What airlines fly to Missouri?

Delta, American Airlines and United Airlines are the top three most popular airlines that fly to Missouri from Roanoke according to our data. Delta is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 3 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Roanoke to Missouri?

United Airlines, American Airlines, and Delta are the most popular carriers operating from Roanoke to Missouri

When did momondo last update prices for flights from Roanoke Airport to Missouri?

Prices for flights from Roanoke Airport to Missouri are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to Missouri?

As of October 2026, there are 3 operators available to choose from for flights from Roanoke Airport to Missouri.

How old do you have to be to fly from Roanoke Airport to Missouri?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$263 Cheap Flights from Roanoke to Missouri in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:52 pm - 10:50 pmROA Roanoke-MCI Kansas City

6h 58m1 stop Chicago O'Hare Intl

9:12 am - 4:22 pmMCI Kansas City-ROA Roanoke

6h 10m1 stop Chicago O'Hare Intl

$339American Airlines

Thu, Nov 5 - Tue, Nov 10

6:40 am - 1:05 pmROA Roanoke-MCI Kansas City

7h 25m1 stop Charlotte Douglas

6:03 am - 1:53 pmMCI Kansas City-ROA Roanoke

6h 50m1 stop Philadelphia

$339American Airlines

Sat, Oct 24 - Sun, Nov 1

6:54 pm - 11:55 pmROA Roanoke-MCI Kansas City

6h 01m1 stop Atlanta Hartsfield-Jackson

10:32 am - 6:14 pmMCI Kansas City-ROA Roanoke

6h 42m1 stop Atlanta Hartsfield-Jackson

$339Delta

Fri, Nov 13 - Sun, Nov 15

11:30 am - 3:05 pmROA Roanoke-MCI Kansas City

4h 35m1 stop Atlanta Hartsfield-Jackson

5:20 am - 10:45 amMCI Kansas City-ROA Roanoke

4h 25m1 stop Atlanta Hartsfield-Jackson

$339Delta

Tue, Dec 22 - Tue, Dec 29

10:40 am - 5:34 pmROA Roanoke-MCI Kansas City

7h 54m1 stop Chicago O'Hare Intl

5:50 pm - 11:44 pmMCI Kansas City-ROA Roanoke

4h 54m1 stop Washington, D.C. Dulles Intl

$339United Airlines

Sat, Nov 7 - Mon, Nov 9

2:55 pm - 7:55 pmROA Roanoke-MCI Kansas City

6h 00m1 stop Washington, D.C. Dulles Intl

1:09 pm - 9:01 pmMCI Kansas City-ROA Roanoke

6h 52m1 stop Chicago O'Hare Intl

$339United Airlines

Thu, Nov 5 - Sat, Nov 7

6:00 am - 9:35 amROA Roanoke-MCI Kansas City

4h 35m1 stop Atlanta Hartsfield-Jackson

5:26 pm - 12:23 amMCI Kansas City-ROA Roanoke

5h 57m1 stop Atlanta Hartsfield-Jackson

$339Delta

Sat, Mar 27 - Mon, Mar 29

9:21 am - 1:05 pmROA Roanoke-MCI Kansas City

4h 44m1 stop Charlotte Douglas

9:12 am - 4:22 pmMCI Kansas City-ROA Roanoke

6h 10m1 stop Chicago O'Hare Intl

$339American Airlines

Sat, Oct 24 - Sun, Nov 1

10:40 am - 5:34 pmROA Roanoke-MCI Kansas City

7h 54m1 stop Chicago O'Hare Intl

11:33 am - 7:07 pmMCI Kansas City-ROA Roanoke

6h 34m1 stop Washington, D.C. Dulles Intl

$339United Airlines

Thu, Nov 5 - Sat, Nov 7

1:03 pm - 5:42 pmROA Roanoke-MCI Kansas City

5h 39m1 stop Charlotte Douglas

6:03 am - 1:53 pmMCI Kansas City-ROA Roanoke

6h 50m1 stop Philadelphia

$339American Airlines

Sat, Oct 24 - Sun, Nov 1

Cheap last minute flights

Enter your travel dates to find the best prices.

