What is the cheapest airline that flies from Roanoke to Mississippi?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Roanoke to Mississippi

When did momondo last update prices for flights from Roanoke Airport to Mississippi?

Prices for flights from Roanoke Airport to Mississippi are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to Mississippi?

As of May 2026, there are 2 operators available to choose from for flights from Roanoke Airport to Mississippi.

How old do you have to be to fly from Roanoke Airport to Mississippi?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$300 Cheap Flights from Roanoke to Mississippi in 2026

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Find the cheapest flights from Roanoke to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:30 pm - 6:52 pm

ROA

JAN

4h 22m

1 stop

7:23 pm - 12:34 am

JAN

ROA

4h 11m

1 stop

$309Delta

Wed, May 27 - Sun, May 31

7:58 pm - 11:25 pm

ROA

MEM

4h 27m

1 stop

2:56 pm - 9:20 pm

MEM

ROA

5h 24m

1 stop

$309American Airlines

Sat, Jun 6 - Wed, Jun 10

6:00 am - 8:50 am

ROA

MEM

3h 50m

1 stop

5:15 am - 10:33 am

MEM

ROA

4h 18m

1 stop

$319Delta

Sat, Jun 6 - Wed, Jun 10

6:00 am - 8:54 am

ROA

JAN

3h 54m

1 stop

5:30 am - 10:33 am

JAN

ROA

4h 03m

1 stop

$324Delta

Wed, Jun 3 - Sun, Jun 7

12:58 pm - 8:05 pm

ROA

MEM

8h 07m

1 stop

5:00 am - 10:45 am

MEM

ROA

4h 45m

1 stop

$339American Airlines

Wed, May 20 - Sun, May 24

6:00 am - 8:54 am

ROA

JAN

3h 54m

1 stop

5:30 am - 10:33 am

JAN

ROA

4h 03m

1 stop

$339Delta

Thu, Jun 4 - Sun, Jun 7

8:09 am - 2:18 pm

ROA

MEM

7h 09m

2 stops

5:00 am - 10:45 am

MEM

ROA

4h 45m

1 stop

$344American Airlines

Wed, May 20 - Sun, May 24

5:47 pm - 11:46 pm

ROA

MEM

6h 59m

1 stop

5:45 am - 1:35 pm

MEM

ROA

6h 50m

1 stop

$389United Airlines

Sat, Aug 29 - Tue, Sep 1

10:50 am - 2:43 pm

ROA

MEM

4h 53m

1 stop

7:15 am - 7:07 pm

MEM

ROA

10h 52m

2 stops

$394United Airlines

Sat, Aug 29 - Tue, Sep 1

6:15 am - 2:43 pm

ROA

MEM

9h 28m

2 stops

7:15 am - 7:07 pm

MEM

ROA

10h 52m

2 stops

$399United Airlines

Sat, Aug 29 - Tue, Sep 1

United Airlines flights from Roanoke to Mississippi

Our best United Airlines deals on Roanoke to Mississippi flight tickets

United Airlines

Aug 29

ROA5:47 pmRoanoke

6h 59m

1 stop

MEM11:46 pmMemphis

Sep 1

MEM5:45 amMemphis

6h 50m

1 stop

ROA1:35 pmRoanoke

$389

United Airlines

Aug 29

ROA10:50 amRoanoke

4h 53m

1 stop

MEM2:43 pmMemphis

Sep 1

MEM7:15 amMemphis

10h 52m

2 stops

ROA7:07 pmRoanoke

$394

United Airlines

Aug 29

ROA6:15 amRoanoke

9h 28m

2 stops

MEM2:43 pmMemphis

Sep 1

MEM7:15 amMemphis

10h 52m

2 stops

ROA7:07 pmRoanoke

$399

American Airlines flights from Roanoke to Mississippi

Our best American Airlines deals on Roanoke to Mississippi flight tickets

American Airlines

Jun 6

ROA7:58 pmRoanoke

4h 27m

1 stop

MEM11:25 pmMemphis

Jun 10

MEM2:56 pmMemphis

5h 24m

1 stop

ROA9:20 pmRoanoke

$309

American Airlines

May 20

ROA12:58 pmRoanoke

8h 07m

1 stop

MEM8:05 pmMemphis

May 24

MEM5:00 amMemphis

4h 45m

1 stop

ROA10:45 amRoanoke

$339

American Airlines

May 20

ROA8:09 amRoanoke

7h 09m

2 stops

MEM2:18 pmMemphis

May 24

MEM5:00 amMemphis

4h 45m

1 stop

ROA10:45 amRoanoke

$344

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Wed 5/27

3:30 pm-6:52 pm

1 stop4h 22m

Jackson-Evers Intl

Sun 5/31

7:23 pm-12:34 am

1 stop4h 11m

$309

