How many flights depart from San Diego to Florida Keys on average per week?

As of May 2026, 30 flights take off from San Diego and land in Florida Keys each week. The most common flight departure day for this route is Mon, with 17% of weekly flights taking off on this day.

What is the cheapest airline that flies from San Diego to Florida Keys?

Southwest and American Airlines are the most popular carriers operating from San Diego to Florida Keys

When did momondo last update prices for flights from San Diego Airport to Florida Keys?

Prices for flights from San Diego Airport to Florida Keys are updated daily.

How many operators does momondo search for flights from San Diego Airport to Florida Keys?

There are 7 operators available for flights from San Diego Airport to Florida Keys as of May 2026.

How old do you have to be to fly from San Diego Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$186 Cheap Flights from San Diego to Florida Keys in 2026

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Find the cheapest flights from San Diego to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:45 pm - 6:53 am

SAN

MIA

5h 08mnonstop

8:45 pm - 11:04 pm

MIA

SAN

5h 19mnonstop

$379American Airlines

Sat, Aug 29 - Sat, Sep 5

10:02 pm - 11:59 am

SAN

EYW

10h 57m

1 stop

12:40 pm - 9:11 pm

EYW

SAN

11h 31m

1 stop

$379American Airlines

Sat, Nov 7 - Wed, Nov 11

6:25 am - 11:05 pm

SAN

MIA

13h 40m

2 stops

10:06 pm - 8:58 pm

MIA

SAN

25h 52m

1 stop

$380Frontier

Wed, Aug 12 - Mon, Aug 17

10:07 pm - 7:00 am

SAN

MIA

29h 53m

1 stop

8:10 am - 8:42 am

MIA

SAN

27h 32m

2 stops

$382Frontier

Wed, May 27 - Wed, Jun 3

9:20 am - 10:50 pm

SAN

MIA

10h 30m

2 stops

12:35 pm - 10:25 pm

MIA

SAN

12h 50m

1 stop

$383Southwest

Thu, May 28 - Tue, Jun 2

10:02 pm - 11:59 am

SAN

EYW

10h 57m

1 stop

4:26 pm - 11:56 pm

EYW

SAN

10h 30m

2 stops

$384American Airlines

Sat, Nov 7 - Wed, Nov 11

12:32 pm - 8:54 pm

SAN

MIA

5h 22mnonstop

5:25 am - 10:19 am

MIA

SAN

7h 54m

1 stop

$389American Airlines

Sat, Aug 29 - Wed, Sep 9

1:38 pm - 12:44 am

SAN

MIA

32h 06m

2 stops

3:20 pm - 11:24 am

MIA

SAN

23h 04m

1 stop

$393Multiple Airlines

Fri, Jun 5 - Wed, Jun 10

12:09 pm - 10:27 am

SAN

EYW

19h 18m

1 stop

1:14 pm - 8:48 am

EYW

SAN

22h 34m

2 stops

$490Multiple Airlines

Thu, Jun 4 - Tue, Jun 9

10:40 pm - 10:58 am

SAN

EYW

9h 18m

1 stop

2:35 pm - 7:58 pm

EYW

SAN

8h 23m

1 stop

$535Delta

Fri, Sep 11 - Fri, Sep 18

Frontier flights from San Diego to Florida Keys

Our best Frontier deals on San Diego to Florida Keys flight tickets

Frontier

May 28

SAN10:07 pmSan Diego

29h 53m

1 stop

MIA7:00 amMiami

May 31

MIA6:30 amMiami

29h 12m

1 stop

SAN8:42 amSan Diego

$379

Frontier

Aug 12

SAN6:25 amSan Diego

13h 40m

2 stops

MIA11:05 pmMiami

Aug 17

MIA10:06 pmMiami

25h 52m

1 stop

SAN8:58 pmSan Diego

$380

Frontier

May 27

SAN10:07 pmSan Diego

29h 53m

1 stop

MIA7:00 amMiami

Jun 3

MIA8:10 amMiami

27h 32m

2 stops

SAN8:42 amSan Diego

$382

Southwest flights from San Diego to Florida Keys

Our best Southwest deals on San Diego to Florida Keys flight tickets

Southwest

May 28

SAN9:20 amSan Diego

10h 30m

2 stops

MIA10:50 pmMiami

Jun 2

MIA12:35 pmMiami

12h 50m

1 stop

SAN10:25 pmSan Diego

$383

Southwest

May 24

SAN10:40 pmSan Diego

11h 30m

2 stops

MIA1:10 pmMiami

May 30

MIA6:35 amMiami

11h 10m

1 stop

SAN2:45 pmSan Diego

$402

Southwest

Jun 30

SAN7:15 amSan Diego

11h 55m

1 stop

MIA10:10 pmMiami

Jul 1

MIA4:30 pmMiami

9h 25m

1 stop

SAN10:55 pmSan Diego

$404

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 8/29

10:45 pm-6:53 am

Nonstop5h 08m

Miami

Sat 9/5

8:45 pm-11:04 pm

Nonstop5h 19m

$379

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Sat 11/7

10:02 pm-11:59 am

1 stop10h 57m

Key West

Wed 11/11

12:40 pm-9:11 pm

1 stop11h 31m

$379

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 8/12

6:25 am-11:05 pm

2 stops13h 40m

Miami

Mon 8/17

10:06 pm-8:58 pm

1 stop25h 52m

$380

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 5/27

