What airlines fly to Missouri?

American Airlines, Southwest and Delta are the top three most popular airlines that fly to Missouri from Portland, Maine according to our data. American Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 6 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Portland to Missouri?

Delta and United Airlines are the most popular carriers operating from Portland to Missouri

When did momondo last update prices for flights from Portland Airport to Missouri?

Prices for flights from Portland Airport to Missouri are updated daily.

How many operators does momondo search for flights from Portland Airport to Missouri?

There are 4 operators available for flights from Portland Airport to Missouri as of August 2026.

How old do you have to be to fly from Portland Airport to Missouri?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$129 Cheap Flights from Portland, Maine to Missouri in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Portland, Maine to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 10:26 amPWM Portland-MCI Kansas City

5h 26m1 stop Chicago O'Hare Intl

6:00 am - 2:38 pmMCI Kansas City-PWM Portland

7h 38m1 stop Chicago O'Hare Intl

$255United Airlines

Wed, Oct 14 - Wed, Oct 21

6:00 am - 10:26 amPWM Portland-MCI Kansas City

5h 26m1 stop Chicago O'Hare Intl

11:50 am - 7:24 pmMCI Kansas City-PWM Portland

6h 34m1 stop Washington, D.C. Dulles Intl

$255United Airlines

Wed, Oct 14 - Wed, Oct 21

6:00 am - 11:16 amPWM Portland-MCI Kansas City

6h 16m1 stop Philadelphia

4:30 pm - 10:31 pmMCI Kansas City-PWM Portland

5h 01m1 stop Philadelphia

$255American Airlines

Wed, Oct 14 - Wed, Oct 21

12:38 pm - 5:35 pmPWM Portland-MCI Kansas City

5h 57m1 stop Chicago O'Hare Intl

5:26 am - 11:59 amMCI Kansas City-PWM Portland

5h 33m1 stop Chicago O'Hare Intl

$255American Airlines

Sat, Nov 7 - Mon, Nov 9

6:00 am - 10:26 amPWM Portland-MCI Kansas City

5h 26m1 stop Chicago O'Hare Intl

6:00 am - 2:38 pmMCI Kansas City-PWM Portland

7h 38m1 stop Chicago O'Hare Intl

$257United Airlines

Wed, Oct 14 - Wed, Oct 21

7:30 am - 12:11 pmPWM Portland-MCI Kansas City

5h 41m1 stop Philadelphia

5:00 am - 1:05 pmMCI Kansas City-PWM Portland

7h 05m1 stop Chicago O'Hare Intl

$257American Airlines

Wed, Sep 9 - Wed, Sep 16

6:30 am - 11:43 amPWM Portland-STL Lambert-St Louis

6h 13m1 stop New York LaGuardia

2:30 pm - 11:28 pmSTL Lambert-St Louis-PWM Portland

7h 58m1 stop Atlanta Hartsfield-Jackson

$281Delta

Wed, Sep 16 - Mon, Sep 21

6:00 am - 12:32 pmPWM Portland-STL Lambert-St Louis

7h 32m1 stop Atlanta Hartsfield-Jackson

2:30 pm - 11:28 pmSTL Lambert-St Louis-PWM Portland

7h 58m1 stop Atlanta Hartsfield-Jackson

$281Delta

Sat, Sep 19 - Tue, Sep 22

12:45 pm - 6:05 pmPWM Portland-STL Lambert-St Louis

6h 20m1 stop Baltimore/Washington

6:35 am - 2:45 pmSTL Lambert-St Louis-PWM Portland

7h 10m1 stop Baltimore/Washington

$282Southwest

Mon, Nov 16 - Thu, Nov 19

3:25 pm - 9:55 pmPWM Portland-STL Lambert-St Louis

7h 30m2 stops Baltimore/Washington Nashville Intl

6:35 am - 2:45 pmSTL Lambert-St Louis-PWM Portland

7h 10m1 stop Baltimore/Washington

$287Southwest

Mon, Nov 16 - Thu, Nov 19

Cheap last minute flights

Enter your travel dates to find the best prices.

