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Cheap flights from Portland to Greenville from $210

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Greenville departing on 10/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Greenville

Cheap round-trip flights

American Airlines Logo
5:51 am - 5:33 pmPDX-GSP
8h 42m1 stop
American Airlines Logo
4:53 pm - 11:45 pmGSP-PDX
9h 52m1 stop
$313American Airlines
Find Deal
Sat, Feb 14 - Tue, Feb 17
Delta Logo
9:45 pm - 9:27 amPDX-GSP
8h 42m1 stop
Delta Logo
5:05 pm - 10:39 pmGSP-PDX
8h 34m1 stop
$334Delta
Find Deal
Tue, Mar 3 - Wed, Mar 4
Delta Logo
11:15 pm - 11:02 amPDX-GSP
8h 47m1 stop
Delta Logo
5:45 am - 11:05 amGSP-PDX
8h 20m1 stop
$337Delta
Find Deal
Wed, Nov 12 - Tue, Feb 24
Delta Logo
10:20 am - 11:34 pmPDX-GSP
10h 14m2 stops
Delta Logo
6:00 am - 10:16 amGSP-PDX
7h 16m1 stop
$339Delta
Find Deal
Wed, Oct 1 - Sat, Oct 11
Delta Logo
11:15 pm - 11:02 amPDX-GSP
8h 47m1 stop
Delta Logo
12:00 pm - 8:44 pmGSP-PDX
11h 44m2 stops
$342Delta
Find Deal
Wed, Nov 12 - Tue, Feb 24
Delta Logo
6:04 am - 10:05 pmPDX-GSP
13h 01m2 stops
Delta Logo
7:15 am - 4:51 pmGSP-PDX
12h 36m2 stops
$344Delta
Find Deal
Sat, Feb 14 - Tue, Feb 17
Delta Logo
5:05 pm - 9:02 amPDX-GSP
12h 57m2 stops
Delta Logo
12:00 pm - 8:44 pmGSP-PDX
11h 44m2 stops
$347Delta
Find Deal
Tue, Nov 18 - Tue, Feb 24
United Airlines Logo
7:00 am - 4:53 pmPDX-GSP
6h 53m1 stop
United Airlines Logo
6:30 am - 11:35 amGSP-PDX
8h 05m1 stop
$359United Airlines
Find Deal
Sat, Nov 15 - Sat, Feb 21
American Airlines Logo
11:59 pm - 12:08 pmPDX-GSP
9h 09m2 stops
American Airlines Logo
4:53 pm - 11:45 pmGSP-PDX
9h 52m1 stop
$423American Airlines
Find Deal
Sat, Feb 14 - Tue, Feb 17
American Airlines Logo
11:44 am - 10:30 pmPDX-GSP
7h 46m1 stop
American Airlines Logo
6:09 pm - 11:29 pmGSP-PDX
8h 20m1 stop
$442American Airlines
Find Deal
Mon, Sep 29 - Tue, Oct 7

United Airlines flights from Portland to Greenville

Our best United Airlines deals on Portland to Greenville flight tickets
United Airlines
Nov 15
PDX7:00 amPortland
6h 53m
1 stop
GSP4:53 pmGreenville
Feb 21
GSP6:30 amGreenville
8h 05m
1 stop
PDX11:35 amPortland
$359
Find similar
United Airlines
Sep 29
PDX7:30 amPortland
12h 09m
2 stops
GSP10:39 pmGreenville
Oct 3
GSP5:00 pmGreenville
8h 27m
1 stop
PDX10:27 pmPortland
$552
Find similar
United Airlines
Sep 18
PDX8:15 amPortland
7h 37m
1 stop
GSP6:52 pmGreenville
Sep 22
GSP4:30 pmGreenville
19h 58m
1 stop
PDX9:28 amPortland
$936
Find similar

