What airlines fly to South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to South Carolina from Portland according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Portland to South Carolina?

Delta, American Airlines, and United Airlines are the most popular carriers operating from Portland to South Carolina

How many flights depart from Portland to South Carolina on average per week?

As of April 2026, 6 flights take off from Portland and land in South Carolina each week. The most common flight departure day for this route is Mon, with 17% of weekly flights taking off on this day.

When did momondo last update prices for flights from Portland Airport to South Carolina?

Prices for flights from Portland Airport to South Carolina were last updated today.

How many operators does momondo search for flights from Portland Airport to South Carolina?

As of April 2026, there are 6 operators available to choose from for flights from Portland Airport to South Carolina.

How old do you have to be to fly from Portland Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$112 Cheap Flights from Portland to South Carolina in 2026

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Find the cheapest flights from Portland to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:20 am - 11:00 pm

PDX

CHS

8h 40m

1 stop

7:19 pm - 12:50 am

CHS

PDX

8h 31m

1 stop

$265American Airlines

Wed, Jun 3 - Tue, Jun 9

10:40 pm - 10:48 am

PDX

GSP

9h 08m

1 stop

5:25 pm - 12:50 am

GSP

PDX

10h 25m

1 stop

$269American Airlines

Tue, Jun 2 - Wed, Jun 3

9:39 pm - 9:04 am

PDX

GSP

8h 25m

1 stop

1:09 pm - 10:02 pm

GSP

PDX

11h 53m

2 stops

$274Delta

Tue, Jun 2 - Wed, Jun 3

2:06 pm - 11:59 pm

PDX

CHS

6h 53m

1 stop

6:00 am - 11:46 am

CHS

PDX

8h 46m

1 stop

$275Delta

Tue, Jun 2 - Sat, Jun 6

11:30 pm - 12:25 pm

PDX

GSP

9h 55m

2 stops

7:00 am - 3:00 pm

GSP

PDX

11h 00m

2 stops

$281Southwest

Tue, Sep 15 - Tue, Sep 22

11:30 pm - 10:16 am

PDX

CHS

7h 46m

1 stop

10:00 am - 6:47 pm

CHS

PDX

11h 47m

2 stops

$310United Airlines

Wed, Jun 3 - Tue, Jun 9

11:30 pm - 10:52 am

PDX

SAV

8h 22m

1 stop

12:10 pm - 8:19 pm

SAV

PDX

11h 09m

1 stop

$311United Airlines

Tue, May 26 - Tue, Jun 9

10:45 pm - 10:10 am

PDX

SAV

8h 25m

1 stop

10:50 am - 5:45 pm

SAV

PDX

9h 55m

2 stops

$318Southwest

Tue, Sep 8 - Tue, Sep 15

9:22 am - 8:36 pm

PDX

MYR

32h 14m

2 stops

9:59 pm - 1:48 pm

MYR

PDX

18h 49m

1 stop

$329Multiple Airlines

Fri, May 29 - Sat, Jun 6

2:44 pm - 3:18 pm

PDX

MYR

21h 34m

1 stop

6:18 pm - 4:46 pm

MYR

PDX

49h 28m

2 stops

$402Multiple Airlines

Thu, May 21 - Thu, May 28

Frontier flights from Portland to South Carolina

Our best Frontier deals on Portland to South Carolina flight tickets

Frontier

May 22

PDX12:35 pmPortland

24h 25m

2 stops

CLT4:00 pmCharlotte Douglas

May 27

CLT8:55 amCharlotte Douglas

28h 10m

1 stop

PDX10:05 amPortland

$466

Frontier

May 21

PDX11:15 amPortland

16h 44m

1 stop

CLT6:59 amCharlotte Douglas

May 24

CLT7:14 pmCharlotte Douglas

24h 32m

1 stop

PDX4:46 pmPortland

$474

Frontier

Jun 15

PDX12:26 pmPortland

26h 53m

1 stop

CLT6:19 pmCharlotte Douglas

Jun 20

CLT10:14 pmCharlotte Douglas

21h 43m

1 stop

PDX4:57 pmPortland

$476

American Airlines flights from Portland to South Carolina

Our best American Airlines deals on Portland to South Carolina flight tickets

American Airlines

Jun 3

PDX11:20 amPortland

8h 40m

1 stop

CHS11:00 pmCharleston

Jun 9

CHS7:19 pmCharleston

8h 31m

1 stop

PDX12:50 amPortland

$265

American Airlines

Jun 2

PDX10:40 pmPortland

9h 08m

1 stop

GSP10:48 amGreenville

Jun 3

GSP5:25 pmGreenville

10h 25m

1 stop

PDX12:50 amPortland

$269

American Airlines

Jun 2

PDX5:07 amPortland

8h 28m

1 stop

GSP4:35 pmGreenville

Jun 3

GSP7:54 pmGreenville

7h 56m

1 stop

PDX12:50 amPortland

$285

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Wed 6/3

11:20 am-11:00 pm

1 stop8h 40m

Charleston

Tue 6/9

7:19 pm-12:50 am

1 stop8h 31m

$265

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 6/2

10:40 pm-10:48 am

1 stop9h 08m

