What is the cheapest airline that flies from San Diego to Florida Keys?

Southwest, Alaska Airlines, and Delta are the most popular carriers operating from San Diego to Florida Keys

How many flights depart from San Diego to Florida Keys on average per week?

As of July 2026, 46 flights take off from San Diego and land in Florida Keys each week. The most common flight departure day for this route is Wed, with 17% of weekly flights taking off on this day.

When did momondo last update prices for flights from San Diego Airport to Florida Keys?

Prices for flights from San Diego Airport to Florida Keys are updated daily.

How many operators does momondo search for flights from San Diego Airport to Florida Keys?

There are 6 operators available for flights from San Diego Airport to Florida Keys as of July 2026.

How old do you have to be to fly from San Diego Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$132 Cheap Flights from San Diego to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:45 pm - 4:52 am

SAN

MIA

10h 07m

1 stop

10:09 pm - 8:19 am

MIA

SAN

37h 10m

2 stops

$310Frontier

Sat, Sep 5 - Sat, Sep 12

6:25 am - 5:51 am

SAN

MIA

20h 26m

1 stop

10:15 pm - 2:08 pm

MIA

SAN

18h 53m

1 stop

$311Frontier

Thu, Jul 30 - Mon, Aug 10

3:03 pm - 6:30 am

SAN

MIA

12h 27m

1 stop

6:00 am - 11:51 pm

MIA

SAN

20h 51m

1 stop

$312Frontier

Tue, Aug 4 - Fri, Aug 14

3:03 pm - 6:30 am

SAN

MIA

12h 27m

1 stop

6:00 am - 11:51 pm

MIA

SAN

20h 51m

1 stop

$313Frontier

Wed, Aug 5 - Fri, Aug 14

6:25 am - 5:51 am

SAN

MIA

20h 26m

1 stop

6:00 am - 9:05 am

MIA

SAN

30h 05m

1 stop

$314Frontier

Wed, Aug 12 - Mon, Aug 17

10:25 pm - 10:50 am

SAN

EYW

9h 25m

1 stop

6:15 pm - 11:00 pm

EYW

SAN

7h 45m

1 stop

$411Delta

Fri, Aug 14 - Tue, Aug 18

12:33 pm - 11:06 am

SAN

EYW

43h 33m

2 stops

11:07 am - 12:09 pm

EYW

SAN

28h 02m

1 stop

$442Breeze Airways

Mon, Aug 17 - Mon, Aug 24

4:22 pm - 9:44 am

SAN

EYW

14h 22m

2 stops

1:50 pm - 7:44 pm

EYW

SAN

8h 54m

1 stop

$460American Airlines

Sat, Aug 22 - Wed, Aug 26

6:15 am - 4:30 pm

SAN

EYW

7h 15m

1 stop

2:43 pm - 7:12 pm

EYW

SAN

7h 29m

1 stop

$473American Airlines

Fri, Jan 1 - Wed, Jan 6

12:37 pm - 11:19 am

SAN

EYW

19h 42m

1 stop

10:59 am - 12:40 pm

EYW

SAN

28h 41m

2 stops

$630Multiple Airlines

Thu, Oct 15 - Sun, Oct 18

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Frontier flights from San Diego to Florida Keys

