What airlines fly to Missouri?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Missouri from Roanoke according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 3 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Roanoke to Missouri?

United Airlines, Delta, and American Airlines are the most popular carriers operating from Roanoke to Missouri

When did momondo last update prices for flights from Roanoke Airport to Missouri?

Prices for flights from Roanoke Airport to Missouri are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to Missouri?

As of December 2025, there are 3 operators available to choose from for flights from Roanoke Airport to Missouri.

How old do you have to be to fly from Roanoke Airport to Missouri?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$239 Cheap Flights from Roanoke to Missouri in 2025/26

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Find the cheapest flights from Roanoke to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 11:02 am

ROA

STL

6h 02m1 stop

9:59 am - 3:07 pm

STL

ROA

4h 08m1 stop

$239Delta

Sat, Jan 17 - Sat, Jan 24

7:50 pm - 11:55 pm

ROA

MCI

5h 05m1 stop

7:00 am - 2:42 pm

MCI

ROA

6h 42m1 stop

$269Delta

Sat, May 30 - Sat, Jun 6

7:05 am - 12:19 pm

ROA

STL

6h 14m1 stop

5:00 pm - 12:04 am

STL

ROA

6h 04m1 stop

$269Delta

Wed, Mar 18 - Tue, Mar 31

7:08 am - 1:38 pm

ROA

STL

7h 30m1 stop

5:00 am - 10:31 am

STL

ROA

4h 31m1 stop

$309American Airlines

Sat, Dec 27 - Sat, Jan 3

5:38 pm - 11:00 pm

ROA

MCI

6h 22m1 stop

11:40 am - 11:23 pm

MCI

ROA

10h 43m2 stops

$317United Airlines

Fri, May 29 - Sat, Jun 6

7:08 am - 1:38 pm

ROA

STL

7h 30m1 stop

5:00 am - 10:31 am

STL

ROA

4h 31m1 stop

$339American Airlines

Sat, Dec 27 - Sat, Jan 3

5:38 pm - 11:00 pm

ROA

MCI

6h 22m1 stop

10:00 am - 4:56 pm

MCI

ROA

5h 56m1 stop

$339United Airlines

Fri, May 29 - Sat, Jun 6

6:40 am - 12:27 pm

ROA

STL

6h 47m1 stop

8:15 am - 2:16 pm

STL

ROA

5h 01m1 stop

$349United Airlines

Tue, Dec 30 - Sat, Jan 3

7:00 am - 11:31 am

ROA

MCI

5h 31m1 stop

4:22 pm - 10:19 pm

MCI

ROA

4h 57m1 stop

$364American Airlines

Sat, May 30 - Sat, Jun 6

5:25 pm - 11:39 pm

ROA

MCI

7h 14m2 stops

6:33 pm - 11:45 pm

MCI

ROA

4h 12m1 stop

$403American Airlines

Sat, May 30 - Sat, Jun 6

Delta flights from Roanoke to Missouri

Our best Delta deals on Roanoke to Missouri flight tickets

Delta

Jan 17

ROA6:00 amRoanoke

6h 02m

1 stop

STL11:02 amLambert-St Louis

Jan 24

STL9:59 amLambert-St Louis

4h 08m

1 stop

ROA3:07 pmRoanoke

$239

Find similar

Delta

Mar 18

ROA7:05 amRoanoke

6h 14m

1 stop

STL12:19 pmLambert-St Louis

Mar 31

STL5:00 pmLambert-St Louis

6h 04m

1 stop

ROA12:04 amRoanoke

$269

Find similar

Delta

May 30

ROA7:50 pmRoanoke

5h 05m

1 stop

MCI11:55 pmKansas City

Jun 6

MCI5:00 pmKansas City

5h 49m

1 stop

ROA11:49 pmRoanoke

$289

Find similar

American Airlines flights from Roanoke to Missouri

Our best American Airlines deals on Roanoke to Missouri flight tickets

American Airlines

Dec 27

ROA7:08 amRoanoke

7h 30m

1 stop

STL1:38 pmLambert-St Louis

Jan 3

STL5:00 amLambert-St Louis

4h 31m

1 stop

ROA10:31 amRoanoke

$309

Find similar

American Airlines

Dec 27

ROA7:08 amRoanoke

7h 30m

1 stop

STL1:38 pmLambert-St Louis

Jan 3

STL5:00 amLambert-St Louis

4h 31m

1 stop

ROA10:31 amRoanoke

$339

Find similar

American Airlines

May 30

ROA7:00 amRoanoke

5h 31m

1 stop

MCI11:31 amKansas City

Jun 6

MCI4:22 pmKansas City

4h 57m

1 stop

ROA10:19 pmRoanoke

$364

Find similar

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 1/17

6:00 am-11:02 am

1 stop6h 02m

Lambert-St Louis

Sat 1/24

9:59 am-3:07 pm

1 stop4h 08m

$239

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Sat 5/30

7:50 pm-11:55 pm

1 stop5h 05m

Kansas City

Sat 6/6

7:00 am-2:42 pm

1 stop6h 42m

$269