6:03 am - 10:25 amPWM Portland-MCI Kansas City

5h 22m1 stop Chicago O'Hare Intl

6:00 am - 3:51 pmMCI Kansas City-PWM Portland

8h 51m1 stop Denver Intl

$589United Airlines

Sat, Aug 15 - Sat, Aug 22

7:40 am - 12:20 pmPWM Portland-MCI Kansas City

5h 40m1 stop Chicago O'Hare Intl

11:22 am - 5:42 pmMCI Kansas City-PWM Portland

5h 20m1 stop Chicago O'Hare Intl

$589United Airlines

Sat, Aug 15 - Sat, Aug 22

6:03 am - 10:25 amPWM Portland-MCI Kansas City

5h 22m1 stop Chicago O'Hare Intl

1:08 pm - 11:32 pmMCI Kansas City-PWM Portland

9h 24m2 stops Chicago O'Hare Intl Newark

$594United Airlines

Sat, Aug 15 - Sat, Aug 22

5:40 am - 2:40 pmPWM Portland-MCI Kansas City

10h 00m2 stops Baltimore/Washington Orlando

8:25 am - 9:00 pmMCI Kansas City-PWM Portland

11h 35m2 stops Orlando Baltimore/Washington

$599Southwest

Sat, Aug 15 - Sat, Aug 22

7:25 am - 3:20 pmPWM Portland-MCI Kansas City

8h 55m2 stops Baltimore/Washington Lambert-St Louis

8:25 am - 9:00 pmMCI Kansas City-PWM Portland

11h 35m2 stops Orlando Baltimore/Washington

$599Southwest

Sat, Aug 15 - Sat, Aug 22

9:52 am - 8:44 pmPWM Portland-STL Lambert-St Louis

11h 52m1 stop New York LaGuardia

7:00 am - 10:15 pmSTL Lambert-St Louis-PWM Portland

14h 15m1 stop Washington, D.C. Reagan-National

$791American Airlines

Wed, Aug 19 - Sat, Aug 22

7:05 am - 4:50 pmPWM Portland-STL Lambert-St Louis

10h 45m1 stop Charlotte Douglas

7:00 am - 10:15 pmSTL Lambert-St Louis-PWM Portland

14h 15m1 stop Washington, D.C. Reagan-National

$829American Airlines

Tue, Aug 18 - Sat, Aug 22

8:50 am - 5:27 pmPWM Portland-STL Lambert-St Louis

9h 37m1 stop Washington, D.C. Reagan-National

7:00 am - 4:33 pmSTL Lambert-St Louis-PWM Portland

8h 33m1 stop Washington, D.C. Reagan-National

$869American Airlines

Tue, Aug 18 - Sat, Aug 22

2:50 pm - 10:10 pmPWM Portland-STL Lambert-St Louis

8h 20m2 stops Baltimore/Washington Nashville Intl

6:45 am - 3:00 pmSTL Lambert-St Louis-PWM Portland

7h 15m1 stop Baltimore/Washington

$892Southwest

Wed, Aug 19 - Sat, Aug 22

6:30 am - 2:33 pmPWM Portland-STL Lambert-St Louis

9h 03m2 stops New York LaGuardia Atlanta Hartsfield-Jackson

6:30 am - 3:58 pmSTL Lambert-St Louis-PWM Portland

8h 28m2 stops Detroit Metropolitan Wayne County New York LaGuardia

$1,564Delta

Tue, Aug 18 - Sat, Aug 22

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Delta flights from Portland, Maine to Missouri