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Sat 6/6

7:58 pm-11:25 pm

1 stop4h 27m

Memphis

Wed 6/10

2:56 pm-9:20 pm

1 stop5h 24m

$309

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Sat 6/6

6:00 am-8:50 am

1 stop3h 50m

Memphis

Wed 6/10

5:15 am-10:33 am

1 stop4h 18m

$319

Quickest round-trip

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Wed 6/3

6:00 am-8:54 am

1 stop3h 54m

Jackson-Evers Intl

Sun 6/7

5:30 am-10:33 am

1 stop4h 03m

$324

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Wed 5/20

12:58 pm-8:05 pm

1 stop8h 07m

Memphis

Sun 5/24

5:00 am-10:45 am

1 stop4h 45m

$339

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Thu 6/4

6:00 am-8:54 am

1 stop3h 54m

Jackson-Evers Intl

Sun 6/7

5:30 am-10:33 am

1 stop4h 03m

$339

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Wed 5/20

8:09 am-2:18 pm

2 stops7h 09m

Memphis

Sun 5/24

5:00 am-10:45 am

1 stop4h 45m

$344

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Sat 8/29

5:47 pm-11:46 pm

1 stop6h 59m

Memphis

Tue 9/1

5:45 am-1:35 pm

1 stop6h 50m

$389

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Sat 8/29

10:50 am-2:43 pm

1 stop4h 53m

Memphis

Tue 9/1

7:15 am-7:07 pm

2 stops10h 52m

$394

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Sat 8/29

6:15 am-2:43 pm

2 stops9h 28m

Memphis

Tue 9/1

7:15 am-7:07 pm

2 stops10h 52m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Roanoke to Mississippi flights?

You could potentially save up to 66% on your flight if you consider stops on a Roanoke to Mississippi flight.

Cheap Roanoke to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Mississippi

Fastest flight time	4h 27m
Direct flights	None

The fastest flight from Roanoke to Mississippi takes 4h 27m

There are no direct flights from Roanoke to Mississippi. There are no popular flight routes from Roanoke to Mississippi.

Search flight deals

Frequently asked questions about flying from Roanoke to Mississippi

When did momondo last update prices for flights from Roanoke Airport to Mississippi?
Prices for flights from Roanoke Airport to Mississippi are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to Mississippi?
As of May 2026, there are 2 operators available to choose from for flights from Roanoke Airport to Mississippi.
How old do you have to be to fly from Roanoke Airport to Mississippi?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The necessary travel and health documents for your Mississippi trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Roanoke to Mississippi

Compare and see reviews for airlines that fly from Roanoke to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,669 reviews		Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,457 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Mississippi?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Roanoke to Mississippi for you.

Can I find flights from Roanoke to Mississippi with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Mississippi from Roanoke with this policy.

How can momondo help me find flights from Roanoke to Mississippi?

momondo provides multiple filters to help you find the best flight to Mississippi from Roanoke. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Roanoke to Mississippi right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Roanoke to Mississippi now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mississippi and let you know when they change.