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Cheap flights from San Antonio to Florence from $873

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Florence departing on 3/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Antonio to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:14 am - 5:50 pm
SAT
-
FLO
6h 36m
1 stop
American Airlines Logo
5:16 am - 9:20 am
FLO
-
SAT
5h 04m
1 stop
$873American Airlines
Sun, Mar 22 - Thu, Mar 26
American Airlines Logo
5:53 pm - 11:57 pm
SAT
-
FLO
5h 04m
1 stop
American Airlines Logo
5:16 am - 12:50 pm
FLO
-
SAT
8h 34m
2 stops
$878American Airlines
Sun, Mar 22 - Thu, Mar 26
American Airlines Logo
7:00 am - 5:50 pm
SAT
-
FLO
9h 50m
2 stops
American Airlines Logo
5:16 am - 2:18 pm
FLO
-
SAT
10h 02m
2 stops
$956American Airlines
Sun, Mar 22 - Thu, Mar 26

American Airlines flights from San Antonio to Florence, South Carolina

Our best American Airlines deals on San Antonio to Florence, South Carolina flight tickets
American Airlines
Mar 22
SAT10:14 amSan Antonio
6h 36m
1 stop
FLO5:50 pmFlorence
Mar 26
FLO5:16 amFlorence
5h 04m
1 stop
SAT9:20 amSan Antonio
$873
American Airlines
Mar 22
SAT5:53 pmSan Antonio
5h 04m
1 stop
FLO11:57 pmFlorence
Mar 26
FLO5:16 amFlorence
8h 34m
2 stops
SAT12:50 pmSan Antonio
$878
American Airlines
Mar 22
SAT7:00 amSan Antonio
9h 50m
2 stops
FLO5:50 pmFlorence
Mar 26
FLO5:16 amFlorence
10h 02m
2 stops
SAT2:18 pmSan Antonio
$956

momondo Fare Finder

 
Customize your flight search to find flights from San Antonio to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 9, 2026.
Use the filters below to find and compare flights from San Antonio to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San AntonioFlorence

SAT - FLO

SATFLO

San Antonio

Sun 3/22

10:14 am-5:50 pm

1 stop6h 36m

Florence

Thu 3/26

5:16 am-9:20 am

1 stop5h 04m

$873

San AntonioFlorence

SAT - FLO

SATFLO

San Antonio

Sun 3/22

5:53 pm-11:57 pm

1 stop5h 04m

Florence

Thu 3/26

5:16 am-12:50 pm

2 stops8h 34m

$878

San AntonioFlorence

SAT - FLO

SATFLO

San Antonio

Sun 3/22

7:00 am-5:50 pm

2 stops9h 50m

Florence

Thu 3/26

5:16 am-2:18 pm

2 stops10h 02m

$956

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from San Antonio to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Florence, South Carolina from San Antonio according to our data. American Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from San Antonio to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from San Antonio to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Antonio to Florence, South Carolina (SAT to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to Florence, South Carolina

Fastest flight time

6h 36m

Direct flights

None
The fastest flight from San Antonio to Florence, South Carolina takes 6h 36m
There are no direct flights from San Antonio to Florence, South Carolina. There are no popular flight routes from San Antonio to Florence, South Carolina.
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  • How far is San Antonio to Florence by plane?

    Florence is 1145.4 mi away from San Antonio. 6h 36m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Antonio Airport to Florence Airport?

    Prices for flights from San Antonio Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from San Antonio Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Antonio Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to Florence?

It is quick and easy to find San Antonio to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from San Antonio to Florence with flexible booking policies on momondo?

All flight searches from San Antonio to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Antonio to Florence?

Once you have performed a search for San Antonio to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Antonio to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from San Antonio. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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