Cheap flights from Roanoke to Chicago from $226

The month of January is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Roanoke averaging around $319.

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Friday when prices can be found for as low as $415. This is often the case because there is less demand to fly during this day of the week. On the other hand, Monday is the most expensive day to depart from Roanoke because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $633.

Flying to Chicago O'Hare Intl Airport from Roanoke in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $423 when looking at flights departing in the afternoon. Try not to purchase tickets at noon because they tend to be around $491. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Roanoke to Chicago O'Hare Intl for the best Roanoke - Chicago O'Hare Intl flight prices

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $353 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Roanoke for as low as $294 on momondo.

There are 4 cabin classes available to choose from on Roanoke to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Roanoke to Chicago O'Hare Intl Airport.

As of September 2026, prices for Roanoke to Chicago O'Hare Intl Airport flights are approximately 49% more expensive when compared to flights at the same time last year.

As of September 2026, there are 10 flights per day flying from Roanoke to Chicago O'Hare Intl Airport. The most common time of day flights depart is 5:00PM, with 60% of flights taking off at noon.

The number of flights available between Roanoke and Chicago O'Hare Intl Airport is 70 per week as of September 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.