What airlines fly to Missouri?

American Airlines, Southwest and Delta are the top three most popular airlines that fly to Missouri from Portland, Maine according to our data. American Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 7 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Portland to Missouri?

Delta, Southwest, and American Airlines are the most popular carriers operating from Portland to Missouri

When did momondo last update prices for flights from Portland Airport to Missouri?

Prices for flights from Portland Airport to Missouri are updated daily.

How many operators does momondo search for flights from Portland Airport to Missouri?

There are 4 operators available for flights from Portland Airport to Missouri as of February 2026.

How old do you have to be to fly from Portland Airport to Missouri?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$150 Cheap Flights from Portland to Missouri in 2026

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Find the cheapest flights from Portland, Maine to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:07 am - 4:41 pm

PWM

STL

10h 34m

1 stop

7:05 am - 11:22 pm

STL

PWM

15h 17m

1 stop

$305American Airlines

Wed, May 13 - Sat, May 16

6:01 pm - 11:46 pm

PWM

STL

6h 45m

1 stop

7:05 am - 11:27 pm

STL

PWM

15h 22m

1 stop

$307American Airlines

Wed, Apr 15 - Mon, Apr 20

6:01 pm - 11:46 pm

PWM

STL

6h 45m

1 stop

12:27 pm - 12:13 am

STL

PWM

10h 46m

1 stop

$315American Airlines

Thu, Apr 9 - Tue, Apr 14

4:45 pm - 9:57 pm

PWM

SGF

6h 12m

1 stop

6:00 am - 2:14 pm

SGF

PWM

7h 14m

1 stop

$329United Airlines

Fri, May 8 - Tue, May 12

2:30 pm - 7:19 pm

PWM

MCI

5h 49m

1 stop

4:48 pm - 11:22 pm

MCI

PWM

5h 34m

1 stop

$332Delta

Wed, Apr 1 - Mon, Apr 6

11:45 am - 4:31 pm

PWM

STL

5h 46m

1 stop

4:21 pm - 11:22 pm

STL

PWM

6h 01m

1 stop

$335Delta

Thu, Mar 26 - Mon, Mar 30

4:50 pm - 10:40 pm

PWM

MCI

6h 50m

1 stop

1:40 pm - 10:35 pm

MCI

PWM

7h 55m

2 stops

$338Southwest

Thu, Apr 9 - Tue, Apr 14

6:01 pm - 11:46 pm

PWM

STL

6h 45m

1 stop

6:29 am - 2:37 pm

STL

PWM

7h 08m

1 stop

$342American Airlines

Thu, Apr 9 - Tue, Apr 14

2:50 pm - 10:55 pm

PWM

MCI

9h 05m

2 stops

12:20 pm - 10:35 pm

MCI

PWM

9h 15m

2 stops

$343Southwest

Thu, Apr 9 - Tue, Apr 14

4:28 pm - 9:59 pm

PWM

MCI

6h 31m

1 stop

6:15 am - 2:20 pm

MCI

PWM

7h 05m

1 stop

$347United Airlines

Wed, Apr 8 - Tue, Apr 14

Delta flights from Portland, Maine to Missouri

Our best Delta deals on Portland, Maine to Missouri flight tickets

Delta

Apr 1

PWM2:30 pmPortland

5h 49m

1 stop

MCI7:19 pmKansas City

Apr 6

MCI4:48 pmKansas City

5h 34m

1 stop

PWM11:22 pmPortland

$332

Delta

Mar 26

PWM11:45 amPortland

5h 46m

1 stop

STL4:31 pmLambert-St Louis

Mar 30

STL4:21 pmLambert-St Louis

6h 01m

1 stop

PWM11:22 pmPortland

$335

Delta

May 7

PWM6:02 amPortland

7h 21m

1 stop

STL12:23 pmLambert-St Louis

May 10

STL7:15 amLambert-St Louis

4h 55m

1 stop

PWM1:10 pmPortland

$377

American Airlines flights from Portland, Maine to Missouri

Our best American Airlines deals on Portland, Maine to Missouri flight tickets

American Airlines

May 13

PWM7:07 amPortland

10h 34m

1 stop

STL4:41 pmLambert-St Louis

May 16

STL7:05 amLambert-St Louis

15h 17m

1 stop

PWM11:22 pmPortland

$305

American Airlines

Apr 15

PWM6:01 pmPortland

6h 45m

1 stop

STL11:46 pmLambert-St Louis

Apr 20

STL7:05 amLambert-St Louis

15h 22m

1 stop

PWM11:27 pmPortland

$307

American Airlines

Apr 9

PWM6:01 pmPortland

6h 45m

1 stop

STL11:46 pmLambert-St Louis

Apr 14

STL12:27 pmLambert-St Louis

10h 46m

1 stop

PWM12:13 amPortland

$315

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/13

7:07 am-4:41 pm

1 stop10h 34m

