What is the cheapest airline that flies from Portland to Missouri?

Delta, American Airlines, and Southwest are the most popular carriers operating from Portland to Missouri

What airlines fly to Missouri?

American Airlines, Southwest and Delta are the top three most popular airlines that fly to Missouri from Portland, Maine according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 7 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Portland Airport to Missouri?

Prices for flights from Portland Airport to Missouri are updated daily.

How many operators does momondo search for flights from Portland Airport to Missouri?

There are 4 operators available for flights from Portland Airport to Missouri as of April 2026.

How old do you have to be to fly from Portland Airport to Missouri?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$129 Cheap Flights from Portland to Missouri in 2026

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Find the cheapest flights from Portland, Maine to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:10 pm - 11:00 pm

PWM

STL

4h 50m

1 stop

3:45 pm - 10:55 pm

STL

PWM

6h 10m

1 stop

$299Southwest

Tue, Jun 16 - Wed, Jun 24

7:10 pm - 11:00 pm

PWM

STL

4h 50m

1 stop

3:15 pm - 10:55 pm

STL

PWM

6h 40m

2 stops

$304Southwest

Tue, Jun 16 - Wed, Jun 24

5:36 pm - 12:26 am

PWM

MCI

7h 50m

1 stop

4:20 pm - 12:37 am

MCI

PWM

7h 17m

1 stop

$313American Airlines

Tue, Jun 23 - Tue, Jun 30

6:00 am - 12:20 pm

PWM

STL

7h 20m

1 stop

4:25 pm - 12:43 am

STL

PWM

7h 18m

1 stop

$315Delta

Thu, May 7 - Wed, May 13

7:10 am - 1:22 pm

PWM

STL

7h 12m

1 stop

6:35 am - 3:09 pm

STL

PWM

7h 34m

1 stop

$316American Airlines

Sat, May 16 - Tue, May 19

2:35 pm - 10:29 pm

PWM

SGF

8h 54m

2 stops

6:00 am - 12:22 pm

SGF

PWM

5h 22m

1 stop

$354Delta

Fri, Aug 21 - Mon, Aug 24

6:25 pm - 10:44 pm

PWM

STL

5h 19m

1 stop

6:00 am - 1:25 pm

STL

PWM

6h 25m

1 stop

$379United Airlines

Thu, Jun 4 - Sun, Jun 7

9:52 am - 11:57 pm

PWM

STL

15h 05m

1 stop

6:33 pm - 4:16 pm

STL

PWM

20h 43m

2 stops

$381Multiple Airlines

Sat, May 23 - Tue, May 26

6:00 am - 10:42 am

PWM

SGF

5h 42m

1 stop

3:07 pm - 9:51 pm

SGF

PWM

5h 44m

1 stop

$406United Airlines

Fri, May 29 - Sat, Jun 6

9:52 am - 9:29 am

PWM

MCI

24h 37m

1 stop

6:24 pm - 7:16 pm

MCI

PWM

23h 52m

2 stops

$412Multiple Airlines

Sat, May 16 - Wed, May 20

Southwest flights from Portland, Maine to Missouri

Our best Southwest deals on Portland, Maine to Missouri flight tickets

Southwest

Jun 16

PWM7:10 pmPortland

4h 50m

1 stop

STL11:00 pmLambert-St Louis

Jun 24

STL3:45 pmLambert-St Louis

6h 10m

1 stop

PWM10:55 pmPortland

$299

Southwest

Jun 16

PWM7:10 pmPortland

4h 50m

1 stop

STL11:00 pmLambert-St Louis

Jun 24

STL3:15 pmLambert-St Louis

6h 40m

2 stops

PWM10:55 pmPortland

$304

Southwest

Jun 23

PWM5:30 amPortland

5h 15m

1 stop

MCI9:45 amKansas City

Jun 30

MCI2:30 pmKansas City

7h 25m

2 stops

PWM10:55 pmPortland

$363

American Airlines flights from Portland, Maine to Missouri

Our best American Airlines deals on Portland, Maine to Missouri flight tickets

American Airlines

Jun 23

PWM5:36 pmPortland

7h 50m

1 stop

MCI12:26 amKansas City

Jun 30

MCI4:20 pmKansas City

7h 17m

1 stop

PWM12:37 amPortland

$313

American Airlines

May 16

PWM7:10 amPortland

7h 12m

1 stop

STL1:22 pmLambert-St Louis

May 19

STL6:35 amLambert-St Louis

7h 34m

1 stop

PWM3:09 pmPortland

$316

American Airlines

Jun 13

PWM5:57 pmPortland

6h 47m

1 stop

STL11:44 pmLambert-St Louis

Jun 17

STL6:15 amLambert-St Louis

7h 09m

1 stop

PWM2:24 pmPortland

$363

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 6/16

7:10 pm-11:00 pm

1 stop4h 50m

Lambert-St Louis

Wed 6/24

3:45 pm-10:55 pm

1 stop6h 10m

$299

