Cheap flights from Raleigh to St. Louis from $62

In general, January is the cheapest month to fly from Raleigh to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $351. The month of October is another great option to travel to St. Louis, with average flight prices from Raleigh averaging around $355.

The cheapest day to depart on your flight to St. Louis is on a Saturday when prices can be found for as low as $394. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $536. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Raleigh in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $446 when looking at flights departing in the afternoon. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $618 per ticket.

Fly from Raleigh-Durham to Lambert-St Louis for the best Raleigh-Durham - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $408 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Raleigh for as low as $196 on momondo.

There is only 1 cabin class available to choose from on Raleigh to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 43% on your flight if you consider stops on a Raleigh to St. Louis flight.

As of August 2026, prices for Raleigh to St. Louis flights are approximately 30% more expensive when compared to flights at the same time last year.

Delta and United Airlines are the most popular carriers operating from Raleigh-Durham to Lambert-St Louis

Southwest, Delta and American Airlines are the top three most popular airlines that fly to St. Louis from Raleigh according to our data. Southwest is the first choice among our users, with 46% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 5 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

Atlanta (ATL) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Flights via Atlanta (ATL) offer the lowest average round-trip price of $194.

Flights connecting via Nashville (BNA) have the shortest average one-way travel time: 6h 30m.

Nashville (BNA) has the shortest average layover time for this route: 2h 25m.