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Cheap flights from Portland to South Carolina from $106

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to South Carolina departing on 1/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Portland to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:59 am - 6:42 pm
PDX
-
CLT
27h 43m1 stop
Multiple Airlines Logo
2:46 pm - 6:06 pm
CLT
-
PDX
30h 20m2 stops
$265Multiple Airlines
Thu, Jan 15 - Wed, Feb 25
Frontier Logo
11:59 am - 6:42 pm
PDX
-
CLT
27h 43m1 stop
Frontier Logo
4:14 pm - 6:43 pm
CLT
-
PDX
29h 29m2 stops
$267Frontier
Thu, Jan 15 - Thu, Feb 26
United Airlines Logo
7:00 am - 8:02 pm
PDX
-
CHS
10h 02m1 stop
United Airlines Logo
4:01 pm - 9:12 pm
CHS
-
PDX
8h 11m1 stop
$275United Airlines
Wed, Jan 28 - Sat, Jan 31
American Airlines Logo
10:15 pm - 9:48 am
PDX
-
CHS
8h 33m1 stop
American Airlines Logo
7:32 am - 1:21 pm
CHS
-
PDX
8h 49m1 stop
$276American Airlines
Tue, Jan 13 - Sun, Jan 18
United Airlines Logo
7:00 am - 8:02 pm
PDX
-
CHS
10h 02m1 stop
United Airlines Logo
10:30 am - 9:12 pm
CHS
-
PDX
13h 42m2 stops
$280United Airlines
Wed, Jan 28 - Sat, Jan 31
Delta Logo
6:50 am - 4:53 pm
PDX
-
GSP
7h 03m1 stop
Delta Logo
5:40 am - 10:47 am
GSP
-
PDX
8h 07m1 stop
$307Delta
Sat, Jan 17 - Tue, Jan 20
Delta Logo
5:00 pm - 9:19 am
PDX
-
GSP
13h 19m2 stops
Delta Logo
3:05 pm - 7:13 pm
GSP
-
PDX
7h 08m1 stop
$312Delta
Sat, Jan 17 - Tue, Jan 20
American Airlines Logo
11:59 pm - 1:39 pm
PDX
-
CHS
10h 40m2 stops
American Airlines Logo
10:18 am - 7:51 pm
CHS
-
PDX
12h 33m2 stops
$315American Airlines
Sun, Jan 11 - Wed, Jan 14
Southwest Logo
6:30 am - 4:50 pm
PDX
-
SAV
7h 20m1 stop
Southwest Logo
7:45 am - 3:40 pm
SAV
-
PDX
10h 55m2 stops
$345Southwest
Wed, Feb 18 - Wed, Feb 25
Southwest Logo
6:30 am - 7:10 pm
PDX
-
SAV
9h 40m2 stops
Southwest Logo
4:00 pm - 10:15 pm
SAV
-
PDX
9h 15m2 stops
$350Southwest
Wed, Feb 18 - Wed, Feb 25

Frontier flights from Portland to South Carolina

Our best Frontier deals on Portland to South Carolina flight tickets
Frontier
Jan 15
PDX11:59 amPortland
27h 43m
1 stop
CLT6:42 pmCharlotte Douglas
Feb 26
CLT4:14 pmCharlotte Douglas
29h 29m
2 stops
PDX6:43 pmPortland
$267
Find similar
Frontier
Jan 4
PDX12:47 pmPortland
25h 46m
2 stops
CLT5:33 pmCharlotte Douglas
Jan 15
CLT6:43 pmCharlotte Douglas
19h 21m
1 stop
PDX11:04 amPortland
$274
Find similar
Frontier
Jan 4
PDX12:47 pmPortland
19h 35m
1 stop
CLT11:22 amCharlotte Douglas
Jan 15
CLT6:43 pmCharlotte Douglas
19h 21m
1 stop
PDX11:04 amPortland
$281
Find similar