Delta flights from Portland to Greenville

Our best Delta deals on Portland to Greenville flight tickets
Delta
Mar 3
PDX9:45 pmPortland
8h 42m
1 stop
GSP9:27 amGreenville
Mar 4
GSP5:05 pmGreenville
8h 34m
1 stop
PDX10:39 pmPortland
$334
Find similar
Delta
Nov 12
PDX11:15 pmPortland
8h 47m
1 stop
GSP11:02 amGreenville
Feb 24
GSP5:45 amGreenville
8h 20m
1 stop
PDX11:05 amPortland
$337
Find similar
Delta
Oct 1
PDX10:20 amPortland
10h 14m
2 stops
GSP11:34 pmGreenville
Oct 11
GSP6:00 amGreenville
7h 16m
1 stop
PDX10:16 amPortland
$339
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Portland to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 2/14

5:51 am-5:33 pm

1 stop8h 42m

Greenville

Tue 2/17

4:53 pm-11:45 pm

1 stop9h 52m

$313

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 3/3

9:45 pm-9:27 am

1 stop8h 42m

Greenville

Wed 3/4

5:05 pm-10:39 pm

1 stop8h 34m

$334

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Wed 11/12

11:15 pm-11:02 am

1 stop8h 47m

Greenville

Tue 2/24

5:45 am-11:05 am

1 stop8h 20m

$337

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Wed 10/1

10:20 am-11:34 pm

2 stops10h 14m

Greenville

Sat 10/11

6:00 am-10:16 am

1 stop7h 16m

$339

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Wed 11/12

11:15 pm-11:02 am

1 stop8h 47m

Greenville

Tue 2/24

12:00 pm-8:44 pm

2 stops11h 44m

$342

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 2/14

6:04 am-10:05 pm

2 stops13h 01m

Greenville

Tue 2/17

7:15 am-4:51 pm

2 stops12h 36m

$344

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 11/18

5:05 pm-9:02 am

2 stops12h 57m

Greenville

Tue 2/24

12:00 pm-8:44 pm

2 stops11h 44m

$347

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 11/15

7:00 am-4:53 pm

1 stop6h 53m

Greenville

Sat 2/21

6:30 am-11:35 am

1 stop8h 05m

$359

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 2/14

11:59 pm-12:08 pm

2 stops9h 09m

Greenville

Tue 2/17

4:53 pm-11:45 pm

1 stop9h 52m

$423

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Mon 9/29

11:44 am-10:30 pm

1 stop7h 46m

Greenville

Tue 10/7

6:09 pm-11:29 pm

1 stop8h 20m

$442

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Portland to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Portland averaging around $437.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Portland. The lowest ticket price found for a Wednesday departure recently was $486. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $561. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is at noon. Flights from Portland to Greenville during this time can be as low as $507. Flights to Greenville are more costly in the afternoon, with an average ticket price of $662. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $518 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Portland for as low as $268 on momondo.

How have Portland to Greenville flight prices changed over time?

As of September 2025, prices for Portland to Greenville flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from Portland to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Greenville (PDX to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Greenville

Direct flights

None
There are no direct flights from Portland to Greenville. There are no popular flight routes from Portland to Greenville.
Search flight deals

  • How far is Portland to Greenville by plane?

    A flight from Portland to Greenville will travel around 2221.9 mi. In terms of flight time, this usually takes a little over 6h 44m.

  • When did momondo last update prices for flights from Portland Airport to Greenville Airport?

    Prices for flights from Portland Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to Greenville Airport?

  • How old do you have to be to fly from Portland Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Greenville?

Best airlines flying from Portland to Greenville

Compare and see reviews for airlines that fly from Portland to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $302Free CancellationRating
7.9
7,954 reviews
Search Delta flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights
American AirlinesPriceFrom $350Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $367Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
Alaska AirlinesPriceFrom $476Free CancellationRating
8.0
10,000 reviews
Search Alaska Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Greenville with flexible booking policies on momondo?

Flights from Portland to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Portland to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from Portland.

I’m not ready to book a flight from Portland to Greenville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Greenville, momondo offers a useful price alert feature which will track prices for flights to Greenville from Portland and alert you when they change.

An easier way to manage your Greenville trip

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