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Wed 3/18

7:05 am-12:19 pm

1 stop6h 14m

Lambert-St Louis

Tue 3/31

5:00 pm-12:04 am

1 stop6h 04m

$269

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 12/27

7:08 am-1:38 pm

1 stop7h 30m

Lambert-St Louis

Sat 1/3

5:00 am-10:31 am

1 stop4h 31m

$309

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Fri 5/29

5:38 pm-11:00 pm

1 stop6h 22m

Kansas City

Sat 6/6

11:40 am-11:23 pm

2 stops10h 43m

$317

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 12/27

7:08 am-1:38 pm

1 stop7h 30m

Lambert-St Louis

Sat 1/3

5:00 am-10:31 am

1 stop4h 31m

$339

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Fri 5/29

5:38 pm-11:00 pm

1 stop6h 22m

Kansas City

Sat 6/6

10:00 am-4:56 pm

1 stop5h 56m

$339

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 12/30

6:40 am-12:27 pm

1 stop6h 47m

Lambert-St Louis

Sat 1/3

8:15 am-2:16 pm

1 stop5h 01m

$349

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Sat 5/30

7:00 am-11:31 am

1 stop5h 31m

Kansas City

Sat 6/6

4:22 pm-10:19 pm

1 stop4h 57m

$364

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Sat 5/30

5:25 pm-11:39 pm

2 stops7h 14m

Kansas City

Sat 6/6

6:33 pm-11:45 pm

1 stop4h 12m

$403

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, August is the cheapest month to fly from Roanoke to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $288. If you aren’t able to travel to Missouri during the month of August, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $308.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Roanoke to Missouri is on a Tuesday when prices can be found for as low as $316. Flights from Roanoke to Missouri on a Monday will generally be more expensive and average around $582. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the evening. momondo users have found flights departing from Roanoke to Missouri in the evening for as low as $269. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $462. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Roanoke to Missouri flights?

You could potentially save up to 53% on your flight if you consider stops on a Roanoke to Missouri flight.

Cheap Roanoke to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Missouri

Fastest flight time	4h 23m
Direct flights	None

The fastest flight from Roanoke to Missouri takes 4h 23m

There are no direct flights from Roanoke to Missouri. There are no popular flight routes from Roanoke to Missouri.

Search flight deals

When did momondo last update prices for flights from Roanoke Airport to Missouri?
Prices for flights from Roanoke Airport to Missouri are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to Missouri?
As of December 2025, there are 3 operators available to choose from for flights from Roanoke Airport to Missouri.
How old do you have to be to fly from Roanoke Airport to Missouri?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The necessary travel and health documents for your Missouri trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Roanoke to Missouri

Compare and see reviews for airlines that fly from Roanoke to Missouri with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $248	Free Cancellation	Rating 7.4 9,092 reviews	Search United Airlines flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,052 reviews	Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Missouri?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to Missouri. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to Missouri with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to Missouri flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to Missouri?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Missouri from Roanoke.

I’m not ready to book a flight from Roanoke to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Roanoke to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.