What is the cheapest airline that flies from Roanoke to Mississippi?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Roanoke to Mississippi

When did momondo last update prices for flights from Roanoke Airport to Mississippi?

Prices for flights from Roanoke Airport to Mississippi are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to Mississippi?

As of March 2026, there are 2 operators available to choose from for flights from Roanoke Airport to Mississippi.

How old do you have to be to fly from Roanoke Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$170 Cheap Flights from Roanoke to Mississippi in 2026

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Find the cheapest flights from Roanoke to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:28 pm - 6:49 pm

ROA

JAN

4h 21m

1 stop

5:02 pm - 12:25 am

JAN

ROA

6h 23m

1 stop

$291Delta

Sat, Apr 18 - Tue, Apr 21

6:00 am - 9:09 am

ROA

JAN

4h 09m

1 stop

5:36 am - 10:28 am

JAN

ROA

3h 52m

1 stop

$310Delta

Sat, Apr 11 - Tue, Apr 14

7:50 pm - 11:15 pm

ROA

JAN

4h 25m

1 stop

5:36 am - 10:28 am

JAN

ROA

3h 52m

1 stop

$315Delta

Wed, Apr 15 - Sat, Apr 18

7:51 pm - 11:24 pm

ROA

JAN

4h 33m

1 stop

5:04 pm - 12:04 am

JAN

ROA

6h 00m

1 stop

$329Delta

Wed, Apr 8 - Sat, Apr 11

6:00 am - 11:02 am

ROA

MEM

6h 02m

1 stop

7:26 pm - 12:25 am

MEM

ROA

3h 59m

1 stop

$329Delta

Sun, Apr 12 - Mon, Apr 20

7:51 pm - 11:24 pm

ROA

MEM

4h 33m

1 stop

7:33 pm - 12:04 am

MEM

ROA

3h 31m

1 stop

$334Delta

Fri, Apr 10 - Sun, Apr 12

6:45 am - 10:54 am

ROA

MEM

5h 09m

1 stop

7:30 am - 1:29 pm

MEM

ROA

4h 59m

1 stop

$339United Airlines

Wed, Apr 1 - Sun, Apr 5

6:45 am - 10:54 am

ROA

MEM

5h 09m

1 stop

7:30 am - 7:10 pm

MEM

ROA

10h 40m

2 stops

$344United Airlines

Wed, Apr 1 - Sun, Apr 5

8:38 pm - 6:23 pm

ROA

MEM

22h 45m

1 stop

8:05 am - 2:19 pm

MEM

ROA

5h 14m

1 stop

$351Multiple Airlines

Thu, May 14 - Mon, May 18

2:54 pm - 6:11 pm

ROA

MEM

4h 17m

1 stop

6:00 am - 2:25 pm

MEM

ROA

7h 25m

1 stop

$364American Airlines

Sat, May 2 - Fri, Aug 21

American Airlines flights from Roanoke to Mississippi

Our best American Airlines deals on Roanoke to Mississippi flight tickets

American Airlines

May 2

ROA2:54 pmRoanoke

4h 17m

1 stop

MEM6:11 pmMemphis

Aug 21

MEM6:00 amMemphis

7h 25m

1 stop

ROA2:25 pmRoanoke

$364

American Airlines

May 2

ROA8:09 amRoanoke

7h 40m

2 stops

MEM2:49 pmMemphis

Aug 21

MEM6:49 pmMemphis

4h 10m

1 stop

ROA11:59 pmRoanoke

$442

American Airlines

Apr 16

ROA8:09 amRoanoke

7h 14m

2 stops

MEM2:23 pmMemphis

Apr 23

MEM5:00 amMemphis

4h 38m

1 stop

ROA10:38 amRoanoke

$488

United Airlines flights from Roanoke to Mississippi

Our best United Airlines deals on Roanoke to Mississippi flight tickets

United Airlines

Apr 1

ROA6:45 amRoanoke

5h 09m

1 stop

MEM10:54 amMemphis

Apr 5

MEM7:30 amMemphis

4h 59m

1 stop

ROA1:29 pmRoanoke

$339

United Airlines

Apr 1

ROA6:45 amRoanoke

5h 09m

1 stop

MEM10:54 amMemphis

Apr 5

MEM7:30 amMemphis

10h 40m

2 stops

ROA7:10 pmRoanoke

$344

United Airlines

Apr 7

ROA2:55 pmRoanoke

9h 41m

2 stops

MEM11:36 pmMemphis

Apr 11

MEM7:30 amMemphis

10h 40m

2 stops

ROA7:10 pmRoanoke

$349

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Sat 4/18

3:28 pm-6:49 pm

1 stop4h 21m

Jackson-Evers Intl

Tue 4/21

5:02 pm-12:25 am

1 stop6h 23m

$291

Quickest round-trip

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Sat 4/11

6:00 am-9:09 am

1 stop4h 09m

Jackson-Evers Intl

Tue 4/14

5:36 am-10:28 am

1 stop3h 52m

$310

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Wed 4/15

7:50 pm-11:15 pm

1 stop4h 25m

Jackson-Evers Intl

Sat 4/18

5:36 am-10:28 am

1 stop3h 52m

$315

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Wed 4/8

7:51 pm-11:24 pm

1 stop4h 33m

Jackson-Evers Intl

Sat 4/11

5:04 pm-12:04 am

1 stop6h 00m

$329

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Sun 4/12

6:00 am-11:02 am

1 stop6h 02m

Memphis

Mon 4/20

7:26 pm-12:25 am

1 stop3h 59m

$329

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Fri 4/10

7:51 pm-11:24 pm

1 stop4h 33m

Memphis

Sun 4/12

7:33 pm-12:04 am

1 stop3h 31m

$334

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Wed 4/1

6:45 am-10:54 am

1 stop5h 09m

Memphis

Sun 4/5

7:30 am-1:29 pm

1 stop4h 59m

$339

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Wed 4/1

6:45 am-10:54 am

1 stop5h 09m

Memphis

Sun 4/5

7:30 am-7:10 pm

2 stops10h 40m

$344

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Thu 5/14

8:38 pm-6:23 pm

1 stop22h 45m

Memphis

Mon 5/18

8:05 am-2:19 pm

1 stop5h 14m

$351

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Sat 5/2

2:54 pm-6:11 pm

1 stop4h 17m

Memphis

Fri 8/21

6:00 am-2:25 pm

1 stop7h 25m

$364

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Roanoke to Mississippi flights?

You could potentially save up to 66% on your flight if you consider stops on a Roanoke to Mississippi flight.

Cheap Roanoke to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Mississippi

Fastest flight time	4h 16m
Direct flights	None

The fastest flight from Roanoke to Mississippi takes 4h 16m

There are no direct flights from Roanoke to Mississippi. There are no popular flight routes from Roanoke to Mississippi.

Search flight deals

When did momondo last update prices for flights from Roanoke Airport to Mississippi?
Prices for flights from Roanoke Airport to Mississippi are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to Mississippi?
As of March 2026, there are 2 operators available to choose from for flights from Roanoke Airport to Mississippi.
How old do you have to be to fly from Roanoke Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Roanoke to Mississippi

Compare and see reviews for airlines that fly from Roanoke to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,489 reviews		Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,319 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Mississippi?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Mississippi for you.

Can I find flights from Roanoke to Mississippi with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Mississippi from Roanoke with this policy.

How can momondo help me find flights from Roanoke to Mississippi?

momondo provides multiple filters to help you find the best flight to Mississippi from Roanoke. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Roanoke to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Roanoke to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.