What is the cheapest airline that flies from San Diego to Florida Keys?

Alaska Airlines, Delta, and United Airlines are the most popular carriers operating from San Diego to Florida Keys

How many flights depart from San Diego to Florida Keys on average per week?

As of March 2026, 39 flights take off from San Diego and land in Florida Keys each week. The most common flight departure day for this route is Fri, with 18% of weekly flights taking off on this day.

When did momondo last update prices for flights from San Diego Airport to Florida Keys?

Prices for flights from San Diego Airport to Florida Keys are updated daily.

How many operators does momondo search for flights from San Diego Airport to Florida Keys?

There are 7 operators available for flights from San Diego Airport to Florida Keys as of March 2026.

How old do you have to be to fly from San Diego Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$175 Cheap Flights from San Diego to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from San Diego to Florida Keys

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:37 am - 5:33 am

SAN

MIA

16h 56m

1 stop

8:10 pm - 9:12 pm

MIA

SAN

28h 02m

1 stop

$370Frontier

Thu, May 28 - Fri, May 29

8:47 am - 5:49 am

SAN

MIA

18h 02m

1 stop

12:59 pm - 11:26 pm

MIA

SAN

13h 27m

1 stop

$372Frontier

Thu, Apr 9 - Sun, Apr 12

9:35 am - 10:00 pm

SAN

MIA

9h 25m

2 stops

3:00 pm - 9:30 pm

MIA

SAN

9h 30m

2 stops

$373Southwest

Mon, Apr 27 - Wed, May 6

10:30 pm - 10:46 am

SAN

EYW

9h 16m

1 stop

11:45 am - 6:39 pm

EYW

SAN

9h 54m

1 stop

$375Delta

Sun, Apr 19 - Tue, Apr 21

1:38 pm - 5:38 am

SAN

MIA

13h 00m

2 stops

5:05 am - 11:24 am

MIA

SAN

9h 19m

1 stop

$375Multiple Airlines

Thu, May 14 - Sun, May 17

6:25 am - 9:17 pm

SAN

MIA

11h 52m

1 stop

5:05 am - 11:24 am

MIA

SAN

9h 19m

1 stop

$377Multiple Airlines

Sat, May 23 - Sun, May 31

10:40 pm - 5:30 pm

SAN

MIA

15h 50m

2 stops

3:00 pm - 9:30 pm

MIA

SAN

9h 30m

2 stops

$378Southwest

Thu, Apr 30 - Tue, May 5

10:05 pm - 6:00 am

SAN

MIA

4h 55mnonstop

8:40 am - 11:16 am

MIA

SAN

5h 36mnonstop

$379American Airlines

Sat, May 2 - Sat, May 9

12:32 pm - 8:50 pm

SAN

MIA

5h 18mnonstop

7:40 pm - 10:13 pm

MIA

SAN

5h 33mnonstop

$380American Airlines

Sat, Aug 29 - Wed, Sep 9

9:45 pm - 10:46 am

SAN

EYW

10h 01m

1 stop

6:18 pm - 11:25 pm

EYW

SAN

8h 07m

1 stop

$399Delta

Tue, Apr 28 - Sat, May 2

Alaska Airlines flights from San Diego to Florida Keys

Our best Alaska Airlines deals on San Diego to Florida Keys flight tickets

Alaska Airlines

Apr 18

SAN9:07 pmSan Diego

15h 37m

1 stop

MIA3:44 pmMiami

Apr 21

MIA4:44 pmMiami

10h 18m

1 stop

SAN12:02 amSan Diego

$417

Alaska Airlines

Apr 11

SAN7:00 amSan Diego

27h 49m

3 stops

EYW1:49 pmKey West

Apr 15

EYW12:04 pmKey West

24h 47m

2 stops

SAN9:51 amSan Diego

$2,048

Frontier flights from San Diego to Florida Keys

Our best Frontier deals on San Diego to Florida Keys flight tickets

Frontier

May 28

SAN9:37 amSan Diego

16h 56m

1 stop

MIA5:33 amMiami

May 29

MIA8:10 pmMiami

28h 02m

1 stop

SAN9:12 pmSan Diego

$370

Frontier

Apr 4

SAN9:28 pmSan Diego

29h 21m

1 stop

MIA5:49 amMiami

Apr 7

MIA7:00 amMiami

20h 02m

1 stop

SAN12:02 amSan Diego

$371

Frontier

Apr 9

SAN8:47 amSan Diego

18h 02m

1 stop

MIA5:49 amMiami

Apr 12

MIA12:59 pmMiami

13h 27m

1 stop

SAN11:26 pmSan Diego

$372

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 5/28

9:37 am-5:33 am

1 stop16h 56m

Miami

Fri 5/29

8:10 pm-9:12 pm

1 stop28h 02m

$370

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 4/9

8:47 am-5:49 am

1 stop18h 02m

Miami

Sun 4/12

12:59 pm-11:26 pm

1 stop13h 27m

$372

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 4/27

9:35 am-10:00 pm

2 stops9h 25m

Miami

Wed 5/6

3:00 pm-9:30 pm

2 stops9h 30m

$373

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Sun 4/19

10:30 pm-10:46 am

1 stop9h 16m

Key West

Tue 4/21