11:15 am - 5:30 pmROA Roanoke-STL Lambert-St Louis

7h 15m1 stop Charlotte Douglas

5:15 am - 10:37 amSTL Lambert-St Louis-ROA Roanoke

4h 22m1 stop Charlotte Douglas

$444American Airlines

Fri, Oct 2 - Sun, Oct 4

6:49 am - 12:13 pmROA Roanoke-STL Lambert-St Louis

6h 24m1 stop Chicago O'Hare Intl

3:11 pm - 10:59 pmSTL Lambert-St Louis-ROA Roanoke

6h 48m1 stop Chicago O'Hare Intl

$444United Airlines

Fri, Oct 2 - Sun, Oct 4

7:20 am - 5:45 pmROA Roanoke-STL Lambert-St Louis

11h 25m2 stops New York LaGuardia Atlanta Hartsfield-Jackson

6:54 pm - 11:59 pmSTL Lambert-St Louis-ROA Roanoke

4h 05m1 stop Atlanta Hartsfield-Jackson

$698Delta

Fri, Oct 2 - Sun, Oct 4

7:20 am - 5:45 pmROA Roanoke-STL Lambert-St Louis

11h 25m2 stops New York LaGuardia Atlanta Hartsfield-Jackson

6:54 pm - 11:59 pmSTL Lambert-St Louis-ROA Roanoke

4h 05m1 stop Atlanta Hartsfield-Jackson

$748Delta

Fri, Oct 2 - Sun, Oct 4

7:20 am - 3:54 pmROA Roanoke-STL Lambert-St Louis

9h 34m2 stops New York LaGuardia Atlanta Hartsfield-Jackson

11:21 am - 10:48 pmSTL Lambert-St Louis-ROA Roanoke

10h 27m2 stops Minneapolis St Paul New York LaGuardia

$822Delta

Fri, Oct 2 - Sun, Oct 4

2:04 pm - 6:43 pmROA Roanoke-STL Lambert-St Louis

5h 39m1 stop Charlotte Douglas

9:27 am - 3:47 pmSTL Lambert-St Louis-ROA Roanoke

5h 20m1 stop Charlotte Douglas

$838American Airlines

Tue, Oct 6 - Fri, Oct 9

5:48 pm - 12:19 amROA Roanoke-STL Lambert-St Louis

7h 31m2 stops New York LaGuardia Chicago O'Hare Intl

12:49 pm - 5:45 pmSTL Lambert-St Louis-ROA Roanoke

3h 56m1 stop Charlotte Douglas

$843American Airlines

Tue, Oct 6 - Fri, Oct 9

7:20 am - 3:54 pmROA Roanoke-STL Lambert-St Louis

9h 34m2 stops New York LaGuardia Atlanta Hartsfield-Jackson

11:21 am - 10:48 pmSTL Lambert-St Louis-ROA Roanoke

10h 27m2 stops Minneapolis St Paul New York LaGuardia

$866Delta

Fri, Oct 2 - Sun, Oct 4

10:53 am - 5:01 pmROA Roanoke-STL Lambert-St Louis

7h 08m1 stop Chicago O'Hare Intl

5:36 pm - 10:59 pmSTL Lambert-St Louis-ROA Roanoke

4h 23m1 stop Chicago O'Hare Intl

$868United Airlines

Sun, Oct 4 - Tue, Oct 6

6:13 pm - 11:41 pmROA Roanoke-STL Lambert-St Louis

6h 28m1 stop Charlotte Douglas

10:22 am - 4:42 pmSTL Lambert-St Louis-ROA Roanoke

5h 20m1 stop Charlotte Douglas

$868American Airlines

Sun, Oct 4 - Tue, Oct 6

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American Airlines flights from Roanoke to Missouri