Our best Delta deals on Portland, Maine to Missouri flight tickets

Delta

Sep 16

PWM6:30 amPortland

6h 13m

1 stop

STL11:43 amLambert-St Louis

Sep 22

STL5:30 pmLambert-St Louis

4h 47m

1 stop

PWM11:17 pmPortland

$281

Delta

Sep 17

PWM1:59 pmPortland

7h 07m

1 stop

STL8:06 pmLambert-St Louis

Sep 21

STL4:59 pmLambert-St Louis

5h 29m

1 stop

PWM11:28 pmPortland

$305

Delta

Nov 6

PWM5:28 pmPortland

5h 41m

1 stop

MCI10:09 pmKansas City

Nov 9

MCI6:00 amKansas City

6h 03m

1 stop

PWM1:03 pmPortland

$331

American Airlines flights from Portland, Maine to Missouri

Our best American Airlines deals on Portland, Maine to Missouri flight tickets

American Airlines

Sep 10

PWM6:30 amPortland

6h 18m

1 stop

MCI11:48 amKansas City

Sep 16

MCI4:22 pmKansas City

6h 23m

1 stop

PWM11:45 pmPortland

$275

American Airlines

Sep 9

PWM7:30 amPortland

5h 41m

1 stop

MCI12:11 pmKansas City

Sep 16

MCI4:22 pmKansas City

6h 23m

1 stop

PWM11:45 pmPortland

$287

American Airlines

Sep 17

PWM5:38 pmPortland

7h 49m

1 stop

STL12:27 amLambert-St Louis

Sep 23

STL5:13 pmLambert-St Louis

5h 32m

1 stop

PWM11:45 pmPortland

$288

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandKansas City

PWM Portland - MCI Kansas City

PWMMCI

Portland

Wed 10/14

6:00 am-10:26 am

1 stop5h 26m

Kansas City

Wed 10/21

6:00 am-2:38 pm

1 stop7h 38m

$255

PortlandKansas City

PWM Portland - MCI Kansas City

PWMMCI

Portland

Wed 10/14

6:00 am-10:26 am

1 stop5h 26m

Kansas City

Wed 10/21

11:50 am-7:24 pm

1 stop6h 34m

$255

Quickest round-trip

PortlandKansas City

PWM Portland - MCI Kansas City

PWMMCI

Portland

Wed 10/14

6:00 am-11:16 am

1 stop6h 16m

Kansas City

Wed 10/21

4:30 pm-10:31 pm

1 stop5h 01m

$255

PortlandKansas City

PWM Portland - MCI Kansas City

PWMMCI

Portland

Sat 11/7

12:38 pm-5:35 pm

1 stop5h 57m

Kansas City

Mon 11/9

5:26 am-11:59 am

1 stop5h 33m

$255

PortlandKansas City

PWM Portland - MCI Kansas City

PWMMCI

Portland

Wed 10/14

6:00 am-10:26 am

1 stop5h 26m

Kansas City

Wed 10/21

6:00 am-2:38 pm

1 stop7h 38m

$257

PortlandKansas City

PWM Portland - MCI Kansas City

PWMMCI

Portland

Wed 9/9

7:30 am-12:11 pm

1 stop5h 41m

Kansas City

Wed 9/16

5:00 am-1:05 pm

1 stop7h 05m

$257

PortlandSt. Louis

PWM Portland - STL Lambert-St Louis

PWMSTL

Portland

Wed 9/16

6:30 am-11:43 am

1 stop6h 13m

Lambert-St Louis

Mon 9/21

2:30 pm-11:28 pm

1 stop7h 58m

$281

PortlandSt. Louis

PWM Portland - STL Lambert-St Louis

PWMSTL

Portland

Sat 9/19

6:00 am-12:32 pm

1 stop7h 32m

Lambert-St Louis

Tue 9/22

2:30 pm-11:28 pm

1 stop7h 58m

$281

PortlandSt. Louis

PWM Portland - STL Lambert-St Louis

PWMSTL

Portland

Mon 11/16

12:45 pm-6:05 pm

1 stop6h 20m

Lambert-St Louis

Thu 11/19

6:35 am-2:45 pm

1 stop7h 10m

$282

PortlandSt. Louis

PWM Portland - STL Lambert-St Louis

PWMSTL

Portland

Mon 11/16

3:25 pm-9:55 pm

2 stops7h 30m

Lambert-St Louis

Thu 11/19

6:35 am-2:45 pm

1 stop7h 10m

$287

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland, Maine to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from Portland, Maine to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $415. If you aren’t able to travel to Missouri during the month of September, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $419.

Cheap Portland, Maine to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Missouri

Fastest flight time	4h 25m
Direct flights	None

The fastest flight from Portland, Maine to Missouri takes 4h 25m

There are no direct flights from Portland, Maine to Missouri. There are no popular flight routes from Portland, Maine to Missouri.

Search flight deals

Frequently asked questions about flying from Portland, Maine to Missouri

When did momondo last update prices for flights from Portland Airport to Missouri?
Prices for flights from Portland Airport to Missouri are updated daily.
How many operators does momondo search for flights from Portland Airport to Missouri?
There are 4 operators available for flights from Portland Airport to Missouri as of August 2026.
How old do you have to be to fly from Portland Airport to Missouri?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Portland, Maine to Missouri

Compare and see reviews for airlines that fly from Portland, Maine to Missouri with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $262	Free Cancellation	Rating 7.1 11,941 reviews	Search American Airlines flights
Delta	PriceFrom $268	Free Cancellation	Rating 7.8 8,508 reviews	Search Delta flights
United Airlines	PriceFrom $328	Free Cancellation	Rating 7.4 10,111 reviews	Search United Airlines flights
Southwest	PriceFrom $332	Free Cancellation	Rating 8.0 4,219 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from Portland.

Can I find flights from Portland to Missouri with flexible booking policies on momondo?

All flight searches from Portland to Missouri on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Missouri?

Once all potential Portland to Missouri flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Missouri right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Missouri flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.