Our best Frontier deals on San Diego to Florida Keys flight tickets

Frontier

Sep 5

SAN3:45 pmSan Diego

10h 07m

1 stop

MIA4:52 amMiami

Sep 12

MIA10:09 pmMiami

37h 10m

2 stops

SAN8:19 amSan Diego

$310

Frontier

Jul 30

SAN6:25 amSan Diego

20h 26m

1 stop

MIA5:51 amMiami

Aug 10

MIA10:15 pmMiami

18h 53m

1 stop

SAN2:08 pmSan Diego

$311

Frontier

Aug 4

SAN3:03 pmSan Diego

12h 27m

1 stop

MIA6:30 amMiami

Aug 14

MIA6:00 amMiami

20h 51m

1 stop

SAN11:51 pmSan Diego

$312

American Airlines flights from San Diego to Florida Keys

Our best American Airlines deals on San Diego to Florida Keys flight tickets

American Airlines

Jul 29

SAN10:25 pmSan Diego

5h 11m

MIA6:36 amMiami

Aug 5

MIA8:30 pmMiami

5h 19m

SAN10:49 pmSan Diego

$420

American Airlines

Aug 22

SAN4:22 pmSan Diego

14h 22m

2 stops

EYW9:44 amKey West

Aug 26

EYW1:50 pmKey West

8h 54m

1 stop

SAN7:44 pmSan Diego

$460

American Airlines

Jan 1

SAN6:15 amSan Diego

7h 15m

1 stop

EYW4:30 pmKey West

Jan 6

EYW2:43 pmKey West

7h 29m

1 stop

SAN7:12 pmSan Diego

$473

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 9/5

3:45 pm-4:52 am

1 stop10h 07m

Miami

Sat 9/12

10:09 pm-8:19 am

2 stops37h 10m

$310

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 7/30

6:25 am-5:51 am

1 stop20h 26m

Miami

Mon 8/10

10:15 pm-2:08 pm

1 stop18h 53m

$311

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 8/4

3:03 pm-6:30 am

1 stop12h 27m

Miami

Fri 8/14

6:00 am-11:51 pm

1 stop20h 51m

$312

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 8/5

3:03 pm-6:30 am

1 stop12h 27m

Miami

Fri 8/14

6:00 am-11:51 pm

1 stop20h 51m

$313

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 8/12

6:25 am-5:51 am

1 stop20h 26m

Miami

Mon 8/17

6:00 am-9:05 am

1 stop30h 05m

$314

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Fri 8/14

10:25 pm-10:50 am

1 stop9h 25m

Key West

Tue 8/18

6:15 pm-11:00 pm

1 stop7h 45m

$411

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Mon 8/17

12:33 pm-11:06 am

2 stops43h 33m

Key West

Mon 8/24

11:07 am-12:09 pm

1 stop28h 02m

$442

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Sat 8/22

4:22 pm-9:44 am

2 stops14h 22m

Key West

Wed 8/26

1:50 pm-7:44 pm

1 stop8h 54m

$460

Quickest round-trip

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Fri 1/1

6:15 am-4:30 pm

1 stop7h 15m

Key West

Wed 1/6

2:43 pm-7:12 pm

1 stop7h 29m

$473

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 10/15

12:37 pm-11:19 am

1 stop19h 42m

Key West

Sun 10/18

10:59 am-12:40 pm

2 stops28h 41m

$630

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of January is another great option to travel to Florida Keys, with average flight prices from San Diego averaging around $163.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from San Diego to Florida Keys is on a Wednesday when prices can be found for as low as $504. The most expensive day to fly to Florida Keys is Tuesday, with ticket prices averaging around $605.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is at noon. momondo users have found flights departing from San Diego to Florida Keys at noon for as low as $514. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the evening are often more expensive with an average ticket price of $565.

How far in advance should I book a flight from San Diego to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $464 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from San Diego for as low as $391 on momondo.

Can stopping save me money on San Diego to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between San Diego to Florida Keys.

Cheap San Diego to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Florida Keys

Fastest flight time	4h 48m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from San Diego to Florida Keys takes 4h 48m

Direct flights go from San Diego to Florida Keys every day.

There are 3 airports in Florida Keys. From San Diego there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from San Diego to Florida Keys

When did momondo last update prices for flights from San Diego Airport to Florida Keys?
Prices for flights from San Diego Airport to Florida Keys are updated daily.
How many operators does momondo search for flights from San Diego Airport to Florida Keys?
There are 6 operators available for flights from San Diego Airport to Florida Keys as of July 2026.
How old do you have to be to fly from San Diego Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from San Diego to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from San Diego to Florida Keys is Boeing 737 MAX 8, representing 17.31% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 16.84%, Airbus A321neo at 10.19%, and Airbus A321-100/200 at 8.38%.

Best airlines flying from San Diego to Florida Keys

Compare and see reviews for airlines that fly from San Diego to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $314	Free Cancellation	Rating 7.1 11,814 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Florida Keys?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Florida Keys. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Florida Keys with flexible booking policies on momondo?

Flights from San Diego to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Diego to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from San Diego.

I’m not ready to book a flight from San Diego to Florida Keys right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Diego to Florida Keys flights. All you need is a valid email address and we will do the rest; it is that quick and easy.