11:45 am-6:39 pm

1 stop9h 54m

$375

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 5/14

1:38 pm-5:38 am

2 stops13h 00m

Miami

Sun 5/17

5:05 am-11:24 am

1 stop9h 19m

$375

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 5/23

6:25 am-9:17 pm

1 stop11h 52m

Miami

Sun 5/31

5:05 am-11:24 am

1 stop9h 19m

$377

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 4/30

10:40 pm-5:30 pm

2 stops15h 50m

Miami

Tue 5/5

3:00 pm-9:30 pm

2 stops9h 30m

$378

Quickest round-trip

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 5/2

10:05 pm-6:00 am

Nonstop4h 55m

Miami

Sat 5/9

8:40 am-11:16 am

Nonstop5h 36m

$379

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 8/29

12:32 pm-8:50 pm

Nonstop5h 18m

Miami

Wed 9/9

7:40 pm-10:13 pm

Nonstop5h 33m

$380

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Tue 4/28

9:45 pm-10:46 am

1 stop10h 01m

Key West

Sat 5/2

6:18 pm-11:25 pm

1 stop8h 07m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Florida Keys?

The month of October is another great option to travel to Florida Keys, with average flight prices from San Diego averaging around $409.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from San Diego to Florida Keys is on a Saturday when prices can be found for as low as $515. The most expensive day to fly to Florida Keys is Monday, with ticket prices averaging around $575.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is at noon. momondo users have found flights departing from San Diego to Florida Keys at noon for as low as $515. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $554.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $450 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from San Diego for as low as $382 on momondo.

Can stopping save me money on San Diego to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between San Diego to Florida Keys.

Cheap San Diego to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Florida Keys

Fastest flight time	4h 51m
Direct flights	Every day
Airports in Florida Keys	3 airports

The fastest flight from San Diego to Florida Keys takes 4h 51m

Direct flights go from San Diego to Florida Keys every day.

There are 3 airports in Florida Keys. From San Diego there are direct flights to Miami (MIA).

Search flight deals

When did momondo last update prices for flights from San Diego Airport to Florida Keys?
Prices for flights from San Diego Airport to Florida Keys are updated daily.
How many operators does momondo search for flights from San Diego Airport to Florida Keys?
There are 7 operators available for flights from San Diego Airport to Florida Keys as of March 2026.
How old do you have to be to fly from San Diego Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from San Diego to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from San Diego to Florida Keys is Boeing 737 MAX 8, representing 18.97% of all bookings. The subsequent popular models are Boeing 737-800 Passenger/BBJ2 (winglets) at 16.62%, Airbus A321neo at 11.91%, and Boeing 737-900 at 7.35%.

Best airlines flying from San Diego to Florida Keys

Compare and see reviews for airlines that fly from San Diego to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $309	Free Cancellation	Rating 7.1 11,521 reviews		Search American Airlines flights
Delta	PriceFrom $338	Free Cancellation	Rating 7.9 8,359 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Florida Keys?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Florida Keys. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Florida Keys with flexible booking policies on momondo?

Flights from San Diego to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Diego to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from San Diego.

I’m not ready to book a flight from San Diego to Florida Keys right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Diego to Florida Keys flights. All you need is a valid email address and we will do the rest; it is that quick and easy.