10:07 pm-7:00 am

1 stop29h 53m

Miami

Wed 6/3

8:10 am-8:42 am

2 stops27h 32m

$382

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 5/28

9:20 am-10:50 pm

2 stops10h 30m

Miami

Tue 6/2

12:35 pm-10:25 pm

1 stop12h 50m

$383

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Sat 11/7

10:02 pm-11:59 am

1 stop10h 57m

Key West

Wed 11/11

4:26 pm-11:56 pm

2 stops10h 30m

$384

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 8/29

12:32 pm-8:54 pm

Nonstop5h 22m

Miami

Wed 9/9

5:25 am-10:19 am

1 stop7h 54m

$389

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Fri 6/5

1:38 pm-12:44 am

2 stops32h 06m

Miami

Wed 6/10

3:20 pm-11:24 am

1 stop23h 04m

$393

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 6/4

12:09 pm-10:27 am

1 stop19h 18m

Key West

Tue 6/9

1:14 pm-8:48 am

2 stops22h 34m

$490

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Fri 9/11

10:40 pm-10:58 am

1 stop9h 18m

Key West

Fri 9/18

2:35 pm-7:58 pm

1 stop8h 23m

$535

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of July is another great option to travel to Florida Keys, with average flight prices from San Diego averaging around $138.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from San Diego to Florida Keys is on a Wednesday when prices can be found for as low as $524. The most expensive day to fly to Florida Keys is Monday, with ticket prices averaging around $580.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is at noon. momondo users have found flights departing from San Diego to Florida Keys at noon for as low as $516. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $574.

How far in advance should I book a flight from San Diego to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $463 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from San Diego for as low as $406 on momondo.

Can stopping save me money on San Diego to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between San Diego to Florida Keys.

Cheap San Diego to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Florida Keys

Fastest flight time	4h 49m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from San Diego to Florida Keys takes 4h 49m

Direct flights go from San Diego to Florida Keys every day.

There are 3 airports in Florida Keys. From San Diego there are direct flights to Miami (MIA).

Search flight deals

Frequently asked questions about flying from San Diego to Florida Keys

When did momondo last update prices for flights from San Diego Airport to Florida Keys?
Prices for flights from San Diego Airport to Florida Keys are updated daily.
How many operators does momondo search for flights from San Diego Airport to Florida Keys?
There are 7 operators available for flights from San Diego Airport to Florida Keys as of May 2026.
How old do you have to be to fly from San Diego Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from San Diego to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from San Diego to Florida Keys is Boeing 737 MAX 8, representing 20.17% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 17.23%, Airbus A321neo at 10.86%, and Boeing 737-900 at 7.75%.

Best airlines flying from San Diego to Florida Keys

Compare and see reviews for airlines that fly from San Diego to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $302	Free Cancellation	Rating 7.9 8,453 reviews		Search Delta flights
American Airlines	PriceFrom $314	Free Cancellation	Rating 7.1 11,654 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Florida Keys?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Florida Keys. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Florida Keys with flexible booking policies on momondo?

Flights from San Diego to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Diego to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from San Diego.

I’m not ready to book a flight from San Diego to Florida Keys right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Diego to Florida Keys flights. All you need is a valid email address and we will do the rest; it is that quick and easy.