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 6/16

7:10 pm-11:00 pm

1 stop4h 50m

Lambert-St Louis

Wed 6/24

3:15 pm-10:55 pm

2 stops6h 40m

$304

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Tue 6/23

5:36 pm-12:26 am

1 stop7h 50m

Kansas City

Tue 6/30

4:20 pm-12:37 am

1 stop7h 17m

$313

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 5/7

6:00 am-12:20 pm

1 stop7h 20m

Lambert-St Louis

Wed 5/13

4:25 pm-12:43 am

1 stop7h 18m

$315

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 5/16

7:10 am-1:22 pm

1 stop7h 12m

Lambert-St Louis

Tue 5/19

6:35 am-3:09 pm

1 stop7h 34m

$316

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Fri 8/21

2:35 pm-10:29 pm

2 stops8h 54m

Springfield-Branson

Mon 8/24

6:00 am-12:22 pm

1 stop5h 22m

$354

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 6/4

6:25 pm-10:44 pm

1 stop5h 19m

Lambert-St Louis

Sun 6/7

6:00 am-1:25 pm

1 stop6h 25m

$379

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 5/23

9:52 am-11:57 pm

1 stop15h 05m

Lambert-St Louis

Tue 5/26

6:33 pm-4:16 pm

2 stops20h 43m

$381

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Fri 5/29

6:00 am-10:42 am

1 stop5h 42m

Springfield-Branson

Sat 6/6

3:07 pm-9:51 pm

1 stop5h 44m

$406

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Sat 5/16

9:52 am-9:29 am

1 stop24h 37m

Kansas City

Wed 5/20

6:24 pm-7:16 pm

2 stops23h 52m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland, Maine to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from Portland, Maine to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $333. If you aren’t able to travel to Missouri during the month of September, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $344.

Can stopping save me money on Portland, Maine to Missouri flights?

You could potentially save up to 38% on your flight if you consider stops on a Portland, Maine to Missouri flight.

Cheap Portland, Maine to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Missouri

Fastest flight time	4h 50m
Direct flights	None

The fastest flight from Portland, Maine to Missouri takes 4h 50m

There are no direct flights from Portland, Maine to Missouri. There are no popular flight routes from Portland, Maine to Missouri.

Search flight deals

Frequently asked questions about flying from Portland, Maine to Missouri

When did momondo last update prices for flights from Portland Airport to Missouri?
Prices for flights from Portland Airport to Missouri are updated daily.
How many operators does momondo search for flights from Portland Airport to Missouri?
There are 4 operators available for flights from Portland Airport to Missouri as of April 2026.
How old do you have to be to fly from Portland Airport to Missouri?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Portland, Maine to Missouri

Compare and see reviews for airlines that fly from Portland, Maine to Missouri with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $236	Free Cancellation	Rating 7.9 8,422 reviews	Search Delta flights
Southwest	PriceFrom $237	Free Cancellation	Rating 8.0 4,327 reviews	Search Southwest flights
American Airlines	PriceFrom $243	Free Cancellation	Rating 7.1 11,620 reviews	Search American Airlines flights
United Airlines	PriceFrom $328	Free Cancellation	Rating 7.4 9,604 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from Portland.

Can I find flights from Portland to Missouri with flexible booking policies on momondo?

All flight searches from Portland to Missouri on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Missouri?

Once all potential Portland to Missouri flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to Missouri right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Portland to Missouri flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.