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Cheap flights from San Diego to Florida Keys from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Florida Keys departing on 2/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to Florida Keys

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:15 am - 5:55 pm
SAN
-
EYW
8h 40m1 stop
American Airlines Logo
4:37 pm - 11:09 pm
EYW
-
SAN
9h 32m1 stop
$265American Airlines
jue., ene. 1 - jue., ene. 8
American Airlines Logo
6:15 am - 5:55 pm
SAN
-
EYW
8h 40m1 stop
American Airlines Logo
2:43 pm - 9:58 pm
EYW
-
SAN
10h 15m2 stops
$270American Airlines
jue., ene. 1 - jue., ene. 8
American Airlines Logo
6:15 am - 7:10 pm
SAN
-
EYW
9h 55m2 stops
American Airlines Logo
6:06 am - 2:14 pm
EYW
-
SAN
11h 08m2 stops
$275American Airlines
mar., feb. 3 - mar., feb. 10
Frontier Logo
11:49 am - 5:48 pm
SAN
-
MIA
26h 59m2 stops
Frontier Logo
7:00 am - 12:08 am
MIA
-
SAN
20h 08m1 stop
$276Frontier
jue., ene. 22 - lun., ene. 26
Delta Logo
6:15 am - 5:45 pm
SAN
-
MIA
8h 30m1 stop
Delta Logo
7:50 am - 1:48 pm
MIA
-
SAN
8h 58m1 stop
$277Delta
lun., ene. 26 - dom., feb. 1
Frontier Logo
1:06 pm - 5:35 am
SAN
-
MIA
13h 29m1 stop
Frontier Logo
7:05 am - 12:11 pm
MIA
-
SAN
8h 06m1 stop
$278Frontier
jue., dic. 25 - mié., dic. 31
Frontier Logo
6:25 am - 6:00 pm
SAN
-
MIA
8h 35m1 stop
Frontier Logo
7:05 am - 9:58 pm
MIA
-
SAN
17h 53m1 stop
$279Frontier
mar., dic. 30 - mar., ene. 6
Multiple Airlines Logo
1:06 pm - 9:04 pm
SAN
-
MIA
28h 58m2 stops
Multiple Airlines Logo
7:05 am - 9:58 pm
MIA
-
SAN
17h 53m1 stop
$280Multiple Airlines
mar., dic. 23 - mar., ene. 6
Multiple Airlines Logo
6:45 am - 11:43 pm
SAN
-
MIA
13h 58m1 stop
Multiple Airlines Logo
7:00 am - 11:16 pm
MIA
-
SAN
19h 16m2 stops
$281Multiple Airlines
vie., ene. 2 - sáb., ene. 10
Frontier Logo
6:44 am - 11:43 pm
SAN
-
MIA
13h 59m1 stop
Frontier Logo
5:40 pm - 12:24 am
MIA
-
SAN
9h 44m1 stop
$282Frontier
sáb., ene. 3 - jue., ene. 15

Delta flights from San Diego to Florida Keys

Our best Delta deals on San Diego to Florida Keys flight tickets
Delta
Jan 26
SAN6:15 amSan Diego
8h 30m
1 stop
MIA5:45 pmMiami
Feb 1
MIA7:50 amMiami
8h 58m
1 stop
SAN1:48 pmSan Diego
$277
Find similar
Delta
Jan 22
SAN2:20 pmSan Diego
7h 31m
1 stop
MIA12:51 amMiami
Jan 25
MIA7:50 amMiami
8h 43m
1 stop
SAN1:33 pmSan Diego
$297
Find similar
Delta
Mar 6
SAN2:15 pmSan Diego
7h 38m
1 stop
MIA12:53 amMiami
Mar 17
MIA3:17 pmMiami
8h 19m
1 stop
SAN8:36 pmSan Diego
$318
Find similar

Frontier flights from San Diego to Florida Keys

Our best Frontier deals on San Diego to Florida Keys flight tickets
Frontier
Jan 22
SAN11:49 amSan Diego
26h 59m
2 stops
MIA5:48 pmMiami
Jan 26
MIA7:00 amMiami
20h 08m
1 stop
SAN12:08 amSan Diego
$276
Find similar
Frontier
Dec 15
SAN6:25 amSan Diego
13h 53m
1 stop
MIA11:18 pmMiami
Dec 30
MIA9:05 pmMiami
29h 54m
2 stops
SAN11:59 pmSan Diego
$277
Find similar
Frontier
Dec 25
SAN1:06 pmSan Diego
13h 29m
1 stop
MIA5:35 amMiami
Dec 31
MIA7:05 amMiami
8h 06m
1 stop
SAN12:11 pmSan Diego
$278
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 8, 2025.
Use the filters below to find and compare flights from San Diego to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoKey West

