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Cheap flights from Rochester to Florence from $503

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Rochester to Florence departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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American Airlines Logo
5:39 pm - 11:38 pmROC-FLO
5h 59m1 stop
American Airlines Logo
5:13 am - 10:46 amFLO-ROC
5h 33m1 stop
$503American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:39 pm - 11:38 pmROC-FLO
5h 59m1 stop
American Airlines Logo
2:30 pm - 11:32 pmFLO-ROC
9h 02m2 stops
$508American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:34 pm - 11:38 pmROC-FLO
6h 04m2 stops
American Airlines Logo
11:09 am - 10:21 pmFLO-ROC
11h 12m2 stops
$513American Airlines
Find Deal
Wed, Mar 25 - Sat, Mar 28

American Airlines flights from Rochester to Florence, South Carolina

Our best American Airlines deals on Rochester to Florence, South Carolina flight tickets
American Airlines
Mar 25
ROC5:39 pmGreater Rochester Intl
5h 59m
1 stop
FLO11:38 pmFlorence
Mar 28
FLO5:13 amFlorence
5h 33m
1 stop
ROC10:46 amGreater Rochester Intl
$503
Find similar
American Airlines
Mar 25
ROC5:39 pmGreater Rochester Intl
5h 59m
1 stop
FLO11:38 pmFlorence
Mar 28
FLO2:30 pmFlorence
9h 02m
2 stops
ROC11:32 pmGreater Rochester Intl
$508
Find similar
American Airlines
Mar 25
ROC5:34 pmGreater Rochester Intl
6h 04m
2 stops
FLO11:38 pmFlorence
Mar 28
FLO11:09 amFlorence
11h 12m
2 stops
ROC10:21 pmGreater Rochester Intl
$513
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Rochester to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Rochester to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Wed 3/25

5:39 pm-11:38 pm

1 stop5h 59m

Florence

Sat 3/28

5:13 am-10:46 am

1 stop5h 33m

$503

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Wed 3/25

5:39 pm-11:38 pm

1 stop5h 59m

Florence

Sat 3/28

2:30 pm-11:32 pm

2 stops9h 02m

$508

RochesterFlorence

ROC - FLO

ROCFLO

Greater Rochester Intl

Wed 3/25

5:34 pm-11:38 pm

2 stops6h 04m

Florence

Sat 3/28

11:09 am-10:21 pm

2 stops11h 12m

$513

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Rochester to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Florence, South Carolina from Rochester according to our data. American Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 9 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Rochester to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Rochester to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Rochester to Florence, South Carolina (ROC to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester to Florence, South Carolina

Direct flights

None
There are no direct flights from Rochester to Florence, South Carolina. There are no popular flight routes from Rochester to Florence, South Carolina.
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  • How far is Greater Rochester Intl to Florence by plane?

    Greater Rochester Intl and Florence are 629.3 mi apart from one another. 5h 59m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Greater Rochester Intl Airport to Florence Airport?

    Prices for flights from Greater Rochester Intl Airport to Florence Airport are updated daily.

  • How many operators does momondo search for flights from Greater Rochester Intl Airport to Florence Airport?

  • How old do you have to be to fly from Greater Rochester Intl Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greater Rochester Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Rochester to Florence, South Carolina?

Best airlines flying from Rochester to Florence, South Carolina

Compare and see reviews for airlines that fly from Rochester to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $418Free CancellationRating
7.2
11,037 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to Florence?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Rochester to Florence. momondo saves you time and could save you money on your trip.

Can I find flights from Rochester to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Rochester with this policy.

How can momondo help me find flights from Rochester to Florence?

Once all potential Rochester to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Rochester to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Rochester to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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