Lambert-St Louis

Sat 5/16

7:05 am-11:22 pm

1 stop15h 17m

$305

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 4/15

6:01 pm-11:46 pm

1 stop6h 45m

Lambert-St Louis

Mon 4/20

7:05 am-11:27 pm

1 stop15h 22m

$307

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 4/9

6:01 pm-11:46 pm

1 stop6h 45m

Lambert-St Louis

Tue 4/14

12:27 pm-12:13 am

1 stop10h 46m

$315

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Fri 5/8

4:45 pm-9:57 pm

1 stop6h 12m

Springfield-Branson

Tue 5/12

6:00 am-2:14 pm

1 stop7h 14m

$329

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 4/1

2:30 pm-7:19 pm

1 stop5h 49m

Kansas City

Mon 4/6

4:48 pm-11:22 pm

1 stop5h 34m

$332

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 3/26

11:45 am-4:31 pm

1 stop5h 46m

Lambert-St Louis

Mon 3/30

4:21 pm-11:22 pm

1 stop6h 01m

$335

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Thu 4/9

4:50 pm-10:40 pm

1 stop6h 50m

Kansas City

Tue 4/14

1:40 pm-10:35 pm

2 stops7h 55m

$338

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 4/9

6:01 pm-11:46 pm

1 stop6h 45m

Lambert-St Louis

Tue 4/14

6:29 am-2:37 pm

1 stop7h 08m

$342

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Thu 4/9

2:50 pm-10:55 pm

2 stops9h 05m

Kansas City

Tue 4/14

12:20 pm-10:35 pm

2 stops9h 15m

$343

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 4/8

4:28 pm-9:59 pm

1 stop6h 31m

Kansas City

Tue 4/14

6:15 am-2:20 pm

1 stop7h 05m

$347

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland, Maine to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from Portland, Maine to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $333. If you aren’t able to travel to Missouri during the month of September, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $334.

Can stopping save me money on Portland, Maine to Missouri flights?

You could potentially save up to 34% on your flight if you consider stops on a Portland, Maine to Missouri flight.

Cheap Portland, Maine to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Missouri

Fastest flight time	4h 54m
Direct flights	None

The fastest flight from Portland, Maine to Missouri takes 4h 54m

There are no direct flights from Portland, Maine to Missouri. There are no popular flight routes from Portland, Maine to Missouri.

Search flight deals

When did momondo last update prices for flights from Portland Airport to Missouri?
Prices for flights from Portland Airport to Missouri are updated daily.
How many operators does momondo search for flights from Portland Airport to Missouri?
There are 4 operators available for flights from Portland Airport to Missouri as of February 2026.
How old do you have to be to fly from Portland Airport to Missouri?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Portland, Maine to Missouri

Compare and see reviews for airlines that fly from Portland, Maine to Missouri with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $236	Free Cancellation	Rating 7.9 8,245 reviews	Search Delta flights
Southwest	PriceFrom $237	Free Cancellation	Rating 8.0 4,303 reviews	Search Southwest flights
American Airlines	PriceFrom $243	Free Cancellation	Rating 7.1 11,367 reviews	Search American Airlines flights
United Airlines	PriceFrom $267	Free Cancellation	Rating 7.4 9,363 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from Portland.

Can I find flights from Portland to Missouri with flexible booking policies on momondo?

All flight searches from Portland to Missouri on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Missouri?

Once all potential Portland to Missouri flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Missouri right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Missouri flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.