Southwest flights from Portland to South Carolina

Our best Southwest deals on Portland to South Carolina flight tickets
Southwest
Feb 18
PDX6:30 amPortland
7h 20m
1 stop
SAV4:50 pmSavannah/Hilton Head
Feb 25
SAV7:45 amSavannah/Hilton Head
10h 55m
2 stops
PDX3:40 pmPortland
$345
Find similar
Southwest
Feb 18
PDX6:30 amPortland
9h 40m
2 stops
SAV7:10 pmSavannah/Hilton Head
Feb 25
SAV4:00 pmSavannah/Hilton Head
9h 15m
2 stops
PDX10:15 pmPortland
$350
Find similar
Southwest
Feb 18
PDX6:20 amPortland
9h 50m
2 stops
SAV7:10 pmSavannah/Hilton Head
Feb 21
SAV10:50 amSavannah/Hilton Head
11h 15m
2 stops
PDX7:05 pmPortland
$352
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Portland to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandCharlotte

PDX - CLT

PDXCLT

Portland

Thu 1/15

11:59 am-6:42 pm

1 stop27h 43m

Charlotte Douglas

Wed 2/25

2:46 pm-6:06 pm

2 stops30h 20m

$265

PortlandCharlotte

PDX - CLT

PDXCLT

Portland

Thu 1/15

11:59 am-6:42 pm

1 stop27h 43m

Charlotte Douglas

Thu 2/26

4:14 pm-6:43 pm

2 stops29h 29m

$267

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Wed 1/28

7:00 am-8:02 pm

1 stop10h 02m

Charleston

Sat 1/31

4:01 pm-9:12 pm

1 stop8h 11m

$275

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Tue 1/13

10:15 pm-9:48 am

1 stop8h 33m

Charleston

Sun 1/18

7:32 am-1:21 pm

1 stop8h 49m

$276

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Wed 1/28

7:00 am-8:02 pm

1 stop10h 02m

Charleston

Sat 1/31

10:30 am-9:12 pm

2 stops13h 42m

$280

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 1/17

6:50 am-4:53 pm

1 stop7h 03m

Greenville

Tue 1/20

5:40 am-10:47 am

1 stop8h 07m

$307

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 1/17

5:00 pm-9:19 am

2 stops13h 19m

Greenville

Tue 1/20

3:05 pm-7:13 pm

1 stop7h 08m

$312

PortlandCharleston

PDX - CHS

PDXCHS

Portland

Sun 1/11

11:59 pm-1:39 pm

2 stops10h 40m

Charleston

Wed 1/14

10:18 am-7:51 pm

2 stops12h 33m

$315

PortlandSavannah

PDX - SAV

PDXSAV

Portland

Wed 2/18

6:30 am-4:50 pm

1 stop7h 20m

Savannah/Hilton Head

Wed 2/25

7:45 am-3:40 pm

2 stops10h 55m

$345

PortlandSavannah

PDX - SAV

PDXSAV

Portland

Wed 2/18

6:30 am-7:10 pm

2 stops9h 40m

Savannah/Hilton Head

Wed 2/25

4:00 pm-10:15 pm

2 stops9h 15m

$350

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Portland to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Portland is in January. Flight prices, which tend to average around $281, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Portland during September instead. Flights to South Carolina in September, while not as cheap as those in January, still average around $340.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $417. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $586.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Portland to South Carolina flights are usually those with departure times in the afternoon. Our users have found flights to South Carolina in the afternoon for as low as $277. Try not to purchase tickets in the evening because they tend to be around $547. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $427 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Portland for as low as $274 on momondo.

Can stopping save me money on Portland to South Carolina flights?

You could potentially save up to 15% on your flight if you consider stops on a Portland to South Carolina flight.

Cheap Portland to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to South Carolina

Fastest flight time

4h 44m

Direct flights

Every day

Airports in South Carolina

57 airports
The fastest flight from Portland to South Carolina takes 4h 44m
Direct flights go from Portland to South Carolina every day.
There are 57 airports in South Carolina. From Portland there are direct flights to Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from Portland Airport to South Carolina?

    Prices for flights from Portland Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Portland Airport to South Carolina?

  • How old do you have to be to fly from Portland Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Portland to South Carolina

Compare and see reviews for airlines that fly from Portland to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
8,008 reviews
Search Delta flights
Alaska AirlinesPriceFrom $273Free CancellationRating
8.0
11,469 reviews
Search Alaska Airlines flights
United AirlinesPriceFrom $276Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
American AirlinesPriceFrom $284Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights
SouthwestPriceFrom $366Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Portland.

Can I find flights from Portland to South Carolina with flexible booking policies on momondo?

momondo does allow users to show only those flights to South Carolina from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Portland.

I’m not ready to book a flight from Portland to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Portland and alert you when they change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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