Cheap flights from Phoenix Sky Harbor Intl Airport to Knoxville from $125

The month of January is, on average, the cheapest month to fly to Knoxville from Phoenix Sky Harbor Intl Airport, with most prices found around $263. If you aren’t able to travel during the month of January, then book flights to Knoxville from Phoenix Sky Harbor Intl Airport during February instead. Flights to Knoxville in February, while not as cheap as those in January, still average around $268.

The cheapest day to depart from Phoenix Sky Harbor Intl Airport to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $124. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Phoenix Sky Harbor Intl Airport to Knoxville for around $292.

In the morning is the cheapest time of day to fly from Phoenix Sky Harbor Intl Airport to Knoxville when you can find flight prices for as low as $205. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $259.

Fly from Phoenix Sky Harbor Intl to Knoxville McGhee Tyson for the best Phoenix Sky Harbor Intl - Knoxville McGhee Tyson flight prices

You are more likely to see cheaper flights to Knoxville from Phoenix Sky Harbor Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $295 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Phoenix Sky Harbor Intl Airport for as low as $225 on momondo.

There is only 1 cabin class available to choose from on Phoenix Sky Harbor Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 36% on your flight if you consider stops on a Phoenix Sky Harbor Intl Airport to Knoxville flight.

As of March 2026, prices for Phoenix Sky Harbor Intl Airport to Knoxville flights are approximately 41% more expensive when compared to flights at the same time last year.

Frontier, Allegiant Air, and American Airlines are the most popular carriers operating from Phoenix Sky Harbor Intl to Knoxville McGhee Tyson

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from Phoenix Sky Harbor Intl Airport according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

Dallas (DFW) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Flights via Chicago (ORD) offer the lowest average round-trip price of $228.

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 5h 32m.

Dallas (DFW) has the shortest average layover time for this route: 2h 03m.