

8:28 pm-5:15 pm

1 stop17h 47m

Miami

Sun 10/11

5:50 am-11:56 pm

1 stop21h 06m

$300

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Mon 10/19

10:40 pm-11:25 am

1 stop9h 45m

Miami

Fri 10/23

7:10 am-7:15 pm

2 stops15h 05m

$306

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Mon 10/19

10:00 pm-12:12 pm

1 stop11h 12m

Miami

Sat 10/31

6:00 am-12:08 pm

1 stop9h 08m

$307

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Mon 10/19

9:45 pm-9:26 am

1 stop8h 41m

Miami

Thu 10/29

6:55 am-12:25 pm

1 stop8h 30m

$307

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Fri 1/22

12:08 pm-8:07 pm

Nonstop4h 59m

Miami

Sun 1/31

8:20 am-11:08 am

Nonstop5h 48m

$308

Quickest round-trip

San DiegoMiami

SAN San Diego - MIA Miami

SANMIA

San Diego

Fri 1/29

10:39 pm-6:36 am

Nonstop4h 57m

Miami

Sun 1/31

8:20 am-11:08 am

Nonstop5h 48m

$308

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of January is another great option to travel to Florida Keys, with average flight prices from San Diego averaging around $391.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from San Diego to Florida Keys is on a Wednesday when prices can be found for as low as $509. The most expensive day to fly to Florida Keys is Monday, with ticket prices averaging around $638.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is at noon. momondo users have found flights departing from San Diego to Florida Keys at noon for as low as $522. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $587.

How far in advance should I book a flight from San Diego to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $469 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from San Diego for as low as $409 on momondo.

Can stopping save me money on San Diego to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between San Diego to Florida Keys.

Cheap San Diego to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Florida Keys

Best Price Found	$153
Fastest flight time	4h 48m
Direct flights	Every day
Airports in Florida Keys	3 airports

The best one-way flight to Florida Keys from San Diego in the past 72 hours is $153. The best round-trip flight deal from San Diego to Florida Keys found on momondo in the last 72 hours is $297.

The fastest flight from San Diego to Florida Keys takes 4h 48m

Direct flights go from San Diego to Florida Keys every day.

There are 3 airports in Florida Keys. From San Diego there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from San Diego to Florida Keys

When did momondo last update prices for flights from San Diego Airport to Florida Keys?
Prices for flights from San Diego Airport to Florida Keys are updated daily.
How many operators does momondo search for flights from San Diego Airport to Florida Keys?
There are 6 operators available for flights from San Diego Airport to Florida Keys as of September 2026.
How old do you have to be to fly from San Diego Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from San Diego to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from San Diego to Florida Keys is Boeing 737 MAX 8, representing 18.55% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 17.40%, Airbus A321neo at 10.56%, and Airbus A321-100/200 at 9.43%.

Best airlines flying from San Diego to Florida Keys

Compare and see reviews for airlines that fly from San Diego to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $312	Free Cancellation	Rating 7.1 12,042 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Florida Keys?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Florida Keys. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Florida Keys with flexible booking policies on momondo?

Flights from San Diego to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Diego to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from San Diego.

I’m not ready to book a flight from San Diego to Florida Keys right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Diego to Florida Keys flights. All you need is a valid email address and we will do the rest; it is that quick and easy.