Greenville

Wed 6/3

5:25 pm-12:50 am

1 stop10h 25m

$269

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 6/2

9:39 pm-9:04 am

1 stop8h 25m

Greenville

Wed 6/3

1:09 pm-10:02 pm

2 stops11h 53m

$274

Quickest round-trip

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Tue 6/2

2:06 pm-11:59 pm

1 stop6h 53m

Charleston

Sat 6/6

6:00 am-11:46 am

1 stop8h 46m

$275

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 9/15

11:30 pm-12:25 pm

2 stops9h 55m

Greenville

Tue 9/22

7:00 am-3:00 pm

2 stops11h 00m

$281

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Wed 6/3

11:30 pm-10:16 am

1 stop7h 46m

Charleston

Tue 6/9

10:00 am-6:47 pm

2 stops11h 47m

$310

PortlandSavannah

PDX - SAV

PDXSAV

Portland

Tue 5/26

11:30 pm-10:52 am

1 stop8h 22m

Savannah/Hilton Head

Tue 6/9

12:10 pm-8:19 pm

1 stop11h 09m

$311

PortlandSavannah

PDX - SAV

PDXSAV

Portland

Tue 9/8

10:45 pm-10:10 am

1 stop8h 25m

Savannah/Hilton Head

Tue 9/15

10:50 am-5:45 pm

2 stops9h 55m

$318

PortlandMyrtle Beach

PDX - MYR

PDXMYR

Portland

Fri 5/29

9:22 am-8:36 pm

2 stops32h 14m

Myrtle Beach Intl

Sat 6/6

9:59 pm-1:48 pm

1 stop18h 49m

$329

PortlandMyrtle Beach

PDX - MYR

PDXMYR

Portland

Thu 5/21

2:44 pm-3:18 pm

1 stop21h 34m

Myrtle Beach Intl

Thu 5/28

6:18 pm-4:46 pm

2 stops49h 28m

$402

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Portland is in January. Flight prices, which tend to average around $346, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Portland during September instead. Flights to South Carolina in September, while not as cheap as those in January, still average around $369.

How far in advance should I book a flight from Portland to South Carolina?

You are more likely to see cheaper flights to South Carolina from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $455 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Portland for as low as $330 on momondo.

Can stopping save me money on Portland to South Carolina flights?

You could potentially save up to 4% on your flight if you consider stops on a Portland to South Carolina flight.

Cheap Portland to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to South Carolina

Fastest flight time	4h 52m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Portland to South Carolina takes 4h 52m

Direct flights go from Portland to South Carolina every day.

There are 57 airports in South Carolina. From Portland there are direct flights to Charlotte Douglas (CLT).

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Frequently asked questions about flying from Portland to South Carolina

When did momondo last update prices for flights from Portland Airport to South Carolina?
Prices for flights from Portland Airport to South Carolina were last updated today.
How many operators does momondo search for flights from Portland Airport to South Carolina?
As of April 2026, there are 6 operators available to choose from for flights from Portland Airport to South Carolina.
How old do you have to be to fly from Portland Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Portland to South Carolina

Compare and see reviews for airlines that fly from Portland to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $228	Free Cancellation	Rating 7.9 8,450 reviews	Search Delta flights
United Airlines	PriceFrom $276	Free Cancellation	Rating 7.4 9,643 reviews	Search United Airlines flights
Alaska Airlines	PriceFrom $298	Free Cancellation	Rating 7.9 12,280 reviews	Search Alaska Airlines flights
American Airlines	PriceFrom $304	Free Cancellation	Rating 7.1 11,666 reviews	Search American Airlines flights
Southwest	PriceFrom $329	Free Cancellation	Rating 8.0 4,333 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Portland.

Can I find flights from Portland to South Carolina with flexible booking policies on momondo?

momondo does allow users to show only those flights to South Carolina from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Portland.

I’m not ready to book a flight from Portland to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Portland and alert you when they change.