Our best American Airlines deals on Roanoke to Missouri flight tickets

American Airlines

Oct 24

ROA6:40 amRoanoke

7h 25m

1 stop

MCI1:05 pmKansas City

Nov 1

MCI6:03 amKansas City

6h 50m

1 stop

ROA1:53 pmRoanoke

$339

American Airlines

Oct 14

ROA5:07 amRoanoke

4h 30m

1 stop

STL8:37 amLambert-St Louis

Oct 18

STL5:00 amLambert-St Louis

4h 29m

1 stop

ROA10:29 amRoanoke

$369

American Airlines

Oct 15

ROA8:15 amRoanoke

7h 29m

1 stop

SGF2:44 pmSpringfield-Branson

Oct 19

SGF6:22 pmSpringfield-Branson

4h 22m

1 stop

ROA11:44 pmRoanoke

$399

Delta flights from Roanoke to Missouri

Our best Delta deals on Roanoke to Missouri flight tickets

Delta

Jan 17

ROA6:00 amRoanoke

5h 48m

1 stop

STL10:48 amLambert-St Louis

Jan 26

STL9:00 amLambert-St Louis

4h 40m

1 stop

ROA2:40 pmRoanoke

$339

Delta

Oct 14

ROA6:00 amRoanoke

4h 29m

1 stop

MCI9:29 amKansas City

Oct 21

MCI4:23 pmKansas City

7h 04m

1 stop

ROA12:27 amRoanoke

$354

Delta

Oct 14

ROA6:00 amRoanoke

4h 29m

1 stop

MCI9:29 amKansas City

Oct 20

MCI4:23 pmKansas City

7h 04m

1 stop

ROA12:27 amRoanoke

$369

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Thu 11/5

4:52 pm-10:50 pm

1 stop6h 58m

Kansas City

Tue 11/10

9:12 am-4:22 pm

1 stop6h 10m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Sat 10/24

6:40 am-1:05 pm

1 stop7h 25m

Kansas City

Sun 11/1

6:03 am-1:53 pm

1 stop6h 50m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Fri 11/13

6:54 pm-11:55 pm

1 stop6h 01m

Kansas City

Sun 11/15

10:32 am-6:14 pm

1 stop6h 42m

$339

Quickest round-trip

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Tue 12/22

11:30 am-3:05 pm

1 stop4h 35m

Kansas City

Tue 12/29

5:20 am-10:45 am

1 stop4h 25m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Sat 11/7

10:40 am-5:34 pm

1 stop7h 54m

Kansas City

Mon 11/9

5:50 pm-11:44 pm

1 stop4h 54m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Thu 11/5

2:55 pm-7:55 pm

1 stop6h 00m

Kansas City

Sat 11/7

1:09 pm-9:01 pm

1 stop6h 52m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Sat 3/27

6:00 am-9:35 am

1 stop4h 35m

Kansas City

Mon 3/29

5:26 pm-12:23 am

1 stop5h 57m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Sat 10/24

9:21 am-1:05 pm

1 stop4h 44m

Kansas City

Sun 11/1

9:12 am-4:22 pm

1 stop6h 10m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Thu 11/5

10:40 am-5:34 pm

1 stop7h 54m

Kansas City

Sat 11/7

11:33 am-7:07 pm

1 stop6h 34m

$339

RoanokeKansas City

ROA Roanoke - MCI Kansas City

ROAMCI

Roanoke

Sat 10/24

1:03 pm-5:42 pm

1 stop5h 39m

Kansas City

Sun 11/1

6:03 am-1:53 pm

1 stop6h 50m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, February is the cheapest month to fly from Roanoke to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $325. If you aren’t able to travel to Missouri during the month of February, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $338.

Can stopping save me money on Roanoke to Missouri flights?

You could potentially save up to 32% on your flight if you consider stops on a Roanoke to Missouri flight.

Cheap Roanoke to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Missouri

Best Price Found	$263
Fastest flight time	4h 23m
Direct flights	None

The best one-way flight to Missouri from Roanoke in the past 72 hours is $263. The best round-trip flight deal from Roanoke to Missouri found on momondo in the last 72 hours is $339.

The fastest flight from Roanoke to Missouri takes 4h 23m

There are no direct flights from Roanoke to Missouri. There are no popular flight routes from Roanoke to Missouri.

Search flight deals

Frequently asked questions about flying from Roanoke to Missouri

When did momondo last update prices for flights from Roanoke Airport to Missouri?
Prices for flights from Roanoke Airport to Missouri are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to Missouri?
As of October 2026, there are 3 operators available to choose from for flights from Roanoke Airport to Missouri.
How old do you have to be to fly from Roanoke Airport to Missouri?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Roanoke to Missouri

Compare and see reviews for airlines that fly from Roanoke to Missouri with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.0 12,097 reviews	Search American Airlines flights
Delta	PriceFrom $254	Free Cancellation	Rating 7.8 8,608 reviews	Search Delta flights
United Airlines	PriceFrom $269	Free Cancellation	Rating 7.4 10,261 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Missouri?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to Missouri. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to Missouri with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to Missouri flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to Missouri?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Missouri from Roanoke.

I’m not ready to book a flight from Roanoke to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Roanoke to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.