SAN - EYW

SANEYW

San Diego

jue. 1/1

6:15 am-5:55 pm

1 stop8h 40m

Key West

jue. 1/8

4:37 pm-11:09 pm

1 stop9h 32m

$265

San DiegoKey West

SAN - EYW

SANEYW

San Diego

jue. 1/1

6:15 am-5:55 pm

1 stop8h 40m

Key West

jue. 1/8

2:43 pm-9:58 pm

2 stops10h 15m

$270

San DiegoKey West

SAN - EYW

SANEYW

San Diego

mar. 2/3

6:15 am-7:10 pm

2 stops9h 55m

Key West

mar. 2/10

6:06 am-2:14 pm

2 stops11h 08m

$275

San DiegoMiami

SAN - MIA

SANMIA

San Diego

jue. 1/22

11:49 am-5:48 pm

2 stops26h 59m

Miami

lun. 1/26

7:00 am-12:08 am

1 stop20h 08m

$276

San DiegoMiami

SAN - MIA

SANMIA

San Diego

lun. 1/26

6:15 am-5:45 pm

1 stop8h 30m

Miami

dom. 2/1

7:50 am-1:48 pm

1 stop8h 58m

$277

San DiegoMiami

SAN - MIA

SANMIA

San Diego

jue. 12/25

1:06 pm-5:35 am

1 stop13h 29m

Miami

mié. 12/31

7:05 am-12:11 pm

1 stop8h 06m

$278

San DiegoMiami

SAN - MIA

SANMIA

San Diego

mar. 12/30

6:25 am-6:00 pm

1 stop8h 35m

Miami

mar. 1/6

7:05 am-9:58 pm

1 stop17h 53m

$279

San DiegoMiami

SAN - MIA

SANMIA

San Diego

mar. 12/23

1:06 pm-9:04 pm

2 stops28h 58m

Miami

mar. 1/6

7:05 am-9:58 pm

1 stop17h 53m

$280

San DiegoMiami

SAN - MIA

SANMIA

San Diego

vie. 1/2

6:45 am-11:43 pm

1 stop13h 58m

Miami

sáb. 1/10

7:00 am-11:16 pm

2 stops19h 16m

$281

San DiegoMiami

SAN - MIA

SANMIA

San Diego

sáb. 1/3

6:44 am-11:43 pm

1 stop13h 59m

Miami

jue. 1/15

5:40 pm-12:24 am

1 stop9h 44m

$282

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from San Diego to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of October is another great option to travel to Florida Keys, with average flight prices from San Diego averaging around $407.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from San Diego to Florida Keys is on a Friday when prices can be found for as low as $517. The most expensive day to fly to Florida Keys is Thursday, with ticket prices averaging around $559.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from San Diego to Florida Keys in the afternoon for as low as $286. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the evening are often more expensive with an average ticket price of $560.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $446 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from San Diego for as low as $405 on momondo.

Can stopping save me money on San Diego to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between San Diego to Florida Keys.

Cheap San Diego to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Florida Keys

Fastest flight time

4h 42m

Direct flights

Every day

Airports in Florida Keys

1 airport
The fastest flight from San Diego to Florida Keys takes 4h 42m
Direct flights go from San Diego to Florida Keys every day.
There is 1 airport near Florida Keys: Miami (MIA)
Search flight deals

  • When did momondo last update prices for flights from San Diego Airport to Florida Keys?

    Prices for flights from San Diego Airport to Florida Keys are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Florida Keys?

  • How old do you have to be to fly from San Diego Airport to Florida Keys?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from San Diego to Florida Keys?

Best airlines flying from San Diego to Florida Keys

Compare and see reviews for airlines that fly from San Diego to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $278Free CancellationRating
7.9
8,013 reviews
Search Delta flights
American AirlinesPriceFrom $314Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Florida Keys?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Florida Keys. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Florida Keys with flexible booking policies on momondo?

Flights from San Diego to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Diego to Florida Keys?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florida Keys from San Diego.

I’m not ready to book a flight from San Diego to Florida Keys right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Diego to Florida Keys flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Florida Keys trip

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mié. 1/7
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Find better results for your trip to Florida Keys

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